hello students I'm the OG Dr punit Bjani here with a single point agenda to make OBGY your most favorite subject most scoring subject now very important video coming up many students were requesting me that sir oncology we find very tough oncology and specifically cervical cancer endometal cancer ovarian cancer so here's me presenting the top 10 oncology MCQs for the upcoming NEP 2026 feel free to get in touch with me on phone and WhatsApp on this number and happy to announce the live RR starting from 21st of July there going to be 10 sessions i'm going to cover everything more about this later on only in 8.99 rupees and the recordings will be available till the date of your August exam download the Oji Guru app and WhatsApp me on this number if you have any doubts more about this later on 10 live sessions and OBJ will become your most scoring subject most favorite subject now let us begin the MCQs so this is all the types of MCQs are there in this video by all the types I mean the new pattern like as you can see over here match the column multiple correct and there are images very important stay right till the very end in the end of the video towards the end I'm going to discuss three very important images also which are likely uh to be coming in this upcoming neat PG examination now match the column now why I like this match the column kind of question because indirectly they are asking us five MCQs five separate MCQs are being asked because here are the five different tumors and match the column with the following tumor markers okay now epithelial ovarian tumor all of us No CA1 125 is the tumor marker isn't it so E5 so when you see E5 E5 so automatically two options are gone two options are gone that's how you solve math column okay now I'll tell more about this C125 in some time corarcinoma beta HCG is the tumor marker for choreocarcinoma disger LDH okay please comment in the chat box for dgererman there's one more tumor marker diserinoma LDH is the tumor marker but there's one more also for digeloma so A1 A1 and we already have our answer yolk sack tumor also called as endodermal sinus tumor alpha phtoroin B3 C4 granlosa cell tumor inhibin and D2 as I already told you beta HCG for corocarcinomine E5 so very very important five-star slide coming up fivestar slide why I call it as five star because multiple questions can come as I said endodmal sinus tumor or yolk sack tumor alpha fto protein tumor marker epithelial tumor CA125 disgeroma LDH and one more which I was asking you alkaline phosphodus can also be in the exam and granular cell tumor inhibin also comment by the way this is gynecology but also comment in obstetrics in obstetics where is inhibin used obstetics which test we use in OBS patient pregnant lady which test we use in even please comment in the chat box now please understand this so the answer is our option number A a1 B3 C4 D2 E5 option number A is the answer okay now very very important two further things ca 125 is it specific for epiurin cancer no it is not at all specific it is not nonspecific so please comment in the chat box which gynac conditions CA125 is elevated it is not specific means many other conditions also other than epithelial tumor CA125 can be elevated please comment in the chat box two three important conditions in gynecology where CA125 is elevated yes colon cancer pancreatic cancer all that is there and I'm going to give you a trick what is the trick clap if you feel happy sir any abdominal organ you take any abdominal organ of your choice you take and P I add I T I S then CA 125 will be elevated means what am I saying pancreas pancreatitis gastric gastritis hippatitis colitis appendix appendicitis peronium peronitis tootalic salpingo spingitispitis fallopian tube salpitis okay so any abdominal organ we take plus the inflammation itis there the CA125 is going to be elevated pancreatitis colitis appendicitis all this is there and please you will also comment which are the other two three very important conditions in gynecology where CA125 is elevated okay now one more thing one more thing very famous you get in the pathology the hisystopath hisystopath bodies okay hystopath bodies okay this is again a pathology I'm see but I'm teaching you anybody for epithelial ovarian tumor we get samomaoma bodies and please comment in the chat box droid will see a tooth bone hair and the rocket transcriptto please comment granulosa cell tumor what is the body seen okay and in endodermal sinus tumor what is the body seen please comment I'm giving you a clue clue yeah the second letter okay so grandos cell tumor body starts with letter C please comment in the chat box an endodermal sinus tumor body on hystopath starts with letter S very important i'll give you the answer in chat box please comment so