Orris

Overview of heart disease Heart failure Left-sided heart failure Right-shyperreactivityure Cor pulmonale Congenital heart disease Left-to-right shunts (ASD, VSD, PDA) Right-to-left shunts (tetralogy of Fallot, transposition of the great arteries) Obstructive congenital lesions (aortic coarctation) Atherosclerosis and its pathogenesis Plaque vulnerability and acute plaque change Foam cell formation and atherogenesis Ischemic heart disease Angina pectoris (stable, unstable, variant) Myocardial infarction Coronary artery anatomy and patterns of infarction Morphologic evolution of myocardial infarction over time Reperfusion injury and contraction band necrosis Complications of myocardial infarction Chronic ischemic heart disease Systemic (left-sided) hypertensive heart disease Pulmonary hypertensive heart disease Valvular heart disease Calcific aortic stenosis Mitral valve prolapse Rheumatic fever and rheumatic valvular disease Infective endocarditis Nonbacterial thrombotic endocarditis Libman-Sacks endocarditis Cardiomyopathies Dilated cardiomyopathy Hypertrophic cardiomyopathy Restrictive cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Myocarditis Cardiotoxic drugs Pericardial disease and cardiac tamponade Aneurysms (abdominal and thoracic) Aortic dissection Vasculitis classification by vessel size and mechanism Large vessel vasculitis (giant cell, Takayasu) Medium vessel vasculitis (polyarteritis nodosa, Kawasaki) Small vessel / ANCA-associated vasculitis Thromboangiitis obliterans (Buerger disease) Raynaud phenomenon and disorders of vascular hyperreactivity

Reading File
Finding Sources
Finding Sources
Finding Sources
Finding Sources
Finding Sources
Finding Sources
Reading File
Reading File
Finding Sources
Reading File
Finding Sources
Reading File
Reading File
Reading File
Reading File
Reading File
Reading File
Reading File
Reading File
The comprehensive overview above covers every topic on your list. Here is a brief map of what was covered:
Section 1 - Heart Disease Overview & Heart Failure: Mechanisms of compensation (Frank-Starling, neurohumoral, hypertrophy), left-sided vs. right-sided failure (heart failure cells, nutmeg liver), and cor pulmonale (RV hypertrophy from primary pulmonary disease).
Section 3 - Congenital Heart Disease: Left-to-right shunts (ASD, VSD, PDA) with Eisenmenger progression; right-to-left shunts - Tetralogy of Fallot (4 features from infundibular displacement, boot-shaped heart) and Transposition (aorta from RV, pulmonary from LV, requires shunt for survival); coarctation (infantile vs. adult types, rib notching, Turner syndrome association).
Section 4-5 - Atherosclerosis & IHD: Response-to-injury hypothesis, foam cell formation via scavenger receptor uptake of ox-LDL, vulnerable vs. stable plaques, plaque rupture mechanics. MI pathogenesis, coronary anatomy, the full morphologic timeline table (0 hr to >2 months), reperfusion injury and contraction band necrosis, and all major complications with their timing.
Section 7 - Valvular Disease: Calcific aortic stenosis (tricuspid vs. bicuspid); MVP (myxomatous degeneration); rheumatic fever (Aschoff bodies, Anitschkow cells, Jones criteria, fish-mouth mitral stenosis); IE organisms and Duke criteria; NBTE (hypercoagulable, embologenic); Libman-Sacks (SLE, both surfaces).
Section 8-9 - Cardiomyopathies & Myocarditis: DCM vs. HCM (asymmetric septal hypertrophy, myofiber disarray, sarcomere mutations) vs. RCM (amyloid, Congo red); ARVC (desmosomal protein mutations, fibrofatty RV replacement, epsilon wave); cardiotoxic drugs (doxorubicin free radical mechanism, trastuzumab HER2 pathway).
Section 10-11 - Pericardial Disease & Vascular: Tamponade (Beck's triad, pulsus paradoxus); AAA (infrarenal, rupture risk at >5 cm); thoracic aneurysm (cystic medial degeneration, syphilis); aortic dissection (Stanford A vs. B, management).
Section 12-14 - Vasculitis & Raynaud: Large vessel (GCA with temporal headache/blindness risk; Takayasu with absent upper extremity pulses); medium vessel (PAN - segmental, HBV-associated, no lung; Kawasaki - coronary aneurysms, IVIG+aspirin); small vessel/ANCA (Wegener = c-ANCA, upper+lower airway + GN; MPA = p-ANCA, no granulomas; Churg-Strauss = eosinophilia + asthma); Buerger disease (tobacco, extremity gangrene); Raynaud (primary vs. secondary, scleroderma most important secondary cause).

Generate a comprehensive pathology study guide (PDF or Word document) for exam review

Asking for Preferences
This is a shared conversation. Sign in to Orris to start your own chat.