Given the library doesn't have a dedicated emergency medicine textbook, I'll now compile a comprehensive, authoritative answer from my medical knowledge, organized by department. This is a well-established clinical topic.
100 Most Common ER Emergency Cases: First-Line Treatment & First Aid
Organized by medical specialty. All treatments are first-line/immediate management.
π« CARDIOVASCULAR (1β12)
1. ST-Elevation Myocardial Infarction (STEMI)
- First Aid: Aspirin 325 mg chewed immediately, supplemental Oβ if SpOβ <90%
- First-Line Tx: Activate cath lab for primary PCI within 90 min; if unavailable, fibrinolysis (tPA/streptokinase); anticoagulation (heparin), P2Y12 inhibitor (ticagrelor/clopidogrel), nitrates for pain, morphine PRN
2. Non-ST-Elevation ACS (NSTEMI/UA)
- First Aid: Aspirin 325 mg, sublingual nitroglycerin, IV access, Oβ
- First-Line Tx: Dual antiplatelet (aspirin + ticagrelor), anticoagulation (LMWH/heparin), risk-stratify with TIMI/GRACE score, early invasive strategy for high-risk
3. Acute Decompensated Heart Failure (Pulmonary Edema)
- First Aid: Sit upright, high-flow Oβ, legs dependent
- First-Line Tx: IV furosemide 40β80 mg, IV nitroglycerin (if SBP >90), NIV (CPAP/BiPAP), morphine carefully; intubate if failing
4. Hypertensive Emergency (BP >180/120 + end-organ damage)
- First Aid: Calm patient, IV access, monitor
- First-Line Tx: IV labetalol or nicardipine; reduce MAP by 25% in first hour only; nitroprusside for hypertensive encephalopathy; avoid rapid overcorrection
5. Cardiac Tamponade
- First Aid: IV fluids to maintain preload, supplemental Oβ
- First-Line Tx: Emergent pericardiocentesis (subxiphoid approach); echo-guided preferred; surgical drainage if reaccumulates; avoid positive pressure ventilation
6. Aortic Dissection (Type A)
- First Aid: IV access Γ2, supplemental Oβ, BP monitoring both arms, analgesia
- First-Line Tx: Type A β emergent surgery; Type B β IV esmolol (HR <60) then nitroprusside; target SBP 100β120 mmHg; CT angiography to confirm
7. Ventricular Fibrillation / Pulseless VT (Cardiac Arrest)
- First Aid: CPR immediately (30:2), call for defibrillator
- First-Line Tx: Defibrillation 200 J (biphasic); epinephrine 1 mg IV q3β5 min; amiodarone 300 mg IV; continue ACLS protocol; identify and treat reversible H's and T's
8. Complete Heart Block (3rd Degree AV Block)
- First Aid: Atropine 0.5 mg IV (up to 3 mg), transcutaneous pacing
- First-Line Tx: Transvenous pacing; dopamine/epinephrine infusion as bridge; treat underlying cause (MI, drug toxicity)
9. Supraventricular Tachycardia (SVT)
- First Aid: Valsalva maneuver, carotid sinus massage
- First-Line Tx: Adenosine 6 mg rapid IV push (then 12 mg); if unstable β synchronized cardioversion 50β100 J; calcium channel blocker (diltiazem) or beta-blocker if recurrent
10. Atrial Fibrillation with Rapid Ventricular Response
- First Aid: Oβ, IV access, 12-lead ECG
- First-Line Tx: Rate control: IV diltiazem or metoprolol; if unstable β cardioversion 120β200 J; anticoagulate if AF >48 h; treat precipitating cause
11. Massive Pulmonary Embolism
- First Aid: Oβ, IV access, position upright, avoid hypotension-inducing agents
- First-Line Tx: If unstable (shock/arrest): systemic thrombolysis (alteplase 100 mg IV over 2 h); if stable: anticoagulate with heparin; catheter-directed therapy or surgical embolectomy as escalation
12. Acute Limb Ischemia
- First Aid: Anticoagulate immediately (heparin), protect limb, analgesia
- First-Line Tx: Emergent surgical embolectomy or catheter-directed thrombolysis; 6-hour window critical; Doppler assessment
π§ NEUROLOGY (13β22)
13. Ischemic Stroke
- First Aid: FAST recognition, IV access, non-contrast CT head immediately
- First-Line Tx: tPA (alteplase 0.9 mg/kg, max 90 mg) within 4.5 hours if no contraindications; mechanical thrombectomy within 24 h for large vessel occlusion; aspirin 325 mg if tPA not given; strict BP management
