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Airway Fire Protocol in Laser Surgery
Notes for MD Anaesthesiology Examination
1. Introduction
An airway fire is a rare but potentially fatal intraoperative emergency. The most common aetiology is laser use during airway surgery, though it can also occur during tracheostomy and tonsillectomy procedures. The combination of a high-oxygen environment, flammable endotracheal tubes (ETTs), and laser energy as an ignition source makes this a uniquely dangerous situation for the anaesthesiologist.
(Miller's Anesthesia 10e; Barash Clinical Anesthesia 9e)
2. The Fire Triad (Fire Tetrahedron)
A fire requires three elements simultaneously - remove any one to prevent or extinguish the fire:
| Element | Examples in Airway Surgery |
|---|
| Fuel | PVC/rubber ETT, dry gauze/sponges, drapes, charred tissue, airway mucosa |
| Oxidiser | Oxygen (>21%), Nitrous oxide (oxidiser, not fuel) |
| Ignition Source | Laser (CO2, Nd:YAG, KTP), electrosurgery unit (ESU/diathermy) |
Key fact: A PVC ETT will ignite in as little as 25% O2. Once ignited, it produces a "blowtorch" effect - an intensely burning jet of flame directed down the airway, producing toxic combustion debris.
(Barash 9e, p. 392)
3. Types of Lasers Used in Airway Surgery
| Laser | Wavelength | Properties | Eye Protection |
|---|
| CO2 | 10,600 nm | Interacts with water/any surface; primarily for airway procedures | Clear safety glasses sufficient |
| KTP (potassium titanyl phosphate) | 532 nm | Interacts with tissue pigment; delivered via flexible fibre | Tinted/wavelength-specific goggles |
| Nd:YAG | 1,064 nm | Deep tissue penetration; delivered via flexible fibre through bronchoscope | Tinted/wavelength-specific goggles |
CO2 laser: risk increases with continuous lasing >5 seconds (risk ×72) and lasing charred tissue (risk ×98). Every 10% increase in FiO2 above 60% raises fire risk ×2.3 with KTP laser.
(Barash 9e, p. 393-394)
4. Prevention of Airway Fire - The Anaesthesiologist's Role
4a. Pre-operative / Time-Out
- Discuss fire risk explicitly during surgical time-out with the entire team
- Assign roles: who stops laser, who removes ETT, who pours saline
- Post laser warning signs on OR doors
- Ensure wavelength-appropriate eye protection for all personnel (including patient)
- Have water/saline in a 60 mL syringe and basin immediately available at the field
4b. ETT Selection for Laser Surgery
No currently available ETT is completely laser-proof. Selection is based on laser type and wavelength.
| ETT Type | Advantages | Disadvantages |
|---|
| PVC | Inexpensive, nonreflective | Low melting point, highly combustible |
| Red rubber | Puncture-resistant, nonreflective | Highly combustible |
| Silicone rubber | Nonreflective | Combustible; burns to toxic ash |
| Metal (e.g., Laser-Flex, Norton) | Combustion-resistant, kink-resistant | Thick-walled flammable cuff, reflects laser, transfers heat |
| Commercially available laser-safe ETTs (e.g., Lasertubus, Sheridan) | Specifically designed - double-cuffed, indicator dye | Larger external diameter; not suitable for small infants |
Wrapping conventional ETTs with metallic foil tape is obsolete and not FDA-approved - the tape can break/unravel, the adhesive backing can ignite, and it may reflect laser onto non-targeted tissue.
