Regional anatomy

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Upper Limb - Regional Anatomy (Exam Study Notes)

Source: Gray's Anatomy for Students

1. Overview and Bones

The upper limb is divided into five regions:
RegionKey Bones
Shoulder girdleClavicle, scapula
Arm (brachium)Humerus
Forearm (antebrachium)Radius (lateral), Ulna (medial)
Wrist (carpus)8 carpal bones
Hand5 metacarpals + 14 phalanges
Mnemonic for carpals (proximal to distal, lateral to medial):
  • Proximal row: Scaphoid, Lunate, Triquetrum, Pisiform
  • Distal row: Trapezium, Trapezoid, Capitate, Hamate
  • "Some Lovers Try Positions That They Can't Handle"

2. Brachial Plexus

The most tested topic in upper limb anatomy.
Roots: Anterior rami of C5, C6, C7, C8, T1 - pass between anterior and middle scalene muscles, posterior to subclavian artery.
Brachial plexus - origins from C5 to T1, showing Roots, Trunks, Divisions, and Cords
Schematic (Roots → Trunks → Divisions → Cords → Branches):
Brachial plexus schematic showing how Superior, Middle, and Inferior trunks divide into Anterior/Posterior divisions forming Lateral, Posterior, and Medial cords
Trunks:
  • Superior trunk = C5 + C6
  • Middle trunk = C7 alone
  • Inferior trunk = C8 + T1
Divisions: Each trunk divides into anterior and posterior divisions.
Cords (named by position relative to the 2nd part of the axillary artery):
  • Lateral cord = anterior divisions of Superior + Middle trunks
  • Medial cord = anterior division of Inferior trunk
  • Posterior cord = all three posterior divisions
Key terminal branches:
CordTerminal NervesKey Functions
LateralMusculocutaneous nerve, lateral root of median nerveArm flexors; forearm sensation
MedialUlnar nerve, medial root of median nerveIntrinsic hand muscles; ring/little fingers
PosteriorAxillary nerve, radial nerveDeltoid; all posterior compartment muscles
The "M" over the axillary artery: The musculocutaneous nerve, lateral root of median nerve, median nerve, medial root of median nerve, and ulnar nerve form a visible M-shape over the 3rd part of the axillary artery - a landmark for identifying plexus components in surgery.

3. Axilla

The axilla is the gateway to the upper limb - a pyramidal space formed by the clavicle, scapula, upper thoracic wall, and humerus. It has four walls, an inlet (continuous with the neck), and a floor.
All major structures passing into/out of the upper limb pass through the axilla, including the axillary artery, axillary vein, and brachial plexus.
Key spaces in the posterior axillary wall:
  • Quadrangular space: transmits axillary nerve + posterior circumflex humeral artery
  • Triangular space: transmits circumflex scapular artery
  • Triangular interval: transmits radial nerve + profunda brachii artery into the arm

4. Shoulder Region

Glenohumeral joint - ball-and-socket synovial joint, most mobile in body; least stable.
Rotator cuff muscles (SITS):
MuscleActionNerve
SupraspinatusAbduction (initiates 0-15°)Suprascapular (C5, C6)
InfraspinatusLateral rotationSuprascapular (C5, C6)
Teres minorLateral rotationAxillary (C5, C6)
SubscapularisMedial rotationSubscapular nerves (C5, C6)
Axillary nerve exits the quadrangular space and innervates the deltoid and teres minor. It wraps around the surgical neck of the humerus - vulnerable in neck-of-humerus fractures and shoulder dislocations.

5. Arm (Humerus Region)

Two fascial compartments separated by medial and lateral intermuscular septa:
Anterior (flexor) compartment:
  • Muscles: Biceps brachii, brachialis, coracobrachialis
  • Nerve: Musculocutaneous nerve (C5, C6, C7)
  • Biceps: long head from supraglenoid tubercle, short head from coracoid process → flexion + supination
  • Brachialis: main elbow flexor (deep to biceps)
Posterior (extensor) compartment:
  • Muscle: Triceps brachii (3 heads: long, medial, lateral)
  • Nerve: Radial nerve (C7, C8)
  • Radial nerve travels in the spiral groove (radial groove) of the humerus - vulnerable in mid-shaft humeral fractures → wrist drop (inability to extend wrist/fingers)
Main artery: Brachial artery (continuation of axillary) runs in the anterior compartment medial to the biceps tendon, bifurcating at the cubital fossa into radial and ulnar arteries.

6. Elbow Joint

  • Hinge-type synovial joint allowing flexion/extension; also incorporates proximal radioulnar joint for pronation/supination
  • Bones: Humerus (trochlea + capitulum) articulates with Ulna (trochlear notch) and Radius (head)
  • Anular ligament of radius holds the radial head against the radial notch of the ulna; important in pronation/supination
  • Fat pads lie over the olecranon, coronoid, and radial fossae - displacement ("sail sign") on X-ray indicates intra-articular effusion/fracture
  • Medial (ulnar) collateral ligament & Lateral (radial) collateral ligament stabilize the joint

7. Forearm

Two compartments:

