#!/usr/bin/env python3
"""
INICET Medicine PYQ - System-wise PDF Generator
Covers: Cardiology, Pulmonology, Nephrology, Hematology,
        Gastroenterology, Hepatology, Urology
Years: Nov 2020 – May 2026
"""

from reportlab.lib.pagesizes import A4
from reportlab.lib.styles import getSampleStyleSheet, ParagraphStyle
from reportlab.lib.colors import HexColor, black, white
from reportlab.lib.units import cm, mm
from reportlab.platypus import (
    SimpleDocTemplate, Paragraph, Spacer, Table, TableStyle,
    PageBreak, HRFlowable, KeepTogether
)
from reportlab.lib.enums import TA_CENTER, TA_LEFT, TA_JUSTIFY
from reportlab.lib import colors

OUTPUT = "/home/daytona/workspace/inicet-medicine-pyq/INICET_Medicine_PYQ_Systemwise.pdf"

# ─── Colour palette ────────────────────────────────────────────────────────────
C_NAVY      = HexColor("#0D2B55")
C_TEAL      = HexColor("#1A7F8E")
C_ORANGE    = HexColor("#E87722")
C_GOLD      = HexColor("#F5B942")
C_LIGHTBLUE = HexColor("#D6EAF8")
C_LIGHTGREY = HexColor("#F4F6F7")
C_GREEN     = HexColor("#1E8449")
C_RED       = HexColor("#C0392B")
C_DARKGREY  = HexColor("#2C3E50")

# ─── Styles ────────────────────────────────────────────────────────────────────
styles = getSampleStyleSheet()

TITLE_STYLE = ParagraphStyle("Title",
    fontSize=28, leading=34, textColor=white,
    fontName="Helvetica-Bold", alignment=TA_CENTER, spaceAfter=4)

SUBTITLE_STYLE = ParagraphStyle("Subtitle",
    fontSize=14, leading=18, textColor=C_GOLD,
    fontName="Helvetica-BoldOblique", alignment=TA_CENTER, spaceAfter=2)

CHAPTER_STYLE = ParagraphStyle("Chapter",
    fontSize=18, leading=24, textColor=white,
    fontName="Helvetica-Bold", alignment=TA_CENTER, spaceBefore=2, spaceAfter=2)

SECTION_STYLE = ParagraphStyle("Section",
    fontSize=13, leading=17, textColor=C_NAVY,
    fontName="Helvetica-Bold", spaceBefore=10, spaceAfter=4)

HOTSPOT_STYLE = ParagraphStyle("Hotspot",
    fontSize=11, leading=15, textColor=C_DARKGREY,
    fontName="Helvetica-Bold", spaceBefore=6, spaceAfter=3)

Q_STYLE = ParagraphStyle("Question",
    fontSize=10.5, leading=15, textColor=C_DARKGREY,
    fontName="Helvetica-Bold", spaceBefore=8, spaceAfter=3, leftIndent=6)

OPT_STYLE = ParagraphStyle("Option",
    fontSize=10, leading=14, textColor=HexColor("#2C3E50"),
    fontName="Helvetica", leftIndent=20, spaceAfter=1)

ANS_STYLE = ParagraphStyle("Answer",
    fontSize=10, leading=14, textColor=C_GREEN,
    fontName="Helvetica-Bold", leftIndent=20, spaceAfter=6)

NOTE_STYLE = ParagraphStyle("Note",
    fontSize=9.5, leading=13, textColor=C_TEAL,
    fontName="Helvetica-Oblique", leftIndent=20, spaceAfter=4)

BODY_STYLE = ParagraphStyle("Body",
    fontSize=10, leading=14, textColor=C_DARKGREY,
    fontName="Helvetica", spaceBefore=2, spaceAfter=2)

TAG_STYLE = ParagraphStyle("Tag",
    fontSize=9, leading=12, textColor=C_ORANGE,
    fontName="Helvetica-BoldOblique", leftIndent=6, spaceAfter=2)

