Brachial fistula and sinus

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branchial cleft fistula sinus neck anatomy diagram

This composite of three images illustrates a surgical resection of a branchial pouch sinus (fourth branchial cleft fistula). 

Panel A is an endoscopic view of the piriform fossa, showing a metal probe (black arrow) inserted into the internal opening (white arrow) of the fistula tract. 

Panels B and C are intraoperative clinical photographs of an open neck dissection. Panel B shows the surgical field with labeled anatomical structures: the thyroid gland (Th), the fistula (F) being retracted, the recurrent laryngeal nerve (RLN) visualized as a thin white strand, and the carotid artery (CA) deeper in the field. Panel C demonstrates the completed tracing and excision of the fistula (F) using the metal probe as a guide. The image highlights the proximity of the fistula to critical neurovascular structures and the thyroid gland, emphasizing the importance of careful dissection to preserve the RLN and CA during the removal of the tract and associated scar tissue.

This composite of three images illustrates a surgical resection of a branchial pouch sinus (fourth branchial cleft fistula). Panel A is an endoscopic view of the piriform fossa, showing a metal probe (black arrow) inserted into the internal opening (white arrow) of the fistula tract. Panels B and C are intraoperative clinical photographs of an open neck dissection. Panel B shows the surgical field with labeled anatomical structures: the thyroid gland (Th), the fistula (F) being retracted, the recurrent laryngeal nerve (RLN) visualized as a thin white strand, and the carotid artery (CA) deeper in the field. Panel C demonstrates the completed tracing and excision of the fistula (F) using the metal probe as a guide. The image highlights the proximity of the fistula to critical neurovascular structures and the thyroid gland, emphasizing the importance of careful dissection to preserve the RLN and CA during the removal of the tract and associated scar tissue.

This clinical diagnostic image shows a direct laryngoscopic view of the right pyriform sinus apex in a patient with a suspected branchial cleft cyst. Centrally, the image demonstrates a small, dark, oval fistulous tract opening. The immediate perifistular tissue exhibits a blanched, white-to-light-gray appearance, characteristic of chemical cauterization following the application of 40% trichloroacetic acid (TCA). The surrounding pharyngeal mucosa is reddish-pink with a moist, glistening texture. This visual represents the intraoperative endpoint of chemocauterization for the management of a branchial cleft fistula, where the goal is to induce mucosal inflammation and subsequent fibrosis to achieve tract closure. The anatomical context is critical for otolaryngologists in identifying and treating congenital neck anomalies through endoscopic approaches.

This clinical diagnostic image shows a direct laryngoscopic view of the right pyriform sinus apex in a patient with a suspected branchial cleft cyst. Centrally, the image demonstrates a small, dark, oval fistulous tract opening. The immediate perifistular tissue exhibits a blanched, white-to-light-gray appearance, characteristic of chemical cauterization following the application of 40% trichloroacetic acid (TCA). The surrounding pharyngeal mucosa is reddish-pink with a moist, glistening texture. This visual represents the intraoperative endpoint of chemocauterization for the management of a branchial cleft fistula, where the goal is to induce mucosal inflammation and subsequent fibrosis to achieve tract closure. The anatomical context is critical for otolaryngologists in identifying and treating congenital neck anomalies through endoscopic approaches.

This clinical photograph provides an intraoperative view of the surgical excision of a branchial fistula tract in the right neck. The operative field is exposed through a surgical incision, with drapes and retractors maintaining visibility. A gloved finger and surgical forceps are seen manipulating the tissues. Two key structures are labeled: 'TG' (Thyroid Gland) and 'PS' (Pyriform Sinus). A distinct, elongated, fibrous fistula tract is clearly visible, extending from the superior pole of the right thyroid gland toward the right pyriform sinus. The thyroid tissue appears hemorrhagic and partially dissected, reflecting the surgical manipulation required to isolate the tract. The image illustrates the complex anatomical relationship between the branchial fistula and adjacent endocrine and pharyngeal structures, specifically highlighting the pathway where a fourth branchial pouch sinus typically traverses. This material is educationally relevant for otorhinolaryngology and endocrine surgery trainees to understand the surgical anatomy of congenital neck fistulas.

