Question 1: A 35-year-old woman presents with pelvic pain, and a mass descending PV with increases in size on coughing. She is posted for a Fothergill repair. Which of the following is false about this procedure? It is also known as Manchester operation It does not preserve the reproductive functions Recurrent abortions are a sequelae of this operation Amputation of cervix is done Question 2: A 62-year-old woman complains of constipation and difficulty having bowel movements. She states that she often needs to use her fingers to push her vagina backward to achieve a bowel movement. Her history is otherwise unremarkable. Which of the following is the best treatment for this patient? Hysterectomy Anterior colporrhaphy Posterior colporrhaphy Resection and repair of enterocele Question 3: A 35-year-old woman is undergoing a hysterectomy for u v prolapse. The surgeon is attempt- ing to ensure that the patient does not have subsequent vaginal vault pro- lapse. One step that is taken is to use suture to fix the vaginal vault to the uterosacral ligaments. The patient is also noted to have a spacious cul-de-sac area. Which of the following techniques may be used to further decrease the likelihood of vaginal vault prolapse? Obliteration of the vaginal cavity Fixation of the vagina to the anterior abdominal wall Obliteration of the cul-de-sac Prophylactic pessary Question 4: A 23-year-old in the postnatal period after her first delivery developed a uterine prolapse . What would be the most appropriate management in her case? Ring pessary Le Forte's repair Abdominal sling operation Fothergill operation Question 5: A multiparous woman has a previous history of birth trauma with injury to the uterosacral and cardinal ligaments. According to DeLancey's classification, which level of uterine support is affected in this patient? Level 2 Level 3 Level 1 Level 4 Question 6: The risk of endometrial cancer is highest with the following histological pattern of endometrial hyperplasia: a. b. c. d. Simple hyperplasia without atypia Simple hyperplasia with atypia Complex hyperplasia without atypia Complex hyperplasia with atypia Question 7: The risk of complex hyperplasia of endometrium with atypia progressing to malignancy in a postmenopausal woman is: a. b. c. d. 3% 8% 15% 28% Question 8: Percentage change of cystic glandular hyperplasia turning to malignancy: a. b. c. d. 0.1% 2% 1% 10% Question 9: Endometrial hyperplasia is seen in: a. b. c. d. Endodermal sinus tumor Dysgerminoma PCOD Ca cervix Question 10: What is the ideal treatment for a 55-years-female with Simple hyperplasia of endometrium with Atypia? a. b. c. d. Simple hysterectomy Medroxy progesterone acetate (MPA) Levonorgesterol (LNG) IUCD Question 11: What are the cardinal movements of labour? Engagement-descent-flexion-internal rotation-extension-external rotation-expulsion Engagement-flexion-descent-internal rotation-extension-expulsion Engagement-flexion-descent-external rotation-expulsion Engagement-extension-internal rotation-external rotation-expulsion Question 12: Which of the following is a prerequisite for internal rotation of the fetal head for a woman in labor? A) B) C) D) Straightening of fetal body Tone of transversus abdominis Well-extended head Tone of levator ani muscles Question 13: Which of the following statements is true regarding the internal rotation of the fetal head? Occiput turns towards the transverse axis Rotation is not essential when the fetus is unusually small Internal rotation is followed by external rotation Rotation is earlier in primigravida than in multigravida Question 14: Which of the following is not a part of a partograph? Fetal heart rate Maternal heart rate Maternal temperature Fetal temperature Question 15: Which of the following is false regarding the modified WHO partogram? A) B) C) Right side of alert line indicates immediate referral to First Referral Unit (FRU) Alert and action line are separated by a difference of 4 hours Each small square in partogram is equal to 1 hour Partograph recording should be started once the cervical dilatation reaches 4 cm Question 16: Which of the following are not risk factors for developing Gestational Diabetes? family history of diabetes gestational diabetes in previous pregnancy persistent glycosuria obesity in first degree relatives Question 17: A primigravida at 30 weeks of gestation is admitted with preterm labor contractions. She was diagnosed with GDM on screening. Which of the following tocolytic drugs should be avoided in her? Magnesium sulfate Nifedipine Terbutaline Indomethacin Question 18: A pregnant woman has GDM, her blood glucose levels are well controlled on Insulin. What will be the appropriate gestational age for her delivery? Options: 37 weeks 39 weeks 38 weeks 40 weeks Question 19: Which of the following complications is unlikely in a patient with gestational diabetes? Abortion Preeclampsia Respiratory distress syndrome Oligohydramnios Question 20: A baby was born at 37 weeks gestation with a birth weight of 4.9kg to mother of GDM. Which of the following complications is likely to be seen in this neonate? Polycythemia Hypercalcemia Hyperglycemia Hypermagnesemia Question 21: Pregnancy-induced hypertension typically occurs after how many weeks of gestation? 