this is the trick clap if you feel happy okay so a CA25 trick I told you multiple conditions with which CA125 is elevated and for his bodies again it's a very famous MCQ it's of course MCQ in pathology and the granlosa cell tumor the name of the body starts with letter C endodermal sinus tumor here second letter is S so the letter starts with letter S please comment in the chat box so very important table and here lots of questions are expected you can also get the clinical question they can give you ulta that say this is a condition this tumor marker is elevated what is the tumor which the patient is having okay now moving on again now see this multiple now the problem is when the students get the question they directly start marking from here no please understand this till here is the MCQ till here is the MCQ and then your options are starting so longest question long stem and students panic okay nothing to worry okay so please a 55 year old lady complains with postmenopausal bleeding okay and was diagnosed with adininoarcinoma of the endometrium so basically CA endometrium CA endometrium is our question and all of the following are either the risk factors or the presenting factor for the same which of them okay so nully paras only estrogen all them okay so again clap if you feel happy I am going to tell you one I think it is a estrogen dependent tumor e Erogen is going to be the eeology estrogen ethology clap and PP progesterone is going to be protective isn't it so clap if you feel happy the trick to be kept in mind is E Euprogen will be the ethiology and PP progesterone is going to be protective okay that is the first trick so please keep in mind that if we give only estro that's why you never give only estrogen so if unopposed estrogenic action basically unopposed estrogenic action unopposed estrogen and therefore chronic anovvulation nullly paris patients only estrogen in the HRT early menarchi late menopause all these okay again remember the age group age group is mainly seen in post-menopausal 50 60 70 years okay so these are all the risk factors and can you tell me why diabetes and hypertension also is a very important risk factor and predisposing factor why because what is clap if you feel happy virgin MCQ corpus cancer syndrome what is corpus cancer syndrome anybody yes sir it's a triad of obesity hypertension and diabetes I repeat obesity hypertension diabetes associated with CA endometrium is called as corpus cancer syndrome surely this MCQ is coming in the exam so therefore automatically diabetes and hypertension also become the risk factor yes prolong use of DMPA dmpa is progesterone and progesterone as I told you is protective what else could be protective yes our OC pills okay OC pills LNG IUD myina P O D all are protective okay so oipels pregnancy multiparity myina pop all are protective so basically fourth is protective so four should not come four and four this is out this is out only 1 and three no 1 2 3 all 1 2 and three except four 1 and 3 9 only 1 and 3 9 two is important only estrogen hrt is very important if you give only estrogen it is unapos therefore for HRT we always prefer to give E plus V okay so 1 2 and three and that becomes the answer 1 2 and three that is it okay if the of course uterus has been removed then there is no risk of uh endometal cancer then only on those patients you give only estrogen HR for HRT always you give E plus P okay so these are risk factors protective factors I told you OCI pills pop myina that is the same is same as our LNG intrautrine device pop all that are protective for CA endometrium do not forget this corpus cancer syndrome one this virgin MCQ surely coming and one more virgin MCQ please comment in the chat box tough MCQ far MCQ simpsons pain what is this simpsons pain and Simpsons pain is seen in which condition please comment in the chat box okay simpsons pain simpsons pain is it seen in fibroid endometriosis cervical cancer endometal cancer simpsons pain is in which condition okay and corpus cancer syndrome do not forget very very important corpus cancer syndrome it's a triad of obesity hypertension diabetes associated with CA endometrium so moving on to the next MCQ again a longest clinical questions okay 48 year old paratri living very good presents to oped with heavy menstrual bleeding heavy menstrual h that is menorasia pelvic scan is okay no pathology office endometral biopsy or aspiration is done why always keep this rule in mind okay sir whenever I have got a permenopausal patient whenever I have a permenopausal patient hysystopathological examination of the endometrium is mandatory can you tell me why why mandatory why compulsory I should do hisystopath yes because sir any patient who is postmenopausal I have to rule out okay we need to rule out we read