Bph patho gross
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"prostatic hyperplasia"[MeSH Terms]
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benign prostatic hyperplasia gross pathology nodular periurethral transition zone
Finding Sources
Finding Sources
Reading File
BPH - Gross pathology
- Site: Arises in the periurethral and transition zone of the prostate.
- Size/weight: Prostate is enlarged, often 3 to 5 times normal size, commonly about 60-100 g.
- Cut surface: Shows multiple well-circumscribed nodules.
- Gland-predominant nodules: soft, yellow-pink; may express milky prostatic fluid.
- Fibromuscular stromal nodules: pale gray and firm.
- Urethral effect: Nodules compress and elongate the prostatic urethra, leaving a slit-like lumen. This causes bladder-outlet obstruction.
- A median periurethral nodule may project into the bladder neck, producing a median lobe.
- Severe longstanding obstruction may be associated with trabeculated bladder, diverticula, hydroureter, and hydronephrosis.
One-line exam answer:
BPH is a nodular enlargement of the periurethral transition zone, producing a 60-100 g prostate with soft yellow-pink glandular and firm gray stromal nodules that compress the prostatic urethra into a slit-like channel.
BPH is a nodular enlargement of the periurethral transition zone, producing a 60-100 g prostate with soft yellow-pink glandular and firm gray stromal nodules that compress the prostatic urethra into a slit-like channel.
Source: Robbins, Cotran & Kumar Pathologic Basis of Disease, morphology section, lines 1665-1669.
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