Is tacrolimus associated with lymphoma

Tacrolimus is a calcineurin inhibitor used as an immunosuppressant (post-transplant, topical for eczema). It suppresses T-cell activity, which can impair immune surveillance against malignant cells. The main concern is post-transplant lymphoproliferative disorder (PTLD), a spectrum ranging from benign lymphoid hyperplasia to aggressive lymphoma, most often EBV-driven B-cell lymphomas. Topical tacrolimus has also been scrutinized for a potential skin lymphoma risk, though evidence is less clear.

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tacrolimus lymphoma lymphoproliferative

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tacrolimus AND lymphoma AND "post-transplant lymphoproliferative"

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topical tacrolimus AND lymphoma risk

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Is tacrolimus associated with lymphoma

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