(Morgan & Mikhail 7e, Tables 37-1 and 37-2)
4c. ETT Cuff Management
- Fill both cuffs with saline (not air) - water absorbs laser energy and resists ignition
- Add methylene blue dye to saline - acts as a visible indicator if the cuff is perforated by the laser (blue-stained fluid appears in the field)
- Double-cuffed laser tubes offer added protection: if proximal cuff is perforated, distal cuff continues to protect
- Position ETT cuff sufficiently deep below the vocal cords so it is away from the operative field
(Morgan & Mikhail 7e, p. 1474; ASA Practice Advisory)
4d. Gas Management
- Keep FiO2 as low as clinically feasible - target FiO2 <0.3 (30%) if tolerated
- Avoid nitrous oxide entirely - N2O is an oxidising agent that actively supports combustion
- Use air as the carrier gas - many patients tolerate FiO2 of 21%
- Confirm FiO2 <0.3 on end-tidal gas analyser before surgeon activates laser (may require several minutes to dilute O2 at current fresh gas flow)
- Use TIVA (Total IV Anaesthesia) with propofol infusion - avoids volatile agents and N2O
(Morgan & Mikhail 7e, p. 1474; ASA Practice Advisory)
4e. Laser Technique Precautions
- Surgeon should use pulsed lasing mode at minimum power
- Laser must be in STANDBY mode when not actively in use (not fired indiscriminately)
- Surgeon must give the anaesthesiologist adequate notice before activating laser (to confirm FiO2)
- Place saline-saturated pledgets/cottonoids around the ETT and adjacent tissue to limit ignition
- Avoid lasing adipose or charred tissue (highest fire risk)
- Limit continuous lasing duration to under 5 seconds per burst
5. Alternative Ventilation Strategies (Avoiding ETT Altogether)
Eliminating the ETT removes the primary fuel source:
| Technique | Details |
|---|
| Intermittent apnoea + mask ventilation | Patient apnoeic during lasing; re-oxygenated via mask between bursts. High FiO2 tolerated as no ETT in field |
| Intermittent apnoea + reintubation | ETT removed during lasing, replaced if SpO2 falls. Limited operative time per interval |
| Jet ventilation (Sanders injector) | Via rigid bronchoscope above or below vocal cords. Excellent surgical view. Risks: pneumothorax, mucosal drying, gas dissemination of papilloma fragments |
| High-frequency jet ventilation (HFJV) | Allows continuous gas exchange. Risk of barotrauma |
| Spontaneous ventilation | Deep anaesthesia (propofol + volatile/sevoflurane via side port). Risk: laryngospasm, hypoventilation |
(Cummings Otolaryngology; Barash 9e; Morgan & Mikhail 7e)
6. Recognition of Airway Fire - Early Warning Signs
Early recognition is life-saving. Signs include:
- Visible flame or flash in the operative field
- Unusual sound - a "pop" or "snap"
- Unusual odour or smoke
- Unexpected heat sensation felt by surgeon
- Unexpected movement or discolouration of breathing circuit or surgical drapes
- Unexpected patient movement
- Drop in SpO2 or sudden change in ventilator parameters
(WFSA Airway Fire Resource; ASA Practice Advisory)
7. Airway Fire Protocol - Immediate Management
This is the most exam-relevant section. Memorise the sequence:
ASA Algorithm / Standard Protocol (Morgan & Mikhail Table 37-3):
STEP 1 - STOP VENTILATION
- Cease all ventilation immediately
- Remove the ETT from the airway
STEP 2 - DISCONNECT AND STOP ALL GASES
- Turn off oxygen at the anaesthesia machine
- Disconnect the breathing circuit from the machine
- Stop N2O and all anaesthetic gas delivery
STEP 3 - REMOVE FLAMMABLE MATERIAL
- Remove the burning ETT from the airway
- Remove all flammable materials: sponges, pledgets, gauze
- Submerge the removed ETT in water/saline to extinguish it
STEP 4 - POUR SALINE INTO THE AIRWAY
- Pour saline or water directly into the trachea to extinguish residual fire
- This addresses any residual burning tissue/charring within the airway
STEP 5 - REASSESS AND REVENTILATE
- Reventilate with face mask once fire confirmed extinguished
- Avoid supplemental oxygen initially if clinically possible
- Reintubate when airway control is regained, before oedema develops
- Reintubation should ideally be coordinated with bronchoscopy