to rule out endometrial hyperplasia and endometrial cancer first is this understood before proceeding for the actual management which age group perry menopausal okay so any patient who is permenopausal with heavy menstrual bleeding or even post-menopausal bleeding hytopath examination is compulsory mandatory please keep this in mind and this was done office endometral aspiration management same thing endometral biopsy shows endometrial hyperplasia but with ertipia oh my godipia so what is the most appropriate management and moment the student seesia directly verdyctomy yes one of the most favorite wordctomy wrong clean bold okay sub students only know anything in cancer verdimetomy verdimetomy is another name for modified radical hyerectomy modified radical hyerectomy and that is not the answer over here why because please understand this that so students will whenever directly verdctomy but please understand verderectomy or modified radical hyerectomy is for actual cancer this is not cancer this is endometrial hyperplasia withpia so please understand this and specifically in a permenopausal patient and family is complete okay obviously estrogen is a risk factor we don't give estrogen estrogen will cause hyperplasia and cancer more okay and similarly in a perry menopause we avoid giving oipils also so what is the take-home message yes the take-home message is that yes sir simple hyperlas I'll tell you the numbers also simple hyperplasia or complex hyperplasia is given the question with otypia when they say even ifia is present whetheria is there or not if it's a permenopausal woman please understand this simple hyerectomy is more than enough what is the meaning of simple hyerectomy s simple hyctomy is not simple to perform okay simple hyerectomy means my dear student whatever again the root is not important I can do it abdominal vaginal laparoscopic whichever route I operate only the uterus and the cervix comes out that mean there's no need to remove the parametrium lymph nodes tubes ovary all that I don't have to remove so simple hyrectomy is the one which I basically do for any other benign condition okay so what hyerectomy I will do withia yes even ifia is present The hyerectomy is like like any other benign condition is this understood clap if you learned something new so sir even if a TPI is present it is not yet cancer it can become into cancer and therefore only a simple hyerectomy which I do for any other benign condition like a fibroid or a prolapse or a menorasia is more than enough so two important rules per menopausal hytopath has to be done your hytopath was done and endometrial hyperplasia with a TPI so simple hyctomy is more than enough and Verdam's hyerectomy not required to be done it's like a overkill okay if you have a fly you don't shoot a gun or a rifle okay so don't do over surgery don't do overkill okay so verdamsctomy you don't required a modified radicalctomy or verdams in this case which is only hyperplasia okay also please come in if it's a young patient what do I do it's a young patient so again a fivestar slide please by heart this numbers 13829 in the middle of the night if somebody wakes you up you should know this numbers 13829 even if you remember 30 for me is okay 13830 so simple hyperplasia 1% chance of cancer complex hyperplasia 3% the simple and complex is under the microscope okay please understand this hyperplasia is my hys histoopath diagnosis histoological examination of the endometrum and simple withpr which is was this case 8% and even if it's complex withpr maximum 30% chance of progression to cancer but it is not yet cancer it can become cancer so please understand this even in this case if simple word is replaced by complex okay if it's a what if it's a complex hyperplasia also with a TPR no problem answer is still simple hyerectomy verdam hyerectomy or modified radical hyerectomy is not required because this is a premalignant condition it can become cancer but it is not yet cancer and if the hyerectomy is like any other benign condition what we call it as a simple hyerectomy where only the uterus and the cervix comes out is this understood so again a very important table please by these numbers are important 13830 it could be asked to you or just keep in mind this concept moving on to the next very important again a 55 year old lady outpatient department post-menopausal bleeding for 3 months and when I do a perp speculum examination 1 into 1 cm nodule on the lip of the cervix what is the most appropriate investigation to be done now directly student anything to do with cervix they will say papsmear and again wrong why wrong because please understand this papsmear is a screening test and this papsmear time is gone so when I have a routine patient please comment in the chat box