10 weeks 20 weeks 30 weeks 36 weeks Question 22: Which of the following is not a risk factor for PIH? Nulliparity Chronic hypertension Multiple gestation Smoking Question 23: Which of the following is the most specific sign of severe preeclampsia? Edema Proteinuria >5 g/day Hemolysis Blood pressure ≥140/90 mmHg Question 24: Which antihypertensive is contraindicated in pregnancy? Methyldopa Labetalol Nifedipine ACE inhibitors Question 25: Which of the following is the most important pathophysiological factor in PIH? Increased plasma volume Increased cardiac output Defective trophoblastic invasion Hypovolemia Question 26: Which of the following is the most common cause of fetal growth restriction (FGR)? Chromosomal abnormalities Maternal hypertension Maternal diabetes Intrauterine infection Question 27: Fetal growth restriction is diagnosed when the estimated fetal weight is below which percentile for gestational age? 25th percentile 20th percentile 10th percentile 5th percentile Question 28: Which of the following Doppler findings is most suggestive of severe FGR? Increased middle cerebral artery resistance Reversed end-diastolic flow in umbilical artery Increased uterine artery diastolic flow Normal ductus venosus flow Question 29: Symmetrical FGR is most commonly associated with: Placental insufficiency Maternal anemia Genetic abnormalities Preeclampsia Question 30: Which of the following is the best initial method for diagnosing FGR? A. B. C. D. MRI of the fetus Amniocentesis Serial fundal height measurement Ultrasound for fetal biometry Question 31: The Rhesus blood group antigen complex is located on which chromosome? 16 14 4 1 Question 32: Antigens of which of the following blood group systems do not cause alloimmunization in a newborn/fetus? Kidd MNS Kell Lewis Question 33: A pregnant Rh-negative woman presents for her regular antenatal visit. Her Indirect Coombs test is negative. When would you give her prophylactic Anti-D? 28 weeks 24 weeks 28 weeks and then monthly thereafter 24 weeks and then monthly thereafter Question 34: Which of the following events in Rh-negative patients does not require Anti-D prophylaxis? Miscarriage Chorionic villi sampling Amniocentesis Postpartum hemorrhage Question 35: Chorionic villus sampling was performed on a G2P1 Rh-negative woman at 10 weeks of gestation. What is the dose of Anti-D immunoglobulin that should be administered? 50 microgram 100 microgram 150 microgram 300 microgram Question 36: Use of folic acid to prevent congenital malformation should be best initiated: During 1st trimester of pregnancy During 2nd trimester of pregnancy During 3rd trimester of pregnancy Before conception Question 37: A 22 year old G2P1 woman presents to the antenatal clinic at 24 weeks for a routine checkup. USG shows a normal for gestational age fetus in frank breech position, with no other abnormalities. What is the next best step in management 75g oral glucose stress test non stress tes external cephalic version lower segment caesarean section Question 38: Which of the following is not considered as a factor for a high risk pregnancy? obesity polyhydramnios anaemia previous caesarean section Question 39: Which of the following statements is not true regarding fetal souffle? a. b. c. d. it is a sharp whistling murmur synchronous with the fetal heart sounds it is due to rush of blood through the intervillous space it is heard in about 15% cases when present it is a diagnostic of pregnancy Question 40: An anxious pregnant woman came to you for a second opinion with the report of her biochemical screening tests. An increased level of human chorionic gonadotropin, as compared to normal pregnancy hcg levels, can be seen in all of the following conditions except: ectopic pregnancy hydatidiform mole trisomy 21 fetus multiple pregnancy Question 41: Initially, all fibroids are Intramural Submucosal Subserous Cervical Question 42: A 55-year-old lady comes with abnormal uterine bleeding. A hysterectomy was performed and the following specimen was retrieved. What is the diagnosis? Leiomyoma Endometrial carcinoma Endometrial polyp Adenomyosis Question 43: Which of the following best defines adenomyosis? Endometrial tissue located on the ovaries Endometrial tissue within the myometrium Endometrial tissue on the uterine serosa Endometrial tissue in the peritoneum Question 44: Which age group is adenomyosis most commonly seen in? Adolescents Women under 20 Women between 30–50 years Postmenopausal women Question 45: Infertility is defined as failure to conceive after how long of regular unprotected intercourse? 6 months 12 months 18 months 24 months Question 46: The most common cause of female infertility is: Uterine factor Cervical factor Tubal factor Ovulatory dysfunctio Question 47: All of the following are known risk factors for the development of ovarian carcinoma except: Family history of ovarian carcinoma Use of oral pills Use of Clomiphene BRCA - 1 positive individual Question 48: Which of the following strategy has been recommended to reduce the heredity risk for ovarian cancer in women with BRCA - 1 and BRCA - 2 mutations? Options: Use of oral contraceptive pills Screening with transvaginal ultrasound Screening with CA - 125 Prophylactic oophorectomy Question 49: Most common ovarian tumor in less than 20 years is: Options: Epithelial tumour Germ cell tumour Metastatic tumour Sexcord stromal tumour Question 50: According to WHO classification of ovarian tumours, Brenner tumor of ovary belongs to: Epithelial tumours Sex cord stromal tumours Germ cell tumours Metastatic tumours Answers from dutta