14. Hemorrhagic Stroke (Intracerebral Hemorrhage)
- First Aid: Airway protection, IV access, avoid anticoagulants
- First-Line Tx: Reverse anticoagulation (vitamin K, PCC, FFP); target SBP <140 mmHg (labetalol, nicardipine); neurosurgery consult; ICP management if needed
15. Subarachnoid Hemorrhage
- First Aid: "Worst headache of life" β IV access, analgesics, strict bed rest
- First-Line Tx: CT head β LP if CT negative; nimodipine 60 mg q4h (vasospasm prevention); BP control; emergent neurosurgery/interventional neuroradiology for aneurysm clipping/coiling
16. Status Epilepticus
- First Aid: Protect airway, lateral decubitus, time the seizure, oxygen
- First-Line Tx: Lorazepam 0.1 mg/kg IV (or midazolam 10 mg IM if no IV); if persists β fosphenytoin or valproate IV; refractory β phenobarbital or propofol infusion; check glucose
17. Meningitis (Bacterial)
- First Aid: Isolate, IV access, do NOT delay treatment for LP
- First-Line Tx: Ceftriaxone 2 g IV + vancomycin 15β20 mg/kg + dexamethasone 0.15 mg/kg IV (give before or with first antibiotic dose); LP only after CT to rule out mass; empiric acyclovir if encephalitis suspected
18. Hypertensive Encephalopathy
- First Aid: IV access, Oβ, quiet environment
- First-Line Tx: IV labetalol or nicardipine; target 20β25% MAP reduction over 1 hour; avoid nitroprusside first-line; seizure prophylaxis if needed
19. Acute Spinal Cord Compression
- First Aid: Spinal precautions, immobilization
- First-Line Tx: High-dose dexamethasone IV; emergent MRI; neurosurgical decompression; treat underlying cause (epidural abscess β antibiotics + surgery)
20. Guillain-BarrΓ© Syndrome (Acute)
- First Aid: Monitor respiratory function (FVC, NIF), IV access
- First-Line Tx: IVIG 0.4 g/kg/day Γ 5 days OR plasmapheresis; intubate if FVC <20 mL/kg or NIF < β25 cmHβO; DVT prophylaxis; pain management
21. Wernicke's Encephalopathy
- First Aid: Do NOT give glucose before thiamine
- First-Line Tx: Thiamine 500 mg IV TID Γ 3 days; then 250 mg/day; correct electrolytes; glucose after thiamine
22. Cerebral Herniation / Raised ICP
- First Aid: Head of bed 30Β°, avoid hypotension/hypoxia, hyperventilate briefly
- First-Line Tx: Mannitol 1 g/kg IV bolus OR hypertonic saline (3% NaCl); intubation with target PaCOβ 35β40; dexamethasone if vasogenic edema; emergent neurosurgery
π« RESPIRATORY (23β32)
23. Acute Severe Asthma (Status Asthmaticus)
- First Aid: Sit upright, Oβ to maintain SpOβ >94%, nebulized salbutamol
- First-Line Tx: Salbutamol 2.5 mg + ipratropium 0.5 mg nebulized q20 min Γ 3; IV methylprednisolone 125 mg; magnesium sulphate 2 g IV over 20 min; heliox; intubate if exhausted/silent chest
24. Acute Exacerbation of COPD
- First Aid: Controlled Oβ (24β28%, target SpOβ 88β92%), position upright
- First-Line Tx: Salbutamol + ipratropium nebulized; systemic steroids (prednisolone 40 mg PO or IV methylprednisolone); antibiotics if purulent sputum (amoxicillin-clavulanate or azithromycin); NIV (BiPAP) if pH <7.35; avoid high-flow Oβ
25. Tension Pneumothorax
- First Aid: CLINICAL DIAGNOSIS β do not wait for CXR; decompress immediately
- First-Line Tx: Needle decompression β 2nd ICS, MCL, 14β16G cannula; then chest tube 4th/5th ICS anterior axillary line; Oβ; IV fluids if hypotensive
26. Spontaneous Pneumothorax
- First Aid: Oβ (high-flow accelerates reabsorption), monitor
- First-Line Tx: Small (<2 cm) + stable: observation; large or symptomatic: aspiration or chest tube; pleural drainage
27. Acute Respiratory Distress Syndrome (ARDS)
- First Aid: Oβ, IV access, position prone if severe
- First-Line Tx: Lung-protective ventilation: TV 6 mL/kg IBW, plateau pressure <30 cmHβO, PEEP titrated; treat underlying cause; prone positioning if PaOβ/FiOβ <150; neuromuscular blockade if severe
28. Massive Hemothorax
- First Aid: IV access Γ2, fluid resuscitation, type and crossmatch
