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Burns in Surgical Practice
A burn is a traumatic injury to skin and underlying tissues caused by thermal, chemical, electrical, or radiation agents. Burns remain a major cause of morbidity and mortality globally. Surgical care has evolved dramatically since the introduction of early burn excision and structured fluid resuscitation protocols.
1. Aetiology / Classification by Cause
| Type | Examples |
|---|
| Thermal | Scalds (hot liquids/steam), flame, contact with hot objects, flash burns |
| Chemical | Acid, alkali (alkali penetrates deeper due to liquefactive necrosis) |
| Electrical | Low-voltage, high-voltage, lightning; causes "entry and exit" wounds with internal damage disproportionate to surface appearance |
| Radiation | UV exposure (corneal burns/keratitis), nuclear, X-ray |
| Friction | Road rash, machinery injuries |
Diathermy burns (surgical context): Monopolar diathermy can cause unintended burns when:
- The indifferent (return) electrode has inadequate contact area
- The patient is earthed via contact with metal (Mayo table, stirrups)
- Faulty insulation of leads
- Accidental activation or contact of the active electrode with retractors/towel clips
- Channelling - when current is applied to a narrow tissue stalk (e.g., risk of penile/spermatic cord coagulation during circumcision), bipolar diathermy must be used instead
Alcohol-based skin preparation agents can ignite from diathermy sparks under theatre lights, making these fires difficult to detect early. - Bailey and Love's Short Practice of Surgery 28th Ed, p.133
2. Burn Depth Classification
This is the single most important determinant of surgical decision-making.
Superficial (First-Degree)
- Involves epidermis only
- Erythematous, painful, no blistering
- Not included in TBSA% calculations
- Heals in days with supportive care
Superficial Partial-Thickness (Second-Degree)
- Involves papillary dermis
- Pink, moist, blistering, brisk capillary return (blanches)
- Normal pinprick sensation
- Heals in 2 weeks without surgery, no significant scarring
Deep Partial-Thickness (Deep Dermal)
- Involves reticular dermis
- Dermis less moist, less erythematous; fixed capillary staining; does not blanch
- Reduced sensation (cannot distinguish sharp from blunt)
- Takes >3 weeks to heal and invariably leads to hypertrophic scarring without surgery
Full-Thickness (Third-Degree)
- Destroys entire dermis; leathery, insensate, white/brown/black
- No spontaneous healing - requires surgical grafting
- Fourth-degree: Involves underlying fascia, muscle, or bone
Superficial (S/D) vs. deep (D) dermal burn, <24 hours post injury (Bailey & Love, p.691)
3. Assessment of Burn Size - TBSA
The Rule of Nines (Wallace Rule of Nines) for adults:
- Head and neck = 9%
- Each arm = 9%
- Anterior trunk = 18%
- Posterior trunk = 18%
- Each leg = 18%
- Perineum = 1%
The Lund and Browder chart is more accurate, especially in children, because it accounts for age-related changes in body proportions (head is larger relative to body in infants). The patient's palm (wrist crease to fingertips) = approximately 1% TBSA - useful for irregular burns.
Superficial (first-degree) burns are excluded from TBSA calculations for resuscitation purposes.
4. Admission Criteria (Burns Unit)
Burns meeting any of these criteria require admission to a burns unit (Bailey & Love's, p.688):
- Suspected airway or inhalational injury
- Any burn likely to require fluid resuscitation
- Any burn likely to require surgery
- Burns of significance to hands, face, feet, or perineum
- Suspicion of non-accidental injury
- Extremes of age
- High-tension electrical burns or concentrated hydrofluoric acid burns
- Social/psychiatric factors precluding home management
5. Major Determinants of Outcome
- Percentage TBSA involved
- Depth of burn
- Presence of inhalational injury
- Age and comorbidities
6. Initial Management - ATLS Approach
Management follows ABCDEF:
- A - Airway control (early intubation if airway burn suspected)
- B - Breathing/ventilation
- C - Circulation
- D - Disability (neurological status)
- E - Exposure with environmental control
- F - Fluid resuscitation
Airway Burns
Signs suggesting airway involvement:
- History of entrapment in smoke/hot gases
- Burns on palate or nasal mucosa; singed nasal hairs
- Deep burns around mouth/neck
- Hoarseness, stridor - these are late signs; intubation may already be impossible
The airway swells rapidly (4-24 hours post-burn). Early elective intubation is the treatment of choice. Cricotyroidotomy equipment must be available if delayed. Upper airway burns are managed by bypassing the obstruction with an ETT; lower airway/inhalational injury may progress to ARDS, usually after 48 hours - this determines the "anaesthetic window" for early surgery.
