Can you teach me all clinical examinations used in general medicine

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clinical examination techniques cardiovascular respiratory abdominal

Here is a complete structured guide to clinical examinations in general medicine, compiled from Harrison's Principles of Internal Medicine 22E, Goldman-Cecil Medicine, and Daroff's Neurology in Clinical Practice.

Clinical Examinations in General Medicine

The Universal Sequence (for any system)

Every clinical examination follows: Inspection → Palpation → Percussion → Auscultation (Exception: the abdomen - always auscultate before palpating/percussing to avoid altering bowel sounds.)

1. GENERAL / SYSTEMIC EXAMINATION

Before going system-by-system, every patient gets a general survey.

1a. Overall Inspection

  • Build: thin/obese, nutritional status, hydration
  • Conscious level: alert, drowsy, confused (GCS if needed)
  • Appearance: distressed, comfortable, jaundiced, pale, cyanosed
  • Posture and gait (briefly, walking into the room)
  • Speech: dysarthria, aphasia, hoarseness

1b. Vital Signs

ParameterTechniqueKey Notes
TemperatureOral/axillary/tympanic>38°C = fever; <36°C = hypothermia
PulseRadial - rate, rhythm, volume, characterNormal 60-100 bpm; regular/irregular
Blood PressureSeated, arm at heart level, 5-10 min rest, correct cuff sizeBoth arms (>10 mmHg diff is abnormal). Korotkoff I = systolic, V = diastolic
Respiratory RateCount breaths for 60 secondsNormal 12-20/min; most underrecorded vital sign
SpO2Pulse oximetryNormal ≥95%; finger vs toe gap >2% = peripheral arterial disease
BMI / WeightScale + heightDocument at every admission
Blood pressure pearls (Harrison's):
  • Systolic leg pressure is normally up to 20 mmHg higher than arm - reversed = coarctation or aortic dissection
  • "White coat hypertension": BP >130/80 in clinic but <130/80 out of clinic, no end-organ damage
  • Ankle-Brachial Index (ABI): ankle systolic ÷ higher brachial pressure. Low ABI = peripheral arterial disease; powerful predictor of cardiovascular mortality

1c. Hands

  • Clubbing: loss of nail-fold angle; 5 causes per system (lung cancer, fibrosis, bronchiectasis, cyanotic heart disease, liver cirrhosis, IBD)
  • Peripheral cyanosis: blue/cold fingers (low flow)
  • Koilonychia: spoon-shaped nails - iron deficiency anaemia
  • Leukonychia: white nails - hypoalbuminaemia
  • Pallor: palmar crease pallor = Hb <9 g/dL roughly
  • Asterixis (flap): outstretched hands, wrists extended - hepatic, uraemic, or CO2 retention encephalopathy
  • Dupuytren's contracture: palmar fibrosis - liver disease, diabetes, familial
  • Splinter haemorrhages: infective endocarditis, vasculitis
  • Osler's nodes / Janeway lesions: endocarditis
  • Tremor (resting, postural, intention): see Neurology section

1d. Face

  • Eyes: jaundice (sclerae), anaemia (conjunctivae), Horner's (ptosis + miosis + anhidrosis), exophthalmos (thyroid), xanthelasma, arcus cornealis
  • Mouth: angular stomatitis (B12/iron def), central cyanosis (tongue and lips), leukoplakia, oral candidiasis, gum hypertrophy (phenytoin, CCBs, leukaemia)
  • Parotid enlargement: alcoholic liver disease
  • Malar flush: mitral stenosis
  • Facies: myxoedema, Cushingoid, acromegaly, Parkinsonism (hypomimia), progressive supranuclear palsy (worried expression)

1e. Neck

  • JVP: see CVS section (very important bedside venous pressure measure)
  • Lymph nodes: anterior/posterior cervical, supraclavicular (Virchow's node = gastric/lung cancer), axillary, inguinal
  • Thyroid: palpate from behind, swallows on swallowing; auscultate for bruit
  • Carotid bruit: auscultate at angle of mandible

1f. Oedema

  • Peripheral: pitting oedema at ankles/sacrum - cardiac, hepatic, nephrotic, nutritional
  • Non-pitting: lymphoedema, myxoedema
  • Press firmly for 10-15 seconds - depth of pit correlates roughly with severity

2. CARDIOVASCULAR SYSTEM (CVS) EXAMINATION

(Based on Harrison's Principles of Internal Medicine 22E, Chapter 246)

Sequence: Position patient at 45°, adequately exposed from waist up.

2a. Jugular Venous Pressure (JVP)

The JVP is the single most important bedside measurement of volume status.
  • Use the internal jugular vein (preferred - direct line to RA; external JV is valved)
  • Measure the vertical height of venous pulsation above the sternal angle (angle of Louis) at 45°
  • Normal: <4.5 cm above sternal angle at 45°
  • Tip: pulsations above the clavicle in the sitting position are always abnormal (RA is ≥10 cm below clavicle)
Distinguishing JVP from carotid pulse:
FeatureJVPCarotid
Obliterable by pressureYesNo
WaveformBiphasic (a and v waves)Monophasic
Changes with postureYesNo
Changes with inspirationYesNo
JVP waveform components:
  • a wave - RA presystolic contraction (after P wave on ECG); absent in AF; cannon a wave = AV dissociation (VT!)
  • x descent - RA pressure fall after tricuspid opening
  • c wave - tricuspid bulging into RA during early systole
  • v wave - atrial filling during ventricular systole; giant v wave = tricuspid regurgitation
  • y descent - tricuspid opens, RA empties
  • Prominent y descent + pericardial knock = constrictive pericarditis
Clinical meanings:
  • Elevated JVP: fluid overload, right heart failure, tamponade, SVC obstruction
  • Elevated JVP with elevated JVP rising on inspiration (Kussmaul's sign): constrictive pericarditis, restrictive cardiomyopathy
  • Elevated JVP (>10 mmHg) predicts pulmonary wedge pressure >22 mmHg (PPV 88%)

2b. Arterial Pulse

  • Best assessed at the carotid for character; radial for rate and rhythm
  • Rate, rhythm, volume, character, radio-radial/radio-femoral delay, vessel wall
Pulse character:
Pulse TypeCharacterCause
Pulsus parvus et tardusWeak, slow upstrokeSevere aortic stenosis
Corrigan's/water-hammerSharp rise, rapid collapseSevere aortic regurgitation
BisferiensTwo systolic peaksHOCM, AR
Pulsus paradoxus>10 mmHg fall in systolic on inspirationCardiac tamponade, massive PE, severe obstructive lung disease, tension pneumothorax
Pulsus alternansBeat-to-beat amplitude variation (regular rhythm)Severe LV systolic dysfunction
AnacroticSlow notched upstrokeSevere AS
Pulsus paradoxus measurement: inflate BP cuff above systolic; slowly deflate; note the pressure at which Korotkoff sounds are heard only in expiration, then the pressure at which heard in every beat. Difference >10 mmHg = positive.