please comment in the chat box the papsmear is to be done for what age group what is the age group which I do the papsmear test papsme smear test should have been done for this lady many years ago okay now here please understand this so routine patient comes to the OPD of course I do a papsmear as a screening test also please comment what is the best if cost is not cost is not a problem tell please comment what is the best screening test what is best available something new today with pap I'll show you about this also later on the image based question also I'll be I'm going to show you okay so stay right till the very end so papsmear first age group you tell me why sir papsmear is not the answer because sir papsmear is a routine screening test we do it when the cervix is normal looking and we do a papsmear test here please understand this and why I don't do colossopy sir when the papsmear is abnormal okay when the papsmear is abnormal if the papsmear shows dysplasia or papsmear is abnormal then I perform a cervical biopsy and that is preferably culposcopic guided colossopy plus biopsy colosscopy is just a instrument it gives us magnification we can apply the acetic acid and with acid to white area whichever we see we can go and do a cervical biopsy so if the MCQ is okay a patient has come to the OPD and the papsmear is showing abnormality then I will do a cervical biopsy culposcopic guided okaycopy just gives you an idea so culposcopic guided cervical biopsy can be done but here please understand what is the scenario so here the scenario is that we are seeing a 1 by 1 cm on the anterior lip we are seeing a nodular growth or in another MCQ they can give you a fungating cauliflower like growth okay both same fungating growth any growth on the they can tell there's a fungating cauliflower like growth okay or a nodular growth as it is over here so whenever it is a growth which I can see the growth I will directly want to take a piece of it which is called as punch biopsy is this understood to all of you please comment therapeutic cone biopsies for which condition therapeutic is to treat so therapeutic cone biopsy and for which condition please comment in the chat box so culposcopy is to be done when the pap is abnormal paps smear is a screening test it's not important it's not possible it's not to be done over here because directly I am seeing a fungating growth is it clear because obviously sir when I can see the growth I will take a piece of this growth is it clear and that is called as a punch biopsy so whatever it is you take a piece of it which is called as a punch biopsy you take a punch of it okay so colosscopy is done only when the pap is abnormal colosscopy gives you magnification what filter to use in coloscopy all that coming up picture okay is it understood all of you so I repeat the flowchart that sir when the papsmear is abnormal we do a cervical biopsy preferably culposcopic guided that is 1 MCQ and when I see a obvious fungating growth fungating growth or a nodular growth given on the lips of the cervix then I do a punch biopsy you take a piece of that growth is this understood to all of you so punch biopsy is the answer to this very important MC CQ don't make a mistake therapeutic conbiopsy please comment in the chat box it is a therapy it is a treatment for which stage of cervical cancer which early stage of cervical cancer we can just get away by doing a therapeutic conbiopsy specifically in the young patient okay so papsmear is a screening test please comment what is the age group for the papsmear and what is the best what is the best screening test what is the best screening test available today and that is something more pap I'll tell you about it pap and I'll be send something more we do and what's the name of that test okay so PAP abnormal culposcopic added cervical biopsy obvious fungating growth nodular growth whatever growth if you are seeing nodular growth we go and do a punch biopsy is this understood yes now see this so as I told you papsmear a 30-year-old Paris patient came papsmear was showing abnormality so what do we do yes sir caloscopy and biopsy and now it is CIN3 what is the next line of management okay now again when I say students say CN lot of confusion is CIN cancer what is CN3 so please don't confuse C3 and CA cervix stage three same or different anybody CIN3 CAVIC stage three same right same or different completely different so please don't make a mistake this is not CI3 is not it looks very basic but in the heat of the exam students you made a mistake okay oh sir MCQ was cervical cancer stage three i thought CIN3 or CIN3 I thought CAVIC stage three okay because so many years of teaching I know where students make a mistake so CIN3 is not CAVIC stage three is this understood to all of you