I now have comprehensive, detailed surgical steps from Campbell's Operative Orthopaedics 2026. Let me now compile the full, clear, stepwise answer.
Total Knee Replacement (TKR) - Complete Stepwise Guide
Source: Campbell's Operative Orthopaedics, 15th Ed. 2026 (Chapter 8)
Overview of What TKR Involves
Total Knee Replacement (also called Total Knee Arthroplasty - TKA) removes the damaged surfaces of the distal femur, proximal tibia, and optionally the patella, replacing them with metal and plastic components that recreate a smooth, painless joint. The goal is:
- Eliminate pain
- Restore mechanical alignment (correct varus/valgus deformity)
- Restore range of motion
- Balance soft tissues so the joint is stable throughout the arc of motion
Pre-operative Planning
Before the patient enters the operating room, the surgeon must:
- Review long-standing (hip-to-ankle) radiographs to measure the mechanical and anatomic axes of the femur and tibia
- Determine the valgus correction angle (VCA) for the distal femoral cut - typically 5-7 degrees
- Identify deformity pattern (varus/valgus/flexion contracture)
- Template implant sizes
- Plan the ligament balancing strategy based on the deformity
Patient Positioning
- Patient placed supine on the operating table
- A lateral post or leg holder is placed at the thigh to stabilize the leg during surgery
- The leg is positioned to allow the knee to be flexed to 90 degrees (a foot rest or leg holder is used)
- A pneumatic tourniquet is applied to the proximal thigh (typically inflated to 250-300 mmHg) to create a bloodless field
Step 1: Skin Incision
The standard incision is an anterior midline (straight) skin incision.
Medial parapatellar retinacular approach - Campbell's Operative Orthopaedics, 15th Ed.
Key points:
- Incision is made with the knee in flexion so subcutaneous tissue falls medially and laterally, improving exposure
- Runs from approximately 5-8 cm above the superior pole of the patella, over the midline, to 3-4 cm below the tibial tuberosity
- If a previous scar exists, incorporate it - use the most lateral usable scar since blood supply to the anterior knee comes predominantly from the medial side
- Incision must be long enough to avoid excessive skin tension (skin necrosis risk)
- The infrapatellar branch of the saphenous nerve will almost always be divided - warn the patient preoperatively about lateral knee numbness
Step 2: Deep Approach (Arthrotomy)
Several approaches exist. The most common is:
A. Medial Parapatellar Approach (Standard - most common)
- Incise the retinaculum along the medial border of the quadriceps tendon, leaving a 3-4 mm cuff of tendon on the vastus medialis obliquus (VMO) for later re-attachment
- Continue the incision around the medial side of the patella
- Extend 3-4 cm onto the anteromedial tibia along the medial border of the patellar tendon
- Elevate the anteromedial capsule and deep MCL subperiosteally off the tibia to the posteromedial corner
- Extend the knee and evert the patella laterally (or subluxate it if eversion is difficult - in obese patients, develop the lateral subcutaneous flap first)
- Flex the knee to 90 degrees
Danger: Never put excessive tension on the patellar tendon attachment at the tibial tubercle. Avulsion of the patellar tendon is difficult to repair and can be a devastating complication.
B. Subvastus ("Southern") Approach
- Same anterior midline skin incision
- Retinacular incision goes below the VMO - the superficial fascia overlying VMO is incised and the entire extensor mechanism is mobilized posteriorly to the medial intermuscular septum
- VMO origin is lifted off the septum to ~10 cm proximal to the adductor tubercle
- Entire extensor mechanism is dislocated laterally as a unit without cutting it
- Advantage: Preserves extensor mechanism integrity, faster quadriceps recovery, better vascularity to patella, less need for lateral release
- Disadvantage: Limited exposure in obese patients or after previous knee surgery
C. Midvastus Approach
- Same skin incision
- VMO muscle is split in line with its fibers starting at the superomedial border of the patella, extending proximally toward the intermuscular septum
- A safe zone of 4.5 cm from the patella margin can be safely split
- Preserves the supreme genicular artery and quadriceps tendon
- Contraindicated in: obesity, previous tibial osteotomy, preoperative flexion <80 degrees
Step 3: Synovectomy and Joint Preparation
Once inside the joint:
- Remove the ACL (anterior cruciate ligament) - it is always sacrificed in TKA
- Remove the anterior horns of both menisci
- Remove osteophytes from around the femoral condyles, tibial plateau, and intercondylar notch - these cause soft tissue imbalance and component malposition if left
- If a PCL-substituting (posterior-stabilized) design is planned, remove the PCL now or later with the box cut
- Subluxate and externally rotate the tibia - relaxes the extensor mechanism and decreases risk of patellar tendon avulsion
- Excise the infrapatellar fat pad partially or completely to expose the lateral tibial plateau
- Place a levering retractor carefully adjacent to the lateral tibial plateau for exposure
Step 4: Tibial Cut
The proximal tibial cut is made first in most systems (though some systems do femur first).
