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Subconjunctival Hemorrhage
Subconjunctival hemorrhage - Wills Eye Manual
Subconjunctival hemorrhage (SCH) is bleeding between the conjunctiva and the underlying sclera. It appears as a sharply demarcated, bright red patch on the white of the eye where no individual vessels are visible through the blood.
Definition / Pathophysiology
Subconjunctival blood vessels rupture either spontaneously or after a sudden acute rise in venous pressure. The blood spreads smoothly beneath the conjunctiva, gently elevating it. No individual vessels are visible behind the hemorrhage (distinguishing it from conjunctival injection). - Rosen's Emergency Medicine, p. 879
Symptoms & Signs
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Usually asymptomatic - the patient often first notices it in the mirror
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Mild foreign body sensation possible, but no change in visual acuity
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Blood is visible under the conjunctiva, often sectoral but can be circumferential (360 degrees)
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Associated chemosis (conjunctival edema) may be present in larger hemorrhages
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Wills Eye Manual, p. 335
Etiology / Causes
| Category | Examples |
|---|
| Valsalva maneuver | Coughing, sneezing, vomiting, heavy lifting, straining with constipation |
| Traumatic | Blunt/penetrating injury; may mask retrobulbar hemorrhage or ruptured globe |
| Systemic disease | Hypertension, diabetes mellitus |
| Medications | Aspirin, clopidogrel, warfarin, ticagrelor, dabigatran, rivaroxaban, apixaban, edoxaban |
| Coagulopathy | Bleeding disorders, thrombocytopenia |
| Other | Topical steroid therapy, orbital mass (rare), idiopathic |
Warning Signs Requiring Urgent Evaluation
A 360-degree hemorrhage with any of the following mandates workup for globe perforation:
- Pain or chemosis
- Decreased visual acuity
- Photophobia
- High-impact mechanism of injury
Also check for retrobulbar hemorrhage if there is proptosis, restricted extraocular motility, or elevated IOP. - Rosen's Emergency Medicine, p. 879
Workup
- History - bleeding/clotting problems, medications (anticoagulants), eye rubbing, trauma, heavy lifting, Valsalva, recurrent SCH, cough history
- Check blood pressure - hypertension is a common underlying cause
- Ocular exam - slit lamp + fluorescein dye to check for corneal abrasion, globe perforation; check IOP and extraocular motility in traumatic cases
- Labs if recurrent: PT, aPTT, CBC with differential (rule out thrombocytopenia or leukemia), LFTs, Protein C and S
- CT/MRI orbits if proptosis or restricted motility is present (rule out orbital mass)
- Wills Eye Manual, pp. 335-336
Differential Diagnosis
- Kaposi sarcoma - red/purple elevated conjunctival lesion; check HIV status
- Conjunctival lymphoma or amyloid with secondary hemorrhage
- Episcleritis - sectoral redness with visible dilated vessels (vessels can be moved with a cotton-tip applicator, unlike SCH)
- Conjunctival laceration (more painful, requires evaluation for globe perforation)
- Scleritis (painful, deep injection)
Treatment
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No treatment required in the vast majority of cases
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Artificial tears (q.i.d.) for mild irritation
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Discourage elective use of aspirin/NSAIDs where possible
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Do NOT stop blood thinners without clearance from the patient's primary physician
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Manage underlying hypertension
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Wills Eye Manual, p. 336
Follow Up / Prognosis
- Resolves spontaneously within 2 to 4 weeks (Tintinalli: usually within 2 weeks)
- Reassurance is the mainstay of management for uncomplicated cases
- Return if blood does not fully resolve or recurrence occurs
- Refer to internist if hypertension or bleeding diathesis is identified
Key Takeaways
- Benign, self-limiting condition in most cases
- The alarming appearance often causes significant patient anxiety - reassurance is key
- Always rule out serious underlying trauma (ruptured globe, retrobulbar hemorrhage) in the correct context
- Recurrent episodes warrant coagulation studies and systemic workup
Sources: Wills Eye Manual 6e, p. 335-336 | Tintinalli's Emergency Medicine | Rosen's Emergency Medicine, p. 879