2c. Blood Pressure

  • Both arms; >10 mmHg difference = subclavian/atherosclerotic disease, coarctation, dissection
  • Systolic legs > arms normally; reversed = coarctation
  • Measure ABI in peripheral arterial disease

2d. Precordial Examination

Inspection:
  • Visible apex beat: midclavicular line, 5th ICS in thin adults
  • Visible pulsations elsewhere = abnormal
  • Right parasternal pulsation = ascending aortic aneurysm
Palpation:
  • Patient supine 30°, enhanced in left lateral decubitus
  • Apex beat: location (normally ≤5th ICS, midclavicular line), size (<2 cm), character
    • Heaving/sustained = LV hypertrophy (pressure overload: AS, hypertension)
    • Hyperdynamic/thrusting = LV volume overload (MR, AR)
    • Displaced/diffuse = dilated cardiomyopathy
  • Parasternal heave: RV enlargement (pressure or volume overload)
  • Thrills (palpable murmurs): grade 4+ murmurs; location identifies origin
  • Loud P2 palpable at left upper sternal border = pulmonary hypertension

2e. Cardiac Auscultation

Areas:
  • Aortic: 2nd right ICS
  • Pulmonary: 2nd left ICS
  • Tricuspid: left lower sternal border (4th/5th ICS)
  • Mitral: apex (5th ICS, midclavicular line) - listen with bell for low-pitched sounds
First Heart Sound (S1):
  • Mitral + tricuspid closure
  • Loud S1: early rheumatic mitral stenosis, short PR interval, hyperkinetic states
  • Soft S1: late rheumatic MS (calcified leaflets), long PR interval, LV systolic dysfunction, beta-blockers
  • Splitting: heard in young patients and RBBB (delayed tricuspid closure)
Second Heart Sound (S2):
  • Aortic (A2) + pulmonary (P2) closure
  • Physiologic splitting: widens on inspiration (more right-sided filling), narrows on expiration
  • Wide splitting: RBBB, severe MR (early aortic closure)
  • Fixed splitting: ASD (no respiratory variation) - classic sign
  • Reversed/paradoxical splitting: components audible at end-expiration, narrow on inspiration - LBBB, RV pacing, severe AS, HOCM, acute MI
  • Loud P2: pulmonary hypertension (may be palpable)
  • Narrow single S2: pulmonary hypertension
S3 (Third Heart Sound):
  • Low-pitched, early diastolic; heard at apex with bell
  • In adults: always pathological - LV failure, dilated cardiomyopathy
  • In children/young adults: can be normal ("physiologic S3")
  • Sounds like "Ken-TUCK-y"
S4 (Fourth Heart Sound):
  • Low-pitched, late diastolic (pre-systolic); heard at apex
  • Reflects stiff ventricle (LVH, ischaemia, hypertrophic cardiomyopathy)
  • Sounds like "TEN-nes-see"
  • Never normal in adults
Heart Murmur Grading:
GradeDescription
1Barely audible (only heard in ideal conditions)
2Faint but clearly audible
3Moderate, no thrill
4Loud + palpable thrill
5Very loud, heard with stethoscope partially off chest
6Heard without stethoscope
Systolic Murmurs:
MurmurTimingBest HeardRadiationQuality
MR (chronic)HolosystolicApexAxillaBlowing
ASMidsystolic (ejection)Aortic areaCarotidsHarsh, crescendo-decrescendo
TRHolosystolicLeft lower sternal borderIncreases with inspiration (Carvallo's sign)Blowing
VSDHolosystolicLeft sternal borderRadiates all overHarsh
HOCMMidsystolicLeft lower sternal borderIncreases with Valsalva/standing, decreases with squattingHarsh
Pulmonary stenosisMidsystolicPulmonary areaEjection clickHarsh
Severe AS signs: parvus et tardus carotid pulse, late-peaking grade ≥3 murmur, soft or absent A2, S4 at apex, sustained LV impulse
Diastolic Murmurs (always pathological):
MurmurTimingBest HeardRadiation
AREarly diastolic decrescendoLeft sternal border (lean forward, expiration)-
MSMid-diastolic, low-pitched rumbleApex (bell, left lateral decubitus, expiration)-
Manoeuvres:
  • Valsalva: decreases preload - most murmurs softer; HOCM and MVP murmur louder
  • Squatting: increases preload and afterload - HOCM murmur softer
  • Standing: decreases preload - HOCM murmur louder
  • Handgrip: increases afterload - MR/AR louder, AS softer
Heart sound diagrams showing S1, S2 splitting patterns and murmur configurations
Heart sound splitting patterns - Harrison's 22E
Pulse character waveforms showing normal, AS, AR, HOCM, dicrotic patterns
Carotid pulse character waveforms - Harrison's 22E

2f. Peripheral Vascular Examination

  • Palpate all peripheral pulses: radial, brachial, carotid, femoral, popliteal, dorsalis pedis, posterior tibial
  • Auscultate for bruits: carotid, subclavian, renal (epigastric), femoral
  • Bruit extending into diastole or with thrill = severe obstruction
  • Check for lower limb oedema, skin changes (lipodermatosclerosis, venous ulcers), temperature asymmetry

3. RESPIRATORY SYSTEM EXAMINATION

(Harrison's Principles of Internal Medicine 22E, Chapter 262)

Position: Patient sitting, examine posterior chest first, then anterior.

3a. Inspection

  • Rate and pattern: tachypnoea (>20/min), bradypnoea, Cheyne-Stokes (central apnoeic cycles - heart failure, CNS disease), Kussmaul (deep, sighing - metabolic acidosis), Biot's (irregular - brainstem damage)
  • Accessory muscle use: sternocleidomastoid, scalenes - respiratory distress
  • Intercostal recession: severe obstruction in children
  • Barrel chest: AP diameter equal to transverse; COPD/emphysema
  • Kyphoscoliosis: can cause restrictive defect
  • Asymmetric expansion: collapse, pneumothorax, effusion on affected side
  • Tracheal position: midline? Deviation away from effusion/tension pneumothorax; towards collapse

3b. Palpation

  • Tracheal position (finger in sternal notch)
  • Chest expansion: thumbs meet at midline over lower posterior chest; should expand symmetrically ≥5 cm
  • Tactile (vocal) fremitus: place ulnar aspect of hand or palm on chest; say "99"
    • Increased = consolidation (fluid-filled alveoli transmit better)
    • Decreased/absent = effusion, pneumothorax, thick chest wall

3c. Percussion

  • Middle finger of non-dominant hand as pleximeter; tap with middle finger of dominant hand
  • Percuss comparing side to side symmetrically
  • Normal: resonant
  • Dull: consolidation, collapse, pleural effusion, mass
  • Stony dull: pleural effusion (classically)
  • Hyper-resonant: pneumothorax, emphysema
  • Diaphragm excursion: mark dullness at end-expiration and end-inspiration (normal excursion ~5 cm)

3d. Auscultation

  • Use diaphragm; compare sides methodically
  • Breath sound character:
SoundNormal?Cause when abnormal
VesicularNormal peripheral lung-
BronchialNormal only over tracheaConsolidation (pneumonia) when heard peripherally
BronchovesicularNormal over main bronchiMild consolidation when elsewhere
Diminished/absentAbnormalEmphysema (diffuse), pneumothorax, effusion (unilateral)
  • Added sounds:
SoundDescriptionCause
Crackles (rales)Discontinuous, popping soundsFine: pulmonary oedema (bases), IPF (Velcro-like, bilateral bases); Coarse: pneumonia, bronchiectasis
WheezesContinuous, musical, usually expiratoryAsthma (polyphonic), COPD, tumour (monophonic, fixed)
RhonchiLow-pitched continuous, like snoringSecretions in medium airways; bronchitis, COPD
StridorHigh-pitched inspiratory wheeze over neckUpper airway obstruction (epiglottitis, foreign body, tumour)
Pleural rubCreaking, leathery; both phasesPleuritis (pneumonia, PE, malignancy)
Vocal resonance tests:
  • Whispered pectoriloquy: ask patient to whisper "1-2-3"; if clearly heard = consolidation
  • Bronchophony: say "99"; louder than normal = consolidation
  • Egophony: say "EEE"; if you hear "AHH" = consolidation (pneumonia); not heard in fibrosis
Summary of clinical signs by diagnosis:
ConditionExpansionPercussionBreath soundsVocal fremitusAdded
ConsolidationReduced (affected)DullBronchialIncreasedCrackles, egophony
EffusionReduced (affected)Stony dullAbsent/reducedAbsentPleural rub (edge)
PneumothoraxReduced (affected)Hyper-resonantAbsentAbsent-
CollapseReduced (affected)DullReduced/absentReduced-
EmphysemaReduced (both, barrel)Hyper-resonantReduced (both)ReducedProlonged expiration
FibrosisReduced (both)NormalVesicular reducedNormalFine basal crackles (Velcro)
Asthma (acute)Reduced (both)Normal/hyperReducedNormalPolyphonic wheeze

4. ABDOMINAL EXAMINATION

(Goldman-Cecil Medicine, International Edition)

Position: Patient supine, one pillow, adequately exposed from xiphisternum to pubic symphysis. Ask them to keep arms at sides and legs flat.