it is not both are different what is the difference also i will tell you in sometime and what do we do so if in a null paris patient and in a 30 year old if I remove the uterus I have to go to jail j jail it's a big crime you're not required again again it's not required to be done over here is it clear to all of you so you don't do it please don't do it jail M it's a big crime okay is it clear to all of you now CIN1 and two repeat papsmear and culposcopy can be done if it was only CIN1 or CIN2 because Cin 1 and two we can just do a followup but here it is CI3 now please understand this first of all we should also know what is the meaning of CIN so in CIN please understand this again the CI N is the diagnosis under the microsso in all of them the basement membrane is intact yes answer C N1 lower one/ird cells are filled with abnormal cell is again the pathology c2 lower 2/3 cells are abnormal or filled with abnormal cell cin3 they say almost the entire thickness filled with abnormal cell and carcinoma in C2 the whole thickness is filled with abnormal cell is understood so this again my dear student is your hisystopath diagnosis by looking at the patient in the OPD perspectulum don't comment so this is CN12 is it clear on per speculum I cannot make the diagnosis this is hisystopath pathologist will tell you now please understand this the basement membrane is intact act only if the basement membrane ruptures then there is cancer so just a progression which all of you should know i know all of you know but just to tell you okay why this is not difference please understand this sir first the patient may develop CIN1 then she might develop CIN2 then it will progress to CIN3 then carcinoma in C2 till here the basement membrane is intact and when the basement membrane is ruptured then you get yes then the cervical cancer starts then the cervical cancer starts and then it will Stage one stage two stage three stage four of cervical cancer is this understood to all of you so do not make a mistake this is simple but in the heat of pressure exam pressure and tension basement membrane is intact in CIN so you just up C3 and CAVIC stage three both are different even the management is complete the poles apart different so here the basement membrane is intact in CI now sir whenever I am giving you a mantra is sir whenever I have a patient who is C I N3 and is specifically a young patient she wants to preserve the uterus for further childbearing then there is no need to remove the uterusum is not required okay I told you you don't repeat pap and this also so two options are out what do we do yes sir we do a procedure called as leap or leads loop electroexyeng procedure l e p I repeat the full form loop electro there's a loop okay there is a loop and you pass a current in that loop there's a loop like this okay it's a loop like this and with this loop you pass current and you loop electroexision procedure also called as large loop excision of the transformation zone so we can declare the patient cure and then you can say okay go and have your babies go and have your babies so in a 30-year-old patient the answer is leap or leads why I do leap or leads large loop excision of the transformation zone and patient is declared cure uterus is preserved and she can have her own babies in the future so CI and three it's a young patient leap or leads both mean thesame thing leap leads mean the same thing loop electroexision procedure or large loop excision of the transformation zone is the treatment please keep this in mind it is not CAVIC stage three please comment for cervical cancer stage three what is the treatment cervical cancer stage three MCQ what is the treatment please comment in the chat box is it clear to all of you yes moving on to the next MCQ so young patient CIN3 leaps is the answer to preserve the uterus is it understood because it is not yet cancer it can become into cancer again it is not cancer it's a premalignant condition it can progress to cancer but it is not yet cancer and therefore I can preserve the uterus is this understood to all of you yes moving on to the next very important MCQ this is very very important MCQ now again the mistake which student make is what they don't read the question a routine patient comes to the OPD routine cervical screening and papsmear shows abnormal cells or typical cells what do I do cervical biopsy yes sir just now only you told me right just now I told you yes sir when the papsmear is abnormal when the papsmear is showing dysplasia yeah any abnormality we do a cervical biopsy yes that is true but here please understand one word one word change the whole MCQ okay yes sir we are seeing atypical cells but we are seeing atypical glandular cells now glands yes so cervix is the squammer cell cancer isn't