Long answer question (15marks) 1. Write a detail note on urea cycle with reaction? Mention its major metablic disorders . 2. Explain the transamination reaction ? Involved in the catabolism of amino acids. 3. What are the bile pigments. Name the diseases aassociated with their metablism. 4. What are transaminase. Write the fiagnostic importance of transaminases. 5. What are porphyrin. Explain the type and clinical importance of porphyria. Short answer question ( 5 marks) 1. Explain the transamination reaction involved in thr catabolism of amino avids. 2. Explain phenoketoneumia and alkaptoneumia 3. What is porphyria? 4. What is jaundice? Explain the different types of jaundice? 5. What is normal blood urea level? Name two condition in which blood urea level is elevated . Answer with high yield marks and for university level checker give extra marks impressive format in easy language try to have same basic concepts and simple words through which examiner can easily understand what's written. As long qyestion for 15 marks answer and short question for 5 marks answer

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Long answer question ( 15 marks ) 1. Describe the denovo - synthesis of purine nucleotides. 2. Explain the metabolic pathway for tge biosynthesis of pyrimidine nucleotides 3. Explain the detail the semi- conservation replication of double standard DNA molecules. Add a note on its repair mechanism. 4. Explain in detail about biosynthesis of proteins? 5. Define mutation ? Explain various types of mutation. Short answer ( 5 marks ) 1. Describe the different DNA repair mechanism? 2. Define genetic code and describe its characterstic feature? 3. What is leading and lagging strands of DNA . 4. Explain the nucleotides? Givr the name of 4 nucleotides. 5. What is onion peel model of DNA replication . Briefly explain. 6. What are okazaki fragments? What is gout? Answer with high yield marks and for university level checker give extra marks impressive format in easy language try to have same basic concepts and simple words through which examiner can easily understand what's written which includes flowcharts, picture in understanble language

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