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Upper Limb - Regional Anatomy (Exam Study Notes)
Source: Gray's Anatomy for Students
1. Overview and Bones
The upper limb is divided into five regions:
| Region | Key Bones |
|---|
| Shoulder girdle | Clavicle, scapula |
| Arm (brachium) | Humerus |
| Forearm (antebrachium) | Radius (lateral), Ulna (medial) |
| Wrist (carpus) | 8 carpal bones |
| Hand | 5 metacarpals + 14 phalanges |
Mnemonic for carpals (proximal to distal, lateral to medial):
- Proximal row: Scaphoid, Lunate, Triquetrum, Pisiform
- Distal row: Trapezium, Trapezoid, Capitate, Hamate
- "Some Lovers Try Positions That They Can't Handle"
2. Brachial Plexus
The most tested topic in upper limb anatomy.
Roots: Anterior rami of C5, C6, C7, C8, T1 - pass between anterior and middle scalene muscles, posterior to subclavian artery.
Schematic (Roots → Trunks → Divisions → Cords → Branches):
Trunks:
- Superior trunk = C5 + C6
- Middle trunk = C7 alone
- Inferior trunk = C8 + T1
Divisions: Each trunk divides into anterior and posterior divisions.
Cords (named by position relative to the 2nd part of the axillary artery):
- Lateral cord = anterior divisions of Superior + Middle trunks
- Medial cord = anterior division of Inferior trunk
- Posterior cord = all three posterior divisions
Key terminal branches:
| Cord | Terminal Nerves | Key Functions |
|---|
| Lateral | Musculocutaneous nerve, lateral root of median nerve | Arm flexors; forearm sensation |
| Medial | Ulnar nerve, medial root of median nerve | Intrinsic hand muscles; ring/little fingers |
| Posterior | Axillary nerve, radial nerve | Deltoid; all posterior compartment muscles |
The "M" over the axillary artery: The musculocutaneous nerve, lateral root of median nerve, median nerve, medial root of median nerve, and ulnar nerve form a visible M-shape over the 3rd part of the axillary artery - a landmark for identifying plexus components in surgery.
3. Axilla
The axilla is the gateway to the upper limb - a pyramidal space formed by the clavicle, scapula, upper thoracic wall, and humerus. It has four walls, an inlet (continuous with the neck), and a floor.
All major structures passing into/out of the upper limb pass through the axilla, including the axillary artery, axillary vein, and brachial plexus.
Key spaces in the posterior axillary wall:
- Quadrangular space: transmits axillary nerve + posterior circumflex humeral artery
- Triangular space: transmits circumflex scapular artery
- Triangular interval: transmits radial nerve + profunda brachii artery into the arm
4. Shoulder Region
Glenohumeral joint - ball-and-socket synovial joint, most mobile in body; least stable.
Rotator cuff muscles (SITS):
| Muscle | Action | Nerve |
|---|
| Supraspinatus | Abduction (initiates 0-15°) | Suprascapular (C5, C6) |
| Infraspinatus | Lateral rotation | Suprascapular (C5, C6) |
| Teres minor | Lateral rotation | Axillary (C5, C6) |
| Subscapularis | Medial rotation | Subscapular nerves (C5, C6) |
Axillary nerve exits the quadrangular space and innervates the deltoid and teres minor. It wraps around the surgical neck of the humerus - vulnerable in neck-of-humerus fractures and shoulder dislocations.
5. Arm (Humerus Region)
Two fascial compartments separated by medial and lateral intermuscular septa:
Anterior (flexor) compartment:
- Muscles: Biceps brachii, brachialis, coracobrachialis
- Nerve: Musculocutaneous nerve (C5, C6, C7)
- Biceps: long head from supraglenoid tubercle, short head from coracoid process → flexion + supination
- Brachialis: main elbow flexor (deep to biceps)
Posterior (extensor) compartment:
- Muscle: Triceps brachii (3 heads: long, medial, lateral)
- Nerve: Radial nerve (C7, C8)
- Radial nerve travels in the spiral groove (radial groove) of the humerus - vulnerable in mid-shaft humeral fractures → wrist drop (inability to extend wrist/fingers)
Main artery: Brachial artery (continuation of axillary) runs in the anterior compartment medial to the biceps tendon, bifurcating at the cubital fossa into radial and ulnar arteries.
6. Elbow Joint
- Hinge-type synovial joint allowing flexion/extension; also incorporates proximal radioulnar joint for pronation/supination
- Bones: Humerus (trochlea + capitulum) articulates with Ulna (trochlear notch) and Radius (head)
- Anular ligament of radius holds the radial head against the radial notch of the ulna; important in pronation/supination
- Fat pads lie over the olecranon, coronoid, and radial fossae - displacement ("sail sign") on X-ray indicates intra-articular effusion/fracture
- Medial (ulnar) collateral ligament & Lateral (radial) collateral ligament stabilize the joint
7. Forearm
Two compartments:
Anterior (Flexor) Compartment
Three layers, all mainly innervated by median nerve (except flexor carpi ulnaris + medial half of flexor digitorum profundus → ulnar nerve):
| Layer | Muscles |
|---|
| Superficial | Pronator teres, Flexor carpi radialis, Palmaris longus, Flexor carpi ulnaris |
| Intermediate | Flexor digitorum superficialis |
| Deep | Flexor digitorum profundus, Flexor pollicis longus, Pronator quadratus |
Posterior (Extensor) Compartment
All innervated by radial nerve (deep branch / posterior interosseous nerve):
| Layer | Muscles |
|---|
| Superficial | Brachioradialis, Extensor carpi radialis longus, ECRB, Extensor digitorum, Extensor digiti minimi, Extensor carpi ulnaris |
| Deep | Abductor pollicis longus, Extensor pollicis brevis, Extensor pollicis longus, Extensor indicis |
Note: Brachioradialis is innervated by the radial nerve before it divides (C5, C6) - flexes the elbow when forearm is in mid-pronation.