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I have enough context from the library plus my core Dutta-based knowledge to answer all 50 questions comprehensively. Let me now provide complete answers.

Complete Answers - Dutta's Obstetrics & Gynaecology


GYNAECOLOGY - Prolapse

Q1. False statement about Fothergill (Manchester) operation: Answer: B - It does not preserve reproductive functions
This is FALSE - the Fothergill/Manchester operation DOES preserve the uterus and thus preserves reproductive function (though fertility outcomes are poor due to cervical incompetence). All other statements are TRUE:
  • It IS called the Manchester operation (Donald-Fothergill)
  • Recurrent abortions ARE a sequelae (cervical incompetence after amputation)
  • Amputation of cervix IS done, with the cardinal ligaments sutured anterior to the cervix

Q2. Best treatment for rectocele (finger pressure needed to defecate): Answer: C - Posterior colporrhaphy
The patient's symptom of needing to splint (push the vaginal wall back) to defecate is the classic presentation of a rectocele (posterior vaginal wall prolapse). The repair is posterior colporrhaphy, which reinforces the rectovaginal fascia.

Q3. Technique to prevent vaginal vault prolapse with spacious cul-de-sac: Answer: C - Obliteration of the cul-de-sac (McCall culdoplasty)
A spacious cul-de-sac predisposes to enterocele and subsequent vault prolapse. McCall culdoplasty (obliteration of the cul-de-sac) at the time of hysterectomy reduces this risk. The uterosacral ligament fixation is already mentioned. Fixation to the anterior abdominal wall (sacrocolpopexy) is abdominal, not specifically indicated for cul-de-sac obliteration.

Q4. Most appropriate management for uterine prolapse in a 23-year-old postnatal woman: Answer: A - Ring pessary
She is young (23 years), in the postnatal period, and likely to recover with pelvic floor physiotherapy. A ring pessary is the most appropriate conservative, temporary measure. Definitive surgery (Le Forte's, Fothergill) is avoided in young women who may want future fertility. Ring pessary allows assessment after postpartum recovery (6 weeks minimum before any surgical intervention).

Q5. DeLancey level affected by uterosacral and cardinal ligament injury: Answer: C - Level 1
According to DeLancey's classification:
  • Level 1: Apical support - uterosacral and cardinal (Mackenrodt's) ligaments suspend the upper vagina/uterus
  • Level 2: Lateral attachment to arcus tendineus fascia pelvis (mid-vagina)
  • Level 3: Distal fusion to perineal body and levator ani
Cardinal and uterosacral ligament injury = Level 1 support failure.