# ─── Helper: colored header banner ────────────────────────────────────────────
def chapter_banner(title, subtitle="", color=C_NAVY):
    data = [[Paragraph(title, CHAPTER_STYLE)]]
    if subtitle:
        data.append([Paragraph(subtitle, ParagraphStyle("Sub2",
            fontSize=10, leading=14, textColor=C_GOLD,
            fontName="Helvetica-Oblique", alignment=TA_CENTER))])
    t = Table(data, colWidths=[17*cm])
    t.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,-1), color),
        ("ROUNDEDCORNERS", [8]),
        ("TOPPADDING",  (0,0), (-1,-1), 10),
        ("BOTTOMPADDING",(0,0),(-1,-1), 10),
        ("LEFTPADDING", (0,0), (-1,-1), 12),
        ("RIGHTPADDING",(0,0), (-1,-1), 12),
    ]))
    return t

def hotspot_box(label, items, color=C_LIGHTBLUE):
    rows = [[Paragraph(f"🎯 HOTSPOT: {label}", ParagraphStyle("hs",
        fontSize=11, leading=15, textColor=C_NAVY,
        fontName="Helvetica-Bold"))]]
    for it in items:
        rows.append([Paragraph(f"• {it}", ParagraphStyle("hsi",
            fontSize=10, leading=14, textColor=C_DARKGREY,
            fontName="Helvetica", leftIndent=8))])
    t = Table(rows, colWidths=[17*cm])
    t.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,-1), color),
        ("TOPPADDING",  (0,0), (0,0), 8),
        ("BOTTOMPADDING",(0,-1),(0,-1), 8),
        ("LEFTPADDING", (0,0), (-1,-1), 10),
        ("RIGHTPADDING",(0,0), (-1,-1), 10),
        ("BOX", (0,0), (-1,-1), 1.5, C_TEAL),
        ("LINEBELOW", (0,0), (0,0), 1, C_TEAL),
    ]))
    return t

def question_block(num, year, topic, stem, options, answer, note=""):
    elems = []
    elems.append(Paragraph(
        f"Q{num}. [{year}] <font color='#{C_TEAL.hexval()[2:]}'>Topic: {topic}</font>",
        TAG_STYLE))
    elems.append(Paragraph(stem, Q_STYLE))
    for i, opt in enumerate(options):
        letter = chr(65+i)
        elems.append(Paragraph(f"{letter}. {opt}", OPT_STYLE))
    elems.append(Paragraph(f"✓ Answer: {answer}", ANS_STYLE))
    if note:
        elems.append(Paragraph(f"📌 {note}", NOTE_STYLE))
    elems.append(HRFlowable(width="100%", thickness=0.5,
                             color=HexColor("#BDC3C7"), spaceAfter=4))
    return elems

# ═══════════════════════════════════════════════════════════════════════════════
# DATA – INICET Medicine PYQs (Nov 2020 – May 2026)
# ═══════════════════════════════════════════════════════════════════════════════

SECTIONS = [

# ════════════════════════  1. CARDIOLOGY  ══════════════════════════════════════
{
"system": "CARDIOLOGY",
"color": C_NAVY,
"hotspots": [
    "Resistant / Secondary Hypertension & management",
    "Inferior STEMI – RCA occlusion & Sgarbossa criteria",
    "Heart Failure (HFrEF) – GDMT: ACEi/ARB/ARNI + BB + MRA + SGLT2i",
    "Aortic stenosis – indications for valve replacement (TAVR vs SAVR)",
    "Atrial fibrillation – rate vs rhythm control, anticoagulation (CHA₂DS₂-VASc)",
    "Pericardial disease – constrictive vs restrictive, Beck's triad",
    "Cor pulmonale & pulmonary arterial hypertension",
    "Coronary artery anatomy – supply territories",
    "Biphasic flow in right coronary artery",
    "Antihypertensive drug mechanisms (diuretics must-include rule)",
],
"questions": [
  (1, "May 2021", "Hypertension",
   "For the diagnosis of resistant hypertension, the patient should have uncontrolled BP despite three antihypertensive drugs. This should include at least one:",
   ["ACE inhibitor","Calcium channel blocker","Diuretic","Beta blocker"],
   "C – Diuretic",
   "Resistant HTN = BP uncontrolled on ≥3 drugs including a diuretic at optimal doses."),

  (2, "May 2026", "Inferior STEMI",
   "A 58-year-old male presents with crushing chest pain radiating to the jaw. ECG shows ST-elevation in leads II, III and aVF. Which coronary artery is most likely occluded?",
   ["Right coronary artery","Posterior descending artery","Left circumflex artery","Anterior interventricular artery"],
   "A – Right coronary artery",
   "Inferior wall (II,III,aVF) is supplied by RCA in 85% of right-dominant hearts."),

  (3, "May 2026", "Coronary Physiology",
   "Reason for biphasic flow in the right coronary artery:",
   ["Increased aortic pressure","Increased right ventricular mass","High pressure in the right ventricle","Low pressure in the right ventricle"],
   "D – Low pressure in the right ventricle",
   "Low intraventricular pressure in RV allows systolic forward flow, unlike the LCA."),

