Fast management of bee bites

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Fast Management of Bee Stings

1. Stinger Removal

Remove the stinger immediately — the honeybee leaves a barbed stinger embedded in the skin that continues to pump venom. Scrape it off (e.g., with a card edge or fingernail) or use forceps. Speed matters more than technique. Wasps and hornets do not leave their stingers.

2. Local Reactions (Most Cases)

StepAction
Stinger outRemove promptly
ColdApply ice pack immediately to reduce pain and swelling
TopicalTopical anesthetics for pain relief
Oral antihistaminesFor pruritus and mild urticaria
NSAIDs/paracetamolFor pain
Persistent/large local swellingIntralesional triamcinolone (5 mg/mL diluted in 2% lidocaine) injected at the site
Severe local reactionOral prednisone
Most local reactions resolve within hours to a few days.

3. Systemic / Anaphylactic Reaction (Emergency)

Anaphylaxis can occur within minutes of the sting. Act immediately:
PriorityTreatment
First lineEpinephrine (adrenaline) 0.3 mL of 1:1000 IM (anterolateral thigh)
Repeat if neededRepeat epinephrine after 10 minutes if no improvement
AdjunctsIV/IM antihistamines (H1 + H2 blockers)
CorticosteroidsIV/IM corticosteroids to prevent biphasic reaction
BronchospasmInhaled bronchodilators (salbutamol)
Prolonged reactionCorticosteroids + epinephrine may be needed for several days
CarryAll susceptible persons should carry a self-injectable epinephrine device (EpiPen)

4. Delayed Reactions

  • Serum sickness (fever, urticaria, joint pain) may appear 7–10 days after the sting — treat with corticosteroids and antihistamines.
  • Granulomatous skin reactions at the sting site have been reported.

5. Long-Term Prevention (High-Risk Patients)

  • Refer to an allergist for evaluation.
  • Venom immunotherapy (VIT) — desensitization with purified bee/vespid venom significantly reduces risk of future anaphylaxis. Rush and ultra-rush protocols are available.
  • Sublingual immunotherapy looks promising as an alternative route.

Key Points

  • Epinephrine IM is the cornerstone of anaphylaxis — antihistamines and steroids are adjuncts only.
  • 10% of all anaphylaxis cases in the US are attributed to Hymenoptera stings.
  • At least 90–100 deaths per year in the US are due to insect sting anaphylaxis.
— Andrews' Diseases of the Skin, p. 514–515 | Rosen's Emergency Medicine, p. 817 | Tietz Textbook of Laboratory Medicine, 7th ed.
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