GYNAECOLOGY - Endometrial Hyperplasia

Q6. Highest risk of endometrial cancer: Answer: D - Complex hyperplasia with atypia
Risk of progression to cancer (per Kurman):
  • Simple without atypia: ~1%
  • Complex without atypia: ~3%
  • Simple with atypia: ~8%
  • Complex with atypia: ~29% (~28-29%) - highest risk

Q7. Risk of complex hyperplasia with atypia progressing to malignancy: Answer: D - 28%
Approximately 28-29% of complex hyperplasia with atypia progresses to endometrial carcinoma (Kurman et al.). This is the widely cited figure in Dutta's.

Q8. Percentage of cystic glandular hyperplasia turning malignant: Answer: C - 1%
Cystic glandular hyperplasia (simple hyperplasia without atypia) has approximately 1% risk of malignant transformation. (Note: Some texts cite 0.1-1%; Dutta's classically states ~1%.)

Q9. Endometrial hyperplasia is seen in: Answer: C - PCOD (Polycystic Ovarian Disease)
PCOD causes chronic anovulation leading to unopposed estrogen stimulation of the endometrium, resulting in endometrial hyperplasia. Endodermal sinus tumor, dysgerminoma, and Ca cervix do not characteristically cause endometrial hyperplasia.

Q10. Ideal treatment for 55-year-old woman with simple hyperplasia WITH atypia: Answer: A - Simple hysterectomy
Atypical hyperplasia in a postmenopausal woman carries significant malignancy risk (~8% for simple with atypia, and coexisting carcinoma may already be present). Total hysterectomy is the treatment of choice. Progestogens (MPA, LNG-IUS) are reserved for pre-menopausal women desiring fertility or those unfit for surgery.

OBSTETRICS - Labour

Q11. Cardinal movements of labour (correct sequence): Answer: A - Engagement - Descent - Flexion - Internal rotation - Extension - External rotation (restitution) - Expulsion
This is the classic sequence per Dutta:
  1. Engagement
  2. Descent
  3. Flexion
  4. Internal rotation
  5. Extension
  6. External rotation (restitution)
  7. Expulsion

Q12. Prerequisite for internal rotation of fetal head: Answer: D - Tone of levator ani muscles
The gutter-shaped levator ani (pelvic floor) guides the occiput anteriorly during internal rotation. The well-flexed head (not extended) presents a smaller diameter, but the tone of levator ani is the specific prerequisite that mechanically rotates the occiput from transverse to anterior.

Q13. True statement about internal rotation of fetal head: Answer: C - Internal rotation is followed by external rotation
  • A: FALSE - occiput turns toward the ANTERIOR (symphysis pubis), not transverse
  • B: FALSE - rotation is always essential regardless of fetal size
  • C: TRUE - after extension and delivery of the head, external rotation (restitution) occurs
  • D: FALSE - internal rotation is earlier in multigravida (better pelvic floor tone) than primigravida

Q14. Not a part of a partograph: Answer: D - Fetal temperature
The partograph includes: fetal heart rate, fetal membranes/liquor, maternal blood pressure, pulse, temperature, urine output, cervical dilatation, descent of head, uterine contractions, drugs/IV fluids. Fetal temperature is NOT recorded (it cannot be measured during labour without invasive methods).

Q15. False statement about modified WHO partogram: Answer: A - Right side of alert line indicates immediate referral to FRU
FALSE. The area to the RIGHT of the ACTION line (not alert line) indicates need for immediate intervention/referral. The alert line is the first warning; the action line (4 hours to the right) triggers active management/referral. The other statements are true:
  • Alert and action lines are 4 hours apart ✓
  • Each small square = 1 hour ✓
  • Recording starts at 4 cm cervical dilatation ✓

OBSTETRICS - GDM

Q16. NOT a risk factor for Gestational Diabetes: Answer: D - Obesity in first-degree relatives
Risk factors for GDM include: family history of DM (first-degree relative with DM), previous GDM, persistent glycosuria, BMI >30 (maternal obesity), previous macrosomic baby, PCOS. Obesity in first-degree relatives (without the relative having diabetes) is not a recognized independent risk factor - it's the patient's own obesity that matters.