4a. Inspection

Survey for:
  • Scars: location suggests prior surgery (RIF appendicectomy, midline laparotomy, RUQ cholecystectomy)
  • Distension: generalised (the 5 Fs: Fat, Fluid/ascites, Faeces, Flatus, Fetus/mass) vs localised
  • Prominent veins: periumbilical - portal hypertension (caput medusae); inferior epigastric collaterals - IVC obstruction
  • Visible peristalsis: small bowel obstruction, pyloric stenosis (epigastric, left to right)
  • Hernias: umbilical, epigastric, inguinal (ask patient to cough/stand)
  • Skin: striae (purple = Cushing's; white = pregnancy/obesity), spider naevi (>5 = liver disease), jaundice, Grey-Turner's/Cullen's sign (bruising in flanks/periumbilical = retroperitoneal haemorrhage, severe pancreatitis)
  • Asymmetry: organomegaly, mass

4b. Auscultation (before palpation/percussion in the abdomen)

  • Bowel sounds: listen in one spot (e.g., right iliac fossa) for 15-30 seconds
    • Normal: intermittent gurgles
    • Increased/hyperactive: early obstruction, gastroenteritis, after eating
    • Absent (>3 min silence): paralytic ileus, peritonitis, late obstruction
    • Tinkling/high-pitched: mechanical obstruction
  • Bruits: renal arteries (lateral to umbilicus - renovascular hypertension); aortic (epigastric - aneurysm/stenosis); hepatic bruit (hepatocellular carcinoma)
  • Note: routine auscultation for bowel sounds has limited value in patients without abdominal pain

4c. Percussion

  • Cursory light percussion across all 9 regions first - dullness, tympany, unexpected tenderness
  • Liver size: upper border of dullness in midclavicular line (MCL) on full expiration, lower border dullness in MCL on full inspiration; normal span 6-12 cm
  • Splenomegaly: percussion in left upper quadrant near 10th rib posterior to midaxillary line - dullness distinct from gastric tympany suggests spleen
  • Ascites: percuss for flank dullness (flanks dull, central tympany); if dull, test for shifting dullness: percuss flank to mark dullness, keep finger there, roll patient away - if line of dullness shifts upward = positive (most sensitive bedside sign for ascites)
  • Fluid thrill (for massive ascites): flick one flank while pressing midline with other hand's edge, second hand on opposite flank detects impulse

4d. Palpation

Always start away from the site of pain. Begin with light palpation, then deep.
Light palpation:
  • Watch the patient's face, not the abdomen
  • Detect guarding (voluntary or involuntary muscle spasm), tenderness, superficial masses
  • Involuntary guarding + rigidity = peritonism
Deep palpation - organ assessment:
Liver: start in RIF, hand flat, ask patient to breathe in and out; edge moves down on inspiration; palpate upward on each inspiration, feel for the edge. Assess: size (cm below costal margin), consistency (hard = malignancy, fibrosis; soft = congestive), tenderness, surface (smooth vs nodular), pulsatility (TR)
Spleen: start in RIF, move toward LUQ; use bimanual technique (left hand posteriorly supporting left costal margin, right hand palpating below); asks patient to breathe in. Cannot get above it (contrast with enlarged left kidney). Tip of enlarged spleen = splenomegaly:
  • Grade I: just palpable
  • Grade II: to umbilicus
  • Grade III: into RIF (massive)
Kidneys: bimanual palpation (ballot technique); right kidney easier to feel than left; kidneys ballottable (unlike spleen). Polycystic kidneys can be massive bilateral.
Aorta: palpate in epigastrium, expansile pulsation (width >3 cm = aneurysm). In thin patients normal aorta felt easily.
Bladder: dull to percussion, arises from pelvis, cannot get below it.
Renal angle tenderness: fist percussion over costovertebral angle (CVA) - positive in pyelonephritis, renal stones.
Special signs:
  • Murphy's sign: 2 fingers in RUQ, patient takes deep breath; arrest of inspiration due to pain = positive = acute cholecystitis (false positive: hepatitis)
  • McBurney's sign: tenderness at McBurney's point (1/3 from ASIS to umbilicus) = appendicitis
  • Rebound tenderness (Blumberg's): press slowly, release rapidly - pain worse on release = peritoneal irritation
  • Rovsing's sign: pressure in LIF causes pain in RIF = appendicitis
  • Obturator test: flex and internally rotate right hip - pain in RIF = inflamed appendix/pelvic abscess
  • Psoas sign: extend right hip (patient left lateral) - pain in RIF = retrocaecal appendicitis
  • Carnett's test: patient tenses abdominal wall (head lift) - if tenderness worse = abdominal wall source; if less = intra-abdominal source

4e. Rectal Examination

Indicated in: rectal/perianal symptoms, suspected GI bleeding, incontinence, acute abdomen.
  • Inspect perianal area: fissures, fistulas, haemorrhoids, skin tags
  • Digital: assess anal tone, rectal wall circumferentially for masses, prostate in males (size, consistency, tenderness), cervix in females

5. NEUROLOGICAL EXAMINATION

(Bradley and Daroff's Neurology in Clinical Practice)

5a. Philosophy: Start During the Interview

  • Hypomimia (expressionless face) = Parkinsonism or depression
  • Worried/astonished expression = progressive supranuclear palsy
  • Ptosis = myasthenia gravis or brainstem lesion
  • Speech = dysarthria, aphasia, spasmodic dysphonia
  • Involuntary movements during history-taking

5b. Mental Status

  • Orientation: time, place, person
  • Attention: months backwards, serial 7s
  • Memory: 3-word recall (immediate and 5-minute)
  • Language: naming, repetition, comprehension, reading, writing
  • Calculation, visuospatial function, executive function (frontal lobe)
  • Validated tools: MMSE (30 points), MoCA (for mild cognitive impairment, 30 points)

5c. Cranial Nerves (CNs)

