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Section 7, miscellaneous bacterial infections, 179 chapter nocardia is 180 at mycosis, 181 peoples disease, 182 infections due to mixed aerobic organisms. Section 8 micro bacterial diseases chapter number 183, tuberculosis 184 x 185 non-tuberculous bacterial infections, 186 antimicrobial anti Mico bacterial agents, section 9, Phairo diseases, 187, syphilis 188, hematosis 189 la pyrosis, 190 lapsing fever, 191 lines disease section 10 disease is caused by cricket, CA micro plasma and club idea. Chapter number 192 cricket CL is 193 infections due to mycoplasma 194 loml disease section number 11 viral diseases, general considerations, 195 principles of medical virology, 196 anti-viral haemotherapy, excluding antiretroviral drugs. These are the chapters from Harrisons 22nd edition teach me in detail about these topics.

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Here is your complete teaching guide - all chapters covered in detail directly from Harrison's Principles of Internal Medicine, 22nd Edition (2025). Here is a quick orientation of what was covered:

What Was Covered

Section 7 - Miscellaneous Bacterial Infections:
  • Ch. 179 - Nocardia: Weakly acid-fast, TMP-SMX treatment, always image the brain
  • Ch. 180 - Actinomycosis: Sulfur granules, penicillin x 12 months, IUD → pelvic actinomycosis
  • Ch. 181 - Whipple's Disease: PAS+ macrophages in intestinal biopsy, oculomasticatory myorhythmia is pathognomonic, treat with ceftriaxone then TMP-SMX
  • Ch. 182 - Mixed Aerobic-Anaerobic Infections: B. fragilis, necrotizing fasciitis, aspiration pneumonia, bacterial vaginosis
Section 8 - Mycobacterial Diseases:
  • Ch. 183 - Tuberculosis: Full pathogenesis, diagnosis (IGRA, GeneXpert), LTBI and active TB regimens from Harrison's Tables 186-1 and 186-2, drug side effects
  • Ch. 184 - Leprosy: Ridley-Jopling classification, WHO PB/MB, MDT regimens, Types 1 and 2 reactions
  • Ch. 185 - NTM: Runyon classification, MAC, M. marinum, M. ulcerans, M. abscessus
  • Ch. 186 - Antimycobacterial Agents: Mechanism and toxicity of all first- and second-line drugs, MDR/XDR definitions, BPaL regimen
Section 9 - Spirochetal Diseases:
  • Ch. 187 - Syphilis: All stages, congenital syphilis, Argyll Robertson pupil, VDRL vs FTA-ABS, benzathine PCN treatment, Jarisch-Herxheimer reaction
  • Ch. 188 - Endemic Treponematoses: Yaws, bejel, pinta - comparison table
  • Ch. 189 - Leptospirosis: Conjunctival suffusion, Weil's disease, MAT, treatment table from Harrison's
  • Ch. 190 - Relapsing Fever: LBRF vs STRF vs HTRF, antigenic variation, blood smear diagnosis, doxycycline
  • Ch. 191 - Lyme Disease: EM rash, stages, two-tier serology, treatment by stage
Section 10 - Rickettsiae, Mycoplasma, Chlamydia:
  • Ch. 192 - Rickettsial Diseases: RMSF, Typhus (epidemic/endemic/scrub), Ehrlichioses (HME/HGA - morulae), Q fever
  • Ch. 193 - Mycoplasma Infections: M. pneumoniae (cold agglutinins, atypical pneumonia, azithromycin), urogenital mycoplasmas
  • Ch. 194 - Legionella: Hyponatremia, urinary antigen test, BCYE culture, levofloxacin
Section 11 - Viral Diseases:
  • Ch. 195 - Medical Virology: Virus structure, genome types, replication steps, immune responses (innate PRRs - TLR7/8/3, RIG-I, cGAS; adaptive - CD4/CD8/B cells), viral evolution, PAIS/Long COVID
  • Ch. 196 - Antiviral Chemotherapy: Acyclovir mechanism (viral TK), valacyclovir, ganciclovir (CMV), foscarnet (TK-independent), neuraminidase inhibitors, baloxavir, ribavirin, Paxlovid (nirmatrelvir/ritonavir), remdesivir
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