Q17. Tocolytic to avoid in GDM primigravida: Answer: C - Terbutaline
Beta-2 agonists (terbutaline, ritodrine, salbutamol) cause significant hyperglycemia by stimulating glycogenolysis and gluconeogenesis. They are contraindicated in women with GDM. Nifedipine and magnesium sulfate are preferred tocolytics in GDM.

Q18. Appropriate gestational age for delivery in well-controlled GDM on insulin: Answer: C - 38 weeks
Per current guidelines (and Dutta's):
  • Diet-controlled GDM: 40 weeks (or await spontaneous labour)
  • GDM on insulin, well controlled: 38-39 weeks
  • GDM with poor control/complications: 37-38 weeks
The most commonly cited answer for insulin-controlled GDM in Indian PG exams is 38 weeks.

Q19. Complication UNLIKELY in gestational diabetes: Answer: D - Oligohydramnios
GDM is associated with polyhydramnios (fetal hyperglycemia causes fetal polyuria), NOT oligohydramnios. Other associations:
  • Abortion: yes (especially early GDM/pregestational DM)
  • Preeclampsia: yes (increased risk)
  • RDS: yes (delayed lung maturity due to high insulin levels)

Q20. Likely complication in a 4.9 kg baby (macrosomic) born to GDM mother at 37 weeks: Answer: A - Polycythemia
Neonates of diabetic mothers are at risk of:
  • Polycythemia (due to fetal hypoxia stimulating erythropoietin)
  • Hypoglycemia (NOT hyperglycemia - insulin excess after birth)
  • Hypocalcemia (NOT hypercalcemia)
  • Hypomagnesemia (NOT hypermagnesemia)
The question asks what is "likely to be seen" - Polycythemia is correct. Note: Hypoglycemia is actually MORE common, but it is not listed. Among the given options, polycythemia is the correct answer.

OBSTETRICS - PIH / Pre-eclampsia

Q21. PIH typically occurs after how many weeks: Answer: B - 20 weeks
By definition, pregnancy-induced hypertension (gestational hypertension/pre-eclampsia) occurs after 20 weeks of gestation. Hypertension before 20 weeks suggests chronic (pre-existing) hypertension.

Q22. NOT a risk factor for PIH: Answer: D - Smoking
Paradoxically, smoking is actually protective against PIH/pre-eclampsia (possibly due to carbon monoxide effects on thromboxane). All others are established risk factors:
  • Nulliparity: yes
  • Chronic hypertension: yes
  • Multiple gestation: yes

Q23. Most specific sign of SEVERE pre-eclampsia: Answer: B - Proteinuria >5 g/day
Severe pre-eclampsia criteria include BP ≥160/110 mmHg, proteinuria >5g/24h, oliguria, cerebral symptoms, pulmonary edema, thrombocytopenia, HELLP. Edema is non-specific. BP ≥140/90 is the threshold for mild pre-eclampsia. Proteinuria >5 g/day (or 3+ on dipstick) is the most specific marker of severe pre-eclampsia among the options given.

Q24. Antihypertensive contraindicated in pregnancy: Answer: D - ACE inhibitors
ACE inhibitors (and ARBs) are absolutely contraindicated in pregnancy - they cause fetal renal tubular dysplasia, oligohydramnios, neonatal renal failure, and limb contractures (fetopathy). Methyldopa, labetalol, and nifedipine are all safe and used in pregnancy.

Q25. Most important pathophysiological factor in PIH: Answer: C - Defective trophoblastic invasion
The central pathophysiology of pre-eclampsia is abnormal/defective trophoblastic invasion of spiral arteries. This leads to high-resistance uteroplacental circulation, ischemia, and release of anti-angiogenic factors (sFlt-1, endoglin) causing endothelial dysfunction. PIH is associated with hypovolemia (not increased plasma volume) and reduced cardiac output.

OBSTETRICS - FGR

Q26. Most common cause of FGR: Answer: B - Maternal hypertension
Uteroplacental insufficiency due to maternal hypertension (PIH/chronic hypertension) is the most common cause of FGR, particularly asymmetric FGR. Chromosomal abnormalities and infections cause symmetric FGR but are less common overall.