Inhalational Injury
Inhaled agents include CO (toxic/hypoxic), HCN (from burning synthetics), and direct thermal injury. Carboxyhaemoglobin >10% requires 100% O2 for 24 hours. Cyanide poisoning is treated with IV hydroxycobalamin (vitamin B12) - forms water-soluble cyanocobalamin. Nebulised heparin + N-acetylcysteine reduces fibrin cast formation in the lower airway. Bailey & Love's, p.689
Escharotomy
Full-thickness chest wall burns can cause a mechanical block to breathing (restricted chest expansion, CO2 retention, high ventilatory pressures). Treatment: escharotomy - scoring cuts through burned skin to allow chest expansion.
Escharotomy placement (Bailey & Love's, p.690):
| Site | Placement |
|---|
| Upper limb | Midaxial; anterior to elbow medially (avoid ulnar nerve) |
| Hand | Midline in digits; release muscle compartments if tight - best done in theatre |
| Lower limb | Midaxial; posterior to ankle medially (avoid long saphenous vein); anterior to head of fibula (avoid common peroneal nerve) |
| Chest | Lateral to nipples vertically; horizontal below clavicle and at xiphisternum level |
| General | Extend beyond the deep burn; diathermy bleeding vessels; apply haemostatic dressing and elevate limb |
7. Fluid Resuscitation
Fluid shifts occur due to the inflammatory capillary leak driven by the burn. Resuscitation is mandatory for:
- Children with burns >10% TBSA
- Adults with burns >15% TBSA
Parkland / Baxter Formula (crystalloid-based):
3-4 mL × kg body weight × %TBSA of Lactated Ringer's
- Half given in first 8 hours from time of burn
- Half given over subsequent 16 hours
The most recent ABA consensus formula recommends 2 mL/kg per %TBSA due to the tendency toward over-resuscitation with traditional formulas. (Schwartz's Principles of Surgery, p.282)
Muir and Barclay Formula (colloid-based, used in UK):
%TBSA × weight (kg) × 0.5 = one portion
- 6 portions given over 36 hours (4-hourly × 3 for first 12h; 6-hourly × 2 for next 12h; one portion over final 12h)
Monitoring of Resuscitation:
- Urine output is the primary endpoint: 0.5-1.0 mL/kg/h in adults
- Bolus 10 mL/kg if urine output drops with signs of hypoperfusion (tachycardia, cool peripheries, elevated lactate)
- Urine output >2 mL/kg/h should prompt reduction in infusion rate (avoid over-resuscitation)
- Complications of over-resuscitation: abdominal compartment syndrome, extremity compartment syndrome, intraocular compartment syndrome, pleural effusions
Patients with inhalational injury require significantly more fluid (average 5.76 mL/kg per %TBSA vs 3.98 without inhalation injury). (Schwartz's, p.282)
8. Burn Wound Treatment
Partial-Thickness Burns
Two key management goals:
- Prevent factors that cause the burn to "change group" (deepen) - infection is the primary culprit
- Control pain during dressing changes
Dressing options:
- Simple exposure (face only - painful, intensive nursing)
- Vaseline-impregnated gauze (± chlorhexidine), Mepitel (fenestrated silicone)
- Acticoat (silver nanocrystals) - antimicrobial, left for up to 7 days
- Hydrocolloids (Duoderm) - change every 3-5 days; high protease levels debride deeper areas; good evidence in burns
- Biosynthetic (Biobrane) / amniotic membranes - ideal for superficial burns, not for mixed-depth as they detach if applied to deep wounds
If the wound is heavily contaminated, formal wound cleaning under general anaesthetic is advised. Silver sulphadiazine cream is used for 2-3 days for contaminated wounds.
