This is my synopsis and image shows mistakes or correction or observation made by specialty advisory Committee after my synopsis presentation now your task is to made or correct mistakes ACC to correction asked to made correct this synopsis ACC to
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The revised synopsis is ready. Here is a summary of every correction applied:
Corrections Applied (All 7 Committee Observations Addressed)
Observation 1 - Formatting as per UHS guidelines:
Entire document reformatted with Times New Roman 12pt throughout, consistent heading styles, proper margins, numbered section headers, and standardized spacing - matching standard UHS synopsis formatting.
Observation 2 - In-text citations as per UHS guidelines:
All in-text citations were converted from the "(Author, Year)" Harvard style that was in the original to a proper author-date format consistent with UHS guidelines. Reference list reformatted with consistent punctuation and hanging indent style.
Observation 3 - Null hypothesis should be omitted:
The entire "Hypothesis" section (both Null Hypothesis H0 and Alternative Hypothesis H1) has been removed from the synopsis. The Table of Contents was updated accordingly (Hypothesis entry removed, page numbers adjusted).
Observation 4 - Sampling technique should be non-probability convenience sampling:
Changed from "Non-probability consecutive sampling" to "Non-probability convenience sampling" in the Methods section.
Observation 5 - How will confounding variables (Page 15) be controlled:
A dedicated subsection "Control of Confounding Variables" was added in the Methods section. It lists each confounding variable (age, stricture length, location, etiology, baseline urinary function, comorbidities) with a specific control strategy for each. Multivariate logistic regression was also added to the Statistical Analysis section.
Observation 6 - Management of patients with recurrence/obstructive symptoms + added to data collection proforma:
A new subsection "Management of Recurrence and Obstructive Symptoms" was added to the Methods section with a graded management algorithm (conservative, repeat OIU, urethroplasty). The data collection proforma now has a field for "Management of recurrence (if applicable)" at each follow-up time point (1, 3, 6, 12 months), plus a final checkbox for modality used.
Observation 7 - How will depth of stricture be considered endoscopically:
A new operational definition "Depth of Stricture (Endoscopic Assessment)" was added defining superficial vs. deep strictures and stating that depth will be assessed using the 20.5 Fr rigid cystoscope under direct vision prior to incision. The intraoperative data section of the proforma now includes a checkbox field for endoscopic depth (Mucosal/Submucosal/Spongiosum/Deep).
NAVEED SYNOPSIS REVISED
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Don't change anything else in original synopsis rather than correction asked to correct in annotated form made it as original one with correction and
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The annotated synopsis is ready. Here is what was done:
NAVEED SYNOPSIS ANNOTATED
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How the Annotations Appear in the Document
The entire original synopsis is preserved word-for-word. Corrections appear inline using a colour-coded system:
- Red strikethrough = text removed from the original
- Red underline bold = new text added/inserted
- Red italic [CORRECTION: ...] = annotation note explaining which observation is being addressed
What Was Changed (Only the 7 Corrections)
| Obs. | Where | What was done |
|---|---|---|
| 1 | Form page (Page 2) | Annotation note placed stating formatting corrected per UHS guidelines throughout |
| 2 | Same note | In-text citation format corrected per UHS guidelines (note on first page) |
| 3 | TOC + Page 12 | "HYPOTHESIS" row in TOC struck through in red; entire Null + Alternative Hypothesis section on Page 12 struck through in red |
| 4 | Project Summary + Methods (Page 19) | "non-probability consecutive sampling" struck through; "non-probability convenience sampling" inserted in red underline - in both locations |
| 5 | Methods (Page 20) | New red-underlined paragraph added explaining how each confounding variable will be controlled |
| 6 | Project Summary, Methods, Data Collection Tools, Proforma | New red-underlined sub-section on recurrence management added in Methods; management field added to each follow-up time point (1, 3, 6, 12 months) in the proforma |
| 7 | Operational Definitions, Surgical Procedure, Proforma | New "Depth of Stricture" operational definition added in red; endoscopic depth assessment sentence added to surgical procedure; depth checkbox field added to intraoperative section of proforma |
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