Here is a comprehensive, step-by-step guide to performing a sensory examination, drawn from Adams and Victor's Principles of Neurology (12th Edition) and Harrison's Principles of Internal Medicine (22nd Edition).
Sensory Examination — Step-by-Step Guide
Before You Begin: General Principles
- Question the patient first — Ask about any changes in sensation: numbness, tingling, burning, "dead" feeling, pins and needles, or unusual sensory experiences. Patients may confuse weakness with numbness.
- Explain the procedure simply — Tell the patient what you are doing in plain terms. Instruct them to say "yes" or "sharp" when they feel something rather than answering "Do you feel that?" each time — this avoids suggestion.
- Eyes closed — The patient should keep their eyes closed (or look away) throughout the examination to prevent visual cueing.
- Do not over-fatigue the patient — Avoid prolonged testing in a tired patient; results become unreliable.
- Compare both sides — Always test symmetrical areas on both sides of the body.
- Proceed from abnormal to normal — It is easier for the patient to identify the boundary of a numb area when you move from the reduced-sensation zone toward the normal area.
- Scope of testing — In a patient with no sensory complaints: a brief screen (vibration, position sense, pinprick in hands and feet + Romberg) is sufficient. In a patient with sensory symptoms or signs: full testing of all modalities is required.
The Five Primary Sensory Modalities
STEP 1 — Light Touch
How to test:
- Use a wisp of cotton, a tissue, or light fingertip touch.
- Demonstrate the sensation first on a normal area of skin so the patient knows what to expect.
- Ask the patient (eyes closed) to say "yes" each time they feel a touch.
- Touch various areas, including suspected abnormal regions.
- Apply a moving stimulus — patients are more sensitive to a moving touch than a stationary one.
- On calloused skin (palms, soles), a slightly firmer stimulus is needed. On hair-covered skin, a lighter touch suffices due to rich nerve endings around hair follicles.
- Avoid testing only on hairy skin due to abundant sensory endings.
What you are testing: Large myelinated fibers → posterior columns (lemniscal pathway)
STEP 2 — Pain Sensation (Superficial)
How to test:
- Use a clean, new pin (discarded after each patient).
- Ask the patient (eyes closed) to focus on the pricking or unpleasant quality — not just the touch or pressure.
- Compare symmetrical areas of the body, proximal to distal.
- If an area of hyalgesia (reduced pain) is found, map it by moving radially outward from the most hyalgesic point.
- Avoid repeated pinpricks in a small area — this causes temporal summation and can mask subtle hyalgesia.
- If overinterpretation is suspected, switch to warm/cold discrimination as a more objective alternative.
What you are testing: Small A-δ and C fibers → spinothalamic tract (contralateral)
STEP 3 — Temperature Sensation
How to test:
- Quick method: Rub one side of a tuning fork briskly against your palm to warm it. Apply the warm and cool sides alternately to the patient's skin — ask "which is cooler/warmer?"
- Formal method: Use two stoppered test tubes — one with warm water (~45°C) and one with cold (~20°C). Apply the side of each tube to the skin for a few seconds; ask whether the object feels "less hot" or "less cold" compared to a normal area.
- Alternatively, a metal tuning fork at room temperature can test cold; warmed metal can test warmth.
- Both cold AND warmth should be tested as different receptors respond to each.
What you are testing: Small fibers → spinothalamic tract (contralateral)
STEP 4 — Vibration Sense
How to test:
- Use a 128-Hz tuning fork.
- Strike the fork to set it vibrating, then apply the base (handle end) to a bony prominence, beginning distally:
- Feet: dorsal surface of the distal phalanx of the big toe, then the medial and lateral malleoli
- Hands: dorsal surface of the distal phalanx of the index finger
- Ask the patient to say when they feel the vibration begin, and when it stops.
- The examiner places their own finger on the opposite side of the joint to compare their own vibration threshold to the patient's — a useful control.
- If abnormalities are found distally, move to more proximal bony points (wrist, elbow, knee, hip, spine).
What you are testing: Large myelinated fibers, especially Pacinian corpuscles → posterior columns (ipsilateral)
STEP 5 — Joint Position Sense (Proprioception)
How to test:
- Start with the distal interphalangeal (DIP) joint of the great toe or index finger.
- Grasp the digit at the sides (not top and bottom), perpendicular to the plane of movement. Stabilize more proximal joints.
- Move the digit passively up or down by small increments (1–2 mm excursions can normally be detected).