STEP 6 - ASSESS AIRWAY DAMAGE
- Perform bronchoscopy to:
- Confirm fire is extinguished
- Assess extent of thermal/inhalation injury
- Remove all foreign body fragments (ETT debris, ash, sponge pieces)
- Examine the entire airway including distal bronchi
- Serial chest X-rays
- Arterial blood gases (ABG) monitoring
- Consider bronchial lavage and corticosteroids for inhalation injury
(Morgan & Mikhail 7e; Miller's Anesthesia 10e; Barash 9e)
Quick Memory Aid: "STOP, DROP, POUR, SCOPE"
- STOP ventilation and laser
- DROP (remove) the ETT and all flammable materials
- POUR saline into the airway
- SCOPE (bronchoscopy) to assess damage
8. Post-Fire Management
- Transfer to ICU for monitoring
- Monitor for:
- Acute airway oedema (may require prolonged intubation or tracheostomy)
- Chemical/thermal tracheobronchitis
- ARDS from inhalation injury
- Pneumonia (secondary to retained debris)
- Late tracheal stenosis (can develop weeks to months later)
- IV corticosteroids (dexamethasone) to reduce airway inflammation
- Consider humidified oxygen and bronchodilators
- Nebulised N-acetylcysteine for mucosal protection
- Notify medicolegal and report the incident
9. Special Considerations
ETT Fire with Difficult Airway
A critical dilemma unique to anaesthesia: in patients with a known or anticipated difficult airway, removing a burning ETT may cause irreversible loss of airway access. The clinician must weigh the risk of fire-related injury versus the risk of complete airway loss. There is no universally agreed protocol - this must be anticipated pre-operatively and a rescue plan established.
(Miller's Anesthesia 10e, p. 922)
Paediatric Patients
- Smaller airways = smaller calibre ETTs with thinner walls = ignite faster
- Laser-compatible ETTs may not be available in very small sizes (Nd:YAG-compatible tubes not available in half sizes)
- HFJV or intermittent apnoea techniques often preferred in children
- Papillomatosis (recurrent respiratory papillomatosis, RRP) is the most common indication for laser airway surgery in children
Tracheostomy
- High-risk scenario for airway fire even without laser: the electrocautery/diathermy is used in proximity to the trachea while the patient is receiving supplemental O2 via ETT
- Should reduce FiO2 before tracheal incision
- Protocol remains the same
10. Summary Table - Prevention vs Management
| Prevention | Management |
|---|
| Fire risk discussion at time-out | Stop ventilation immediately |
| FiO2 <0.30; avoid N2O; use TIVA | Remove ETT from airway |
| Laser-safe ETT with saline-filled, methylene-blue cuff | Disconnect circuit, stop all gases |
| Surgeon confirms FiO2 before firing laser | Remove all flammable material |
| Laser in STANDBY when not in use | Pour saline into airway |
| Saline-soaked pledgets around ETT | Reventilate, reintubate |
| Pulsed mode, minimum power, avoid charred tissue | Bronchoscopy, CXR, ABG |
| Consider ETT-free technique (jet ventilation) | ICU monitoring, steroids |
Key Exam Points to Remember
- Fire triad: Fuel + Oxidiser + Ignition source. All three must be present.
- PVC ETT ignites at 25% O2 - it is never truly safe in laser surgery.
- No ETT is completely laser-proof - precautions reduce but never eliminate risk.
- Methylene blue in cuff saline = visual indicator of cuff puncture.
- N2O is an oxidiser - absolutely contraindicated in laser airway surgery.
- First step in airway fire = Stop ventilation AND remove ETT simultaneously.
- Pour saline into the airway - do not use CO2 fire extinguisher inside the airway.
- Bronchoscopy is mandatory after every airway fire to remove debris and assess injury.
- Continuous lasing >5 sec increases fire risk ×72 (Barash 9e).
- ASA Practice Advisory on Operating Room Fires is the authoritative guideline.
Sources: Miller's Anesthesia 10e (Ch. 66); Barash Clinical Anesthesia 9e (Ch. 5); Morgan & Mikhail's Clinical Anesthesiology 7e (Ch. 37); Cummings Otolaryngology Head & Neck Surgery; ASA Practice Advisory for Prevention and Management of Operating Room Fires; WFSA Airway Fire Resource