I had an accident 2 months ago. The wound not healed. I want to test what are the test I would do please suggest
investigations tests for chronic non-healing wound 2 months traumatic ulcer workup
| Test | Why It's Done |
|---|---|
| Complete Blood Count (CBC) | Check for anemia, infection (raised WBC), low platelets |
| Random / Fasting Blood Sugar + HbA1c | Diabetes is the #1 cause of non-healing wounds |
| Serum Albumin & Pre-albumin | Assess nutritional status - low protein = poor healing |
| Kidney Function Tests (BUN, Creatinine) | Kidney disease impairs healing |
| Liver Function Tests | Liver disease affects clotting and protein synthesis |
| Coagulation Profile (PT, PTT, INR) | Check clotting ability |
| Thyroid Function (TSH, T3, T4) | Hypothyroidism slows wound healing |
| ESR / CRP | Markers of systemic inflammation or infection |
| Vitamin C, Zinc, Vitamin D levels | Deficiencies directly impair wound healing |
| HIV / Immunocompromised screen | Immune deficiency causes non-healing wounds |
| Test | Why It's Done |
|---|---|
| Wound swab culture & sensitivity | Identifies bacteria causing infection and the right antibiotic |
| Deep tissue culture | More accurate than surface swab for deeper infections |
| Wound biopsy | Critical after 3 months - rules out squamous cell carcinoma, melanoma, or other skin cancers that can mimic a non-healing wound. Also diagnoses rare conditions like pyoderma gangrenosum or vasculitis |
| Fungal culture (KOH prep) | Fungal infections (e.g., blastomycosis, sporotrichosis) cause chronic wounds |
| Test | Why It's Done |
|---|---|
| Ankle-Brachial Index (ABI) | Measures blood flow to the area - poor circulation = non-healing |
| Doppler Ultrasound | Checks arteries and veins supplying the wound area |
| Venous Duplex Scan | If the wound is on the leg, checks for venous insufficiency |
| Test | Why It's Done |
|---|---|
| X-ray of the area | Rules out underlying fracture, foreign bodies (glass, metal), or osteomyelitis (bone infection) |
| MRI or CT scan | If deep infection (osteomyelitis) or abscess is suspected |
| Bone Scan | If bone infection is strongly suspected |
| Test | Why It's Done |
|---|---|
| ANCA, ANA, RF (Autoimmune panel) | Autoimmune diseases like vasculitis can cause non-healing ulcers |
| Sickle Cell Screen (HPLC) | Sickle cell disease causes leg ulcers |
| Syphilis / VDRL | Syphilitic ulcers can appear chronic |
| TB skin test / Sputum culture | TB can cause skin ulcers |