8. Carpal Tunnel & Wrist
The carpal tunnel is formed by the carpal bones posteriorly and the flexor retinaculum anteriorly.
Contents of the carpal tunnel (9 tendons + 1 nerve):
- Flexor digitorum superficialis (4 tendons)
- Flexor digitorum profundus (4 tendons)
- Flexor pollicis longus (1 tendon)
- Median nerve
The ulnar nerve and artery pass OUTSIDE the carpal tunnel, through Guyon's canal.
Carpal tunnel syndrome: Compression of the median nerve → pain/paresthesia in the lateral 3½ digits, thenar wasting, weak opposition of thumb.
9. Hand
Palmar Arches
| Arch | Source | Location |
|---|
| Superficial palmar arch | Mainly ulnar artery + radial superficial branch | Superficial to long flexor tendons |
| Deep palmar arch | Mainly radial artery + ulnar deep branch | Deep to long flexor tendons, over metacarpals |
Allen's test checks adequacy of anastomosis between radial and ulnar arteries.
Nerves of the Hand
| Nerve | Sensory | Motor |
|---|
| Median | Lateral 3½ fingers (palmar), distal dorsal tips of these fingers | Thenar muscles (LOAF: Lateral 2 lumbricals, Opponens pollicis, Abductor pollicis brevis, Flexor pollicis brevis) |
| Ulnar | Medial 1½ fingers (both surfaces) | All other intrinsic hand muscles (interossei, medial 2 lumbricals, hypothenar, adductor pollicis) |
| Radial (superficial branch) | Dorsum of lateral 3½ fingers (proximal) | None in hand |
Thenar vs. Hypothenar Eminences
- Thenar (base of thumb): median nerve - abductor pollicis brevis, opponens pollicis, flexor pollicis brevis
- Hypothenar (base of little finger): ulnar nerve - abductor digiti minimi, flexor digiti minimi, opponens digiti minimi
Anatomical Snuffbox
- Lateral border: Tendons of APL + EPB
- Medial border: Tendon of EPL
- Floor: Scaphoid + trapezium
- Contents: Radial artery (pulse palpable here), terminal branches of superficial radial nerve, origin of cephalic vein
- Clinical: Tenderness in snuffbox = scaphoid fracture until proven otherwise
10. Key Clinical Nerve Injuries
| Nerve | Injury Site | Deformity | Muscle Loss |
|---|
| Radial nerve | Spiral groove (mid-shaft humerus) | Wrist drop | Cannot extend wrist/fingers |
| Median nerve | Carpal tunnel | "Ape hand" (thenar wasting) | No thumb opposition |
| Ulnar nerve | Medial epicondyle (elbow) | "Claw hand" (medial 2 fingers) | Intrinsic hand muscles |
| Axillary nerve | Surgical neck of humerus | Rounded shoulder | Deltoid paralysis |
| Musculocutaneous nerve | Axilla | Weak elbow flexion | Biceps/brachialis |
Brachial plexus injuries:
- Erb's palsy (upper trunk C5-C6): "Waiter's tip" deformity - arm adducted, medially rotated, forearm pronated. Caused by forceful neck-shoulder separation (difficult delivery, motorcycle fall)
- Klumpke's palsy (lower trunk C8-T1): Intrinsic hand muscle paralysis + claw hand. May include Horner syndrome if T1 sympathetic fibers involved
11. Superficial Veins
| Vein | Course |
|---|
| Cephalic vein | Originates from lateral dorsal venous network → anatomical snuffbox → lateral forearm → deltopectoral groove → drains into axillary vein |
| Basilic vein | Medial dorsal network → medial forearm → pierces deep fascia → drains into brachial vein → forms axillary vein |
| Median cubital vein | Connects cephalic and basilic at the cubital fossa - standard IV access site |
Quick-Reference Summary Table
| Region | Key Nerve | Key Artery | High-Yield Clinical |
|---|
| Shoulder | Axillary (C5-C6) | Posterior circumflex humeral | Rotator cuff tears, shoulder dislocation |
| Arm | Musculocutaneous (ant), Radial (post) | Brachial | Radial nerve palsy - wrist drop |
| Elbow | Median, Radial, Ulnar | Brachial bifurcation | Lateral epicondylitis ("tennis elbow") |
| Forearm | Median (ant), Radial (post), Ulnar (FCU, FDP) | Radial + Ulnar | Pronator syndrome |
| Wrist/Carpal tunnel | Median | Radial artery | Carpal tunnel syndrome |
| Hand | Median (lateral), Ulnar (medial) | Superficial + deep palmar arches | Scaphoid fracture, dupuytren's, mallet finger |
Gray's Anatomy for Students, Chapter 7 - Upper Limb