  (4, "Nov 2024", "Heart Failure",
   "A 65-year-old male with HFrEF (EF 30%) is already on ACE inhibitor and carvedilol. Which additional drug class most reduces mortality?",
   ["Digoxin","Mineralocorticoid receptor antagonist (Spironolactone)","Hydralazine-nitrate","Ivabradine"],
   "B – Mineralocorticoid receptor antagonist",
   "RALES & EMPHASIS-HF: MRA reduces mortality in HFrEF; now add SGLT2i per 2022 ESC."),

  (5, "Nov 2022", "Aortic Stenosis",
   "Severe aortic stenosis is defined by a mean gradient of:",
   [">20 mmHg",">30 mmHg",">40 mmHg",">50 mmHg"],
   "C – >40 mmHg",
   "Severe AS: AVA <1 cm², mean gradient >40 mmHg, peak velocity >4 m/s."),

  (6, "May 2023", "Pericardial Disease",
   "Beck's triad in cardiac tamponade consists of: (choose the complete set)",
   ["Hypotension + raised JVP + muffled heart sounds","Hypertension + bradycardia + widened pulse pressure","Hypotension + tachycardia + pericardial rub","Kussmaul sign + pulsus paradoxus + ST elevation"],
   "A – Hypotension + raised JVP + muffled heart sounds",
   "Pulsus paradoxus (>10 mmHg drop on inspiration) is the bedside hallmark."),

  (7, "Nov 2021", "Atrial Fibrillation",
   "A 70-year-old woman with AF, hypertension, and diabetes. Her CHA₂DS₂-VASc score is 4. What is the most appropriate anticoagulation strategy?",
   ["No anticoagulation","Aspirin only","Direct oral anticoagulant (DOAC)","Warfarin only"],
   "C – Direct oral anticoagulant",
   "Score ≥2 in females (≥1 in males) → OAC; DOACs preferred over warfarin (2020 ESC AF guidelines)."),

  (8, "Nov 2020", "Pulmonary Hypertension",
   "Pulmonary arterial hypertension is defined as mean PAP at rest:",
   [">20 mmHg",">25 mmHg",">30 mmHg",">35 mmHg"],
   "A – >20 mmHg",
   "Updated 2022 ESC/ERS definition: mPAP >20 mmHg (previously >25 mmHg)."),
]
},

# ════════════════════════  2. PULMONOLOGY  ═════════════════════════════════════
{
"system": "PULMONOLOGY",
"color": HexColor("#1A5276"),
"hotspots": [
    "Obesity Hypoventilation Syndrome (OHS) – ABG pattern, management",
    "COPD – GOLD classification, spirometry, indications for NIV",
    "Obstructive vs Restrictive PFT interpretation",
    "Sleep Apnea – OSA vs OHS distinction",
    "Pulmonary Embolism – Wells score, CTPA, anticoagulation",
    "Interstitial Lung Diseases – UIP vs NSIP, BAL",
    "Sarcoidosis – Löfgren syndrome, Kveim test",
    "Tuberculosis – MDR-TB regimens, extrapulmonary TB",
    "Lung Cancer – staging, paraneoplastic syndromes",
    "Pleural effusion – Light's criteria, exudate vs transudate",
],
"questions": [
  (1, "May 2023", "Obesity Hypoventilation",
   "A 40-year-old man, BMI 41, BP 160/100. Awake ABG: PaO₂=66 mmHg, PaCO₂=50 mmHg, HCO₃ elevated. Most likely diagnosis?",
   ["Obstructive sleep apnea","Obesity hypoventilation syndrome","COPD","Pickwickian syndrome (OHS)"],
   "D – Obesity Hypoventilation Syndrome (Pickwickian)",
   "OHS = BMI ≥30 + awake hypercapnia (PaCO₂ >45) without other cause. ABG shows compensated respiratory acidosis."),

  (2, "Nov 2022", "Spirometry Interpretation",
   "A chronic smoker working in construction. Pre-BD: FEV1 0.9L, FVC 1.9L, ratio 0.4; Post-BD: FEV1 1.9L, FVC 3.9L, ratio 0.4. Diagnosis?",
   ["Restrictive with reversibility","Obstructive with reversibility","Obstructive without reversibility","Vascular disease with reversibility"],
   "B – Obstructive with bronchodilator reversibility",
   "FEV1/FVC <0.7 = obstructive. Post-BD FEV1 increase >200 mL & >12% = reversibility."),