it the CA cervix the cervical cancer cervical cancer mainly we know is squamus cell cancer and yes as I told you this already if the pap is showing abnormality or dysplasia we do kulposcopic guided cervical biopsy so pap is abnormal but please understand this that in this papsmear it is a typical glandular cells so please understand this that the papsmear test if only it was papsmear shows a typical squammer cell or something then the answer would have been cervical biopsy and culposcopy okay if it is showing a typical squammer cells or whatever okay but here please understand this difference my dear student is that it is atypical glandular cells so papsmear by the way please understand papsmear is a screening test for cervical cancer but if the patient has CA endometrium in case in case if the patient has a CA endometrium of course hystopath is confirmation hystopath is confirmatory and this papsmear is only your expo cytologology papsmear remember is cytologology okay remember that papsmear is cytology a typical cells we are seeing okay so by chance if a patient patient has CA endometrium those endometrium cells can get exfoliated and can come in the posterior forex or in the cervical area and when we do the papsmear test it can pick up this so it's a incidental finding it's a incidental finding that the papsmear is showing atypical glandular cell it not supposed to show so sortical glandular cells glands yes adinocarcinoma ca endometrium so I have to when I have this typical glandular cells I have to think of CA endometrium are you getting my point endometrial cancer is what I'm supposed to think out and I need to rule out endometrium cancer is this understood to all of you rule out CA endometrium okay ca endometrium I need to rule out and therefore I will not only do cervical biopsy because it is a typical path i will also do endometrial biopsy do not directly jump to hyerectomy is it clear is it clear so I repeat cervical biopsy and culposcopy would have been the answer if only pap is showing they tell you pap is showing displasia or pap is showing abnormality or pap is showing displastic cells dysplasia or abnormal cervical cells okay cervical cells but here because glandular cell has come glandular word glands is CA endometrium i need to rule out CA endometrium also in this patient and therefore I will do yes cervical biopsy one more step endometrial biopsy combination so what is the advantage of this option C that sir with one investigation endocervical and endomet with one investigation I will be able to rule out or find out I will be able to find out whether patient has got cervical cancer also and CA endometrium also both the things with one shot because cervical biopsy if the patient has cervical cancer this will be detected early stages whatever CN 1 2 3 whatever and the patient has C endometrium Then this also we can find out is this clear with this endometal buffs so you have the answer so I repeat if only the pap is showing abnormal typical squammer cell or typical cells or premalignant cells then it is only restricted to cervix then the answer is calledoscopic cervical biopsy but here since specifically atypical glandular cells are seen I have to rule out endometrial endometrial hyperlasia rule out c endometrium yeah endometral hyperplasia i told it could be hyperplasia with otpia also okay so rule out endometral hyperplasia and endometal cancer that is possible only by doing endometral biopsy and therefore option C is the answer clap if you have learned the new concept okay moving on again a very very important tandem and avoid now when this question comes student clean so what is this please understand this tandem and avoid radiotherapy now all of you knowradiotherapy sir is of two types radiotherapy sir is either teley theapy from external beam external beam from far when I shoot the radiation that is teleotherapy and one is brachither theapy brachi therapy is going close to the organ and giving it radiation so this tandem and avoid radiotherapy is a part of brachi therapy we use for cervical cancer late stages it is three stage three stage for cervical cancer when it is there what is this tandem so please understand this it is a rod okay so this is the uterus this is the cervix okay so what is tandem tandem is a rod okay tandem is a rod and ovoid is like two ball like structure okay so tandem is a rod tandem is a rod and overid are two ball-l like structure it looks like this okay so what is done is this tandem rod is inserted into the uterus okay through the cervix and of course the ovoids will remain here like this and then it will be charged with radioisotopes the tandem and ovids are charged with radioisotopes and then they will give radiation to this cervical cancer stage three stage four is it clear