- First-Line Tx: Large-bore chest tube (28β32 Fr); cell salvage autotransfusion; if >1.5 L on drainage or >200 mL/h β emergent thoracotomy; blood products
29. Epiglottitis
- First Aid: Keep patient calm and sitting upright; do NOT examine throat in children; call anesthesia and ENT immediately
- First-Line Tx: Secure airway (intubation by most experienced provider, in OR); ceftriaxone 2 g IV; dexamethasone 0.6 mg/kg; no tongue depressor in children
30. Foreign Body Airway Obstruction
- First Aid: Conscious adult: back blows Γ 5 + abdominal thrusts (Heimlich) Γ 5; unconscious: CPR + look in mouth before ventilating
- First-Line Tx: Direct laryngoscopy + Magill forceps; cricothyrotomy if cannot intubate or oxygenate; bronchoscopic removal for lower airway
31. Pneumonia with Sepsis
- First Aid: Oβ, IV access, blood cultures before antibiotics
- First-Line Tx: Antibiotics within 1 hour: ceftriaxone + azithromycin (CAP); piperacillin-tazobactam + vancomycin (HAP/VAP); IV fluids 30 mL/kg; vasopressors if fluid-refractory; consider ICU
32. Acute Upper Airway Angioedema
- First Aid: High-flow Oβ, call anesthesia for airway immediately, IV access
- First-Line Tx: Epinephrine 0.3β0.5 mg IM (anterolateral thigh); IV diphenhydramine + ranitidine; methylprednisolone 125 mg IV; early intubation before edema progresses; C1 esterase inhibitor for hereditary angioedema
π₯ TRAUMA & SURGICAL (33β44)
33. Polytrauma / Major Trauma
- First Aid: Primary survey: ABCDE; C-spine immobilization; hemorrhage control
- First-Line Tx: Damage control resuscitation: 1:1:1 pRBC:FFP:platelets; permissive hypotension (SBP 80β90) until hemorrhage control; TXA within 3 hours (1 g IV); FAST exam; emergent OR if unstable
34. Hemorrhagic Shock
- First Aid: Direct pressure on bleeding, elevate extremities, two large-bore IVs
- First-Line Tx: Blood products (pRBC, FFP) over crystalloid; TXA 1 g IV; vasopressors if needed; definitive hemorrhage control (surgery/IR); massive transfusion protocol activation
35. Tension Pneumothorax (Trauma)
36. Flail Chest
- First Aid: Oβ, analgesia, monitor
- First-Line Tx: Adequate analgesia (epidural/intercostal nerve blocks); lung-protective ventilation; treat underlying pneumothorax/hemothorax; surgical stabilization for refractory respiratory failure
37. Traumatic Brain Injury (Severe)
- First Aid: Airway protection, C-spine immobilization, avoid hypotension and hypoxia
- First-Line Tx: Intubation (RSI); target SBP >90, SpOβ >95%, PaCOβ 35β40; mannitol/hypertonic saline for ICP; neurosurgery for epidural/subdural hematoma; ICP monitoring
38. Spinal Cord Injury (Acute Cervical)
- First Aid: Rigid collar, log-roll precautions, IV access
- First-Line Tx: Maintain MAP 85β90 (vasopressors); avoid hypoxia; emergent MRI; methylprednisolone (controversial, some centers); spinal decompression if indicated; ICU admission
39. Abdominal Compartment Syndrome
- First Aid: Decompress NG tube, urinary catheter, positioning
- First-Line Tx: Bladder pressure monitoring; if >20 mmHg + organ dysfunction β emergent decompressive laparotomy; remove tight dressings/eschar; neuromuscular blockade trial
40. Ruptured Abdominal Aortic Aneurysm
- First Aid: Two large-bore IVs, permissive hypotension, call vascular surgery STAT
- First-Line Tx: Emergent EVAR or open repair; massive transfusion protocol; minimize pre-op intervention time; do NOT over-resuscitate
41. Acute Surgical Abdomen (Perforation)
- First Aid: IV access, NPO, analgesia (does NOT mask examination), NG tube
- First-Line Tx: IV antibiotics (piperacillin-tazobactam); IV fluids; emergent surgery (laparotomy/laparoscopy); upright CXR for free air; CT abdomen if stable
42. Testicular Torsion
- First Aid: Analgesia, urgent urology consult, do NOT delay for ultrasound
- First-Line Tx: Manual detorsion ("open book" technique) as bridge; emergent surgical exploration and orchiopexy within 6 hours; bilateral orchiopexy