This clinical photograph provides an intraoperative view of the surgical excision of a branchial fistula tract in the right neck. The operative field is exposed through a surgical incision, with drapes and retractors maintaining visibility. A gloved finger and surgical forceps are seen manipulating the tissues. Two key structures are labeled: 'TG' (Thyroid Gland) and 'PS' (Pyriform Sinus). A distinct, elongated, fibrous fistula tract is clearly visible, extending from the superior pole of the right thyroid gland toward the right pyriform sinus. The thyroid tissue appears hemorrhagic and partially dissected, reflecting the surgical manipulation required to isolate the tract. The image illustrates the complex anatomical relationship between the branchial fistula and adjacent endocrine and pharyngeal structures, specifically highlighting the pathway where a fourth branchial pouch sinus typically traverses. This material is educationally relevant for otorhinolaryngology and endocrine surgery trainees to understand the surgical anatomy of congenital neck fistulas.

This clinical diagnostic image shows an endoscopic view of the left piriform sinus, located within the hypopharynx. The mucosa is predominantly reddish-pink and demonstrates prominent superficial vascularization. At the apex of the piriform sinus, a distinct, abnormal opening is visible, representing a branchial cleft fistula or sinus tract. The orifice of the fistula appears as a dark, circular indentation with irregular, slightly elevated, and erythematous margins, suggesting localized chronic inflammation or tissue remodeling. The surrounding mucosal texture is uneven, transitioning from smooth areas to more granular surfaces near the pathological opening. This visual finding is characteristic of a congenital branchial anomaly, specifically a third or fourth branchial cleft remnant, which typically presents with recurrent neck infections or abscesses. The image serves as a key educational reference for identifying anatomical landmarks and pathological findings during direct laryngoscopy in Otolaryngology (ENT).

This clinical diagnostic image shows an endoscopic view of the left piriform sinus, located within the hypopharynx. The mucosa is predominantly reddish-pink and demonstrates prominent superficial vascularization. At the apex of the piriform sinus, a distinct, abnormal opening is visible, representing a branchial cleft fistula or sinus tract. The orifice of the fistula appears as a dark, circular indentation with irregular, slightly elevated, and erythematous margins, suggesting localized chronic inflammation or tissue remodeling. The surrounding mucosal texture is uneven, transitioning from smooth areas to more granular surfaces near the pathological opening. This visual finding is characteristic of a congenital branchial anomaly, specifically a third or fourth branchial cleft remnant, which typically presents with recurrent neck infections or abscesses. The image serves as a key educational reference for identifying anatomical landmarks and pathological findings during direct laryngoscopy in Otolaryngology (ENT).

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Branchial Fistula and Sinus

Note: The correct term is branchial (from the branchial/pharyngeal arch apparatus), not "brachial" (which refers to the arm).

Definitions

TermDefinition
Branchial fistulaA congenital skin-lined tract with two openings - an internal opening in the pharynx and an external opening on the neck skin
Branchial sinusHas only one opening - either internal (into the pharynx) or more commonly external (on the neck skin), with no communication at the other end
Branchial cystA closed remnant with no opening at all

Embryological Basis

During the 4th week of intrauterine life, six branchial arches develop as neural crest cells migrate cranially. During the 5th week, the second branchial arch grows downward to cover the 3rd and 4th branchial clefts, forming the cervical sinus of His. This sinus normally obliterates completely. Failure of obliteration creates the potential for a tract communicating with the:
  • 2nd branchial pouch - in the tonsillar fossa (most common)
  • 3rd branchial pouch - in the pyriform sinus/larynx area
  • 4th branchial pouch - in the lower pyriform fossa
The external (cutaneous) openings of branchial sinuses and fistulae lie anterior to the anterior border of the sternocleidomastoid muscle. All tracts lie deep to the platysma muscle (a second arch derivative).
  • Scott-Brown's Otorhinolaryngology Head & Neck Surgery, Vol 2
  • KJ Lee's Essential Otolaryngology