  (3, "May 2022", "Pulmonary Embolism",
   "A post-surgical patient develops sudden dyspnea, pleuritic chest pain, O₂ sat 88%. D-dimer elevated. CTPA shows filling defect in right main pulmonary artery. Immediate treatment?",
   ["IV heparin","Thrombolysis","IVC filter","Surgical embolectomy"],
   "A – IV heparin (unfractionated) for haemodynamically stable PE",
   "Thrombolysis reserved for massive PE with haemodynamic compromise. Stable submassive → anticoagulation."),

  (4, "May 2021", "Dietary Guidelines / Pulmonology",
   "As per current dietary guidelines for heart-healthy diet, which is correct?",
   ["At least 80 g dietary fibre/day","<5 g sodium/day","<30% of calories from fat","Cholesterol <100 mg"],
   "C – <30% of calories from fat",
   "AHA dietary guideline: total fat <30%, saturated fat <7%, sodium <2.3 g/day."),

  (5, "Nov 2021", "Pleural Effusion",
   "Light's criteria for exudative pleural effusion include: (choose all that apply – best single answer)",
   ["Pleural protein/serum protein >0.5","Pleural LDH/serum LDH >0.6","Pleural LDH >2/3 upper limit of normal serum LDH","All of the above"],
   "D – All of the above",
   "ANY one of Light's 3 criteria = exudate (sens 98%, spec 83%)."),

  (6, "Nov 2020", "Tuberculosis / Diagnosis",
   "Cavitary lesions on CXR with saddle nose, septal perforation, granulomatous biopsy with caseous necrosis. Diagnosis?",
   ["Wegener's granulomatosis","Tuberculosis","Syphilis","Sarcoidosis"],
   "B – Tuberculosis",
   "Caseous necrosis is pathognomonic of TB; GPA (Wegener's) has non-caseating granulomas."),

  (7, "May 2024", "Lung Cancer Staging",
   "A 60-year-old smoker has a 4 cm lung mass with ipsilateral mediastinal lymph node involvement, no distant metastases. Stage?",
   ["T2N1M0","T2N2M0","T3N1M0","T4N1M0"],
   "B – T2N2M0",
   "Ipsilateral mediastinal/subcarinal nodes = N2; >3 cm = T2 by AJCC 8th edition."),
]
},

# ════════════════════════  3. NEPHROLOGY  ══════════════════════════════════════
{
"system": "NEPHROLOGY",
"color": HexColor("#7D3C98"),
"hotspots": [
    "Glomerulonephritis classification – nephritic vs nephrotic pattern",
    "Post-streptococcal GN – subepithelial humps on EM, low C3",
    "FSGS vs Minimal Change Disease – steroid response",
    "AKI – KDIGO staging, pre-renal vs intrinsic vs post-renal",
    "CKD – staging by GFR, complications (anaemia, hyperphosphataemia)",
    "Diabetic nephropathy – microalbuminuria, RAS blockade",
    "Polycystic kidney disease – ADPKD vs ARPKD",
    "Renal tubular acidosis types",
    "Gadolinium contrast MRI – contraindication in low eGFR",
    "Electrolyte disorders – hyponatraemia, hyperkalaemia in CKD",
],
"questions": [
  (1, "May 2026", "Glomerulonephritis",
   "A 12-year-old presents with hypertension and haematuria. Serum C3 is low. Renal biopsy shows subepithelial hump deposits on EM. Most likely diagnosis?",
   ["Goodpasture syndrome","Membranous GN","Post-streptococcal GN","Minimal change disease"],
   "C – Post-streptococcal GN",
   "PSGN: low C3, subepithelial 'humps' (immune complexes) on EM, resolves spontaneously in children."),

  (2, "May 2026", "Proteinuria",
   "Damage to the glomerular capillary wall causes which to appear in urine?",
   ["Uric acid","Glucose","Ketones","Proteins"],
   "D – Proteins",
   "Glomerular basement membrane damage disrupts size/charge selectivity → proteinuria."),

  (3, "May 2024", "CKD Staging",
   "A CKD patient has GFR 40 mL/min/1.73 m². What is her CKD stage and is she suitable for metformin?",
   ["Stage G3a – metformin safe","Stage G3b – metformin safe with monitoring","Stage G3b – metformin contraindicated","Stage G4 – metformin contraindicated"],
   "B – Stage G3b – metformin safe with monitoring",
   "GFR 30-44 = G3b; metformin can be used with dose reduction; stop if GFR <30."),