43. Crush Syndrome / Rhabdomyolysis
- First Aid: IV access, aggressive IV fluids before extrication if possible
- First-Line Tx: IV NS/LR at 1β1.5 L/h targeting urine output 200β300 mL/h; urinary alkalinization (sodium bicarbonate) for myoglobinuria; monitor KβΊ, CaΒ²βΊ, renal function; dialysis if AKI
44. Compartment Syndrome (Extremity)
- First Aid: Remove all constrictive dressings/casts; elevate limb to heart level
- First-Line Tx: Pressure >30 mmHg or Ξ pressure <30 mmHg β emergent fasciotomy; analgesia; monitor post-op for reperfusion injury
π©Ί GASTROINTESTINAL (45β51)
45. Upper GI Bleed (Variceal)
- First Aid: IV access Γ2, NPO, type and screen, Oβ
- First-Line Tx: Octreotide 50 mcg IV bolus then 50 mcg/h; ceftriaxone 1 g IV (SBP prophylaxis); IV PPI; emergent endoscopy within 12 h; band ligation; Sengstaken-Blakemore tube if uncontrolled; TIPS
46. Upper GI Bleed (Non-Variceal)
- First Aid: IV access Γ2, NPO, resuscitate
- First-Line Tx: IV PPI (pantoprazole 80 mg bolus then 8 mg/h); endoscopy within 24 h (12 h if high risk); epinephrine injection + thermal/clip at endoscopy; H. pylori testing
47. Acute Liver Failure
- First Aid: IV access, glucose monitoring, avoid hepatotoxic drugs
- First-Line Tx: N-acetylcysteine (all causes, especially paracetamol); IV dextrose for hypoglycemia; lactulose for encephalopathy; manage coagulopathy (FFP for bleeding only, not prophylactically); urgent liver transplant assessment
48. Acute Pancreatitis (Severe)
- First Aid: NPO, IV access, fluid resuscitation, analgesia
- First-Line Tx: Aggressive IV crystalloid (250β500 mL/h LR preferred); pain control (IV morphine/hydromorphone); antibiotics only if infected necrosis confirmed; ERCP if gallstone pancreatitis with cholangitis; ICU if severe
49. Mesenteric Ischemia (Acute)
- First Aid: IV access, analgesia, NPO; suspect in any elderly patient with pain out of proportion to exam
- First-Line Tx: IV heparin; CT angiography; emergent surgery/catheter-directed thrombolysis; bowel resection if necrosis; broad-spectrum antibiotics
50. Bowel Obstruction (Complete)
- First Aid: NPO, NG decompression, IV access, electrolytes
- First-Line Tx: IV fluids, electrolyte correction; NG tube decompression; serial abdominal exams; CT abdomen; emergent surgery if strangulation/perforation; water-soluble enema for colonic obstruction
51. Acute Cholangitis (Ascending)
- First Aid: IV access, IV fluids, blood cultures Γ 2, analgesia
- First-Line Tx: IV antibiotics (piperacillin-tazobactam or meropenem for severe); IV fluids; urgent ERCP within 24β48 h; percutaneous drainage if ERCP fails
π§ͺ METABOLIC / ENDOCRINE (52β58)
52. Diabetic Ketoacidosis (DKA)
- First Aid: IV access, glucose check, IV fluids
- First-Line Tx: IV NS 1 L/h Γ 2 h, then 0.45% NS; insulin 0.1 u/kg/h IV infusion; potassium replacement when KβΊ >3.5; switch to dextrose-containing fluids when glucose <250; monitor KβΊ, bicarbonate hourly; identify precipitant
53. Hyperosmolar Hyperglycemic State (HHS)
- First Aid: IV access, IV fluids aggressively, glucose check
- First-Line Tx: IV 0.9% NaCl (1 L/h initially); low-dose insulin only after fluid resuscitation; correct NaβΊ slowly; heparin anticoagulation (high thrombosis risk); identify precipitant
54. Severe Hypoglycemia
- First Aid: If conscious: oral glucose (juice/dextrose tablets); unconscious: do NOT give PO
- First-Line Tx: D50W 25β50 mL IV bolus; or glucagon 1 mg IM/SC if no IV access; recheck glucose in 15 min; identify cause; oral carbohydrates once alert
55. Thyroid Storm (Thyrotoxic Crisis)
- First Aid: IV access, cooling measures, IV fluids, Oβ
- First-Line Tx: PTU 200 mg q4h (blocks synthesis + peripheral conversion) then Lugol's iodine 5 drops q6h (1 hour after PTU); propranolol 1 mg IV q5 min or 40β80 mg PO q6h; dexamethasone 2 mg IV q6h; treat precipitant; cooling
56. Adrenal Crisis (Addisonian Crisis)