Alignment
- The cut must be perpendicular to the mechanical axis of the tibia in the coronal plane
- A 3-5 degree posterior slope is given (matches the native tibial slope) to allow flexion
- Extramedullary (EM) alignment is preferred for the tibia - the alignment rod points to just medial to the center of the ankle (approximately 2 mm medial to the midpoint of the malleolar axis)
- Intramedullary alignment can also be used but carries a small risk of fat embolism
Amount of Bone Removed
- Usually 8-10 mm from the less-involved (normal) tibial plateau
- Deeper cuts may be needed if there is significant bone loss, but the tibial component should always rest on good cortical bone
Key Pitfall
Bone removed from the proximal tibia affects both the flexion and extension gaps equally - so if you need more space, this is where to remove more bone.
Step 5: Distal Femoral Cut
Alignment
- The cut is made perpendicular to the mechanical axis of the femur
- This requires applying a valgus angle of 5-7 degrees (the VCA) to the anatomic axis of the femur
- This angle is measured preoperatively from long-standing radiographs
- Intramedullary (IM) alignment is standard on the femoral side because landmarks are not palpable
- IM entry point is placed a few mm medial to midline, anterior to the PCL origin
Amount of Bone Removed
- Typically the same thickness as the distal femoral component being implanted (to maintain joint line level)
- For flexion contracture correction: additional 1-2 mm can be resected, but avoid elevating the joint line by more than 4 mm
- For PCL-substituting designs: add 2 mm extra to the distal cut to account for the increase in flexion gap when PCL is sacrificed
Step 6: Femoral Sizing and Rotation - Four-in-One Femoral Cuts
After the distal femoral cut, the femoral sizing guide is placed to determine the correct component size and to set the rotation of the femoral component.
Rotation Landmarks (4 reference methods)
| Reference | Description |
|---|
| Transepicondylar axis (TEA) | Line between medial and lateral femoral epicondyles - most reliable |
| AP (Whiteside's) axis | Line from the sulcus of the trochlea to the top of the intercondylar notch; posterior cut perpendicular to this |
| Posterior condyles | Make cut in 3 degrees of external rotation off the posterior condylar line (unreliable in valgus knees with hypoplastic lateral condyle) |
| Tibial cut surface | Parallel to the proximal tibial cut when in extension |
Why does rotation matter? Internal rotation of the femoral component causes lateral patellar tilt and patellofemoral instability. Excessive external rotation widens the medial flexion gap causing flexion instability.
The Four-in-One Cut Block
Once rotation and size are set, a single cutting block makes four simultaneous or sequential cuts:
- Anterior femoral cut - resects the anterior distal femoral cortex
- Posterior femoral cut - resects the posterior femoral condyles
- Anterior chamfer cut - transitions from the distal cut to the anterior cut
- Posterior chamfer cut - transitions from the distal cut to the posterior cut
These 5 surfaces (distal + 4 peripheral cuts) form the shaped bone that accepts the femoral component.
Step 7: Tibial Preparation
- The tibial template is placed on the tibial cut surface to select the appropriate size
- Size to match the tibial cortex while avoiding overhang (overhang causes pain) or underhang (underhang sacrifices stability)
- Rotational alignment of the tibial component is set - typically aligned to the medial one-third of the tibial tubercle or to the junction of the medial and middle thirds
- The keel slot is cut using a punch or saw to accommodate the tibial component's central keel/peg
- Correct rotation is critical - internal rotation of the tibial component lateralizes the tubercle, increases the Q-angle, and causes lateral patellar subluxation
Step 8: Patellar Preparation (If Resurfacing)
Not all surgeons resurface the patella routinely, but when done:
- The patella is held with a clamp and its thickness measured with calipers
- A flat resection is made to remove the articular surface (typically 8-10 mm depth)
- Residual patellar bone thickness should be at least 12-15 mm to avoid fracture risk
- The patellar component (a polyethylene button) is centered on the bone, but should be medialized to approximate the median eminence (not centered on the cut surface - centering forces the bone to track with a higher Q-angle)
- An overall patellar thickness (bone + implant) equal to original thickness is the goal - increasing it anteriorly causes instability or limited flexion
Step 9: Trial Reduction and Gap Balancing
Before cementing the final components, trial components are inserted to assess:
Checking the Gaps
Two gaps must be equal and rectangular:
| Gap | How to check | What it means |
|---|
| Extension gap | Full extension with spacer/tensioner | Must equal flexion gap for stability |
| Flexion gap | 90 degrees flexion with trial components | If larger than extension gap, knee will be loose in flexion |
A symmetric rectangular flexion = extension gap is the goal.
