Hemodialysis prescription in pregnancy give me in a poster form

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hemodialysis prescription in pregnancy guidelines 2024 intensive dialysis

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Hemodialysis Prescription in Pregnancy Poster
Here is your evidence-based poster on hemodialysis prescription in pregnancy. Below is a summary of everything on the poster:

Hemodialysis Prescription in Pregnancy - Key Points

Dialysis Dose

  • Target: ≥ 36 hours/week for established HD patients (daily or nocturnal preferred)
  • Intensive HD (43 ± 6 hrs/wk) achieves live birth rate of 86% vs 61% with standard ~17 hrs/wk
  • Dose is titrated by residual kidney function - women starting dialysis during pregnancy may not need as intense a regimen if residual function is good
  • Target midweek pre-dialysis BUN < 35 mg/dL (urea < 12.5 mmol/L)

When to Initiate Dialysis in Pregnancy

  • Discuss at BUN > 42 mg/dL (urea > 15 mmol/L)
  • Initiate at BUN 48–56 mg/dL (urea 17–20 mmol/L)
  • Standard indications also apply: hyperkalemia, acidosis, uremic symptoms, fluid overload
  • At gestation ≥ 34 weeks, weigh risk of preterm delivery against dialysis initiation

Biochemical Targets

ParameterTarget
Hemoglobin10–11 g/dL (ESA + IV iron)
Bicarbonate18–22 mmol/L (adjust dialysate)
PhosphateNormal range (oral/dialysate supplement)
CalciumNormal range (vitamin D analogues)
Blood pressure< 140/90 mmHg (avoid ACEi/ARBs)

Fluid & Dry Weight

  • Increase dry weight target by ~0.5 kg/week during pregnancy
  • Avoid hypovolemia - it threatens uteroplacental perfusion

Anticoagulation

  • UFH requirement often increases due to pregnancy hypercoagulability - titrate accordingly

Nutrition

  • Increased protein and caloric needs - dietitian essential
  • Folic acid 5 mg/day, aspirin 75–150 mg/day pre-pregnancy and throughout

Fetal Monitoring

  • Weekly fetal surveillance after 24 weeks
  • Watch for IUGR, polyhydramnios, preterm labor
  • Multidisciplinary care with Maternal-Fetal Medicine

Post-Partum

  • Return to standard dialysis schedule
  • Reassess dry weight and antihypertensives weekly for 6–12 weeks

Sources: Comprehensive Clinical Nephrology 7e (Box 45.6), Brenner & Rector's The Kidney, KDIGO Women & Kidney Health Conference Report 2025, UK Renal Association Guidelines 2019

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Hemodialysis in Pregnancy - Poster 2
Here is a second version of the poster - this one uses a white background with a 6-box grid layout and covers a broader scope including:
  • Dialysis dose with outcome data
  • BUN/urea targets and initiation thresholds
  • Fluid & dry weight management
  • Biochemical targets (Hb, HCO₃, PO₄, Ca, K)
  • Safe vs. avoided medications (including MgSO₄ caution)
  • MDT monitoring + fetal surveillance
  • Pre-pregnancy counselling and post-partum care
Let me know if you'd like any changes - different color scheme, a specific section expanded, different layout, or a version focused on a particular trimester!
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