- First Aid: IV access, IV fluids aggressively, glucose check
- First-Line Tx: Hydrocortisone 100 mg IV bolus then 50β100 mg q6h; IV 0.9% NaCl with dextrose; treat precipitating illness; fludrocortisone once oral intake possible
57. Severe Hyponatremia (NaβΊ <120 mEq/L with symptoms)
- First Aid: IV access, assess for cerebral edema
- First-Line Tx: If symptomatic (seizure/coma): 100 mL 3% NaCl IV over 10 min (Γ3 if needed); target NaβΊ rise 4β6 mEq/L in first hour, then β€8β10 mEq/L/24h (avoid osmotic demyelination); water restriction; treat cause
58. Hyperkalemia (KβΊ >6.5 or with ECG changes)
- First Aid: IV access, ECG immediately, calcium gluconate if ECG changes
- First-Line Tx: Calcium gluconate 10 mL 10% IV (membrane stabilization); insulin 10 U IV + dextrose 50%; salbutamol 10β20 mg nebulized; sodium bicarbonate; furosemide; sodium polystyrene or patiromer; dialysis for refractory
π¦ INFECTIOUS DISEASE / SEPSIS (59β64)
59. Septic Shock
- First Aid: IV access Γ2, blood cultures Γ 2, Oβ, lactate
- First-Line Tx: Antibiotics within 1 hour (broad spectrum: piperacillin-tazobactam + vancomycin); 30 mL/kg IV crystalloid; norepinephrine if MAP <65 after fluids; stress-dose steroids (hydrocortisone 200 mg/day) if refractory; source control
60. Necrotizing Fasciitis
- First Aid: IV access, analgesia, mark skin borders
- First-Line Tx: Emergent surgical debridement (within 6β12 h β key to survival); IV antibiotics: piperacillin-tazobactam + clindamycin + vancomycin; IV fluids; ICU; hyperbaric Oβ adjunct; serial debridement
61. Ludwig's Angina
- First Aid: Airway is priority β call anesthesia and ENT immediately
- First-Line Tx: Secure airway (awake fiberoptic if possible); IV ampicillin-sulbactam or clindamycin + ceftriaxone; surgical drainage; avoid blind intubation
62. Toxic Shock Syndrome
- First Aid: IV access, fluids, remove foreign body/tampon/dressing
- First-Line Tx: IV fluids aggressively; anti-staphylococcal antibiotics (cloxacillin/vancomycin + clindamycin); IVIG 2 g/kg (toxin neutralization); vasopressors; source control
63. Malaria (Severe/Cerebral)
- First Aid: IV access, glucose check, Oβ
- First-Line Tx: IV artesunate 2.4 mg/kg (preferred); if unavailable: IV quinine; dextrose for hypoglycemia; ICU care; exchange transfusion (rare); treat complications (seizures, AKI)
64. Rabies Post-Exposure (Prophylaxis)
- First Aid: Wash wound thoroughly with soap and water for 15 min; iodine/70% ethanol
- First-Line Tx: HRIG 20 IU/kg (infiltrate wound + remainder IM); rabies vaccine (HDCV) days 0, 3, 7, 14; do NOT suture wound initially; report to public health
π TOXICOLOGY / POISONING (65β73)
65. Paracetamol (Acetaminophen) Overdose
- First Aid: IV access, time of ingestion, paracetamol level at 4 hours
- First-Line Tx: N-acetylcysteine (NAC): 150 mg/kg IV over 1h β 50 mg/kg over 4h β 100 mg/kg over 16h; activated charcoal if <2 hours; use Rumack-Matthew nomogram; liver function monitoring
66. Opioid Overdose
- First Aid: Airway positioning, rescue breathing if apneic
- First-Line Tx: Naloxone 0.4β2 mg IV/IM/IN; repeat q2β3 min (up to 10 mg); infusion 2/3 of reversal dose/hour for long-acting opioids; monitor for re-narcotization
67. Benzodiazepine Overdose
- First Aid: Airway management, positioning, Oβ
- First-Line Tx: Supportive care; flumazenil 0.2 mg IV (cautious use β may precipitate seizures in dependent patients); airway protection; do NOT use flumazenil in mixed ingestions
68. Tricyclic Antidepressant (TCA) Overdose
- First Aid: IV access, 12-lead ECG (QRS widening is key warning)
- First-Line Tx: Sodium bicarbonate 1β2 mEq/kg IV bolus if QRS >100 ms or arrhythmia/hypotension; target pH 7.45β7.55; intubation if seizures; avoid physostigmine; lipid emulsion therapy adjunct
69. Organophosphate Poisoning
- First Aid: Remove contaminated clothing, decontaminate with water; avoid self-exposure
