Key idea
Cranial nerves do not supply the full body.
There are 12 pairs, and they mainly supply the head and neck. The important exception is the vagus nerve (CN X), which travels into the chest and abdomen to supply internal organs. The trunk and limbs are mainly supplied by 31 pairs of spinal nerves.
Gray's Anatomy for Students states that all cranial nerves innervate head or neck structures, except CN X, which also innervates thoracic and abdominal viscera. - Gray's Anatomy for Students, p. 986.
The 12 cranial nerves and what they supply
| No. | Nerve | Main type | Main structures/functions supplied |
|---|
| I | Olfactory | Sensory | Smell from nasal mucosa |
| II | Optic | Sensory | Vision from retina |
| III | Oculomotor | Motor + parasympathetic | Most eye muscles, raises upper eyelid, constricts pupil, focuses lens |
| IV | Trochlear | Motor | Superior oblique muscle of eye, helps look down when eye is turned inward |
| V | Trigeminal | Mixed | Sensation from face, scalp, cornea, nasal and oral cavities, teeth, anterior 2/3 of tongue for general sensation; motor to muscles of chewing |
| VI | Abducens | Motor | Lateral rectus muscle, moves eye outward |
| VII | Facial | Mixed + parasympathetic | Muscles of facial expression; taste from anterior 2/3 of tongue; tears; saliva from submandibular and sublingual glands |
| VIII | Vestibulocochlear | Sensory | Hearing and balance from inner ear |
| IX | Glossopharyngeal | Mixed + parasympathetic | Taste and sensation from posterior 1/3 of tongue; sensation from pharynx; motor to stylopharyngeus; salivation from parotid gland; carotid sinus/body sensation |
| X | Vagus | Mixed + parasympathetic | Pharynx and larynx, swallowing and voice; sensation from thoracic and abdominal organs; parasympathetic control of heart, lungs, and much of gastrointestinal tract |
| XI | Accessory | Motor | Sternocleidomastoid and trapezius muscles: head turning and shoulder elevation |
| XII | Hypoglossal | Motor | Most tongue muscles for speech, swallowing, and tongue movement |
How this relates to body regions
1. Head and face
Cranial nerves largely control:
- Smell: CN I
- Vision: CN II
- Eye movements: CN III, IV, VI
- Facial sensation and chewing: CN V
- Facial expression, taste, tears, and salivation: CN VII
- Hearing and balance: CN VIII
- Tongue, swallowing, speech, throat, and neck movement: CN IX, X, XI, XII
2. Neck
- CN IX and X help with swallowing.
- CN X controls many muscles of the pharynx and larynx, therefore voice and cough reflex.
- CN XI supplies sternocleidomastoid and trapezius.
- CN XII moves the tongue.
3. Chest
The vagus nerve (CN X) supplies parasympathetic and sensory fibers to:
- Heart: slows heart rate
- Lungs and bronchi: influences airway smooth muscle and secretions
- Esophagus: helps swallowing and movement of food toward stomach
It also carries sensory information from many thoracic organs to the brainstem.
4. Abdomen
Again, mainly CN X, the vagus nerve, supplies parasympathetic fibers to much of the gut:
- Stomach
- Liver and gallbladder
- Pancreas
- Small intestine
- Large intestine up to approximately the proximal two-thirds of the transverse colon
Effects include promoting digestion, gut movement, and glandular secretion. Vagal sensory fibers also carry non-painful information from thoracic and abdominal viscera. Medical Physiology notes that the vagus carries non-nociceptive afferent input from viscera of the thorax and abdomen.
5. Pelvis, lower limbs, upper limbs, and most trunk
These are not supplied by cranial nerves.
They are supplied mainly by spinal nerves:
- Cervical spinal nerves: neck, shoulders, arms, hands
- Thoracic spinal nerves: chest and abdominal wall
- Lumbar spinal nerves: lower back and much of lower limb
- Sacral spinal nerves: pelvis, perineum, and parts of lower limb
Parasympathetic supply to pelvic organs comes chiefly from S2-S4 pelvic splanchnic nerves, not from the vagus.
Important parasympathetic cranial nerves: 3, 7, 9, 10
A useful exam summary:
- CN III: pupil constriction and lens accommodation
- CN VII: lacrimal, submandibular, and sublingual glands
- CN IX: parotid gland
- CN X: heart, lungs, and abdominal digestive organs
Easy mnemonic
“Oh Oh Oh To Touch And Feel Very Good Velvet, AH”
- Olfactory
- Optic
- Oculomotor
- Trochlear
- Trigeminal
- Abducens
- Facial
- Vestibulocochlear
- Glossopharyngeal
- Vagus
- Accessory
- Hypoglossal
Bottom line: Cranial nerves chiefly serve the head and neck. CN X is the only cranial nerve with extensive supply below the neck, reaching chest and abdominal organs. The limbs and most of the trunk are supplied by spinal nerves.