Classification by Arch of Origin

Second Branchial Anomalies (most common ~95%)

External opening: Anterior border of the SCM at the junction of the middle and lower thirds
Course of the tract:
  1. Deep to second arch derivatives (CN VII, external carotid artery)
  2. Superficial to third arch derivatives (stylopharyngeus, CN IX, internal carotid artery)
  3. Superficial to CN XII
  4. In close relation with but superficial to the carotid sheath
  5. Pierces the middle constrictor muscle, deep to the stylohyoid ligament
  6. Internal opening: Anterior aspect of the tonsillar fossa (slit-like)

Third Branchial Anomalies (rare)

  • External opening: Anterior to SCM, low in the neck
  • Deep to the internal carotid artery and CN IX
  • Pierces the thyrohyoid membrane above the internal branch of the superior laryngeal nerve
  • Opens into the pyriform fossa

Fourth Branchial Anomalies (rare)

  • Also opens into the lower pyriform sinus or larynx
  • Third and fourth anomalies are difficult to distinguish clinically; often present with recurrent thyroid infections

First Branchial Anomalies

  • Work Type I: Preauricular, parallel to the EAC
  • Work Type II: Through the parotid gland, ending at the bony-cartilaginous EAC junction (angle of mandible)
  • Variable relation to the facial nerve (deep, superficial, or between branches) - making surgery hazardous
  • Schwartz's Principles of Surgery, 11th Ed.
  • KJ Lee's Essential Otolaryngology

Clinical Features

  • Most patients are young infants or children presenting with a discharging sinus in the neck
  • The external opening appears just in front of the lower third of the anterior border of the sternomastoid
  • Discharge is mucoid or mucopurulent
  • The tract may intermittently become infected, forming a neck abscess
  • Some patients notice increased discharge during upper respiratory tract infections
  • A complete fistula extends all the way to the supra-tonsillar fossa
The hallmark position of a branchial fistula is shown below:
Branchial fistula tract - intraoperative view showing the tract emerging between constrictor muscles
Branchial fistula tract emerging between the constrictor muscles, deep to the omohyoid muscle - Scott-Brown's

Investigations

  1. Clinical diagnosis - position and nature of the opening is often diagnostic
  2. Fistulogram / CT fistulogram - inject radio-opaque dye (e.g., Uropac) into the external opening to delineate the tract length and differentiate sinus from fistula; a complete fistula will extend to the supra-tonsillar fossa
  3. Contrast swallow - useful for 3rd/4th arch anomalies with pyriform sinus involvement
  4. Endoscopy - can visualize internal opening in the pyriform sinus for 3rd/4th arch lesions
  5. Ultrasound + CT/MRI - for surgical planning in complex cases

Surgical Treatment

Surgical excision is the treatment of choice.
Technique (stepladder/staircase approach):
  1. An elliptical incision is made around the external opening at the skin
  2. The tract is followed upward as high as possible
  3. A second (stepladder) incision is made higher up in a skin crease to allow further dissection
  4. The entire tract is excised, including the internal opening if accessible
Key hazards:
  • Facial nerve (particularly for 1st arch lesions - the tract may be deep, superficial, or between branches of the nerve; intraoperative nerve monitoring is advised)
  • Internal carotid artery and external carotid artery
  • Hypoglossal nerve (CN XII), Glossopharyngeal nerve (CN IX)
  • Recurrent laryngeal nerve (for 3rd/4th arch lesions)
Important: Surgery should be performed when the tract is not infected (elective setting). Infected sinuses should be treated with antibiotics first and excision deferred.
Below is an intraoperative view of surgical excision:
Fourth branchial fistula surgical excision - endoscopic and open views showing proximity to RLN and carotid artery
Surgical resection of a 4th branchial cleft fistula: Panel A shows the internal piriform sinus opening on endoscopy; Panels B & C show the open neck dissection with the fistula (F) in relation to the thyroid (Th), recurrent laryngeal nerve (RLN), and carotid artery (CA).

