In suspected myocardial infarction, Disprin (aspirin) should be chewed, not simply swallowed. Chewing a non-enteric-coated 300 mg aspirin speeds absorption. If it is a soluble/dispersible formulation, it may also be dissolved in water and drunk. Current emergency guidance commonly states “soluble or chewed.” ACS guidance

Do not take it if there is aspirin allergy, active/significant bleeding, or a clinician has told the person to avoid aspirin. Call emergency services immediately for suspected heart attack, rather than relying on aspirin alone.