| Gap Problem | Cause | Fix |
|---|
| Flexion gap > extension gap | Too much posterior femoral resection; PCL too tight | Use smaller femoral component (anterior reference); adjust rotation; check PCL |
| Extension gap > flexion gap | Too much distal femoral resection; flexion contracture | Downsize tibial insert; check posterior capsule |
| Both gaps too small | Not enough bone removed | Remove more proximal tibia equally |
| Both gaps too large (lax) | Too much bone removed | Use thicker tibial polyethylene insert |
Soft Tissue Balancing in Varus Knee (most common deformity)
Medial structures are contracted. Release in sequence (stepwise - only release what is needed):
- Deep MCL off the tibia subperiosteally (already done during exposure)
- Posteromedial capsule
- Semimembranosus insertion
- Posterior oblique ligament
- Superficial MCL (if still tight)
- Pes anserinus (rarely needed)
Soft Tissue Balancing in Valgus Knee
Lateral structures are contracted. Release stepwise:
- Lateral capsule (posterolateral corner)
- Pie-crusting of the iliotibial band (ITB) - multiple small perforations rather than complete release
- Popliteus tendon - increases flexion gap laterally more than extension gap
- If still unbalanced: posterior capsule off lateral femoral condyle
- Lateral head of gastrocnemius
- As last resort: MCL advancement on medial side
"No-Thumb" Patellar Tracking Test
- With trial components in place and the knee taken through a full range of motion, the patella should track centrally in the trochlear groove without the surgeon holding it
- If it tracks laterally: consider lateral retinacular release, check femoral and tibial component rotation
Step 10: Cementation and Final Implantation
Cementation (most common)
- Irrigate and dry all bony cut surfaces meticulously - bone must be dry for cement to bond
- Mix polymethylmethacrylate (PMMA) bone cement to the appropriate consistency ("doughy" phase)
- Apply cement to the cut bone surfaces (not just the implant)
- Tibial component first - seat the tray firmly, ensuring correct rotation; remove cement squeeze-out with a curette
- Femoral component next - seat firmly using a femoral punch; remove excess cement, especially posteriorly
- Extend the knee with a trial spacer to confirm complete seating of the femoral component
- Cement the patellar component if used
- Retighten all components once cement has hardened
- Use a tibial spacer of adequate thickness to hold the knee in full extension during cement curing - too thin causes posterior liftoff
Key rule: Follow the specific instructions for the bone cement being used - small variations in technique directly affect long-term survivorship.
Cementless Fixation (alternative)
- Requires more accurate bone cuts - no cement to compensate for gaps
- Relies on intimate apposition (bone-prosthesis gaps >0.5 mm fill with fibrous tissue, not bone)
- Trial tray is tested by pressing the periphery - any movement = revise the surface
- Bone ingrowth is maximal around fixation screws and pegs; these are essential for initial stability
Final Polyethylene Insert
- After the metal components are cemented, the final polyethylene tibial insert is snapped/locked into the tibial tray
- Remove all bone and cement debris before inserting the poly - third-body wear is a long-term failure mechanism
Step 11: Wound Closure
- Release the tourniquet after implantation; pack with moist sponges
- Identify and cauterize bleeding geniculate arteries (medial and lateral)
- Suction drains are no longer routinely recommended - no difference in infection or hematoma rates; drained patients actually receive more blood transfusions
- Close the retinaculum/quadriceps mechanism with interrupted or continuous strong absorbable sutures - the medial parapatellar incision is closed layer by layer, restoring the VMO cuff
- Close subcutaneous tissue
- Close skin with staples or sutures
- Sterile dressing; compression bandage applied
Summary: The Surgical Sequence at a Glance
PATIENT SETUP
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1. Tourniquet inflation
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2. Anterior midline skin incision (knee in flexion)
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3. Medial parapatellar arthrotomy (or subvastus / midvastus)
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4. Patellar eversion; ACL excision; meniscectomy; osteophyte removal
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5. TIBIAL CUT → perpendicular to mechanical axis, 3-5° posterior slope
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6. DISTAL FEMORAL CUT → 5-7° valgus angle via IM alignment
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7. FEMORAL SIZING + ROTATION → TEA / Whiteside's axis reference; 3° ER off posterior condyles
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8. FOUR-IN-ONE FEMORAL CUTS (anterior, posterior, chamfers)
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9. TIBIAL PREPARATION → size, rotation, keel slot
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10. PATELLAR RESURFACING (optional)
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11. TRIAL REDUCTION → check gaps, balance ligaments (varus = medial release; valgus = lateral release/pie-crust)
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12. PATELLAR TRACKING TEST ("no thumb" test)
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13. CEMENTATION → tibia first → femur → patella
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14. FINAL POLY INSERT
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15. TOURNIQUET DOWN → hemostasis
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16. LAYERED WOUND CLOSURE
Key Numbers to Remember
| Parameter | Value |
|---|
| Valgus correction angle (distal femoral cut) | 5-7 degrees |
| Posterior tibial slope | 3-5 degrees |
| Femoral rotation off posterior condyles | 3 degrees external rotation |
| Joint line elevation limit | No more than 4 mm |
| Residual patellar bone after resection | Minimum 12-15 mm |
| PCL: if >75% released, switch to PS design | >75% released = instability risk |
| Bone-prosthesis gap for ingrowth success | <0.5 mm |
Source: Campbell's Operative Orthopaedics, 15th Ed. 2026, Chapter 8 (Techniques 8.1-8.9)