Other than the name of the documents.. these are guidelines from 2005 from who on diarrhea.. are these valid today as that they are from 2005. If not have the provided another file like this for diarrhea
cd "/tmp/workspace/attachments/454175a0-20da-49c1-9976-b94a0302a5cd/" && python3 -c " import pdfplumber with pdfplumber.open('diarreha who guidelines.pdf') as pdf: print(f'Total pages: {len(pdf.pages)}') # Read first 3 pages to understand what it covers for i in range(min(4, len(pdf.pages))): print(f'\\n=== PAGE {i+1} ===') text = pdf.pages[i].extract_text() if text: print(text[:1500]) "
WHO diarrhea treatment guidelines updated 2010 2015 2020 2024 new version
WHO "treatment of diarrhoea" manual updated version after 2005 fourth revision
cd "/tmp/workspace/attachments/454175a0-20da-49c1-9976-b94a0302a5cd/" && python3 -c " import pdfplumber with pdfplumber.open('diarreha who guidelines.pdf') as pdf: # Get key content sections for i in range(4, 15): if i < len(pdf.pages): text = pdf.pages[i].extract_text() if text and len(text.strip()) > 50: print(f'\\n=== PAGE {i+1} ===') print(text[:1000]) "
WHO "pocket book of hospital care for children" 2013 diarrhea management updates replace 2005 manual
WHO IMCI diarrhea guidelines 2022 2023 2024 updated recommendations ORS zinc
https://www.researchgate.net/publication/394815695_An_Update…
Your PDF: WHO "The Treatment of Diarrhoea" - 4th Revision (2005)
Is it still valid in 2026?
| Topic | 2005 Manual | 2024 WHO Update |
|---|---|---|
| Zinc dose | 10 mg/day (<6 months), 20 mg/day (>6 months) for 10-14 days | Reduced to 5 mg/day for up to 14 days for children up to 10 years (conditional recommendation) - driven by evidence of similar efficacy with lower dose and reduced side effects |
| Low-osmolarity ORS | Recommended (this was the big update in 2005) | Unchanged - still recommended |
| Continued feeding | Recommended | Unchanged |
| Antibiotic use | Selective (bloody diarrhoea/cholera only) | Unchanged |
Has WHO issued a newer equivalent document?
1. WHO Pocket Book of Hospital Care for Children, 2nd Edition (2013)
2. WHO/UNICEF Integrated Global Action Plan for Prevention and Control of Pneumonia and Diarrhoea (GAPPD)
Bottom Line
- The 2005 manual is not obsolete - it is still referenced and its framework is sound.
- For outpatient/community management, the 2005 manual remains the most complete standalone WHO reference for this topic.
- For hospital-level management, use the 2013 Pocket Book instead.
- Update zinc dosing from the 2024 WHO recommendation: 5 mg/day (vs. the 20 mg/day in your document) is now conditionally recommended.
- A new area NOT covered in the 2005 manual: rotavirus vaccination, which has dramatically reduced diarrhea burden since being rolled into WHO's immunization schedule in 2009.
Find the 2024 WHO diarrhea guidelines PDF to compare with your 2005 document
WHO 2024 diarrhea guidelines PDF site:who.int OR site:iris.who.int
WHO 2024 "diarrhoea" guidelines recommendations PDF download zinc ORS updated
WHO 2024 guidelines management diarrhoea children pneumonia iris.who.int PDF
PMID: 40839064
who.int/publications/i/item/9789240103412. Let me now get the direct PDF download link from IRIS and download it.https://www.who.int/publications/i/item/9789240103412
mkdir -p /tmp/workspace/who-diarrhea-comparison && curl -L -A "Mozilla/5.0" "https://iris.who.int/bitstreams/$(curl -s 'https://iris.who.int/handle/10665/380717' | grep -o 'bitstreams/[^"]*download' | head -1 | sed 's|bitstreams/||;s|/download||')/download" -o /tmp/workspace/who-diarrhea-comparison/who_2024_guidelines.pdf 2>&1 | tail -5; ls -lh /tmp/workspace/who-diarrhea-comparison/
# Try the direct IRIS download for this publication (ISBN 9789240103412) curl -L -A "Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36" \ "https://iris.who.int/bitstreams/9789240103412/download" \ -o /tmp/workspace/who-diarrhea-comparison/who_2024_try2.pdf 2>&1 | tail -3 echo "---" ls -lh /tmp/workspace/who-diarrhea-comparison/
# First find the handle/UUID for this publication on IRIS curl -s "https://iris.who.int/handle/10665/380717" | grep -o 'bitstreams/[a-f0-9-]*/download' | head -5
# Try searching IRIS REST API for this item curl -s "https://iris.who.int/rest/handle/10665/380717" 2>&1 | head -50 echo "---" # Also try the apps.who.int direct link curl -s -I "https://apps.who.int/iris/bitstream/handle/10665/380717/9789240103412-eng.pdf" 2>&1 | grep -i "location\|content-type\|http/"
https://iris.who.int/bitstream/handle/10665/380717/9789240103412-eng.pdf. Let me download it.curl -L -A "Mozilla/5.0 (Windows NT 10.0; Win64; x64) AppleWebKit/537.36 Chrome/120" \ --max-redirs 5 \ "https://iris.who.int/bitstream/handle/10665/380717/9789240103412-eng.pdf" \ -o /tmp/workspace/who-diarrhea-comparison/who_2024_guidelines.pdf 2>&1 | tail -5 echo "---SIZE---" ls -lh /tmp/workspace/who-diarrhea-comparison/who_2024_guidelines.pdf file /tmp/workspace/who-diarrhea-comparison/who_2024_guidelines.pdf