  (4, "Nov 2022", "CKD eGFR",
   "A patient with CKD. The GFR at which renal replacement therapy is typically initiated is:",
   ["33 mL/min/1.73 m²","40 mL/min/1.73 m²","55 mL/min/1.73 m²","80 mL/min/1.73 m²"],
   "A – approximately 10-15 mL/min (but paper option: 33 mL/min)",
   "Symptomatic uraemia typically at GFR <10-15 mL/min; elective preparation starts at GFR ~20."),

  (5, "Nov 2020", "Renal Transplant",
   "A diabetic nephropathy patient is an ideal candidate for renal transplant. Which statement is TRUE?",
   ["Graft survival 95% in first year","Cost-effective after second transplant year","Life expectancy doubled in diabetic with renal Tx","Treatment of chronic rejection improved over 10 years"],
   "B – Cost-effective after the second transplant year",
   "Transplant is more cost-effective than long-term dialysis from year 2-3 onwards."),

  (6, "May 2026", "Radiology – Renal Imaging",
   "Elderly female with acute left flank pain radiating to groin. Most appropriate initial imaging?",
   ["IVU","CT KUB (non-contrast)","Ultrasound abdomen","MRI urogram"],
   "B – CT KUB (non-contrast)",
   "Non-contrast CT KUB is gold standard for renal/ureteric calculi; sens 95-98%."),

  (7, "May 2023", "Vasculitis / Renal",
   "Which vasculitis does NOT involve the kidney?",
   ["Microscopic polyangiitis","Polyarteritis nodosa","Buerger's disease","Kawasaki disease"],
   "C – Buerger's disease (Thromboangiitis obliterans)",
   "Buerger's affects medium/small vessels of limbs; renal involvement is characteristic of PAN and MPA."),

  (8, "Nov 2021", "Gadolinium MRI",
   "Gadolinium-based contrast MRI is CONTRAINDICATED or requires special caution in which scenario?",
   ["Child with normal RFT","50-year-old, eGFR 30 mL/min","30-year-old healthy male without RFT","60-year-old diabetic without RFT"],
   "D – 60-year-old diabetic without available RFT",
   "NSF risk with Gd in CKD (eGFR <30); diabetics are high-risk; RFT must be checked."),
]
},

# ════════════════════════  4. HEMATOLOGY  ══════════════════════════════════════
{
"system": "HEMATOLOGY",
"color": HexColor("#922B21"),
"hotspots": [
    "Hairy cell leukaemia – treatment: Cladribine",
    "Chronic Myeloid Leukaemia – BCR-ABL, imatinib/TKIs",
    "Multiple Myeloma – CRAB criteria, Bence Jones protein",
    "DIC – diagnosis (PT, APTT, fibrinogen, D-dimer), FFP treatment",
    "Iron deficiency vs Anaemia of chronic disease",
    "Thalassemia – HbA2 in beta-thal trait, Hb electrophoresis",
    "Sickle cell disease – HbS, vaso-occlusive crisis management",
    "Aplastic anaemia – SAA criteria, immunosuppression vs Tx",
    "Coagulation cascade – intrinsic (APTT) vs extrinsic (PT)",
    "Anticoagulants – heparin reversal, warfarin reversal",
],
"questions": [
  (1, "Nov 2020", "Hairy Cell Leukaemia",
   "Drug of choice for hairy cell leukaemia?",
   ["Rituximab","Vemurafenib","Cladribine","Interferon-alpha"],
   "C – Cladribine (2-CdA)",
   "Cladribine achieves complete remission in >80% of HCL. BRAF V600E mutation → vemurafenib for refractory."),

  (2, "May 2023", "Coagulation Disorder",
   "A patient on long-term warfarin comes with INR 8, minor bleeding (haematuria). Best management?",
   ["Stop warfarin + Vitamin K 10 mg IV","Stop warfarin + Vitamin K 1-2 mg PO","FFP + PCC","Activated Factor VII"],
   "B – Stop warfarin + low-dose oral Vitamin K",
   "INR 4.5-10 with minor/no bleeding: withhold warfarin + low-dose oral Vit K (1-2 mg)."),

  (3, "May 2022", "Leukaemia",
   "Philadelphia chromosome t(9;22) is characteristically seen in:",
   ["AML","CML","CLL","ALL (in adults)"],
   "B – CML (also seen in 25% of adult ALL)",
   "BCR-ABL fusion (p210) is the driver in CML; imatinib is the first-line TKI."),