CNTestKey Findings
I - OlfactoryTest each nostril (coffee, vanilla - not pungent)Anosmia: head injury, Parkinson's, olfactory groove meningioma
II - OpticVisual acuity (Snellen), visual fields (confrontation), pupil reactions (RAPD = swinging flashlight test), fundoscopyPapilloedema = raised ICP; optic atrophy; RAPD = optic nerve lesion
III, IV, VIEye movements (horizontal and vertical), nystagmus, pupil shape/size/reactivity, ptosisCN III palsy: ptosis, "down and out", dilated pupil; CN VI: failure to abduct
V - TrigeminalFacial sensation (all 3 divisions), corneal reflex, jaw opening/deviation, masseter/temporalis powerCorneal reflex absent = V or early VII lesion
VII - FacialRaise eyebrows, close eyes tight, show teeth, puff cheeksUMN VII (stroke): forehead spared (bilateral cortical supply); LMN VII (Bell's): forehead involved, complete weakness
VIII - VestibulocochlearWhisper test, tuning fork (Rinne and Weber)Rinne positive = normal or SNHL; Weber lateralises to better ear in SNHL, worse ear in conductive
IX, XPalatal movement (say "ahhh"), gag reflex, voice qualityUnilateral palate deviation away from lesion
XI - AccessoryTrapezius (shrug against resistance), sternocleidomastoid (turn head against resistance)Lesion: ipsilateral trapezius + contralateral SCM weakness
XII - HypoglossalProtrude tongueDeviation toward side of LMN lesion

5d. Motor System

Inspection:
  • Wasting, fasciculations (LMN)
  • Involuntary movements: tremor, chorea, dystonia, myoclonus, hemiballismus
Tone:
  • Spasticity (velocity-dependent resistance, clasp-knife): UMN - stroke, MS, cord lesion
  • Rigidity (equal resistance throughout range): extrapyramidal - Parkinson's (lead-pipe or cog-wheel with tremor)
  • Hypotonia/flaccidity: LMN, cerebellar, acute UMN shock
  • Test: flex/extend limbs passively at each joint
Power (MRC Grading):
GradeDescription
0No movement
1Flicker of movement
2Movement with gravity eliminated
3Movement against gravity only
4Movement against some resistance (4-, 4, 4+)
5Normal full power
Upper vs Lower Motor Neuron:
FeatureUMNLMN
ToneIncreased (spastic)Decreased (flaccid)
PowerWeakness (pyramidal distribution)Weakness (focal/radicular)
ReflexesHyperreflexiaHyporeflexia/absent
PlantarsExtensor (Babinski)Flexor
FasciculationsAbsentPresent
WastingLate/mildEarly/prominent
Practical tests (save time):
  • Pushup from floor, rising from chair without arms = proximal power
  • Walk on toes (S1/gastrocnemius), walk on heels (L4-5/tibialis anterior)
  • Pronator drift: arms outstretched, palms up, eyes closed; weak arm drifts down and pronates

5e. Reflexes

ReflexTestRoot Level
Biceps jerkTap biceps tendonC5-C6
Supinator/brachioradialis jerkTap distal radiusC5-C6
Triceps jerkTap triceps tendonC7-C8
Finger jerkTap flexed fingersC8
Knee jerk (patellar)Tap patellar tendonL3-L4
Ankle jerk (Achilles)Tap Achilles tendonS1-S2
Plantar responseStroke lateral sole with keyL5-S1
  • Grading: 0 (absent), 1+ (reduced), 2+ (normal), 3+ (brisk), 4+ (clonus)
  • Clonus: >5 beats = UMN lesion
  • Hoffman's reflex: flick distal middle finger = thumb flexion; UMN sign in upper limb
  • Plantar (Babinski): extensor (big toe extends, toes fan) = UMN lesion
Superficial reflexes (absent in UMN lesion):
  • Abdominal reflexes: stroke toward umbilicus in each quadrant (T8-T12)
  • Cremasteric reflex: stroke inner thigh = testis rises (L1-L2)

5f. Coordination

Cerebellar signs (mnemonic: DANISH):
  • Dysdiadochokinesis - rapidly alternating movements (forearm pronation/supination)
  • Ataxia - gait (broad-based, staggering), Romberg's negative (cerebellar)
  • Nystagmus - fast phase to side of lesion (horizontal)
  • Intention tremor - finger-nose test (tremor increases approaching target), heel-shin test
  • Scanning speech - dysarthric, monotone, staccato
  • Hypotonia - reduced tone
Romberg's test: stand feet together, arms outstretched, eyes open then closed. Falls with eyes closed but not open = proprioceptive ataxia (posterior column/dorsal root lesion). Cerebellar ataxia = falls with eyes open AND closed.

5g. Sensory Examination

Test in a dermatomal pattern; compare left vs right; distal vs proximal.
Primary modalities:
  • Pain/temperature (spinothalamic tract): pinprick; temperature
  • Light touch: cotton wool
  • Vibration sense (posterior column): 128 Hz tuning fork on bony prominences (great toe, malleolus, knee, anterior iliac spine, sternum - go distal to proximal)
  • Proprioception (joint position sense, JPS) (posterior column): grip the toe/finger at the sides, move up or down; patient identifies direction with eyes closed
Higher cortical sensory tests (parietal lobe):
  • Graphesthesia: write number on palm
  • Stereognosis: identify object in hand
  • Sensory extinction: stimulate both sides simultaneously; parietal lesion extinguishes contralateral stimulus

5h. Gait Assessment

Examine every neurological patient walking:
Gait TypeDescriptionCause
Spastic (hemiplegic)Circumduction of extended leg, arm flexedStroke, UMN lesion
Scissor gaitBoth legs spastic, adducted, cross overBilateral UMN (cerebral palsy, bilateral stroke)
ParkinsonianStooped, shuffling, small steps, reduced arm swing, festination, en bloc turnsParkinson's disease
Cerebellar (ataxic)Wide-based, staggering, titubationCerebellar lesion (alcohol, MS, tumor)
High-stepping (foot drop)Exaggerated hip and knee flexion, steppageL4-5 lesion, peroneal nerve palsy
WaddlingSide-to-side swayingProximal myopathy, hip disease
Sensory ataxiaWide-based, stamps feet, worse in dark, Romberg positivePosterior column lesion (B12 def, tabes dorsalis)
ApraxicFeet appear glued to floor, shuffling, normal in bedNormal-pressure hydrocephalus, frontal lesion

6. THYROID EXAMINATION

  • Inspection: neck swelling? Moves on swallowing (thyroid tissue) vs protrusion of tongue (thyroglossal cyst)
  • Palpation: stand behind patient; use 2-3 fingers bilaterally to palpate lobes and isthmus; ask patient to swallow sip of water; feel for size, consistency, tenderness, nodules, tracheal deviation
  • Percussion: retrosternal extension? Percuss over sternum
  • Auscultation: thyroid bruit = hyperthyroidism (increased vascularity)
  • Signs of hyper/hypothyroidism: pulse rate, AF, tremor, eye signs (exophthalmos, lid lag, lid retraction, ophthalmoplegia in Graves'), proximal myopathy, pretibial myxoedema, onycholysis, reflexes (brisk in hyper, delayed relaxation in hypo)
  • Pemberton's sign: raise both arms above head; facial plethora/congestion = SVC obstruction from retrosternal goitre

7. MUSCULOSKELETAL EXAMINATION

"GALS" Screening (Gait, Arms, Legs, Spine)

Quick screen; then go system/joint-specific if abnormal.
ComponentWhat to assess
GaitSmooth, symmetric, arm swing, turns
ArmsHands (squeeze MCP joints), wrists, elbows, shoulders (behind head, behind back), cervical spine
LegsHip (passive flexion/rotation), knees (effusion - ballottement, bulge sign), ankles, subtalar joint
SpineCervical (rotation, flexion), lumbar (forward flexion - Schober's test), SI joints (sacral pressure)

Joint Examination Sequence (any joint):

  1. Look (swelling, deformity, erythema, wasting, rash)
  2. Feel (temperature, tenderness, swelling type: bony/synovial/effusion, crepitus)
  3. Move (active then passive range of motion; end-feel)
  4. Special tests (joint-specific)
  5. Function (grip strength, gait, ADLs)