Summary Table

Feature2nd Arch Fistula3rd Arch Fistula4th Arch Fistula
FrequencyMost common (~95%)RareRare
External openingAnt. SCM (mid-lower junction)Low in neckLow in neck
Internal openingTonsillar fossaPyriform sinusLower pyriform/larynx
Key nerve riskCN IX, XIICN IX, SLNRLN
Passes relative to ICASuperficialDeep to ICADeep to ICA
Typical presentationNeck discharge from infancyRecurrent neck abscessRecurrent thyroiditis

References:
  • Scott-Brown's Otorhinolaryngology Head & Neck Surgery, Vol 2 - Branchial Fistulae and Sinuses section
  • KJ Lee's Essential Otolaryngology - Embryology and Derivatives of the Pouches
  • Schwartz's Principles of Surgery, 11th Ed. - Benign Neck Masses
  • S. Das - A Manual on Clinical Surgery, 13th Ed. - Physical Examination of the Neck

Branchial cyst

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branchial cyst neck clinical presentation CT scan

This composite image consists of a clinical photograph and a diagnostic CT scan illustrating a branchial cleft cyst in the neck. (A) A clinical photograph showing the left side of a patient's neck, where a large, prominent mass is visibly protruding from the skin in the upper cervical region. The overlying skin appears intact without obvious erythema. (B) An axial non-contrast CT scan of the neck at the level of the cervical vertebrae. It reveals a well-circumscribed, hypodense, ovoid mass (indicated by a white arrow) located on the left lateral aspect of the neck, deep to the platysma and lateral to the carotid sheath. The low-density center is characteristic of fluid-filled cystic structures. The lesion is located inferior to the parotid gland and anterior to the sternocleidomastoid muscle. The case illustrates the classic presentation of a branchial cleft cyst, which in this clinical context was diagnosed as a primary branchial cleft carcinoma (squamous cell carcinoma).

This composite image consists of a clinical photograph and a diagnostic CT scan illustrating a branchial cleft cyst in the neck. (A) A clinical photograph showing the left side of a patient's neck, where a large, prominent mass is visibly protruding from the skin in the upper cervical region. The overlying skin appears intact without obvious erythema. (B) An axial non-contrast CT scan of the neck at the level of the cervical vertebrae. It reveals a well-circumscribed, hypodense, ovoid mass (indicated by a white arrow) located on the left lateral aspect of the neck, deep to the platysma and lateral to the carotid sheath. The low-density center is characteristic of fluid-filled cystic structures. The lesion is located inferior to the parotid gland and anterior to the sternocleidomastoid muscle. The case illustrates the classic presentation of a branchial cleft cyst, which in this clinical context was diagnosed as a primary branchial cleft carcinoma (squamous cell carcinoma).

This dual-panel diagnostic image presents clinical imaging of the head and neck, specifically evaluating a suspected first branchial cleft cyst. Image (a) is a coronal CT scan of the temporal bones and skull base, highlighting a congenital anomaly: a bony canal (fistulous tract) measuring approximately 12.21 mm. This canal is situated in the deep portion of the tympanic bone, medial to the facial nerve and originating from the pre-tympanic region of the external auditory canal. Image (b) is a coronal T2-weighted MRI scan of the same patient, revealing a large, hyperintense, well-circumscribed parapharyngeal cyst in the left peri-tonsillar region. The cyst measures approximately 40.09 mm in its craniocaudal dimension. Together, these images illustrate the characteristic multi-component presentation of branchial cleft anomalies, involving both a cartilaginous/bony tract near the ear and a deeper soft tissue cystic component in the parapharyngeal space. The imaging modality and precise measurements are essential for pre-operative planning in otolaryngology to avoid injury to the adjacent facial nerve and carotid vasculature.

