You are answering a USMLE-style medical question. Question: Five days after undergoing an emergency appendectomy under general inhalational anesthesia while on a trip to Haiti, a 43-year-old woman develops low-grade fever, vomiting, and abdominal pain. During the surgery, she received a transfusion of 1 unit of packed red blood cells. Three days after the surgery, she was stable enough to be transported back to the United States. She has no history of serious illness and takes no medications. Her temperature is 38.3°C (100.9°F), pulse is 80/min, and blood pressure is 138/76 mm Hg. Examination shows jaundice of the skin and conjunctivae. Abdominal examination shows moderate tenderness over the liver. The liver is palpated 2 to 3 cm below the right costal margin. Laboratory studies show: Hemoglobin count 12.0 g/dL Leukocyte count 10,400 mm3 Segmented neutrophils 55% Bands 1% Eosinophils 13% Lymphocytes 28% Monocytes 3% Platelet count 160,000 mm3 Serum Alkaline phosphatase 102 U/L Aspartate aminotransferase 760 U/L Bilirubin Total 3.8 mg/dL Direct 3.1 mg/dL Anti-HAV IgG positive Anti-HAV IgM negative Anti-HBs positive HBsAg negative Anti-HCV antibodies negative Abdominal ultrasonography shows an enlarged liver. A biopsy of the liver shows massive centrilobular necrosis. Which of the following is the most likely underlying cause of this patient's condition?" Options: A) Adverse effect of anesthetic B) Gram negative bacteria in the bloodstream C) Acalculous inflammation of the gallbladder D) Excessive lysis of red blood cells Reply with ONLY the letter of the correct answer (A, B, C, or D). No explanation.