Do
not start an antibiotic on your own. When several people become ill after the same meal, it is often toxin- or virus-related and usually settles with supportive care. Antibiotics often do not help and can cause side effects, antibiotic-associated diarrhea, and resistance. The main treatment is hydration, as noted in
Yamada’s Textbook of Gastroenterology (acute diarrhea treatment section), and CDC similarly advises that antibiotics are not routinely recommended for food poisoning such as
C. perfringens illness (
CDC clinical guidance).
A clinician may consider stool testing and targeted antibiotics only in selected situations, such as high fever, bloody diarrhea, severe illness, or a confirmed bacterial outbreak.