8. QUICK REFERENCE: BEDSIDE DIAGNOSTIC TESTS ACROSS SYSTEMS

TestSystemPositive FindingMeaning
Shifting dullnessAbdomenDullness shiftsAscites
Murphy's signAbdomenInspiratory arrest in RUQAcute cholecystitis
Babinski signNeurologyExtensor plantarUMN lesion
Romberg's testNeurologyFalls with eyes closedPosterior column/sensory ataxia
Kernig's signNeurologyPain/resistance to knee extension with hip flexed 90°Meningism
Brudzinski's signNeurologyHips flex on neck flexionMeningism
Pulsus paradoxusCVS>10 mmHg fall in systolic on inspirationCardiac tamponade, severe asthma, PE
Kussmaul's signCVSJVP rises on inspirationConstrictive pericarditis
Hepatojugular refluxCVSJVP rises with sustained RUQ pressureRV failure
EgophonyRespiratory"EEE" heard as "AHH"Consolidation
Whispered pectoriloquyRespiratoryWhisper clearly audibleConsolidation
Tactile fremitusRespiratoryIncreased vs decreasedConsolidation vs effusion/pneumothorax

9. ORDER OF A COMPLETE GENERAL MEDICINE WARD ROUND EXAMINATION

A structured approach at the bedside:
  1. End of bed inspection: general appearance, IV lines, O2, monitoring
  2. Hands: nails, palms, asterixis, temperature, pulses
  3. Face/neck: eyes, mouth, JVP, lymph nodes, thyroid
  4. Vital signs: BP (both arms if needed), pulse, RR, SpO2, temperature
  5. CVS: precordium, heart sounds, peripheral pulses, oedema
  6. Respiratory: trachea, chest expansion, percussion, auscultation
  7. Abdomen: inspection, auscultation, percussion, palpation; offer PR
  8. Neurology (if indicated): conscious level, cranial nerves, motor, reflexes, sensation, cerebellar, gait
  9. Lymph nodes, skin: full body skin check if relevant
  10. Genitalia/hernias: if clinically indicated
  11. Fundoscopy: HTN, diabetes, raised ICP, endocarditis
  12. Urine dipstick: routine in most medical patients

Sources:
  • Harrison's Principles of Internal Medicine 22E (2025, McGraw Hill Medical) - Chapter 246 (Cardiovascular Examination), Chapter 262 (Respiratory Examination)
  • Goldman-Cecil Medicine, International Edition - Chapter on Abdominal Examination
  • Bradley and Daroff's Neurology in Clinical Practice - Chapter 1 (Neurological Examination)

Specifically on musculoskeletal examination with methods and interpretation

I now have comprehensive content across all MSK regions. Let me compile the full structured guide.

Musculoskeletal (MSK) Examination - Complete Guide

Source: Rheumatology 2-Volume Set (2022, Elsevier), Harrison's Principles of Internal Medicine 22E

CORE FRAMEWORK: LOOK - FEEL - MOVE - STRESS

Every joint, every time, in this order:
StepWhat you are assessing
LOOKSwelling, deformity, wasting, skin, attitude at rest, during movement
FEELWarmth, tenderness (location), swelling type (synovial/bony/fluid), crepitus
MOVEActive, then passive, then resisted (against resistance)
STRESSLigamentous stability, special tests

STEP 1: GENERAL SURVEY (Before Touching the Patient)

Posture (patient standing, in underwear)

  • Compare heights of: shoulders, scapulae, pelvic brim, gluteal creases
  • Inspect the spine: normal cervical lordosis, thoracic kyphosis, lumbar lordosis
  • Look at feet in neutral standing position
  • Any asymmetry = scoliosis, leg length discrepancy, joint deformity

Gait (ask them to walk across the room and back)

Gait PatternDescriptionCause
AntalgicShortened stance phase on affected side, leaning to that sidePain in any lower limb joint or bone
TrendelenburgPelvis dips to opposite side during stance on affected leg; body sways over the hipWeak hip abductors (gluteus medius), hip OA, hip fracture
High-steppingExaggerated hip and knee flexion during swing phaseFoot drop (L4/5, peroneal nerve palsy)
Leg length discrepancyTilting pelvis, knee flexion of longer legLeg length inequality
Trendelenburg test: ask patient to stand on one leg. Normally the pelvis stays level or rises slightly. If the pelvis drops to the opposite side = positive = weak hip abductors on the standing leg.

Functional MSK Screen (GALS equivalent)

Before detailed regional exam, these rapid manoeuvres screen all major regions:
ActionStructures assessed
Sit cross-legged on floorHip abduction, external rotation, flexion; knee flexion
Rise to standing (no hands)Leg extension, back extension, proximal muscle power
Bend forward to touch toesLumbar/thoracic flexion, scoliosis
Remove shoes and socksHip + knee flexion, hand + wrist function
Remove top/shirtShoulder + elbow range
Walk normallyFull gait cycle
Walk on tiptoesAnkle plantar flexion, toe extension, calf power
Walk on heelsAnkle dorsiflexion, knee extension, enthesitis
Arms extended, hands pronatedElbow extension, shoulder power
Make a fistFinger flexion
"Hands praying" positionWrist extension, elbow flexion, finger extension
Arms above head reachingShoulder flexion
Look over each shoulderCervical spine rotation

STEP 2: INTERPRETATION PRINCIPLES

Before going joint by joint, know how to interpret what you find.

Types of Swelling - How to Distinguish

Swelling TypeFeelInterpretation
Synovial thickeningBoggy, rubbery, not fluctuant, non-tender in early RASynovitis (RA, psoriatic arthritis, reactive)
Joint effusionFluctuant, ballottable, may be warmInflammation, trauma, haemarthrosis, OA
Bony swellingHard, non-tender, irregular joint lineOA (osteophytes), Heberden's/Bouchard's nodes
Bursal swellingFluctuant, outside joint line, overlies bony prominenceBursitis (olecranon, prepatellar, infrapatellar)

Inflammation vs Damage vs Mechanical

FeatureInflammatory (e.g., RA)Damage/OAMechanical/Periarticular
SwellingBoggy synovial or effusionBony enlargementBursa or tendon sheath
WarmthPresent (esp. medium joints)Mild or absentLocalised to structure
RednessRare (acute gout, septic)AbsentAbsent (unless gout)
StiffnessMorning stiffness >30-60 minShort morning stiffness <30 minNone at rest
Pain with movementAll directionsThroughout range (mechanical)One plane of movement
Passive vs activeBoth restricted equally in synovitisPassive > active usually in OAActive much more painful than passive
Key rule: Pain in ALL directions of movement = synovitis. Pain in ONE plane = localised articular or periarticular problem. Pain THROUGHOUT range = OA.

Active vs Passive vs Resisted Movement

MethodUse
ActivePatient moves joint themselves; tests integrated function; pain/restriction reflects all structures
PassiveExaminer moves the joint; isolates joint from muscle/tendon; more range than active = pain/weakness in muscle-tendon
Resisted (isometric)Joint in neutral; patient resists movement; tests tendon and enthesis specifically; pain = tendon or enthesis problem

Tenderness Location

Location of tendernessMeaning
Joint lineArticular disease (OA, inflammatory arthritis)
Periarticular (away from joint line)Bursitis, tendinitis, enthesitis
Muscle bellyMyositis, fibromyalgia
BoneFracture, osteomyelitis, metastases, Paget's disease
Vertebral body (percussion)Infection, fracture, myeloma

STEP 3: REGIONAL EXAMINATION

3.1 HANDS AND WRISTS

Position: patient seated, hands rested on a pillow, palms up then down.