This dual-panel diagnostic image presents clinical imaging of the head and neck, specifically evaluating a suspected first branchial cleft cyst. Image (a) is a coronal CT scan of the temporal bones and skull base, highlighting a congenital anomaly: a bony canal (fistulous tract) measuring approximately 12.21 mm. This canal is situated in the deep portion of the tympanic bone, medial to the facial nerve and originating from the pre-tympanic region of the external auditory canal. Image (b) is a coronal T2-weighted MRI scan of the same patient, revealing a large, hyperintense, well-circumscribed parapharyngeal cyst in the left peri-tonsillar region. The cyst measures approximately 40.09 mm in its craniocaudal dimension. Together, these images illustrate the characteristic multi-component presentation of branchial cleft anomalies, involving both a cartilaginous/bony tract near the ear and a deeper soft tissue cystic component in the parapharyngeal space. The imaging modality and precise measurements are essential for pre-operative planning in otolaryngology to avoid injury to the adjacent facial nerve and carotid vasculature.

Diagnostic axial CT scan of the neck with contrast demonstrating a large, multiloculated cystic lesion in the left parapharyngeal and cervical space. The image series shows a hypoattenuating (fluid-density) mass indicated by white arrows, characterized by thin, internal enhancing septae. Anatomically, the lesion extends vertically from the level of the mandible down to the C7 vertebral level and the superior mediastinum. It is situated posteromedial to the left sternocleidomastoid muscle, displacing adjacent vascular structures. The clinical presentation is highly suggestive of a branchial cleft cyst or an ectopic cervical thymic cyst. This imaging highlights key diagnostic features of deep neck cystic masses, including internal architecture, density, and spatial relationship to cervical fascia and major vessels, essential for surgical planning and differential diagnosis in otolaryngology and radiology.

Diagnostic axial CT scan of the neck with contrast demonstrating a large, multiloculated cystic lesion in the left parapharyngeal and cervical space. The image series shows a hypoattenuating (fluid-density) mass indicated by white arrows, characterized by thin, internal enhancing septae. Anatomically, the lesion extends vertically from the level of the mandible down to the C7 vertebral level and the superior mediastinum. It is situated posteromedial to the left sternocleidomastoid muscle, displacing adjacent vascular structures. The clinical presentation is highly suggestive of a branchial cleft cyst or an ectopic cervical thymic cyst. This imaging highlights key diagnostic features of deep neck cystic masses, including internal architecture, density, and spatial relationship to cervical fascia and major vessels, essential for surgical planning and differential diagnosis in otolaryngology and radiology.

This diagnostic axial CT scan of the neck with contrast demonstrates an ill-defined, heterogeneous lesion in the left paratracheal soft tissue. A white arrow points to the primary pathology: a fourth branchial cleft cyst showing as a hypodense, fluid-filled area with rim enhancement, suggesting inflammation or infection. Key anatomical landmarks visible include the central air-filled trachea (dark circular structure) and the cervical vertebra (bright white structure posterior to the airway). The image captures the characteristic fistulous tract associated with this congenital anomaly, which is seen extending from the paratracheal region toward the left pyriform sinus. The lesion is located medial to the vascular structures of the carotid sheath and lateral to the trachea, illustrating the typical course of a fourth branchial arch remnant. This image is used to teach medical students and radiology residents the diagnostic presentation of a rare branchial cleft anomaly and its anatomical relationship to the upper aerodigestive tract.