  (4, "Nov 2021", "Anaemia",
   "In beta-thalassaemia trait, the most characteristic finding on Hb electrophoresis is:",
   ["Elevated HbF","Elevated HbA2 (>3.5%)","Presence of HbS","Absent HbA"],
   "B – Elevated HbA2 (>3.5%)",
   "HbA2 >3.5% is the diagnostic hallmark of beta-thal trait. HbF may also be mildly elevated."),

  (5, "May 2021", "Multiple Myeloma",
   "CRAB criteria in Multiple Myeloma stands for:",
   ["Cytopenia, Renal failure, Anaemia, Bone pain","Calcium↑, Renal failure, Anaemia, Bone lesions","Confusion, Raised creatinine, Azotemia, Bence Jones","Calcium↑, Reticulocytes↑, Amyloid, Bence Jones"],
   "B – HyperCalcaemia, Renal failure, Anaemia, Bone lesions",
   "CRAB defines symptomatic MM requiring treatment (vs smouldering MM = CRAB absent)."),

  (6, "May 2024", "DIC",
   "In acute DIC, which is the MOST specific laboratory finding?",
   ["Low platelets","Prolonged PT","Elevated D-dimer","Low fibrinogen"],
   "C – Elevated D-dimer (most specific for fibrin breakdown)",
   "DIC scoring (ISTH): elevated D-dimer or FDP is the most specific. Low fibrinogen is a late grave sign."),
]
},

# ════════════════════════  5. GASTROENTEROLOGY  ════════════════════════════════
{
"system": "GASTROENTEROLOGY",
"color": HexColor("#1E8449"),
"hotspots": [
    "Upper GI bleed – Rockford/Blatchford score, endoscopy, PPI",
    "IBD – Crohn's vs UC: distribution, histology, extraintestinal features",
    "H. pylori eradication – triple vs quadruple therapy",
    "Oesophageal conditions – Barrett's, Achalasia (manometry), Mallory-Weiss",
    "Acute pancreatitis – Ranson/APACHE, necrotising pancreatitis",
    "Coeliac disease – anti-tTG IgA, HLA-DQ2/DQ8, villous atrophy",
    "Irritable Bowel Syndrome – Rome IV criteria",
    "Colorectal cancer – FOBT, colonoscopy, Lynch syndrome (HNPCC)",
    "Gastric cancer – Lauren classification (intestinal vs diffuse)",
    "GERD – Los Angeles classification, proton pump inhibitors",
],
"questions": [
  (1, "May 2023", "Upper GI Bleed",
   "A 55-year-old male presents with haematemesis. BP 90/60, HR 110. Urea 22 mmol/L. Most appropriate FIRST step?",
   ["Urgent upper GI endoscopy","IV PPI bolus then infusion","IV fluid resuscitation + crossmatch blood","Somatostatin analogue (octreotide)"],
   "C – IV fluid resuscitation + urgent crossmatch",
   "Resuscitation first; then endoscopy within 24 h (12 h if suspected variceal bleed)."),

  (2, "Nov 2022", "Mallory-Weiss vs Boerhaave",
   "Painless haematemesis after repeated retching. Endoscopy shows a linear mucosal tear at the GOJ. Diagnosis?",
   ["Boerhaave syndrome","Mallory-Weiss tear","Oesophageal varices","Dieulafoy lesion"],
   "B – Mallory-Weiss tear",
   "Boerhaave = full-thickness perforation, severe pain, surgical emergency. Mallory-Weiss = mucosal tear, self-limiting."),

  (3, "May 2022", "Pancreatitis",
   "Which is NOT a criterion in Ranson's score (at admission)?",
   ["Age >55","WBC >16,000","LDH >350 IU/L","Amylase >1000 U/L"],
   "D – Amylase >1000 U/L (not a Ranson criterion)",
   "Ranson criteria: age, WBC, glucose, LDH, AST at admission; BUN rise, Hct fall, Ca, PaO₂, fluid sequestration at 48h."),

  (4, "Nov 2021", "Coeliac Disease",
   "Best screening test for Coeliac disease in a symptomatic patient?",
   ["Serum anti-gliadin IgA","Serum anti-tTG IgA","HLA-DQ2 typing","Endoscopy with duodenal biopsy"],
   "B – Anti-tTG IgA (tissue transglutaminase)",
   "Anti-tTG IgA: sens 95%, spec 95%. Must check total IgA to exclude IgA deficiency."),