Q27. FGR diagnosed when EFW is below which percentile: Answer: C - 10th percentile
FGR is defined as estimated fetal weight (EFW) or abdominal circumference below the 10th percentile for gestational age on ultrasound.

Q28. Doppler finding most suggestive of SEVERE FGR: Answer: B - Reversed end-diastolic flow in umbilical artery
Absent or reversed end-diastolic flow (REDF) in the umbilical artery indicates severely elevated placental resistance, reflecting critical compromise and is associated with high perinatal mortality. This is the most severe Doppler finding in FGR.

Q29. Symmetrical FGR most commonly associated with: Answer: C - Genetic abnormalities
Symmetrical (proportionate) FGR affects all fetal parameters equally and has an early onset. It is most commonly associated with:
  • Chromosomal/genetic abnormalities (trisomies, structural defects)
  • Congenital infections (TORCH)
  • Severe maternal malnutrition
Placental insufficiency and pre-eclampsia cause asymmetric FGR (late onset, brain-sparing).

Q30. Best initial method for diagnosing FGR: Answer: D - Ultrasound for fetal biometry
Ultrasound biometry (BPD, HC, AC, FL) is the gold standard for diagnosing FGR. Serial fundal height measurement is a screening tool but has low sensitivity/specificity. Ultrasound is the best initial diagnostic method.

OBSTETRICS - Rh Isoimmunization

Q31. Chromosome location of Rhesus blood group antigen complex: Answer: D - Chromosome 1
The RHD and RHCE genes are located on the short arm of chromosome 1 (1p36.11).

Q32. Blood group system that does NOT cause alloimmunization in fetus/newborn: Answer: D - Lewis
Lewis antigens (Le^a, Le^b) are plasma antigens absorbed onto red cell surfaces - they are NOT intrinsic RBC antigens and are not expressed on fetal/neonatal RBCs. Therefore, they cannot cause hemolytic disease of the newborn (HDN). Kell, Kidd, and MNS systems can all cause HDN.

Q33. When to give prophylactic Anti-D to Rh-negative woman with negative ICT: Answer: A - 28 weeks
The standard protocol for antenatal Anti-D prophylaxis in Rh-negative unsensitized women:
  • 28 weeks (and optionally at 34 weeks in some protocols)
  • Postpartum within 72 hours if baby is Rh-positive
Monthly administration is NOT standard. The answer is 28 weeks.

Q34. Event in Rh-negative patient that does NOT require Anti-D: Answer: D - Postpartum hemorrhage
Wait - this needs careful thought. PPH itself doesn't require Anti-D as an isolated indication; Anti-D is given postpartum based on baby's Rh status. However, all of the following DO require Anti-D: miscarriage (>12 weeks, some say all), CVS, amniocentesis.
Actually, postpartum hemorrhage per se is NOT a listed sensitizing event requiring Anti-D prophylaxis in standard protocols - Anti-D is given postpartum routinely regardless of PPH. But among the options, the intended answer is D - Postpartum hemorrhage as it is not a specific sensitizing event by itself (unlike the invasive procedures).

Q35. Dose of Anti-D after CVS at 10 weeks in Rh-negative woman: Answer: A - 50 micrograms
For procedures before 12 weeks gestation (including CVS, amniocentesis before 12 weeks, miscarriage before 12 weeks), the dose is 50 micrograms (250 IU). After 12 weeks, the standard dose is 300 micrograms (1500 IU).

OBSTETRICS - Antenatal Care

Q36. Folic acid for prevention of congenital malformations should be started: Answer: D - Before conception
Folic acid (5 mg/day for high-risk, 0.4-0.5 mg/day for low-risk) must be started periconceptionally - at least 1 month before conception and continued through the first trimester (up to 12 weeks). Neural tube closure occurs at 4-6 weeks, often before pregnancy is recognized.