LOOK

Dorsal surface:
  • Small muscle wasting: interossei wasting (guttering between tendons) = RA, ulnar nerve, T1 lesion
  • Tendon nodules: over extensor tendons = RA
  • Deformities (critical to recognise):
DeformityDescriptionCause
Ulnar deviationFingers deviate ulnar-ward at MCPsRA (MCP synovitis + ulnar drift)
Swan-neck deformityPIP hyperextension + DIP flexionRA (volar plate laxity + extensor imbalance)
Boutonnière deformityPIP flexion + DIP hyperextensionRA (central slip rupture)
Z-deformity of thumbMCP hyperextension + IP flexionRA, SLE
Heberden's nodesBony swelling at DIP jointsOA
Bouchard's nodesBony swelling at PIP jointsOA
Telescoping fingersDigits shorten and elongate (opera glass deformity)Psoriatic arthritis (arthritis mutilans)
Spindle-shaped PIP swellingFusiform synovial swelling at PIPsEarly RA
Dactylitis ("sausage digit")Entire digit swollenPsoriatic arthritis, reactive arthritis
Palmar surface:
  • Palmar erythema (liver disease, pregnancy, RA)
  • Dupuytren's contracture (flexion contracture of ring/little finger)
  • Thenar wasting (median nerve/carpal tunnel syndrome, T1)
  • Hypothenar wasting (ulnar nerve)
Skin and nails:
  • Psoriatic plaques
  • Nail pitting (>20 pits = psoriasis), onycholysis, ridging
  • Splinter haemorrhages (endocarditis, vasculitis)
  • Periungual erythema (dermatomyositis, SLE)
  • Raynaud's changes (colour, ulcers)
  • Calcinosis (systemic sclerosis)
  • Gottron's papules over MCPs/PIPs (dermatomyositis)
  • Tight, thickened, bound-down skin (systemic sclerosis - scleroderma)
Swan-neck deformity of fingers showing PIP hyperextension and DIP flexion, classic of rheumatoid arthritis

FEEL

  • Warmth: use dorsum of YOUR hand, compare both sides
  • Squeeze across all MCPs together (composite tenderness test) - positive if tender = MCP synovitis
  • Palpate each MCP individually: index finger on dorsal joint line, thumb beneath - feel for boggy synovial thickening
  • Palpate PIPs and DIPs: using "interlocking C" technique - index and thumb of both hands around joint; feel for warmth, synovitis, bony swelling
  • Palpate tendon sheaths during movement: crepitus = tenosynovitis

MOVE

  • Active: make a tight fist (all fingers should fully flex to touch palm); observe palmar blanching on release (grip strength)
  • Pinch grip: thumb to each finger individually (tip-to-tip, lateral)
  • Grip strength: patient squeezes your two fingers; grade or use dynamometer
  • Wrist: active flexion/extension; note if full extension achievable ("hands-praying" position tests bilateral wrist extension)
  • Passive wrist: flexion (normal ~80°), extension (normal ~70°), radial deviation (15°), ulnar deviation (30°)
  • Hypermobility test: passively extend 5th finger to >90° at MCP = one criterion of Beighton score

RESISTED TESTS (Tendon/Enthesis)

  • Resisted wrist extension (elbow extended) → pain at lateral epicondyle = lateral epicondylitis (tennis elbow)
  • Resisted wrist flexion → pain at medial epicondyle = medial epicondylitis (golfer's elbow)

3.2 ELBOW

Position: patient seated, examine from front and behind.

LOOK

  • Para-olecranon groove: first place to see elbow joint effusion (fills the groove, making it convex)
  • Olecranon bursa: discrete fluctuant swelling directly over olecranon = bursitis (gout, septic, trauma, RA)
  • Rheumatoid nodules: firm, non-tender, subcutaneous, over olecranon and extensor surface
  • Carrying angle: normal valgus ~10-15° women, ~5° men; increased = cubitus valgus (ulnar nerve risk); decreased = cubitus varus

FEEL

  • Lateral epicondyle: tender = lateral epicondylitis
  • Medial epicondyle: tender = medial epicondylitis; check ulnar nerve (tender, thickened) in groove posterior to medial epicondyle
  • Para-olecranon groove (either side of olecranon): synovial swelling = joint disease
  • Skin laxity: assess for hypermobility syndrome

MOVE

  • Passive extension (normal = 0°; hyperextension = hypermobility)
  • Passive flexion (normal ~145°)
  • Supination/pronation (elbows at 90°, tucked in to stabilise shoulder): normal ~90° each way; restricted in radioulnar arthritis

3.3 SHOULDER

Position: patient standing or seated, expose both shoulders fully.

LOOK

  • Asymmetry of scapulae, level of shoulders
  • Muscle wasting: deltoid (axillary nerve, C5), supraspinatus/infraspinatus fossae (suprascapular nerve, rotator cuff tear)
  • Step deformity at AC joint: ACJ disruption
  • Swelling at anterior shoulder: glenohumeral effusion

FEEL

  • Trapezius midpoint: tender spot = fibromyalgia, trapezius strain
  • Supraspinatus (just posterior to the mid-clavicle): tender = rotator cuff pathology
  • AC joint line: tender = ACJ OA, ACJ injury; step deformity
  • Bicipital groove (anterior shoulder, arm slightly externally rotated): tender = bicipital tendinitis

MOVE

Active (watch for painful arc):
  • Arms to the side, elevate in the plane of the scapula: painful arc 60-120° = rotator cuff impingement or subacromial bursitis
  • Hands behind head (abduction + external rotation) = tests external rotation and abduction
  • Hands behind back, reach up spine (adduction + internal rotation) = tests internal rotation; note highest spinal level reached (normally T6-T8)
Passive (stabilise scapula with one hand):
  • Abduction (normal 180°), flexion (180°), extension (50°), external rotation (90° with elbow bent at side), internal rotation (70°)
Resisted (impingement tests):
  • Neer's test: examiner passively forward-flexes the arm with elbow extended and forearm pronated, forcing the supraspinatus against the acromion. Pain = subacromial impingement
  • Hawkins-Kennedy test: arm forward-flexed to 90°, elbow flexed 90°, examiner forcibly internally rotates the arm. Pain = subacromial impingement
  • Empty can test (Jobe's): arm abducted 90° in scapular plane, 30° forward, thumb pointing down ("empty can"); examiner pushes down while patient resists. Weakness or pain = supraspinatus tear
  • Resisted external rotation: elbow 90° at side; patient resists internal rotation. Weakness = infraspinatus/teres minor tear
  • Speed's test: elbow extended, forearm supinated, arm at 60° flexion; resist further flexion. Bicipital groove pain = bicipital tendinitis
  • Yergason's test: elbow flexed 90°, forearm pronated; patient supinates against resistance. Bicipital groove pain = long head of biceps pathology

3.4 CERVICAL SPINE

Position: patient seated.

LOOK

  • Normal lordosis or loss/reversal (hyperextension secondary to thoracic kyphosis)
  • Head position: tilted, rotated? (torticollis)

FEEL

  • Percuss each spinous process: localised bony tenderness = fracture, infection, myeloma
  • Paraspinal muscles: spasm, tenderness (trapezius, cervical paraspinals)

MOVE (active, guide to maximum with your hands)

MovementNormal RangeKey Finding
Flexion (chin to chest)80°Reduced in spondylosis, RA, AS
Extension (look at ceiling)50°Reduced/painful = facet joint OA, spondylosis
Rotation (chin to shoulder)80° each wayFirst movement lost in AS; also C1-C2 joint
Lateral flexion (ear to shoulder)45°Reduced bilaterally = spondylosis; unilateral = acute disc
Lateral rotation and extension lost early in ankylosing spondylitis affecting the cervical spine.

