Medical pathology diagram: Amyloid molecular structure and fibril formation. Show beta-pleated sheet configuration of amyloid fibrils in cross-section. Include: 1) Normal protein folding vs misfolded protein, 2) Beta-pleated sheet arrangement with antiparallel strands shown in yellow/gold, 3) SAP (serum amyloid P) component attached in blue, 4) Glycosaminoglycan heparan sulfate in green, 5) Final amyloid fibril cross-section showing 7.5-10nm width. Label all components clearly. Medical textbook style with white background, clear labels in black text, colorful educational diagram for MBBS exam preparation.

Medical pathology diagram: Classification of Amyloidosis table and organ involvement. Show two main columns: 1) Systemic Amyloidosis (Primary AL type - plasma cell dyscrasia with immunoglobulin light chains shown in blue; Secondary AA type - chronic inflammation with SAA protein shown in orange; Familial/Hereditary with TTR protein shown in purple; Dialysis-related with Beta2-microglobulin shown in green) and 2) Localized Amyloidosis (Alzheimer disease brain, Type 2 diabetes pancreas, Medullary carcinoma thyroid). Each type shows the precursor protein and diseases. Bottom panel shows organs affected: heart, kidney, liver, spleen, tongue. Medical textbook style, white background, color-coded boxes, clear labels for MBBS pathology exam.

Medical pathology diagram: Staining properties of Amyloid - Congo red staining. Show two panels side by side: LEFT PANEL - Congo red stain under normal light microscopy showing amyloid deposits in salmon pink/red color in glomerulus and vessel walls, labeled "Salmon pink color under ordinary light". RIGHT PANEL - Same section under polarized light showing apple-green birefringence, labeled "Apple-green birefringence under polarized light". Additional small panels showing: Crystal violet metachromasia (purple to red color change), Thioflavin T fluorescence (yellow-green glow), PAS positivity (magenta). Include Congo red chemical structure note. Medical textbook style, high detail, labeled clearly for MBBS pathology exam.

Medical pathology diagram: Sago Spleen vs Lardaceous Spleen comparison. LEFT SIDE - Sago Spleen: cross-section of spleen showing discrete grey translucent nodules in white pulp (Malpighian corpuscles), resembling sago grains/tapioca, early amyloid deposit. Label: periarteriolar amyloid, 0.5-2mm nodules, grey translucent nodules. RIGHT SIDE - Lardaceous Spleen (Large waxy spleen): cross-section showing diffuse waxy pale deposits throughout red pulp, like bacon fat/lard appearance, advanced amyloid. Label: diffuse deposits in sinusoids and red pulp, pale waxy cut surface, enlarged spleen. Both sides show gross specimen and microscopic (Congo red stain) appearance. Color coding: normal spleen tissue in red-purple, amyloid deposits in pale yellow/white, Congo red positive in salmon pink. MBBS exam pathology diagram.