Full-Thickness Burns - Surgical Excision
The principle of early excision has transformed burn mortality. Two approaches:
1. Early Total Burn Excision:
- Excision of the entire burn as soon as possible after stabilisation
- Exploits three critical time windows:
- Anaesthetic window: Before inhalational injury progresses to ARDS (usually after 48h) - surgery must happen before this
- Haemodynamic window: Before progressive inflammatory vasodilation and coagulopathy reduce effectiveness of vasoconstrictors; removes the eschar that drives fluid shifts
- Bacterial window: Necrotic eschar is a bacterial culture medium; early removal reduces infection risk
2. Staged/Serial Debridement:
- Multiple operating sessions in the first week
- Shorter individual operating times, lower blood transfusion requirement
- Chosen when resources/facilities do not allow early total excision
Advantages of early excision (Bailey & Love's Summary Box 46.15, p.691):
- Reduces bacterial load
- Majority of surgery performed before substantial lung injury
- Allows effective use of vasoconstrictive tumescence fluids
- Enables earlier wound closure and rehabilitation
9. Wound Coverage
After excision, the wound requires coverage:
| Method | Indication |
|---|
| Split-thickness skin graft (STSG) | Most common; harvested from donor sites; meshed grafts allow coverage of larger areas |
| Full-thickness skin graft | Small areas, especially face/hands |
| Biological dressings (allograft, xenograft) | Temporary coverage while awaiting definitive grafting |
| Synthetic dressings (Integra, Biobrane) | Dermal substitutes for large burns |
| Cultured epithelial autografts (CEA) | Severe burns with limited donor sites; 3-week culture time required |
| Flap reconstruction | Areas over joints, specialised areas requiring bulk |
10. Nutrition
Hypermetabolism is one of the most profound responses to burn injury. Resting metabolic rate may rise by up to 200%, driving protein catabolism and loss of lean body mass. (Schwartz's, p.285)
- Early enteral feeding (within hours of admission) is safe for burns >20% TBSA; reduces hypermetabolism, preserves lean body mass, reduces ICU stay and wound infection rates
- Caloric need: Harris-Benedict × 2 or Curreri formula (25 kcal/kg/d + 40 kcal × %TBSA/d)
- Supplements: glutamine (immune modulation), antioxidant vitamins (C, E), trace minerals (selenium, zinc, copper)
- Oxandrolone (anabolic steroid): proven in paediatric burns to improve lean body mass, bone density, liver protein synthesis, and reduce length of stay
- Beta-blockers (especially propranolol in children): reduce heart rate, resting energy expenditure, and protein catabolism
11. Complications
| Complication | Notes |
|---|
| Infection / Sepsis | Most common cause of death in burns; surface wound colonisation vs. invasive infection |
| Inhalational ARDS | Develops 48h post-burn; drives ventilator management |
| Abdominal compartment syndrome | From over-resuscitation |
| Extremity compartment syndrome | From oedema or circumferential burns; requires escharotomy/fasciotomy |
| Acute renal failure | From myoglobinuria (electrical burns), hypovolaemia |
| Hypertrophic scarring | Deep dermal burns that heal spontaneously; treated with pressure garments, silicone, or surgical revision |
| Contractures | Especially over joints; require splinting and eventually surgical release |
| Curling's ulcer | Stress ulcer; prophylaxis with H2 blockers/PPIs |
| Heterotopic ossification | Rare; around joints in major burns |
12. Special Considerations
Chemical Burns
- Alkali burns penetrate deeply and cause ischaemic necrosis (more dangerous than acid)
- Immediate copious irrigation until pH is neutral; remove all particles from fornices
- Hydrofluoric acid: systemic fluoride toxicity; treat with topical/intralesional/IV calcium gluconate
Electrical Burns
- Entry and exit wounds with internal damage disproportionate to surface area
- Risk of deep muscle necrosis, rhabdomyolysis, renal failure
- Cardiac monitoring mandatory (arrhythmias, arrest)
- High-tension burns require burns unit admission
Burns in Children
- Thinner skin - deeper burns from the same exposure
- Larger surface area to body mass ratio - greater fluid losses; larger fluid volumes needed per kg
- Immature kidneys: urine output goal 1 mL/kg/h (vs. 0.5 in adults)
- Scald injuries most common in <2 years; flame burns more common in teenagers
- Carbon monoxide falsely elevates pulse oximetry - arterial blood gas mandatory
13. Prognosis
Mortality in burns correlates with:
- Increasing age
- Increasing %TBSA
- Presence of inhalational injury
The Baux score (age + %TBSA) is a simple prognostic tool; a score >140 historically carried near-certain mortality, though with modern burn centre care, even this has improved.
Sources:
- Bailey and Love's Short Practice of Surgery, 28th Edition - Ch. 46 Burns
- Schwartz's Principles of Surgery, 11th Edition - Ch. 8 Burns
- Sabiston Textbook of Surgery - Paediatric Burns