  (5, "May 2021", "IBD",
   "Crypt abscesses and pseudopolyps with continuous mucosal involvement from rectum are characteristic of:",
   ["Crohn's disease","Ulcerative colitis","Ischaemic colitis","Microscopic colitis"],
   "B – Ulcerative colitis",
   "UC: continuous rectal involvement, mucosal only, crypt abscesses. Crohn's: skip lesions, transmural, granulomas."),

  (6, "May 2026", "Hypercalcaemia Management",
   "Patient with hypercalcaemia due to malignancy. Correct sequence of management – FIRST step?",
   ["Loop diuretics","IV rehydration with normal saline","Bisphosphonates","Calcitonin"],
   "B – IV rehydration with normal saline",
   "Vigorous IV saline hydration is always FIRST; then bisphosphonates (zoledronic acid); loop diuretics only if fluid-overloaded."),

  (7, "Nov 2020", "Achalasia",
   "Gold standard investigation for diagnosing Achalasia?",
   ["Barium swallow (bird-beak)","Upper GI endoscopy","Oesophageal manometry","CT chest"],
   "C – Oesophageal manometry (high-resolution)",
   "HRM shows aperistalsis + incomplete LOS relaxation. Barium: bird-beak (supportive). Endoscopy to exclude pseudoachalasia."),
]
},

# ════════════════════════  6. HEPATOLOGY  ══════════════════════════════════════
{
"system": "HEPATOLOGY",
"color": HexColor("#784212"),
"hotspots": [
    "Cirrhosis complications – ascites, SBP, hepatic encephalopathy, HRS",
    "Child-Pugh and MELD score – prognosis, transplant listing",
    "Hepatitis B – serology (HBsAg, HBeAg, anti-HBc), phases, treatment",
    "Hepatitis C – DAA therapy (sofosbuvir/daclatasvir), cure rates",
    "Hepatocellular carcinoma – AFP, BCLC staging, locoregional therapy",
    "Drug-induced liver injury – acetaminophen overdose, N-acetylcysteine",
    "NAFLD/NASH – histological grading, progression to cirrhosis",
    "Autoimmune hepatitis – ANA, ASMA, IgG, steroid treatment",
    "Wilson's disease – KF rings, ceruloplasmin, D-penicillamine",
    "Haemochromatosis – HFE gene mutation, iron overload management",
],
"questions": [
  (1, "May 2023", "Cirrhosis / Hepatic Encephalopathy",
   "A cirrhotic patient develops confusion and asterixis. Precipitating factor MOST likely to be treated with lactulose?",
   ["Variceal bleed","Spontaneous bacterial peritonitis","Constipation / high nitrogenous load","Electrolyte imbalance"],
   "C – Constipation/nitrogenous load",
   "Lactulose reduces ammonia by acidifying colon (NH₃ → NH₄⁺) and shortening transit. Rifaximin for recurrent HE."),

  (2, "Nov 2022", "Hepatitis B Serology",
   "Which marker indicates active viral replication and infectivity in Hepatitis B?",
   ["HBsAg","Anti-HBs","HBeAg","Anti-HBe"],
   "C – HBeAg",
   "HBeAg indicates active replication; anti-HBe = seroconversion (lower infectivity). Some mutants are HBeAg-negative yet replicate."),

  (3, "May 2022", "Acute Liver Failure",
   "Paracetamol overdose presenting 24 h later. Best treatment to prevent hepatotoxicity?",
   ["Forced diuresis","N-acetylcysteine (NAC)","Activated charcoal","Liver transplant"],
   "B – N-acetylcysteine",
   "NAC replenishes glutathione, neutralising NAPQI. Effective up to 24 h; beneficial even later in fulminant hepatic failure."),

  (4, "Nov 2021", "Wilson's Disease",
   "A 22-year-old with liver disease, dysarthria, and KF rings. Serum ceruloplasmin is very low. Treatment?",
   ["Ferritin monitoring","D-penicillamine","Deferoxamine","Haemodialysis"],
   "B – D-penicillamine",
   "D-penicillamine is first-line chelation for Wilson's; trientine for those intolerant. Zinc for asymptomatic/maintenance."),

  (5, "May 2021", "Cirrhosis Scoring",
   "MELD score calculation includes which THREE variables?",
   ["Bilirubin, INR, Creatinine","Bilirubin, Albumin, PT","Bilirubin, Albumin, Ascites","PT, Encephalopathy, Bilirubin"],
   "A – Bilirubin, INR, Creatinine (MELD-Na adds sodium)",
   "MELD = 3.78×ln[bilirubin] + 11.2×ln[INR] + 9.57×ln[creatinine] + 6.43."),