Anterior (Flexor) Compartment

Three layers, all mainly innervated by median nerve (except flexor carpi ulnaris + medial half of flexor digitorum profundus → ulnar nerve):
LayerMuscles
SuperficialPronator teres, Flexor carpi radialis, Palmaris longus, Flexor carpi ulnaris
IntermediateFlexor digitorum superficialis
DeepFlexor digitorum profundus, Flexor pollicis longus, Pronator quadratus

Posterior (Extensor) Compartment

All innervated by radial nerve (deep branch / posterior interosseous nerve):
LayerMuscles
SuperficialBrachioradialis, Extensor carpi radialis longus, ECRB, Extensor digitorum, Extensor digiti minimi, Extensor carpi ulnaris
DeepAbductor pollicis longus, Extensor pollicis brevis, Extensor pollicis longus, Extensor indicis
Note: Brachioradialis is innervated by the radial nerve before it divides (C5, C6) - flexes the elbow when forearm is in mid-pronation.

8. Carpal Tunnel & Wrist

The carpal tunnel is formed by the carpal bones posteriorly and the flexor retinaculum anteriorly.
Contents of the carpal tunnel (9 tendons + 1 nerve):
  • Flexor digitorum superficialis (4 tendons)
  • Flexor digitorum profundus (4 tendons)
  • Flexor pollicis longus (1 tendon)
  • Median nerve
The ulnar nerve and artery pass OUTSIDE the carpal tunnel, through Guyon's canal.
Carpal tunnel syndrome: Compression of the median nerve → pain/paresthesia in the lateral 3½ digits, thenar wasting, weak opposition of thumb.

9. Hand

Palmar Arches

ArchSourceLocation
Superficial palmar archMainly ulnar artery + radial superficial branchSuperficial to long flexor tendons
Deep palmar archMainly radial artery + ulnar deep branchDeep to long flexor tendons, over metacarpals
Allen's test checks adequacy of anastomosis between radial and ulnar arteries.

Nerves of the Hand

NerveSensoryMotor
MedianLateral 3½ fingers (palmar), distal dorsal tips of these fingersThenar muscles (LOAF: Lateral 2 lumbricals, Opponens pollicis, Abductor pollicis brevis, Flexor pollicis brevis)
UlnarMedial 1½ fingers (both surfaces)All other intrinsic hand muscles (interossei, medial 2 lumbricals, hypothenar, adductor pollicis)
Radial (superficial branch)Dorsum of lateral 3½ fingers (proximal)None in hand

Thenar vs. Hypothenar Eminences

  • Thenar (base of thumb): median nerve - abductor pollicis brevis, opponens pollicis, flexor pollicis brevis
  • Hypothenar (base of little finger): ulnar nerve - abductor digiti minimi, flexor digiti minimi, opponens digiti minimi

Anatomical Snuffbox

  • Lateral border: Tendons of APL + EPB
  • Medial border: Tendon of EPL
  • Floor: Scaphoid + trapezium
  • Contents: Radial artery (pulse palpable here), terminal branches of superficial radial nerve, origin of cephalic vein
  • Clinical: Tenderness in snuffbox = scaphoid fracture until proven otherwise

10. Key Clinical Nerve Injuries

NerveInjury SiteDeformityMuscle Loss
Radial nerveSpiral groove (mid-shaft humerus)Wrist dropCannot extend wrist/fingers
Median nerveCarpal tunnel"Ape hand" (thenar wasting)No thumb opposition
Ulnar nerveMedial epicondyle (elbow)"Claw hand" (medial 2 fingers)Intrinsic hand muscles
Axillary nerveSurgical neck of humerusRounded shoulderDeltoid paralysis
Musculocutaneous nerveAxillaWeak elbow flexionBiceps/brachialis
Brachial plexus injuries:
  • Erb's palsy (upper trunk C5-C6): "Waiter's tip" deformity - arm adducted, medially rotated, forearm pronated. Caused by forceful neck-shoulder separation (difficult delivery, motorcycle fall)
  • Klumpke's palsy (lower trunk C8-T1): Intrinsic hand muscle paralysis + claw hand. May include Horner syndrome if T1 sympathetic fibers involved

11. Superficial Veins

VeinCourse
Cephalic veinOriginates from lateral dorsal venous network → anatomical snuffbox → lateral forearm → deltopectoral groove → drains into axillary vein
Basilic veinMedial dorsal network → medial forearm → pierces deep fascia → drains into brachial vein → forms axillary vein
Median cubital veinConnects cephalic and basilic at the cubital fossa - standard IV access site

Quick-Reference Summary Table

RegionKey NerveKey ArteryHigh-Yield Clinical
ShoulderAxillary (C5-C6)Posterior circumflex humeralRotator cuff tears, shoulder dislocation
ArmMusculocutaneous (ant), Radial (post)BrachialRadial nerve palsy - wrist drop
ElbowMedian, Radial, UlnarBrachial bifurcationLateral epicondylitis ("tennis elbow")
ForearmMedian (ant), Radial (post), Ulnar (FCU, FDP)Radial + UlnarPronator syndrome
Wrist/Carpal tunnelMedianRadial arteryCarpal tunnel syndrome
HandMedian (lateral), Ulnar (medial)Superficial + deep palmar archesScaphoid fracture, dupuytren's, mallet finger

Gray's Anatomy for Students, Chapter 7 - Upper Limb
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