5 month tb patient back pain happen and now vomiting 2 times and weakness also what to give

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tuberculosis treatment adverse effects

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WHO tuberculosis treatment nausea vomiting jaundice urgent adverse effects patient information

This needs same-day medical assessment, preferably at the TB clinic or emergency department. Vomiting and weakness after 5 months of TB treatment can be a medicine side effect, including liver injury, dehydration, electrolyte problems, or another illness. New back pain also needs assessment for possible spinal involvement, especially if severe or persistent.
Go to emergency now if any of these are present:
  • Yellow eyes/skin, dark brown urine, pale stools
  • Severe abdominal pain, fever, confusion, fainting, unable to drink or keep fluids down
  • Severe/worsening back pain, leg weakness/numbness, difficulty walking, loss of urine/stool control
Until assessed:
  • Contact the TB doctor/clinic today before taking further TB tablets. Do not permanently stop or restart TB medicines without their instruction, because the regimen may need urgent adjustment.
  • Give small frequent sips of ORS or water if they can keep fluids down.
  • Avoid alcohol and avoid self-starting painkillers or anti-vomiting drugs, particularly medicines containing paracetamol/acetaminophen, until liver problems are ruled out.
  • Take the TB medication packet and all other medicines to the visit.
TB drugs such as isoniazid, rifampicin/rifampin, and pyrazinamide can cause liver toxicity, where nausea, vomiting, poor appetite, fatigue/weakness, abdominal pain, dark urine, or jaundice are warning symptoms. The CDC adverse-effects guidance advises urgent reporting and clinical testing when these occur. They will likely check liver function tests, bilirubin, kidney function/electrolytes, and examine the back and nerves.

Pantop ondem given what to add for back pain happen

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CDC TB treatment adverse events nausea vomiting weakness back pain liver toxicity

Do not add a strong painkiller on your own. With vomiting and weakness during TB treatment, first rule out TB-drug liver toxicity or dehydration. Pantop (pantoprazole) and Ondem (ondansetron) may reduce symptoms but do not treat the cause.
For the back pain:
  • Use a warm compress, rest from lifting, and gentle position changes.
  • Avoid ibuprofen, diclofenac, naproxen, aceclofenac, and avoid adding paracetamol/acetaminophen until a clinician checks liver function, because vomiting/weakness with TB medicines can indicate liver injury.
  • Arrange examination today at the TB clinic/doctor. They need to review all TB medicines and check liver tests, bilirubin, electrolytes, and whether the back pain could be spinal TB or nerve compression.
Emergency immediately if pain is severe, fever, leg weakness/numbness, difficulty walking, urine/stool control problem, jaundice, dark urine, abdominal pain, repeated vomiting, or inability to drink.
CDC lists nausea, vomiting, fatigue/weakness, dark urine, and jaundice as potential serious liver toxicity from TB drugs such as isoniazid, rifampicin, and pyrazinamide in its TB adverse-effects guidance.
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