How many ml iodine contrast omnipaque 350 we can inject in young 23 y

How many ml iodine contrast (omnipaque 350) we can inject in young 23 y old patient

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Omnipaque 350 iohexol maximum dose mL/kg adult contrast injection limit

Here is a clear, procedure-by-procedure breakdown for Omnipaque 350 (iohexol 350 mg I/mL) in a healthy 23-year-old adult, based on the official FDA-approved prescribing information:

Omnipaque 350 - Maximum Doses by Procedure (Adult)

CT Scanning

Region	Recommended Volume
Head (rapid IV injection)	80 mL
Body (rapid IV injection)	60 - 100 mL

Excretory Urography (IV)

0.6 - 1.2 mL/kg body weight
For a 70 kg patient: ~42 - 84 mL (max ~102 mL)

Angiocardiography / Ventriculography

Single injection: 30 - 60 mL (usual: 40 mL)
Maximum cumulative total: 250 mL per study

Selective Coronary Arteriography

Per injection: 3 - 14 mL (usual: 5 mL per vessel)

Aortography / Visceral Arteriography

Aortic arch/ascending aorta: 20 - 75 mL per injection
Abdominal aorta and branches: 30 - 60 mL
Renal arteries: 5 - 15 mL
Maximum cumulative total: 250 mL

Digital Subtraction Angiography (IV-DSA)

Per injection: typically 40 - 60 mL
Maximum total: 250 mL

The Universal Maximum Rule

The maximum total volume of Omnipaque 350 for any single procedure or multiple combined procedures is 250 mL (= 87.5 g of iodine).

This applies to a normal-renal-function adult. For a 70 kg patient, 250 mL equals about 3.6 mL/kg, which stays well within the safe threshold.

Key Factors That Lower the Safe Limit

Even in a young healthy patient, always reduce or use caution if:

Renal impairment (CKD) - contrast-induced nephropathy risk
Dehydration - ensure adequate hydration before and after
Heart failure - osmotic load concern
History of contrast allergy - premedicate or avoid
Metformin use - hold 48 hours post-contrast if renal function is borderline
Thyroid disease - iodine load can trigger hyperthyroidism

Practical Summary for Your 23-Year-Old Patient

Scenario	Volume
Routine CT with contrast (body)	60 - 100 mL
CT head	80 mL
Angiography (total session)	up to 250 mL
Hard upper limit (any indication)	250 mL total

For routine CT in a healthy young adult with normal kidneys, 80-100 mL of Omnipaque 350 is the standard clinical dose. The absolute ceiling for any single imaging session is 250 mL.

Sources: FDA label for Omnipaque (iohexol) | GE Healthcare Omnipaque prescribing information

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