What's Covered

Clinical Cases (Questions 1-6):

1. Black discolouration - Anthracosis (carbon pigment deposition)
2. Cervical lymphadenopathy - TB lymphadenitis with Langhans giant cells
3. Raised scar lesion - Keloid vs hypertrophic scar
4. Baby with flat face + heart defects - Down Syndrome (Trisomy 21)
5. HIV/AIDS - CD4 counts, AIDS-defining neoplasms, diagnostic tests
6. Penicillin reaction - Anaphylaxis (Type I hypersensitivity)

Gross Specimens:

• Liver cirrhosis with HCC risk
• Diabetic gangrene (coagulative/dry necrosis)
• Cardiac hypertrophy (LVH)
• GI specimens (appendix/bowel)
• Uterine leiomyoma (fibroid → leiomyosarcoma)
• Squamous cell carcinoma (radiation-induced in radiologist)
• Body builder (physiological hypertrophy)

Microscopy specimens:

• Amyloidosis (Congo red, apple-green birefringence)
• Fatty change / steatosis
• Hyaline degeneration
• Fibrinoid necrosis
• Caseating granuloma (TB)
• Coagulative infarct
• Liquefactive necrosis
• Dystrophic calcification
• Caseous necrosis

The document's embedded images could not be directly analyzed since the assignment images are internal files. If you want me to identify specific gross or microscopy photographs, feel free to share them as image attachments and I will use visual analysis to give precise identifications.