advanced stage of cervical cancer where we use radiotherapy or CTRT concurrent chemo radiation okay cy platin can also be given and therefore we use the word CTRT concurrent chemo radiation so tandem and ovoid radiotherapy is for cervical cancer it's not for ovarian and endometal cancer and choreocaroma we completely treat with your medical management extremely cheosensitive endometrium cancer after surgery we give radiation ovarian cancer we have to mainly give chemotherapy okay so cervical cancer may I repeat we use bracki therapy and by that bracket therapy it is tandem and ovid tandem is a rod or is this is your tandem and this is ovoid os okay so tandem radio theapy pa tandem and ovoid pa is for cervical cancer when the patient has cervical cancer as a part of brackchither theapy please tell me the advantage what's the advantage of brachi therapy okay what's the advantage of brachi therapy please tell me also asked in the recent FMG examination brachi therapy why we give brachi therapy what's the advantage of giving brachi therapy okay so when we give brachi radiootherapy to a patient of cervical cancer there we use tandem and oid very very important MCQ and again remember image based questions baky please understand this picture but very quickly Please understand this 10 live sessions whichever source you have studied OBGY from as you know my dear student 20 to 25 MCQs 20 to 22 MCQs are going to come in OBGI and it will become your most scoring subject life-changing only in 8.99 we are going to give you 10 live sessions including the video based question also will be there and I am going to take IBQs images like this clinical case everything will be done PyQs of not only INIC need PGNIC everything will be covered live doubt solving and don't and a notes read along session also so download the OG guru app and I'll be seeing you live on 21st July and recordings will be available and all of you can see all these topics are there so 8.99 rupees 11 sessions recordings will be available till August exam my guarantee OBJ which will become your most favorite subject most scoring subject look at the list all this 100% i've been conducting this session since last so many years and we have got a 100% strike rate when you will walk out of the NEP PG exam you will message me and call me on this number that's among all 19 subject my best performance is in OBGY okay and if your current score is 10 11 12 13 MCQs just attend this 10 sessions if you cannot attend live recordings will be available till August exam don't worry okay just attend this 10 sessions and score in OBGY from 10 11 12 will difference between rank of 400 and 40,000 my dear student so all the topics infertility HSG hyrolaparaposcopy we can go this manora contraception fibroid prolapse oncology eurog gynecology everything we are going to cover tisomi 21 very important drugs labor malpresentation pph all the recent advances pacclamia clamsia all these topics etopic everything and a video based abortion so all these are the list of most important topics which are going to come in the npg and therefore there are 10 sessions starting from 21st of July only in 89 99 so many of you have already enrolled do not miss out on this opportunity and I'm going to see you live on 21st is this understood now moving ahead ibq imagebased question very very important but whenever a image is asked to you also try to look at the history what is there 60 year old patient so postmenopause again a obese patient for a post-menopausal bleeding she underwent a hyerectomy okay you can see uterus tube ovary all that removed and the cut section is shown to you pathology yes so see fibroids don't present with postmenopausal bleeding again adinomiiosis don't present with the postmenopausal bleeding once menopause aa they start shrinking the fibroids and all that adonomas is cured okay and endometriosis so everything is outside the uterus chocolate cyst and all that you see okay yes if you closely observe the cut section yes sir we are seeing a fungating growth in the cavity which is CA endometrium okay and remember just one more MCQ adino carcinoma is the most common variety so this is a very important TYQ likely to be repeated yes sir and again I told you yes obesity hypertension diabetes are risk factors for CA endometry could be given to you post-menopausal bleeding is the most common presenting feature but remember post-menopausal bleeding can happen in cervical cancer also so if the same MCQ if the same MCQ is there or the same image and if here nothing but here if you see a fungating growth here if you see a fungating growth it is your cervical cancer okay because early stage cervical cancer also we do a we do this hyerectomy okay modified radical overtimes 1 A 2 1 B 2 A okay so see the image

