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Cervical Cerclage in Pregnancy
What is Cervical Cerclage?
A surgical procedure where sutures are placed around the cervix to prevent premature dilation and second-trimester pregnancy loss or preterm birth, primarily used for cervical insufficiency.
Three Types & Their Timing
1. History-Indicated Cerclage (HIC)
Timing: 11–15 weeks (ideally before 14 weeks of gestation)
Placed based purely on obstetric history, before any cervical changes are observed in the current pregnancy.
Indications:
- Singleton gestation with a history of painless cervical dilation leading to second-trimester pregnancy loss
- Prior exam-indicated cerclage
- Prior ultrasound-indicated cerclage with subsequent preterm delivery ≤32 weeks (high recurrence risk)
- ≥3 prior second-trimester losses or early preterm births (strongest RCT evidence)
Note: A prior cerclage alone does not automatically indicate cerclage in the current pregnancy — the underlying indication must be re-evaluated each time.
Transabdominal HIC is recommended (prepregnancy or before 13 weeks) when:
- Prior failed history-indicated transvaginal cerclage with preterm birth <33 weeks
- Little/no accessible cervix vaginally (due to müllerian anomaly or prior cervical surgery)
2. Ultrasound-Indicated Cerclage (UIC)
Timing: Before 24 weeks (16⁰⁄₇ – 23⁶⁄₇ weeks)
Placed when cervical shortening is detected on transvaginal ultrasound in a high-risk patient.
Indications:
- Singleton gestation with prior spontaneous preterm birth (16⁰⁄₇ – 36⁶⁄₇ weeks) AND
- Current transvaginal cervical length <25 mm on second-trimester ultrasound
- No chorioamnionitis, abruption, or other contraindication
Evidence: Meta-analysis of 5 RCTs shows cerclage reduces preterm birth <35 weeks by 30% and perinatal morbidity/mortality by 36% in this group.
For singletons with short cervix but no prior preterm birth: vaginal progesterone is preferred; cerclage is considered only if cervical length <15 mm (limited evidence).
Not recommended in multiple gestations regardless of cervical length.
3. Physical Exam–Indicated Cerclage (PEIC) — "Rescue Cerclage"
Timing: Before 24 weeks (16⁰⁄₇ – 23⁶⁄₇ weeks)
Placed urgently when cervical dilation is found on examination.
Indications:
- Singleton or twin gestation with painless cervical dilation ≥1 cm detected on speculum or digital exam
- No fetal demise, active labor, rupture of membranes, chorioamnionitis, or abruption
Special considerations:
- Amniocentesis should be considered before placement (especially if membranes are visible, cervix ≥2 cm dilated, or ultrasound suggests intra-amniotic infection) to rule out subclinical infection
- Perioperative indomethacin is recommended
- Hospital admission for 12–24 hours post-procedure is standard
Summary Table
| Type | Indication | Timing |
|---|
| History-Indicated (HIC) | Prior 2nd-trimester loss from painless dilation; prior cerclage with PTB ≤32 wks | 11–15 weeks |
| Transabdominal HIC | Failed transvaginal HIC with PTB <33 wks | Pre-pregnancy or <13 weeks |
| Ultrasound-Indicated (UIC) | Prior PTB + current CL <25 mm | 16–24 weeks |
| Physical Exam–Indicated (PEIC) | Painless cervical dilation on exam | Before 24 weeks |
Contraindications to Cerclage
- Active labor
- Ruptured membranes
- Chorioamnionitis
- Placental abruption
- Fetal demise or lethal fetal anomaly
- Gestational age ≥24 weeks (generally)
Important Notes
- Cerclage is not beneficial in multiple gestations for primary prevention
- Continue progesterone therapy even after cerclage placement in patients with prior spontaneous PTB
- Routine bed rest is NOT recommended post-cerclage
- Cerclage is typically removed at 36–37 weeks of gestation
Source: Creasy & Resnik's Maternal-Fetal Medicine: Principles and Practice, Table 38.4 & Chapter 38
A
2025 systematic review (PMID: 40541862) comparing cerclage placement guidelines across societies is the most recent evidence synthesis — worth reviewing for any updates to specific threshold criteria.