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Which one of these enzyme elevation suggests jaundice

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jaundice AND bilirubin

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Merck Manual jaundice bilirubin alkaline phosphatase cholestasis

The test that directly indicates jaundice is bilirubin, not an enzyme.
From this report:
  • Total bilirubin: 2.386 mg/dL - high (normal 0.3-1.2)
  • Direct bilirubin: 2.370 mg/dL - markedly high (normal 0.1-0.4)
Jaundice often becomes visible in the eyes/skin when total bilirubin reaches about 2.5-3 mg/dL, so this is very close to that range.
The relevant enzyme is:
  • Alkaline phosphatase (ALP): 386 U/L - high (normal 40-129), about 3 times the upper limit.
High direct bilirubin + ALP, with normal SGPT/ALT (19.5) and SGOT/AST (33), suggests a cholestatic/obstructive pattern, meaning impaired bile flow. Causes can include a bile-duct stone, narrowing/blockage of a bile duct, medication-related cholestasis, or other liver/biliary conditions. A high ALP supports this pattern but does not itself diagnose jaundice. Merck's jaundice guidance notes that bilirubin fractionation and ALP help distinguish cholestasis from liver-cell injury.
Also important:
  • Albumin 2.05 g/dL and total protein 5.48 g/dL are low. This needs medical review, especially at age 75.
Please contact the treating doctor promptly, ideally today or within 24-48 hours. They may consider repeat liver tests including GGT, an abdominal ultrasound, medication review, and tests of liver clotting function (PT/INR). Seek urgent care now for fever/chills, severe right-upper abdominal pain, vomiting, confusion/drowsiness, very dark urine with pale/clay stools, or worsening yellow eyes/skin.
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