This diagnostic axial CT scan of the neck with contrast demonstrates an ill-defined, heterogeneous lesion in the left paratracheal soft tissue. A white arrow points to the primary pathology: a fourth branchial cleft cyst showing as a hypodense, fluid-filled area with rim enhancement, suggesting inflammation or infection. Key anatomical landmarks visible include the central air-filled trachea (dark circular structure) and the cervical vertebra (bright white structure posterior to the airway). The image captures the characteristic fistulous tract associated with this congenital anomaly, which is seen extending from the paratracheal region toward the left pyriform sinus. The lesion is located medial to the vascular structures of the carotid sheath and lateral to the trachea, illustrating the typical course of a fourth branchial arch remnant. This image is used to teach medical students and radiology residents the diagnostic presentation of a rare branchial cleft anomaly and its anatomical relationship to the upper aerodigestive tract.

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Branchial Cyst

Definition

A branchial cyst is a congenital, non-tender, fluctuant cystic swelling of the neck arising from remnants of the branchial (pharyngeal) cleft apparatus. Unlike a branchial sinus or fistula, it has no external or internal opening - it is a closed cyst. The word "branchial" derives from the Greek bragchia, meaning gills.
Branchial anomalies account for up to 19% of all paediatric cervical masses, yet paradoxically, the cysts rarely present at birth - the peak incidence is in the 2nd to 3rd decade of life.

Aetiology / Theories of Origin

Four competing theories exist:
TheoryBasisArgument Against
Branchial apparatus theoryRemnants of pharyngeal pouches or branchial clefts (3rd-8th week of gestation)Cysts should present at birth; they don't
Cervical sinus theoryRemnants of the cervical sinus of His (formed when 2nd arch grows down to cover 3rd/4th clefts)Most widely accepted
Thymopharyngeal duct theoryRemnants of thymus-3rd pouch connectionNo cyst ever found deep to thyroid; duct never identified
Inclusion theoryEpithelial inclusions within lymph nodesExplains why cysts have lymphoid walls, absent in neonates, peak in adults - most favoured
The inclusion theory is supported by the fact that 80% of branchial cysts have lymphoid tissue with germinal centres in their outer wall.
  • Scott-Brown's Otorhinolaryngology Head & Neck Surgery, Vol 2

Pathology

FeatureDetail
LiningStratified squamous epithelium (90%); pseudostratified columnar / respiratory epithelium (10%)
WallFibrous with lymphoid tissue and prominent germinal centres (80% of cases)
ContentsStraw-coloured / golden-yellow fluid containing cholesterol crystals, fat globules, and desquamated epithelial cells
SizeUsually 2-10 cm in diameter; typically 5-10 cm
Malignant transformationRarely occurs; most cystic SCCs in the neck are metastases from upper aerodigestive tract cancers
  • Robbins & Cotran Pathologic Basis of Disease
  • S. Das - Manual on Clinical Surgery, 13th Ed.

Site and Presentation

  • 60% are in the upper third of the neck, at the anterior border of the sternocleidomastoid muscle (specifically at the junction of its upper and middle thirds, where the posterior belly of digastric crosses)
  • Classically described as being half in front and half deep to the sternomastoid
  • Long axis runs forwards and downwards
  • Presents as a smooth, fluctuant, non-tender swelling - ovoid in shape
  • 80% present as a persistent swelling; 20% are intermittent
  • 70% feel cystic; up to 30% may feel solid (tense cyst)
  • ~40% have a prior history of URTI before noticing the mass
  • Transillumination is usually negative (content is thick/turbid)
  • Does NOT move on swallowing (not attached to larynx/trachea)
  • Regional lymph nodes are NOT enlarged in an uncomplicated cyst
Complication: The cyst may become infected, causing erythema, tenderness, and abscess formation with risk of rupture.
  • Bailey and Love's Short Practice of Surgery, 28th Ed.