Here's a structured summary of the key OBGY oncology points covered in this lecture by Dr. Punit Bajaj:

OBGY Oncology - Top MCQ Points (NEE/NEET-PG 2026)


1. Tumor Markers - Match the Column

TumorMarker
Epithelial ovarian tumorCA-125
ChoriocarcinomaBeta-hCG
DysgerminomaLDH + Alkaline Phosphatase
Yolk sac tumor (Endodermal sinus tumor)Alpha-fetoprotein (AFP)
Granulosa cell tumorInhibin
CA-125 is NOT specific - elevated in any "-itis" of an abdominal organ (pancreatitis, colitis, appendicitis, salpingitis, peritonitis, hepatitis, etc.)
Histopathological bodies:
  • Epithelial ovarian tumor: Psammoma bodies
  • Granulosa cell tumor: Call-Exner bodies (starts with "C")
  • Endodermal sinus tumor: Schiller-Duval bodies (starts with "S")

2. CA Endometrium (Endometrial Cancer)

Risk factors (Unopposed Estrogen):
  • Nulliparity
  • Only estrogen HRT
  • Chronic anovulation
  • Early menarche / Late menopause
  • Obesity, Hypertension, Diabetes
Corpus Cancer Syndrome = Triad of Obesity + Hypertension + Diabetes associated with CA endometrium
Protective factors:
  • OC pills
  • Progesterone / DMPA
  • LNG-IUD (Mirena)
  • POP (Progestogen-only pill)
  • Multiparity
HRT rule: Always give Estrogen + Progesterone (never unopposed estrogen unless uterus is removed)

3. Endometrial Hyperplasia - Risk of Progression to Cancer

TypeRisk
Simple hyperplasia~1%
Complex hyperplasia~3%
Simple hyperplasia with atypia~8%
Complex hyperplasia with atypia~29-30%
Management of endometrial hyperplasia with atypia in perimenopausal woman:
  • Simple hysterectomy (NOT Wertheim's/modified radical hysterectomy)
  • Wertheim's = only for actual cancer, not premalignant conditions
Key rule: Perimenopausal patient with heavy menstrual bleeding → histopathological examination of endometrium is mandatory (to rule out hyperplasia and cancer)

4. Cervical Cancer - Investigation Algorithm

Routine screening → Pap smear (cytology)
         ↓
Pap smear ABNORMAL → Colposcopy + Cervical biopsy
         ↓
Obvious fungating/nodular growth VISIBLE → Punch biopsy (directly)
Pap smear shows Atypical Glandular Cells (AGC):
  • Think CA endometrium (glandular = endometrium)
  • Do: Cervical biopsy + Endometrial biopsy (to rule out both)

5. CIN vs Cervical Cancer Stage - KEY DISTINCTION

FeatureCIN 1/2/3Cervical Cancer
Basement membraneIntactRuptured
NaturePremalignantMalignant
  • CIN 1 & 2: Repeat Pap + colposcopy (follow-up)
  • CIN 3 (young patient): LEEP / LLETZ (Loop Electrosurgical Excision Procedure / Large Loop Excision of Transformation Zone) - preserves uterus
  • Carcinoma in situ: Basement membrane still intact, whole thickness abnormal
Do NOT do hysterectomy for CIN 3 in a young nulliparous patient!

6. Tandem and Ovoid Radiotherapy

  • Used in cervical cancer (advanced - Stage 3/4)
  • Type: Brachytherapy (radiation source placed close to tumor)
  • Tandem = rod inserted into uterus
  • Ovoid = two ball-like structures placed in vaginal fornices
  • Often combined with cisplatin = CTRT (Concurrent ChemoRadiotherapy)
Advantage of brachytherapy: High local dose to tumor with less radiation to surrounding normal tissues

7. Postmenopausal Bleeding - Image-Based

  • Cut section showing fungating growth in uterine cavity = CA Endometrium (adenocarcinoma - most common variety)
  • Fungating growth on cervix = Cervical cancer
  • Fibroids and adenomyosis do NOT present with postmenopausal bleeding (they regress after menopause)

8. Quick Recall - Cancer Management Summary

CancerPrimary Treatment
Cervical cancer (early)Surgery (Wertheim's hysterectomy)
Cervical cancer (advanced)CTRT (Chemo + Radiotherapy)
Endometrial cancerSurgery + Radiotherapy
Ovarian cancerSurgery + Chemotherapy
ChoriocarcinomaChemotherapy (highly chemosensitive)

These are high-yield, exam-ready points covering the core concepts from the lecture. Focus especially on Corpus Cancer Syndrome, the CIN vs CA Cervix Stage 3 distinction, LEEP for CIN 3, and the tandem-and-ovoid brachytherapy question - these are flagged as near-certain NEE-PG 2026 MCQs.
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