Q37. Next best step for frank breech at 24 weeks in G2P1: Answer: A - 75g oral glucose tolerance test (not stress test)
Wait - the options say "75g oral glucose stress test" (option A) and "non stress test" (option B). At 24 weeks with frank breech - ECV is not recommended before 36-37 weeks, LSCS is premature at 24 weeks for breech alone. At 24 weeks gestation, GDM screening with 75g OGTT (done at 24-28 weeks) is the appropriate next step during a routine antenatal visit. The answer is A - 75g oral glucose stress test (OGTT/GDM screening), as this is a routine 24-week visit action.

Q38. NOT considered a factor for high-risk pregnancy: Answer: C - Anaemia (trick question - actually anaemia IS a high-risk factor)
Wait - re-reading: all of obesity, polyhydramnios, anaemia, and previous caesarean section are risk factors. However, in Dutta's classification of high-risk pregnancy, anaemia (mild-moderate) is a risk factor but may be considered a lower-tier risk. The intended answer may vary, but in most Indian textbooks, all four are high-risk factors. If forced to choose, some editions list anaemia as a common condition that is managed rather than a "high-risk" marker per se. However, this is a poorly worded question - anaemia is actually a high-risk factor. The expected answer per some sources may be obesity is NOT always listed. This question is debatable; most sources would say none of the above are excluded, but the expected exam answer is likely C - Anaemia is NOT considered high risk (mild anaemia is very common and correctable), though this is controversial.

Q39. FALSE statement about fetal souffle: Answer: A - It is a sharp whistling murmur synchronous with the fetal heart sounds
FALSE - Fetal souffle (funic souffle) IS synchronous with the fetal heart, but it is actually due to blood flow through the umbilical arteries (not intervillous space).
Actually re-reading:
  • A: "synchronous with fetal heart sounds" - TRUE for funic souffle
  • B: "due to rush of blood through intervillous space" - this describes UTERINE souffle (synchronous with maternal pulse). Fetal souffle is due to blood through umbilical vessels.
  • C: "heard in 15% cases" - TRUE
  • D: "diagnostic of pregnancy when present" - TRUE
So the FALSE statement is B - it is NOT due to intervillous space blood flow; that is the uterine souffle. Fetal/funic souffle is due to blood rushing through the umbilical cord vessels.
Answer: B

Q40. Increased HCG NOT seen in: Answer: A - Ectopic pregnancy
HCG is increased in:
  • Hydatidiform mole (markedly elevated)
  • Trisomy 21 (Down syndrome) - increased in 2nd trimester screening
  • Multiple pregnancy
In ectopic pregnancy, HCG levels are lower than expected for gestational age and rise more slowly (subnormal rise). So ectopic pregnancy does NOT show increased HCG compared to normal pregnancy.

GYNAECOLOGY - Fibroid / Adenomyosis

Q41. Initially, all fibroids are: Answer: A - Intramural
All leiomyomas begin as intramural fibroids. As they grow, they may become submucosal (growing toward the endometrial cavity) or subserous (growing toward the peritoneal surface). They start within the myometrium.

Q42. Diagnosis from specimen (55-year-old, AUB, hysterectomy): Answer: D - Adenomyosis
The classic gross appearance described would show a bulky uterus with trabeculated myometrium and small hemorrhagic foci/cysts on cut section - this is adenomyosis. (Note: Without seeing the actual image, adenomyosis is the classic answer for a 55-year-old with AUB and a hysterectomy specimen showing this pattern, especially if the uterus appears uniformly enlarged with a thick trabeculated wall.)

Q43. Best definition of adenomyosis: Answer: B - Endometrial tissue within the myometrium
Adenomyosis = presence of endometrial glands and stroma within the myometrium, >2.5 mm from the basalis layer, surrounded by hypertrophied smooth muscle.
  • Endometriosis on ovaries = endometrioma
  • On serosa/peritoneum = endometriosis

Q44. Age group most commonly affected by adenomyosis: Answer: C - Women between 30-50 years
Adenomyosis classically affects multiparous women aged 35-50 years (perimenopausal). It is rare in adolescents and generally regresses after menopause.

GYNAECOLOGY - Infertility & Ovarian Tumors

Q45. Infertility defined as failure to conceive after: Answer: B - 12 months
WHO definition: Infertility = failure to achieve a clinical pregnancy after 12 months of regular unprotected sexual intercourse. (6 months applies for women >35 years in some guidelines, but the standard definition is 12 months.)

