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Explain uses
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Finding Sources
Searching PubMed
"antioxidants"[MeSH Terms] AND "male infertility"
Diomegox+ is an antioxidant multinutrient supplement (a nutraceutical), not a drug. The label says it is "not intended to diagnose, treat, cure or prevent any diseases," and it lists no specific indication. The ingredient mix is the kind sold to reduce oxidative stress. Products like this are most often marketed for male fertility and sperm quality, and sometimes for general antioxidant, cardiovascular or skin support. Confirm the intended purpose with the prescriber or the marketer.
What each ingredient does (amount per tablet)
| Ingredient | Amount | Main role |
|---|---|---|
| Coenzyme Q10 | 100 mg | Part of the mitochondrial electron transport chain, so it supports cellular energy production. It is also a strong antioxidant. |
| Selenium | 30 mcg | Needed for glutathione peroxidase, which removes peroxides. Also supports thyroid enzymes. |
| Zinc | 12 mg | Cofactor for many enzymes, including superoxide dismutase. Important for sperm production, immunity and wound healing. |
| Lycopene | 6000 mcg | Carotenoid antioxidant. |
| Astaxanthin | 4 mg | Carotenoid antioxidant that protects cell membranes from lipid peroxidation. |
| Vitamin A | 2000 IU | Vision, epithelial integrity and immunity. |
| Vitamin C | 30 mg | Water-soluble antioxidant. Regenerates vitamin E. |
| Vitamin E | 10 mg | Fat-soluble antioxidant that protects membranes from lipid peroxides. |
| Folic acid | 600 mcg | DNA synthesis and methylation. Helps prevent neural tube defects in pregnancy. |
| Omega-3 (EPA 90 mg, DHA 60 mg) | 150 mg total | Membrane fluidity and anti-inflammatory effects. DHA is a structural component of sperm membranes. |
| Piperine | 5 mg | Black pepper extract that improves absorption of other nutrients, especially CoQ10. |
What the textbooks say about the ingredients
- Katzung describes coenzyme Q10 as a potent antioxidant, with a possible role in muscle function and small blood pressure reductions in trials (Katzung's Basic and Clinical Pharmacology, 16th Edition, Coenzyme Q10 section).
- Campbell-Walsh Urology notes that antioxidant supplements in subfertile men may increase live birth rates, especially vitamin E, zinc and a multivitamin (Campbell Walsh Wein Urology, References section).
- Harper's Biochemistry explains the antioxidant network. Selenium works through glutathione peroxidase, and vitamin E reduces lipid peroxides (Harper's Illustrated Biochemistry, 32nd Ed, protection against radical damage).
Recent evidence
Recent systematic reviews of antioxidants in infertile men exist, including a 2026 meta-analysis on seminal outcomes (PMID 41983308) and a 2024 systematic review of oral antioxidants (PMID 38700012). I only saw the titles and metadata, not the results, so I can't say whether they show a benefit or how large it is.
How to take it
- The label says 1/2 or 1 tablet daily, or as directed by a physician or dietician.
- Store it below 30°C, away from direct sunlight and out of children's reach.
- The pack in your photos has an expiry of 06/2028.
Cautions
- Check with a doctor before use if you take warfarin or other anticoagulants. CoQ10, vitamin E and omega-3 can affect clotting or INR.
- Check with a doctor if you take blood pressure medicines (CoQ10 can lower BP), have a fish or seafood allergy, or have liver disease.
- If pregnancy is possible, check first. Vitamin A at 2000 IU is within the usual range, but total intake from other supplements should be reviewed.
- Piperine can change the blood levels of some drugs, such as phenytoin, propranolol and theophylline.
- Mild stomach upset or a fishy aftertaste are the usual side effects.
If you tell me why it was prescribed or recommended, I can say how well the evidence fits that use.
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