- First-Line Tx: Atropine 2β4 mg IV q5β10 min until secretions dry (may need massive doses); pralidoxime (2-PAM) 1β2 g IV over 15β30 min then infusion; intubation; benzodiazepines for seizures
70. Carbon Monoxide Poisoning
- First Aid: Remove from source immediately, 100% Oβ via NRB mask
- First-Line Tx: 100% Oβ (reduces CO half-life from 5h to 1h); hyperbaric Oβ if loss of consciousness, cardiac involvement, or COHb >25%; treat seizures; cardiac monitoring
71. Cyanide Poisoning
- First Aid: Remove from exposure, 100% Oβ
- First-Line Tx: Hydroxocobalamin 5 g IV over 15 min (preferred); or sodium nitrite + sodium thiosulfate (if no hydroxocobalamin); 100% Oβ; decontaminate skin
72. Digoxin Toxicity
- First Aid: IV access, ECG, check KβΊ (hypokalemia worsens toxicity)
- First-Line Tx: Digoxin-specific antibody fragments (Fab β Digibind): dose based on ingestion amount or serum level; correct KβΊ, MgΒ²βΊ; atropine for bradycardia; avoid calcium (may worsen)
73. Beta-Blocker / Calcium Channel Blocker Overdose
- First Aid: IV access, ECG, glucose check
- First-Line Tx: Calcium gluconate/chloride IV; glucagon 3β5 mg IV bolus (beta-blocker); high-dose insulin + dextrose (1 u/kg/h); IV lipid emulsion 20%; norepinephrine; pacing for refractory bradycardia; ECMO for refractory shock
π©Έ HEMATOLOGY / ONCOLOGY (74β78)
74. Massive Hemorrhage / Coagulopathy
- First Aid: Direct pressure, tourniquet for extremities, IV access
- First-Line Tx: Massive transfusion protocol (1:1:1); TXA 1 g IV within 3 h; FFP, cryoprecipitate, platelets; correct hypothermia and acidosis; surgical source control
75. Hyperleukocytosis / Leukostasis
- First Aid: Avoid red cell transfusion (raises viscosity), hydration
- First-Line Tx: Emergent leukapheresis; hydroxyurea 50β100 mg/kg/day; allopurinol + hydration for TLS; avoid pRBC transfusion; urgent hematology consult
76. Tumor Lysis Syndrome (TLS)
- First Aid: IV fluids aggressively, monitor electrolytes
- First-Line Tx: IV fluids 200 mL/h; allopurinol or rasburicase (rasburicase preferred for severe); treat hyperkalemia, hyperphosphatemia, hypocalcemia; dialysis if refractory; avoid nephrotoxins
77. Febrile Neutropenia
- First Aid: Blood cultures Γ 2 (peripheral + central), IV access, Oβ
- First-Line Tx: Antibiotics within 1 hour: cefepime or piperacillin-tazobactam IV (add vancomycin if line infection/hemodynamic instability); G-CSF in selected cases; avoid NSAIDs; temperature >38.3Β°C + ANC <500
78. Sickle Cell Vaso-Occlusive Crisis / Acute Chest Syndrome
- First Aid: Oβ, IV access, analgesia, IV fluids
- First-Line Tx: IV morphine (PCA); IV fluids; incentive spirometry; Oβ if SpOβ <95%; exchange transfusion for acute chest syndrome; hydroxyurea long-term; blood transfusion if severe anemia
π« RENAL / UROLOGICAL (79β83)
79. Acute Kidney Injury (Oliguric/Anuric)
- First Aid: Catheterize to rule out obstruction, IV access, stop nephrotoxic drugs
- First-Line Tx: IV fluid challenge (500 mL NS over 30 min) if pre-renal; furosemide challenge; dialysis indications: AEIOU (Acidosis, Electrolytes, Ingestion, Overload, Uremia); treat underlying cause
80. Urological Sepsis / Pyelonephritis
- First Aid: IV access, urine cultures, blood cultures
- First-Line Tx: IV ceftriaxone or ciprofloxacin; IV fluids; IV paracetamol + buscopan for pain; drain obstruction (JJ stent/nephrostomy) if obstructive uropathy; ICU if septic shock
81. Renal Colic with Obstruction and Infection
- First Aid: IV access, analgesia (IV ketorolac or morphine), antiemetics
- First-Line Tx: IV antibiotics if infected (surgical emergency); IV fluids; urgent urology consult; percutaneous nephrostomy or JJ stent; CT KUB for diagnosis; medical expulsive therapy if no infection
82. Ruptured Ectopic Pregnancy
- First Aid: IV access Γ2, IV fluids, type and crossmatch, call OB/GYN immediately
- First-Line Tx: Emergent surgical intervention (salpingectomy); blood transfusion; do NOT delay for imaging if hemodynamically unstable; if stable: transvaginal USS confirmation then MTX if criteria met