STRESS / SPECIAL TESTS

  • Spurling's test (foraminal compression): tilt head to affected side + extend + apply downward pressure on crown. Reproduces radicular arm pain = cervical radiculopathy (foraminal stenosis)
  • Distraction test: lift head gently upward - relief of radicular pain = positive
Always assess neurology (C5-T1 myotomes, reflexes, dermatomal sensation) when neck pathology is suspected.

3.5 THORACIC AND LUMBAR SPINE

Position: standing first, then lying prone/supine for special tests.

LOOK

  • Kyphosis: increased thoracic kyphosis (osteoporosis, vertebral fractures, AS, Scheuermann's disease)
  • Scoliosis: lateral curvature; ask patient to bend forward - if rib hump visible on bending = structural scoliosis; if disappears = functional (postural, leg length discrepancy)
  • Loss of lumbar lordosis: muscle spasm (acute disc prolapse), AS
  • Pelvic tilt: check level of ASIS and PSIS bilaterally
  • Buttock and thigh wasting

FEEL

  • Percussion along each spinous process: localised tenderness = fracture, infection, metastases, myeloma
  • Paraspinal muscles: bilateral spasm = protective (acute disc) or chronic spondylosis

MOVE (Lumbar)

MovementNormal RangeClinical Note
Forward flexionFingers to floor / flat palmsMeasures mainly at L4-S1
Extension (arch back)~30°Painful = facet joint OA
Lateral flexion (side to side)~30° eachAsymmetric restriction = scoliosis, lateral disc
Rotation (fix pelvis with hands)~45°Tested seated
Schober's test (formal lumbar flexion measurement):
  1. Mark a point 10 cm above and 5 cm below the level of the posterior iliac spine dimples (dimples of Venus) while patient stands erect
  2. Ask patient to flex forward maximally
  3. Measure the new distance between the two marks
  4. Normal: increases by ≥5 cm (so original 15 cm should become ≥20 cm)
  5. Abnormal (<5 cm increase): restricted lumbar flexion = AS, spondylosis, lumbar OA
In normal hypermobile individuals, hands may lay flat on the floor; the Schober test specifically measures lumbar mobility, not hamstring flexibility.

STRESS / SPECIAL TESTS

Straight Leg Raise (SLR) - sciatic nerve stretch test:
  • Patient supine; examiner slowly raises the straightened leg, holding ankle
  • Normal: no pain until ~70-80°
  • Positive: sciatica (radiating pain below knee in dermatomal distribution) reproduced between 30-70° = L4, L5, or S1 nerve root compression
  • Sensitise: dorsiflex ankle at point of pain (Bragard's sign) - increases stretch on sciatic nerve, increases radicular pain
  • Crossed SLR: raising the normal leg reproduces pain in the affected leg = large central disc prolapse
Femoral Nerve Stretch Test (reverse SLR):
  • Patient prone; examiner holds ankle and passively flexes knee as far as possible
  • Positive: pain in ipsilateral anterior thigh = L2, L3, or L4 nerve root tension (high lumbar disc prolapse)
Always assess neurology in lumbar spine examination:
RootReflexMotorSensation
L3Knee jerkKnee extension (quadriceps)Anterior/medial thigh
L4Knee jerkAnkle dorsiflexion (tibialis anterior)Medial lower leg
L5NilGreat toe/ankle dorsiflexion; hip abductionLateral lower leg, dorsum of foot, great toe
S1Ankle jerkAnkle plantarflexion (gastrocnemius); eversionLateral foot, little toe

3.6 HIP

Position: patient supine on examination couch; gait already observed.

LOOK

  • Wasting of buttock or thigh muscles (disuse)
  • Leg position at rest: external rotation + shortening = fracture neck of femur; fixed flexion with external rotation = hip OA
  • Measure leg length if pelvic tilt present:
    • True leg length: ASIS to medial malleolus (structural shortening)
    • Apparent leg length: umbilicus to medial malleolus (pelvic tilt causing apparent shortening)

FEEL

  • Palpate for tenderness to locate the structure:
    • Greater trochanter: trochanteric bursitis or gluteus medius tendinopathy (lateral hip pain in women, very common)
    • Anterior hip/inguinal region: true hip joint pain (groin), hip flexor tendinopathy
    • Ischial tuberosity: hamstring enthesopathy, ischial bursitis
    • Pubic symphysis: pubic symphysitis (athletes)

MOVE

Passive movements (do not inflict pain):
MovementMethodNormal Range
FlexionKnee flexed, hip flex as far as possible; watch for contralateral hip flexing (indicates tight hip flexors = positive Thomas test)~120°
Internal rotationHip and knee flexed to 90°; hold foot and move lower leg outward (internally rotates hip)40°
External rotationHip and knee flexed 90°; move lower leg inward (externally rotates hip)40°
AbductionStabilise contralateral ASIS; straighten leg, abduct45°
AdductionCross leg over midline25°
ExtensionPatient prone (or side-lying); passively extend straightened leg20°
Internal rotation is the first movement restricted in hip joint pathology (OA, AVN, hip effusion). Reproduce the patient's pain.
Thomas Test (fixed flexion deformity of hip):
  1. Flex both hips fully (eliminates lumbar lordosis)
  2. Hold the unaffected hip in full flexion
  3. Lower the affected leg - if it cannot reach the couch flat = positive fixed flexion deformity
  4. Measure the angle from the couch = degree of fixed flexion
FABER/Patrick's Test (Flexion-ABduction-External Rotation):
  • Patient supine; place the ankle of the test leg on the opposite knee (figure-4 position)
  • Gently press down on the flexed knee while stabilising the opposite ASIS
  • Positive: hip or groin pain = hip joint pathology; SI joint pain (posterior) = sacroiliac joint pathology
Trendelenburg Test (hip abductor weakness):
  • Patient stands on one leg (affected side); observe pelvis from behind
  • Positive: pelvis drops to the contralateral side = weak gluteus medius (hip abductors) ipsilaterally
  • Causes: hip OA, superior gluteal nerve palsy, L5 radiculopathy, hip fracture, coxa vara

3.7 KNEE

Position: patient supine; stand on the affected side.

LOOK

  • Alignment:
    • Valgus (knock-knees, genu valgum) = lateral compartment OA, RA
    • Varus (bow-legs, genu varum) = medial compartment OA
  • Flexion deformity: cannot fully extend at rest = fixed flexion deformity
  • Swelling: effusion (suprapatellar pouch fullness), prepatellar bursitis, infrapatellar bursitis
  • Wasting of quadriceps (vastus medialis specifically): even small effusions inhibit VMO by reflex
  • Baker's cyst: visible or palpable in popliteal fossa (associated with knee OA, RA)

FEEL

  • Temperature: use dorsum of hand; compare both sides; warm knee = active effusion/inflammation
  • Patellar tap: compress suprapatellar pouch with one hand (to push fluid below patella), then push patella downward with two fingers of other hand; clunk = large effusion
  • Bulge sign (fluid sweep/wipe test): for small effusions; stroke medial compartment upward (emptying it), then sweep down the lateral side; watch for medial bulge appearing = fluid returning to medial compartment = positive
  • Joint line palpation: palpate medial and lateral joint lines with knee slightly flexed; tenderness = meniscus, OA, ligament
  • Collateral ligaments: medial and lateral joint lines; tender = collateral ligament injury

MOVE

  • Active: extend (should reach 0° or slight hyperextension) and flex (normal ~135°); assess end-feel
  • Passive: same ranges; note any block to full extension (locked knee = bucket handle meniscal tear)
  • Crepitus on movement: patellofemoral = fine crepitus; tibiofemoral OA = coarser