Imaging

Ultrasound:
Ultrasound of second branchial cleft cyst - avascular pseudosolid mass at level 2 of the neck
Ultrasound showing an avascular, pseudosolid right level 2 mass - second branchial cleft cyst (Scott-Brown's)
  • Range from anechoic simple cyst with posterior enhancement to pseudosolid / heterogeneous with debris and septae
  • If a medial beak is seen pointing toward the pharynx, CT/MRI is warranted to exclude a sinus or fistula
CT:
Axial contrast-enhanced CT showing a septated, thick-walled right level 2 infected branchial cleft cyst displacing the submandibular gland anteriorly
Axial CECT: septated, thick-walled right level 2 branchial cleft cyst (infected) displacing submandibular gland anteriorly, deep to sternomastoid - Scott-Brown's
  • Classic: homogeneous low-attenuation mass with thin wall
  • Infected: ill-defined, heterogeneous, thick-walled with debris and septae
  • MRI: high T2, low T1 signal
  • Scott-Brown's Otorhinolaryngology Head & Neck Surgery

Diagnosis / Investigations

  1. Clinical diagnosis - characteristic site, age, and feel
  2. FBC (baseline)
  3. Ultrasound + FNAC - acellular fluid with cholesterol crystals on microscopy; this is diagnostic. (Caution: squamous debris may be misread as malignancy)
  4. CT / MRI - for large cysts, surgical planning, or when a medial beak is seen
  5. PET-CT - if malignancy (metastatic SCC) cannot be excluded, especially in patients over 40 who are smokers/drinkers
Key clinical rule: In any patient over 35 years of age, a cystic neck mass must be treated as metastatic SCC until proven otherwise. HPV-related oropharyngeal SCC commonly presents as a cystic nodal metastasis mimicking a branchial cyst.

Differential Diagnosis

ConditionDifferentiating feature
Cervical lymphadenopathy (TB cold abscess)Palpable regional nodes, systemic features
Cystic hygroma (lymphangioma)Brilliantly transilluminant, multilocular, infants
Carotid body tumourTransmitted pulsation, bruit, at carotid bifurcation
Metastatic cystic SCCAge >35, smoker, find primary in oropharynx
Thyroglossal cystMidline, moves on swallowing and tongue protrusion
Dermoid cystMidline, doughy

Surgical Treatment

Surgical excision is the treatment of choice. Indications:
  • Tendency to become infected
  • Increasing size causing discomfort or cosmetic deformity
  • Pressure symptoms
Technique:
  1. Transverse cervical skin crease incision over the cyst
  2. Platysma incised; sub-platysmal flaps elevated
  3. Cervical fascia incised along the anterior border of SCM, which is retracted laterally
  4. Cyst identified and dissected from fascial attachments without rupturing the wall
  5. Carotid sheath and contents identified and protected
  6. Cyst passes superficial to CN IX and CN XII (hypoglossal), deep to the posterior belly of digastric
  7. Complete excision - the "tail" of the cyst may need dissection from the parotid gland or parapharyngeal space
Nerves at risk:
  • Marginal branch of the facial nerve (CN VII)
  • Hypoglossal nerve (CN XII)
  • Vagus nerve (CN X)
  • Spinal accessory nerve (CN XI)
  • Glossopharyngeal nerve (CN IX)
Surgery is best performed when the cyst is quiescent (not infected).

Branchiogenic Carcinoma (rare)

A very rare carcinoma arising from branchial cleft remnants. Diagnosis is largely by exclusion - only considered after exhaustive search for a primary in the mouth, tongue, nasopharynx, larynx, thyroid, and aerodigestive tract yields nothing. Most "branchiogenic carcinomas" in older literature were actually cystic metastatic SCCs.

References:
  • Scott-Brown's Otorhinolaryngology Head & Neck Surgery, Vol 2 - Branchial Cysts section
  • Bailey and Love's Short Practice of Surgery, 28th Ed.
  • Robbins & Cotran Pathologic Basis of Disease
  • S. Das - A Manual on Clinical Surgery, 13th Ed.
  • KJ Lee's Essential Otolaryngology
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