83. Urinary Retention (Acute)
- First Aid: Urinary catheterization immediately; monitor post-void residual
- First-Line Tx: Foley catheter (14β16 Fr); if impossible β suprapubic catheter; treat underlying BPH (alpha-blockers); check for medications causing retention; monitor for post-obstructive diuresis
πΆ OBSTETRIC / GYNECOLOGICAL (84β88)
84. Eclampsia
- First Aid: Position left lateral decubitus, Oβ, IV access, call OB
- First-Line Tx: Magnesium sulphate 4 g IV over 5β10 min then 1β2 g/h infusion (seizure prophylaxis/termination); IV labetalol or hydralazine for BP >160/110; deliver fetus regardless of gestational age (after stabilization); calcium gluconate for Mg toxicity
85. Placental Abruption / APH
- First Aid: IV access Γ2, type and screen, IV fluids, fetal monitoring
- First-Line Tx: IV fluids; blood transfusion; urgent delivery (vaginal if fetus deceased; C-section if fetal distress); DIC management (FFP, platelets, cryoprecipitate); massive transfusion protocol
86. Postpartum Hemorrhage (PPH)
- First Aid: Bimanual uterine massage, estimate blood loss, IV access Γ2
- First-Line Tx: Oxytocin 10 IU IM/IV; ergometrine 0.5 mg IM (if no hypertension); carboprost 0.25 mg IM q15 min; misoprostol 800 mcg PR; uterine balloon tamponade; TXA 1 g IV; surgical (B-Lynch suture, hysterectomy)
87. Ovarian Torsion
- First Aid: IV access, analgesia, urgent gynaecology consult
- First-Line Tx: Emergent laparoscopic detorsion (within 6 hours); cystectomy if cyst; oophorectomy if necrotic; Doppler USS but clinical diagnosis drives decision
88. Hyperemesis Gravidarum with Severe Dehydration
- First Aid: IV access, IV fluids, antiemetics, nothing PO initially
- First-Line Tx: IV Hartmann's/NS; IV thiamine 100 mg before dextrose; IV ondansetron or promethazine; correct electrolytes; TPN if oral nutrition impossible; screen for alternative diagnoses
ποΈ OPHTHALMOLOGY / ENT (89β93)
89. Chemical Eye Injury (Alkali/Acid)
- First Aid: Immediate copious irrigation with water/saline for β₯30 minutes; remove contact lenses; pH check β continue until pH 7.0β7.4
- First-Line Tx: Topical anesthetic for compliance with irrigation; emergent ophthalmology; topical steroids + antibiotics; alkali burns are worse (deeper penetration)
90. Acute Angle-Closure Glaucoma
- First Aid: IV access, analgesia, antiemetics; urgent ophthalmology
- First-Line Tx: IV acetazolamide 500 mg + PO 250 mg q6h; IV mannitol 1β2 g/kg; topical timolol, pilocarpine 2%, and prednisolone; urgent laser peripheral iridotomy
91. Central Retinal Artery Occlusion (CRAO)
- First Aid: Ocular massage (15 s on, 15 s off Γ 15 min); reduce IOP urgently
- First-Line Tx: Ocular massage; IV acetazolamide; anterior chamber paracentesis; sublingual isosorbide dinitrate; rebreathing into bag; thrombolytics if within 4.5 h (selected centres); treat systemic risk factors urgently
92. Epistaxis (Posterior / Severe)
- First Aid: Lean forward, pinch anterior nares Γ 10β20 min, ice
- First-Line Tx: Anterior: silver nitrate cautery or anterior nasal packing (Merocel/BIPP); posterior: Foley balloon or Rapid Rhino posterior pack; ENT consult; check BP and coagulopathy; reversal of anticoagulants if needed
93. Sudden Hearing Loss (SSNHL)
- First Aid: Urgent ENT referral (within 24β48 h is time-critical)
- First-Line Tx: Oral prednisolone 1 mg/kg/day Γ 14 days (or intratympanic dexamethasone); MRI IAM to exclude acoustic neuroma; hyperbaric Oβ (adjunct in some centres); treat within 2 weeks for best outcome
π§ PEDIATRIC EMERGENCIES (94β97)
94. Febrile Seizure / Pediatric Status Epilepticus
- First Aid: Lateral position, time seizure, Oβ, do not restrain
- First-Line Tx: Buccal midazolam 0.5 mg/kg or rectal diazepam 0.5 mg/kg; if no response: IV lorazepam 0.1 mg/kg; second-line: levetiracetam or phenobarbital IV; glucose check; LP after stabilization for first episode