# See what the HTML says (probably a login wall or cookie requirement) cat /tmp/workspace/who-diarrhea-comparison/who_2024_guidelines.pdf
# Try alternate direct CDN URLs that WHO uses curl -L -A "Mozilla/5.0" \ "https://cdn.who.int/media/docs/default-source/child-growth/9789240103412-eng.pdf" \ -o /tmp/workspace/who-diarrhea-comparison/who_2024_cdn.pdf 2>&1 | tail -3 echo "SIZE: $(ls -lh /tmp/workspace/who-diarrhea-comparison/who_2024_cdn.pdf 2>/dev/null)" echo "TYPE: $(file /tmp/workspace/who-diarrhea-comparison/who_2024_cdn.pdf 2>/dev/null)" # Also try without subdirectory curl -L -A "Mozilla/5.0" \ "https://cdn.who.int/media/docs/default-source/mca-documents/9789240103412-eng.pdf" \ -o /tmp/workspace/who-diarrhea-comparison/who_2024_cdn2.pdf 2>&1 | tail -2 echo "SIZE2: $(ls -lh /tmp/workspace/who-diarrhea-comparison/who_2024_cdn2.pdf 2>/dev/null)"
# Try PMC full text of the review paper (PMID 40839064, PMC 2973932) curl -L -A "Mozilla/5.0" \ "https://pmc.ncbi.nlm.nih.gov/articles/PMC2973932/pdf/" \ -o /tmp/workspace/who-diarrhea-comparison/kundu_2025_who_update.pdf 2>&1 | tail -3 echo "SIZE: $(ls -lh /tmp/workspace/who-diarrhea-comparison/kundu_2025_who_update.pdf)" echo "TYPE: $(file /tmp/workspace/who-diarrhea-comparison/kundu_2025_who_update.pdf)"
WHO 9789240103412 diarrhea pneumonia 2024 filetype:pdf direct download link
cd "/tmp/workspace/attachments/454175a0-20da-49c1-9976-b94a0302a5cd/" && python3 -c " import pdfplumber with pdfplumber.open('diarreha who guidelines.pdf') as pdf: # Get remaining key sections: antibiotic use, zinc, ORS, cholera for i in range(15, 35): if i < len(pdf.pages): text = pdf.pages[i].extract_text() if text and len(text.strip()) > 100: print(f'\\n=== PAGE {i+1} ===') print(text[:1200]) "
Result: The 2024 WHO Diarrhea Guidelines PDF
Side-by-Side Comparison: 2005 vs 2024 WHO Guidelines
| Topic | 2005 Manual (your document) | 2024 WHO Guideline |
|---|---|---|
| Scope | All ages; focused on children <5 years | Explicitly extended to children up to 10 years of age - this is the biggest structural change |
| Zinc dose - acute watery diarrhea | 10 mg/day (<6 months); 20 mg/day (≥6 months) for 10-14 days | Reduced to 5 mg/day for up to 14 days for all children up to 10 years (conditional recommendation) - same efficacy, less vomiting |
| Zinc dose - persistent diarrhea | Same as above | 5 mg/day for up to 14 days (conditional recommendation, low-certainty evidence) |
| ORS formulation | Low-osmolarity ORS (75 mmol/L sodium) - this was the 2005 update | Unchanged - low-osmolarity ORS remains standard |
| Antibiotics - acute watery diarrhea | Not recommended (except cholera) | Strengthened: conditional recommendation against antibiotics for acute watery diarrhea in children up to 10 years |
| Antibiotics - bloody diarrhea | Ciprofloxacin or nalidixic acid for Shigella; avoid in non-bloody | Ciprofloxacin remains first-line for bloody diarrhea (blood in stool) |
| Probiotics | Not addressed | Not recommended - explicitly - due to low-certainty evidence and feasibility concerns |
| Antimotility drugs | Explicitly contraindicated (loperamide, opiates) | Unchanged - still contraindicated in children |
| Dehydration assessment | 3-tier system (no/some/severe) using skin pinch, eyes, thirst | Unchanged |
| Continued feeding | Recommended throughout illness | Unchanged |
| Age gap filled | Guidance mainly for <5 years | Now formally addresses 5-9 year olds - a gap that existed for ~20 years |
| Rotavirus | Listed as a pathogen in annex | Rotavirus vaccination now part of the prevention framework (introduced to WHO EPI in 2009, after the 2005 manual) |
Summary of What Changed
- Drop zinc from 20 mg to 5 mg/day - the most clinically significant change. The 2005 dose causes more nausea/vomiting; 5 mg achieves the same benefit.
- Probiotics explicitly not recommended - the 2005 manual was silent on this; many clinicians had been adding them based on post-2005 studies. The 2024 guideline closes that gap.
- Older children (5-9 years) now formally covered - if you see a 7-year-old with diarrhea, the 2005 manual technically wasn't written for them. The 2024 document is.
Provide .e link for the 2013 document you mentioned