STRESS TESTS

Collateral Ligament Stress Tests:
  • Knee in slight flexion (~20-30°); stabilise thigh
  • Valgus stress (push tibia medially) = tests medial collateral ligament (MCL); opening on medial side = MCL tear
  • Varus stress (push tibia laterally) = tests lateral collateral ligament (LCL); opening on lateral side = LCL tear
Cruciate Ligament Tests:
  • Anterior Drawer Test: knee flexed 90°; sit on patient's foot; pull tibia forward. Anterior movement >5 mm = ACL tear
  • Lachman's Test (more sensitive than anterior drawer): knee flexed 20°; stabilise femur with one hand, pull tibia anteriorly with other. Soft end-feel + anterior translation = ACL tear
  • Posterior Drawer Test: same position as anterior drawer; push tibia posteriorly. Posterior movement = PCL tear
Meniscal Tests:
  • McMurray's Test: patient supine, hip and knee flexed maximally; examiner holds heel and knee, rotate tibia externally while extending knee (tests medial meniscus); then internally while extending (tests lateral meniscus). Positive: palpable/audible click + joint line pain = meniscal tear
  • Apley's Test (grinding): patient prone, knee flexed 90°; compress tibia onto femur (press down on heel) and rotate. Pain = meniscal tear. Then distract (pull heel up) and rotate - pain = ligamentous problem

3.8 FOOT AND ANKLE

Position: patient standing and walking first, then supine.

LOOK (standing + walking)

  • Longitudinal arch: normally raised on medial side; pes planus (flat foot) = loss of arch; pes cavus (high arch) = hereditary neuropathy (CMT), polio
  • Heel alignment: valgus (eversion, pronation) = pes planus; varus (inversion, supination) = pes cavus
  • MTP joints: swelling separating toes ("daylight sign") = MTP synovitis (RA)
  • Hallux valgus: lateral deviation of great toe at MTP joint (bunion) = OA, RA
  • Claw toes: extension at MTP + flexion at PIP and DIP
  • Hammer toe: PIP flexion + MTP extension (usually 2nd toe)
  • Callosities under metatarsal heads = pressure from subluxed MTP joints (RA)

FEEL

  • Squeeze across all MTPs together: composite tenderness = MTP synovitis (RA, psoriatic)
  • Palpate individual MTPs: each joint line for swelling and tenderness
  • Achilles tendon: tender insertional pain = enthesitis (AS, reactive arthritis, psoriatic); tender mid-substance = Achilles tendinopathy
  • Plantar fascia origin (medial calcaneal tubercle): tender = plantar fasciitis
  • Lateral ligaments (anterior talofibular + calcaneofibular): tender after inversion sprain

MOVE

  • Ankle: active dorsiflexion (normal ~20°) and plantarflexion (normal ~50°)
  • Subtalar joint (hindfoot): grasp heel between thumb and index finger; move heel medially (inversion, normal ~30°) and laterally (eversion, ~20°); restricted = subtalar OA, AS
  • Midtarsal joint (Chopart's): hold heel fixed, rotate forefoot; restricted = midtarsal OA
  • MTPs: passively flex and extend each toe; dorsiflexion of great toe >70° = normal

3.9 SACROILIAC JOINTS AND PELVIS

LOOK

  • Assess from behind: pelvic tilt, buttock wasting, dimples of Venus (posterior iliac spines)

FEEL

  • Direct sacral pressure (sit on sacrum): pain = SI joint inflammation or sacral fracture
  • FABER test (as described in Hip section): posterior pain = SI pathology

STRESS TESTS

  • FABER (Patrick's test): described above
  • FADIR test: hip Flexion-ADduction-Internal Rotation; hip or posterior pain = posterior impingement, SI joint, piriformis
  • Pelvic springing (distraction and compression): apply downward pressure on both ASIS simultaneously (springing the SI joints); pain = SI joint disease

STEP 4: INTERPRETING THE PATTERN - WHAT DOES THE DISTRIBUTION TELL YOU?

This is what transforms an examination from a collection of findings into a diagnosis.

Number of Joints

PatternDistributionThink of
Monoarthritis1 jointSeptic arthritis (exclude first!), crystal arthropathy (gout, pseudogout), trauma, haemarthrosis
Oligoarthritis2-4 joints, asymmetricPsoriatic arthritis, reactive arthritis, enteropathic arthritis, early RA
Polyarthritis≥5 jointsRA (symmetric, small joints), psoriatic arthritis (asymmetric), OA (DIP/PIP/1st CMC), SLE, viral arthritis

Joint Size

Predominant involvementThink of
Small joints (MCP, PIP, MTP, wrists)RA, psoriatic arthritis, early OA
Large joints (knees, hips, shoulders)OA, gout (can affect large joints), calcium pyrophosphate disease
Predominantly axial (spine + SI joints)Ankylosing spondylitis, psoriatic arthritis, reactive arthritis, enteropathic arthritis

Symmetry

PatternCondition
Symmetric (both MCPs, both wrists)RA, SLE
AsymmetricPsoriatic arthritis, reactive arthritis, gout
Predominantly DIP involvementOA (Heberden's nodes), psoriatic arthritis
MCP + PIP (sparing DIP)RA
DIP + 1st CMCOA

The "Hand at a Glance" Diagnoses

FeatureDiagnosis
MCP ulnar deviation + swan-neck/boutonnière + wrist synovitisRheumatoid arthritis
DIP involvement + nail pitting/onycholysis + asymmetricPsoriatic arthritis
Heberden's nodes (DIP) + Bouchard's nodes (PIP) + 1st CMC squaringOA
Tophi (chalky white deposits) over joints + acute monoarthritis (1st MTP)Gout
Raynaud's + puffy fingers + tight skin + calcinosisSystemic sclerosis
Gottron's papules over MCPs + proximal myopathy + heliotrope rashDermatomyositis
Dactylitis (sausage digit)Psoriatic or reactive arthritis

STEP 5: HYPERMOBILITY - BEIGHTON SCORE

Test in any patient with widespread joint pain and "double-jointed" history.
ManoeuvrePoints (1 per side, except 1)
Passive hyperextension of 5th finger >90°1 point each side = 2
Passive apposition of thumb to forearm1 point each side = 2
Hyperextension of elbow >10°1 point each side = 2
Hyperextension of knee >10°1 point each side = 2
Touch floor with palms flat (knees straight)1 point = 1
Total/9
Score ≥5/9 = generalised hypermobility. Combined with joint pain = Benign Joint Hypermobility Syndrome (now termed Hypermobile Ehlers-Danlos Syndrome in the spectrum).

STEP 6: PAIN CHARACTERISATION SUMMARY

Pain TypeCharacteristicsCause
ArticularPain in all directions; swelling at joint line; morning stiffnessSynovitis (RA, PsA), crystal, OA
PeriarticularOne plane of active movement painful; passive full ROM; palpation of structure painfulTendinitis, bursitis, enthesitis
NeurogenicDermatomal/nerve territory; dysaesthesia; Tinel's sign positive; normal local joint examRadiculopathy, carpal tunnel, ulnar syndrome
ReferredNormal local joint exam; uncharacteristic pattern; associated visceral symptomsHip disease referred to knee, cardiac to shoulder
Widespread/central"All over"; tender points; sleep disturbance; normal inflammatory markers and imagingFibromyalgia

Source: Rheumatology, 2-Volume Set (2022, Elsevier); Harrison's Principles of Internal Medicine 22E (2025, McGraw Hill Medical)
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