95. Croup (Severe)
- First Aid: Keep calm, upright position, humidified Oβ; avoid distressing child
- First-Line Tx: Nebulized epinephrine (1:1000, 0.5 mL/kg, max 5 mL); dexamethasone 0.6 mg/kg PO/IM/IV; heliox; intubate if severe obstruction; admit if epinephrine required
96. Pediatric Meningococcemia
- First Aid: IV access, immediate blood cultures, non-blanching rash = emergency
- First-Line Tx: IV ceftriaxone 100 mg/kg (max 2 g) within minutes of recognition; IV dexamethasone; IV fluids; vasopressors; PICU; prophylaxis for contacts (rifampicin or ciprofloxacin)
97. Intussusception (Pediatric)
- First Aid: IV access, IV fluids, analgesia, NPO
- First-Line Tx: Pneumatic/hydrostatic enema reduction (diagnostic and therapeutic, 80β90% success); surgery if peritonitis, perforation, or failed enema; IV antibiotics; post-reduction observation 24h
π§ PSYCHIATRIC / ENVIRONMENTAL (98β100)
98. Anaphylaxis
- First Aid: Lay flat + legs elevated (unless breathing difficulty), call for help
- First-Line Tx: Epinephrine 0.3β0.5 mg IM (1:1000) anterolateral thigh β IMMEDIATELY; repeat q5β15 min; Oβ; IV access; IV diphenhydramine 50 mg; methylprednisolone 125 mg; IV fluids 1β2 L; salbutamol for bronchospasm; observe 4β6 hours minimum
99. Heat Stroke (Classic/Exertional)
- First Aid: Remove from hot environment, remove clothing, ice packs to axillae/groin/neck
- First-Line Tx: Cold water immersion (most effective) or ice packs; IV cooled saline; target temp <39Β°C within 30 min; intubation if obtunded; treat seizures (benzodiazepines); monitor for rhabdomyolysis, DIC, hepatic failure
100. Near-Drowning / Submersion Injury
- First Aid: Remove from water, spine precautions, CPR if pulseless, lateral decubitus if breathing
- First-Line Tx: Oβ (100% initially); assess for aspiration pneumonia; NIV/CPAP for pulmonary edema; warm if hypothermic (40Β°C heated humidified Oβ, warm IV fluids); continue resuscitation for hypothermic arrest until T >35Β°C; ICU monitoring for delayed ARDS
Quick Reference Summary Table
| # | Condition | Most Critical Immediate Action |
|---|
| 1 | STEMI | Aspirin + activate cath lab |
| 5 | Cardiac Tamponade | Pericardiocentesis |
| 7 | Cardiac Arrest (VF) | Defibrillate immediately |
| 13 | Ischemic Stroke | tPA within 4.5 h / thrombectomy |
| 16 | Status Epilepticus | IV/IM benzodiazepine |
| 17 | Bacterial Meningitis | Antibiotics + dexamethasone STAT |
| 23 | Status Asthmaticus | Salbutamol + IV steroids + Mg |
| 25 | Tension Pneumothorax | Immediate needle decompression |
| 29 | Epiglottitis | Airway β do not examine throat |
| 33 | Polytrauma | ABCDE + damage control resus |
| 40 | Ruptured AAA | Emergent vascular surgery |
| 52 | DKA | IV fluids + insulin + K replacement |
| 55 | Thyroid Storm | PTU + beta-blocker + iodine |
| 59 | Septic Shock | Antibiotics + fluids within 1 h |
| 60 | Necrotizing Fasciitis | Emergent surgical debridement |
| 65 | Paracetamol OD | N-acetylcysteine (NAC) |
| 66 | Opioid OD | Naloxone IM/IV |
| 69 | Organophosphate | Atropine + pralidoxime |
| 70 | CO Poisoning | 100% Oβ / hyperbaric Oβ |
| 82 | Ruptured Ectopic | Emergent surgery |
| 84 | Eclampsia | Magnesium + deliver fetus |
| 86 | PPH | Oxytocin + TXA + uterine massage |
| 89 | Chemical Eye Burn | Irrigate immediately Γ 30 min |
| 98 | Anaphylaxis | Epinephrine IM immediately |
Key Universal Principles Across All ER Cases:
- Airway is always the first priority
- Time is tissue β stroke, STEMI, sepsis, and torsion all have hard time windows
- Two large-bore IVs before anything else in hemodynamic emergencies
- Do not delay antibiotics waiting for cultures in sepsis/meningitis
- Permissive hypotension in uncontrolled hemorrhage until surgical control
- Reverse the reversible β H's and T's in cardiac arrest, toxidrome antidotes
- Call for help early β airway emergencies, trauma, obstetric crises