- Ask the patient to say "up" or "down" with each movement (eyes closed).
- If errors occur distally, test progressively more proximal joints (ankle, knee, wrist, elbow, shoulder).
- A useful proximal test: Ask the patient to extend both arms and bring their index fingers together with eyes closed. Normal individuals achieve this with errors of ≤1 cm.
What you are testing: Muscle spindles, joint capsule receptors, Golgi tendon organs → posterior columns (ipsilateral)
STEP 6 — The Romberg Test (Proprioception Screening)
How to perform:
- Ask the patient to stand with feet as close together as needed to maintain balance while eyes are open.
- Then ask them to close their eyes.
- A positive Romberg (loss of balance with eyes closed) indicates impaired proprioception.
A Romberg test primarily reveals a posterior column or peripheral proprioceptive deficit — cerebellar ataxia, by contrast, is present even with eyes open.
STEP 7 — Cortical (Discriminative) Sensation
These tests require intact primary sensation. They evaluate parietal lobe integration. Always compare both sides.
a) Two-Point Discrimination
- Use calipers set at various widths (2 mm to several cm).
- Apply two points simultaneously to the test site.
- On fingertips, normal individuals distinguish two points ≥3 mm apart as separate.
- Inability = impaired parietal cortex function.
b) Touch Localization
- Apply light pressure briefly with fingertip or cotton wool.
- Ask the patient (eyes closed) to point to where they were touched.
- Errors suggest a parietal lesion.
c) Bilateral Simultaneous Stimulation (Extinction)
- Lightly touch one or both hands simultaneously.
- Ask the patient (eyes closed) to identify where they are being touched.
- If the patient consistently fails to perceive the stimulus on one side when both sides are touched simultaneously → sensory extinction/neglect, suggesting a contralateral parietal lobe lesion.
d) Graphesthesia
- With the patient's eyes closed, trace a number or letter on the palm of their hand using your fingertip (letters should be >4 cm; on the fingertip, 1 cm numbers can normally be detected).
- Ask the patient to identify it.
- Inability = agraphesthesia — a sign of parietal cortex dysfunction.
e) Stereognosis
- Place a common object (key, coin, paper clip) in the patient's hand with eyes closed.
- Ask them to identify it by feel (shape, texture, size).
- Normal: can distinguish a dime from a penny, a nickel from a quarter.
- Inability = astereognosis — implies contralateral parietal lobe or thalamocortical pathway lesion.
Dermatomal Reference Map
Summary Table
| Modality | Tool | Pathway | Clinical Significance |
|---|
| Light touch | Cotton wisp / finger | Posterior columns (and spinothalamic) | Peripheral neuropathy, posterior column disease |
| Pain (pinprick) | New pin | Spinothalamic (contralateral) | Syringomyelia, Brown-Séquard, peripheral neuropathy |
| Temperature | Test tubes / tuning fork | Spinothalamic (contralateral) | Small-fiber neuropathy, syringomyelia |
| Vibration | 128-Hz tuning fork | Posterior columns (ipsilateral) | B12 deficiency, tabes dorsalis, peripheral neuropathy |
| Joint position | Passive digit movement | Posterior columns (ipsilateral) | Proprioceptive ataxia, posterior column lesions |
| Romberg | Standing with eyes closed | Posterior columns / vestibular | Sensory vs. cerebellar ataxia |
| Two-point discrimination | Calipers | Parietal cortex | Parietal lobe lesion |
| Graphesthesia | Fingertip on palm | Parietal cortex | Agraphesthesia in parietal lesions |
| Stereognosis | Object in hand | Parietal cortex | Astereognosis in parietal/thalamocortical lesions |
Special Notes
- Effect of age: Vibration sense is the first to decline with aging, followed by proprioception and touch — especially in the feet. Do not over-attribute sensory loss to aging without ruling out treatable causes.
- Uncooperative patient: Reduce testing to observing withdrawal responses to noxious stimuli (pinch), and use balance/gait to infer proprioceptive function.
- Spinal cord lesions: Test all modalities, look for a sensory level, and compare root/dermatomal distributions.
- Cortical lesions: Screen primary modalities first — cortical sensory tests are only valid when primary sensation is intact.
- Recording: Document findings in narrative form or shade affected regions on a body diagram.
Sources: Adams and Victor's Principles of Neurology, 12th Edition | Harrison's Principles of Internal Medicine, 22nd Edition