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embryonic folding

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embryonic folding lateral longitudinal folding embryo diagram labels

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This is an embryology model showing folding of the embryo during the 4th week. It demonstrates how the flat trilaminar embryonic disc becomes a curved, cylindrical embryo through:
  1. Cephalocaudal folding - head and tail folds form in the median plane.
  2. Lateral folding - the right and left sides move ventrally and fuse, closing most of the ventral body wall.
  3. Incorporation of yolk-sac endoderm - forms the primitive gut tube: foregut, midgut, and hindgut.
This conversion of a flat disc into a C-shaped embryo is described in The Developing Human: Clinically Oriented Embryology, p. 65.

Labels for the model

Label / structureWhat it represents
AmnionOuter membrane enclosing the embryo
Amniotic cavityFluid-filled space around the embryo
Embryo / embryonic bodyPink curved central developing body
Neural tube / developing brainDorsal blue structure, prominent in the head region
SomitesSmall paired bead-like segments along the back of the embryo
Intraembryonic coelomDeveloping body cavity, shown as spaces at the sides of the embryo
Extraembryonic coelom (chorionic cavity)Space outside the embryo but within the surrounding membranes
Yolk sac / umbilical vesicleYellow sac below or outside the embryonic body
Primitive gut tubeEndoderm-lined tube incorporated into the embryo during folding
ForegutCranial portion of the primitive gut, formed by head folding
MidgutPortion temporarily connected to the yolk sac
HindgutCaudal portion of the primitive gut, formed by tail folding
Connecting stalkAttachment between embryo and chorion; contributes to the umbilical cord
AllantoisSmall diverticulum extending into the connecting stalk
Primordial heart / pericardial regionVentral structure that moves beneath the head during head folding
Head foldCranial bend caused mainly by rapid growth of the developing brain
Tail foldCaudal bend that incorporates endoderm into the hindgut
Lateral body foldsRight and left folds that meet on the ventral surface

What each type of section shows

  • Side (sagittal) sections: show progression of head and tail folding and the embryo becoming C-shaped.
  • Cross (transverse) sections: show lateral folding, closure of the ventral body wall, and formation of the gut tube.
  • Later-stage sections: show a larger curved embryo with visible somites, primitive gut, yolk sac connection, and connecting stalk.
The main idea is: embryonic folding forms the body shape, primitive gut, ventral body wall, and early umbilical connection.

label with picture

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mkdir -p "/tmp/workspace/embryo-folding-label/output" && python - <<'PY' from PIL import Image, ImageDraw, ImageFont from pathlib import Path src=Path('/tmp/workspace/attachments/35da9749-81ad-4ea9-96b6-21ca20c54d27/1000214203.jpg') out=Path('/tmp/workspace/embryo-folding-label/output/embryo_folding_labelled.jpg') im=Image.open(src).convert('RGB') # Preserve original landscape model orientation. Extend left and bottom to prevent labels covering the model. W,H=im.size canvas=Image.new('RGB',(W+520,H+185),'white') canvas.paste(im,(0,0)) d=ImageDraw.Draw(canvas) try: font=ImageFont.truetype('/usr/share/fonts/truetype/dejavu/DejaVuSans-Bold.ttf',25) small=ImageFont.truetype('/usr/share/fonts/truetype/dejavu/DejaVuSans.ttf',20) title=ImageFont.truetype('/usr/share/fonts/truetype/dejavu/DejaVuSans-Bold.ttf',31) except: font=small=title=ImageFont.load_default() # title in extension d.text((20,H+18),'Folding of Embryo (4th week): labelled model',fill=(20,20,20),font=title) d.text((20,H+62),'A-B: sagittal sections (head and tail folding) C-E: transverse sections (lateral folding)',fill=(45,45,45),font=small) # Numbered annotation markers. Coordinates correspond to the original unrotated photo. # Labels selected for elements clearly distinguishable in this particular teaching model. items=[ ((1100,135),'1','Amnion / amniotic cavity'), ((1060,210),'2','Embryo (head fold)'), ((1030,285),'3','Somites'), ((905,220),'4','Yolk sac'), ((785,280),'5','Connecting stalk'), ((625,210),'6','Neural tube / developing brain'), ((570,345),'7','Primitive gut tube'), ((385,230),'8','Intraembryonic coelom'), ((335,395),'9','Lateral body folds'), ((110,255),'10','Foregut'), ((88,425),'11','Hindgut'), ] # marker circles, leader lines to a numbered legend at right legend_x=W+35 start_y=38 for i,(pt,num,label) in enumerate(items): x,y=pt # circle r=17 d.ellipse((x-r,y-r,x+r,y+r), fill=(255,245,45), outline=(10,10,10), width=3) # numerals centred bbox=d.textbbox((0,0),num,font=font) tw,th=bbox[2]-bbox[0],bbox[3]-bbox[1] d.text((x-tw/2,y-th/2-3),num,fill=(0,0,0),font=font) ly=start_y+i*54 # leader from circle to legend d.line((x+r,y,legend_x-12,ly+15),fill=(42,85,150),width=2) d.ellipse((legend_x-6,ly+9,legend_x+6,ly+21),fill=(42,85,150)) d.text((legend_x+12,ly),f'{num}. {label}',fill=(15,15,15),font=font) # outline panels A-E in subtle red and add stage terms for box,txt in [((930,75,1270,360),'A'),((930,365,1270,680),'B'),((500,70,900,355),'C'),((490,365,900,680),'D'),((80,80,475,680),'E')]: d.rectangle(box,outline=(190,30,55),width=3) # save high quality canvas.save(out,quality=94) print(out) PY

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Labelled embryonic folding model

embryo folding labelled

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The model shows folding of the embryo during the fourth week, including head-tail folding and lateral folding.
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