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Help me out how to assess and write the positive findings

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CT brain ischemic stroke findings reporting acute infarct

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MRI DWI FLAIR acute ischemic stroke positive findings

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Here is a structured assessment and reporting guide for this case based on the imaging films.

Patient Details

Basanagouda Patil | 59Y/M | Date: 03-Jul-2025 Studies: NCCT Brain + MRI Brain (Stroke Protocol: DWI, FLAIR, T2, GRE/FFE, MR Angiography)

Step-by-Step Assessment Approach

1. NCCT Brain — What to Look For

RegionKey Findings to Assess
ParenchymaHypodensity, loss of grey-white differentiation, cortical ribbon sign
Hyperdense vessel signLook for dense MCA/basilar (acute thrombus)
Cerebellum / BrainstemHypodensity, mass effect
VentriclesSize, shift, effacement
Basal gangliaLenticular nucleus obscuration
Skull/CalvariumFracture, bony lesions
From the NCCT images, the posterior fossa slices and supratentorial cuts need careful review. Small cortical or posterior fossa infarcts can be missed on CT.

2. MRI DWI — Critical Sequence

  • Positive finding: Focal bright (hyperintense) signal on DWI = restricted diffusion = acute infarct
  • Confirm with ADC map: corresponding dark (hypointense) signal confirms true restriction (not T2 shine-through)
  • From the DWI panel (left half of MRI film), there appear to be areas of hyperintensity in the posterior fossa / cerebellar region on lower cuts and supratentorial white matter on mid-level cuts — these are the key positive findings

3. FLAIR — DWI-FLAIR Mismatch Rule

DWI-FLAIR mismatch in acute stroke
  • If DWI bright but FLAIR normal → infarct is < 4.5 hours old (thrombolysis window)
  • If DWI bright AND FLAIR bright → infarct is > 4.5–6 hours (established)
  • The FLAIR sequence (right half of MRI film, T2W FLAIR AXIAL labeled) should be compared slice-by-slice with DWI

4. T2W / GRE (FFE) Sequences

  • T2W: Bright signal in infarct territory (may lag behind DWI in hyperacute phase)
  • *GRE/FFE (T2)**: Look for blooming artifact = hemorrhagic transformation or microbleeds (dark spots)
    • From the GRE panel (third film, right side labeled T2W FFE/GRE), check for any dark foci

5. MR Angiography — Vessel Assessment

From the MRA panel (third film, left side):
  • Normal: Both carotid systems and vertebrobasilar system show well-opacified vessels with smooth tapering
  • Positive findings to report:
    • Stenosis: Focal narrowing / signal dropout
    • Occlusion: Abrupt cutoff of vessel
    • Atherosclerotic irregularity: Irregular contour of vessel walls
    • Assess: ICAs, MCAs (M1/M2), ACAs, basilar artery, vertebral arteries, PCAs

How to Write the Positive Findings Report

Template

NCCT BRAIN:
- Hypo/isodense area noted in [location] suggestive of [acute/subacute] infarct
  / No significant hypodensity / No intracranial hemorrhage
- Hyperdense MCA sign: Present / Absent
- Midline shift: Present [X mm to left/right] / Absent
- Ventricles: Normal / Dilated / Effaced
- Posterior fossa: Normal / Hypodensity in [cerebellum/brainstem]

MRI BRAIN — STROKE PROTOCOL:

DWI/ADC:
- Focal area of restricted diffusion (DWI bright, ADC dark) noted in [location — e.g., 
  left MCA territory / right cerebellar hemisphere / right internal capsule]
  measuring approximately [X × Y cm], consistent with ACUTE INFARCT.

FLAIR:
- Corresponding FLAIR [hyperintensity / no signal change] at the above-described site,
  suggesting infarct age [>4.5 hrs if FLAIR positive / <4.5 hrs if FLAIR negative — 
  DWI-FLAIR mismatch].

T2W:
- [T2 hyperintensity / no signal change] in the infarcted territory.

GRE/T2*:
- No blooming artifact to suggest hemorrhagic transformation / microbleeds.
  [OR: Foci of blooming artifact noted in [location] — hemorrhagic transformation / 
  microbleeds cannot be excluded.]

MR ANGIOGRAPHY (Intracranial + Neck vessels):
- [Normal flow signal in bilateral ICAs, MCAs, ACAs, PCAs, vertebral arteries, 
  and basilar artery]
  [OR: Focal signal dropout / stenosis / occlusion noted at [location].]
- Carotid bifurcation: Normal / Atherosclerotic changes with [mild/moderate/severe] stenosis
- Vertebral arteries: Symmetrical / Dominant right/left / Hypoplastic [side]

IMPRESSION:
1. Acute ischemic infarct in [territory/location] — [size if measurable]
2. DWI-FLAIR mismatch [present/absent] — [thrombolysis window open/closed]
3. [MRA findings — occlusion/stenosis if present, or normal intracranial vasculature]
4. No intracranial hemorrhage / hemorrhagic transformation

Key Teaching Points for This Case

  1. Stroke protocol MRI is far superior to CT for acute infarct detection — especially posterior fossa (where CT has bone artifact)
  2. Always correlate DWI ↔ ADC ↔ FLAIR for confirmation and timing
  3. MRA without contrast (Time of Flight) is sufficient to assess large vessel occlusion (LVO) — the key treatable target
  4. Report territory (MCA/PCA/ACA/PICA/basilar), side, and approximate size
  5. GRE/FFE is the sequence to exclude hemorrhage before thrombolysis decisions
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