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Poster Summary

Title: Successfully Conducted Autologous Bone Marrow Transplant (BMT) in Relapsed/Refractory Classical Hodgkin Lymphoma - A New Journey Started at the Regional Cancer Centre, Gwalior, Madhya Pradesh
Authors: Dr. Anil Sharma, Dr. Gunjan Shrivastava, Dr. Nirmal Jain, Dr. Pankaj Gandotra, Dr. B.R. Shrivastava Institution: Department of Medical Oncology & BMT, Cancer Hospital & Research Institute, Gwalior, Madhya Pradesh

Introduction

The Cancer Hospital & Research Institute, Gwalior is a Government of India-funded Regional Cancer Centre, established in 1977. It handles nearly 10,000 new cancer registrations annually, with approximately 50-60 patients requiring BMT every year. A dedicated BMT unit was set up in October 2023. This poster reports the first successful autologous hematopoietic stem cell transplantation (HSCT) performed there in a patient with relapsed/refractory classical Hodgkin lymphoma.

Methodology

  • A dedicated two-room BMT unit with trained physicians and nursing staff was established.
  • Patient: 42-year-old male with relapsed/refractory classical Hodgkin lymphoma.
  • Received 3 cycles of GDP chemotherapy prior to transplant.
  • Stem cell mobilization performed using G-CSF.
  • Stem cell collection and cryopreservation achieved successfully:
    • Collection volume: 342 mL
    • CD34+ count: 9.21 million/kg
  • BEAM conditioning regimen administered:
    • BCNU 300 mg/m²
    • Cytarabine 400 mg/m²
    • Etoposide 200 mg/m²
    • Melphalan 140 mg/m²
  • Standard supportive care and transplant protocols followed.

Results

  • Successful stem cell infusion on Day 0
  • CD34+ infused: 8.79 million/kg
  • Febrile neutropenia developed between Day +5 and Day +15 - managed successfully per protocol.
  • Neutrophil engraftment achieved on Day +13
  • Platelet engraftment achieved on Day +17
  • Brentuximab vedotin maintenance initiated from Day +60 post-transplant
  • Patient remains disease-free at 30 months follow-up

Discussion

Autologous HSCT remains an effective therapeutic strategy for relapsed/refractory Hodgkin lymphoma responsive to salvage chemotherapy. The successful completion of this first transplant demonstrates the feasibility of establishing advanced BMT services in regional cancer centres, making accessible and cost-effective transplant care available to nearly 7.5 million people in and around the region.

Venue: Cancer Hospital and Research Institute, Gwalior

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Here's what's packed into the poster:
Visual Design
  • Deep space gradient background with glowing purple/blue accents
  • Gradient title text in cyan, indigo, and pink
Interactive Features
  • 6 animated stat cards (hover to lift + ripple click effect) showing key numbers: patient age, CD34+ counts, engraftment days, and 30-month disease-free status
  • Animated progress bars for neutrophil engraftment, platelet engraftment, and brentuximab start - they fill up on load
  • Hover tooltips on all stat cards explaining what each number means
  • Timeline with colour-coded dots for each post-transplant milestone from Day 0 to 30 months
  • BEAM regimen table with drug doses in a clean styled layout
  • Outcome grid with emoji icons for all 8 key results
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BMT Hodgkin Lymphoma

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Here's what's in the 6-slide deck (widescreen 13.3" format):
SlideContent
1 - TitleFull title, authors, institution, and 5 key institution stats in coloured cards
2 - IntroductionBackground text, 3 highlight boxes (Regional Centre / 10,000 cases / First HSCT), and the 7.5M people impact note
3 - Methodology7-step numbered protocol list + full BEAM conditioning table with drug doses + stem cell collection stats
4 - TimelineVisual horizontal timeline from Day 0 to 30 months with colour-coded milestone cards + 4 outcome metric boxes
5 - Results8 large bold stat cards (all numbers at a glance) + results bullet summary
6 - DiscussionKey discussion text, 4 takeaway boxes, and venue footer bar
The design uses a deep navy/space background with purple, cyan, green, pink, and amber accents - consistent with the interactive HTML poster.

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BMT Hodgkin Lymphoma Infographic
The image covers all the data in one visual page:
  • Top row - 5 coloured stat cards (institution founding, annual cases, BMT patients, unit launch date, population served)
  • Introduction section with the background context
  • Methodology with the 7-step numbered protocol
  • BEAM Regimen table with all 4 drug doses
  • Horizontal timeline from Day 0 to 30 months with milestone markers
  • Outcome metrics with the 4 key results
  • Discussion summarising the significance
  • Footer with the venue details
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