Q46. Most common cause of female infertility: Answer: D - Ovulatory dysfunction
Globally, ovulatory dysfunction (anovulation/oligoovulation) accounts for approximately 25-40% of female infertility - the single most common cause. Tubal factor is second (~30%). Dutta's and most gynae texts cite ovulatory dysfunction as most common, though some Indian sources cite tubal factor. For this exam context (Dutta), ovulatory dysfunction is the answer.

Q47. NOT a risk factor for ovarian carcinoma: Answer: B - Use of oral contraceptive pills
OCPs are actually protective against ovarian cancer (reduce risk by ~50% with 5 years of use). Risk factors include: family history, BRCA-1/2 mutations, clomiphene use (prolonged/unmonitored), nulliparity, infertility, endometriosis.

Q48. Strategy to reduce hereditary ovarian cancer risk in BRCA-1/2 mutation carriers: Answer: D - Prophylactic oophorectomy (risk-reducing salpingo-oophorectomy)
Prophylactic bilateral salpingo-oophorectomy (RRSO) is the most effective strategy to reduce ovarian cancer risk in BRCA-1/2 mutation carriers (reduces risk by ~96%). OCP use provides partial protection but is not the primary recommendation. Screening with TVS and CA-125 has NOT been shown to reduce mortality.

Q49. Most common ovarian tumor in women under 20 years: Answer: B - Germ cell tumor
In women under 20 years (and in children), germ cell tumors are the most common ovarian tumors (dysgerminoma, teratoma, endodermal sinus tumor, etc.). Epithelial tumors predominate in older women (>40 years).

Q50. Brenner tumor of ovary belongs to which WHO category: Answer: A - Epithelial tumors
The Brenner tumor (transitional cell tumor) is classified under surface epithelial-stromal tumors (epithelial tumors) of the ovary in the WHO classification. It arises from the surface epithelium and resembles transitional (urothelial) epithelium.

Summary Answer Key

QAnswerKey Point
1BFothergill DOES preserve uterus/reproductive capacity (though fertility poor)
2CRectocele → posterior colporrhaphy
3CMcCall culdoplasty - obliterate spacious cul-de-sac
4ARing pessary for young postnatal woman
5CCardinal + uterosacral = Level 1 (DeLancey)
6DComplex hyperplasia with atypia (~28-29%)
7D28%
8C~1% for cystic glandular (simple) hyperplasia
9CPCOD → unopposed estrogen
10ASimple hysterectomy (postmenopausal + atypia)
11AEngagement-Descent-Flexion-IR-Extension-ER-Expulsion
12DTone of levator ani
13CInternal rotation followed by external rotation
14DFetal temperature not on partograph
15ARight of ACTION line (not alert line) = referral
16DObesity in first-degree relatives
17CTerbutaline (beta-agonist → hyperglycemia)
18C38 weeks (insulin-controlled GDM)
19DOligohydramnios (GDM causes POLYhydramnios)
20APolycythemia
21BAfter 20 weeks
22DSmoking is PROTECTIVE against PIH
23BProteinuria >5 g/day
24DACE inhibitors
25CDefective trophoblastic invasion
26BMaternal hypertension
27C<10th percentile
28BReversed end-diastolic flow in umbilical artery
29CGenetic abnormalities → symmetric FGR
30DUltrasound biometry
31DChromosome 1
32DLewis antigens (plasma antigens, not on fetal RBCs)
33A28 weeks
34DPostpartum hemorrhage
35A50 micrograms (<12 weeks)
36DBefore conception
37A75g OGTT (GDM screening at 24-28 weeks)
38CAnaemia (debatable; standard risk factor but intended answer)
39BFetal souffle = umbilical vessels, NOT intervillous space
40AEctopic pregnancy has LOW/subnormal HCG
41AAll fibroids start intramural
42DAdenomyosis
43BEndometrial tissue WITHIN myometrium
44C30-50 years
45B12 months
46DOvulatory dysfunction
47BOCPs are PROTECTIVE against ovarian cancer
48DProphylactic oophorectomy (RRSO)
49BGerm cell tumors (<20 years)
50ABrenner = epithelial tumor
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