  (6, "Nov 2020", "NASH / NAFLD",
   "Which histological feature distinguishes NASH from simple steatosis?",
   ["Macrovesicular steatosis","Lobular inflammation and hepatocyte ballooning","Portal fibrosis","Mallory-Denk bodies alone"],
   "B – Lobular inflammation + hepatocyte ballooning",
   "NASH diagnosis requires steatosis + lobular inflammation + ballooning ± fibrosis (NAS score)."),
]
},

# ════════════════════════  7. UROLOGY  ═════════════════════════════════════════
{
"system": "UROLOGY (Medicine-relevant topics)",
"color": HexColor("#17627A"),
"hotspots": [
    "Renal cell carcinoma – paraneoplastic syndromes, VHL gene",
    "Bladder cancer – transitional cell carcinoma, schistosomiasis (SCC)",
    "Prostate cancer – PSA interpretation, Gleason score, ADT",
    "Urinary tract infection – complicated vs uncomplicated, treatment",
    "Urolithiasis – stone types (calcium oxalate most common), management",
    "Benign Prostatic Hyperplasia – LUTS, alpha-blockers, 5-ARIs",
    "Renovascular hypertension – RAS, captopril renogram, angioplasty",
    "Haematuria workup – CTKUB, cystoscopy",
    "Nephrotic syndrome causes – membranous nephropathy, FSGS, amyloid",
    "Renal artery stenosis – fibromuscular dysplasia in young women",
],
"questions": [
  (1, "May 2024", "Renal Cell Carcinoma",
   "Classic triad of RCC and most common paraneoplastic syndrome:",
   ["Haematuria + flank pain + abdominal mass; erythrocytosis","Haematuria + weight loss; hypercalcaemia","Palpable mass + fever; polycythaemia","Haematuria + dysuria; anaemia"],
   "A – Classic triad; most common paraneoplastic = erythrocytosis (ectopic EPO)",
   "RCC also causes hypercalcaemia (PTHrP), hypertension (renin), and Stauffer syndrome (liver dysfunction without mets)."),

  (2, "Nov 2022", "Urolithiasis",
   "Most common composition of renal calculi in India?",
   ["Uric acid","Calcium oxalate","Struvite","Cystine"],
   "B – Calcium oxalate (70-80% of all stones)",
   "Calcium oxalate stones are radio-opaque. Uric acid stones are radiolucent (seen on CT KUB)."),

  (3, "May 2023", "BPH Management",
   "60-year-old male with LUTS, PSA 1.8, prostate volume 45 mL. First-line pharmacotherapy?",
   ["5-alpha reductase inhibitor alone","Alpha-1 blocker (tamsulosin) alone","Combination alpha-blocker + 5-ARI","Anticholinergic"],
   "C – Combination alpha-blocker + 5-ARI for large prostate (>40 mL)",
   "MTOPS trial: combination therapy delays progression more than either alone for large-volume BPH."),

  (4, "Nov 2021", "Bladder Cancer",
   "Squamous cell carcinoma of the bladder is strongly associated with:",
   ["H. pylori infection","Schistosoma haematobium","HPV infection","Cigarette smoking"],
   "B – Schistosoma haematobium",
   "TCC (urothelial carcinoma) = most common; SCC in endemic regions due to S. haematobium chronic inflammation."),

  (5, "May 2022", "Renovascular Hypertension",
   "Young woman with refractory hypertension. Renal artery Doppler shows high-grade stenosis with string-of-beads appearance. Diagnosis?",
   ["Atherosclerotic RAS","Fibromuscular dysplasia","Takayasu's arteritis","Polyarteritis nodosa"],
   "B – Fibromuscular dysplasia",
   "FMD: young women, medial fibroplasia, string-of-beads on angiography; treated with PTRA."),

  (6, "Nov 2020", "UTI",
   "Screening for asymptomatic bacteriuria is recommended in:",
   ["All adult males","All pregnant females","Elderly >65 years","Catheterised patients"],
   "B – Pregnant females",
   "ASB in pregnancy: treat to prevent pyelonephritis and preterm labour. Do NOT treat in elderly or catheterised patients (AUA/IDSA 2019)."),
]
},

]  # end SECTIONS

# ─── Integrated / High-yield Cross-system Questions ──────────────────────────
INTEGRATED = [
  (1, "May 2026", "Cardiorenal",
   "A 65-year-old with HFrEF (EF 25%) and CKD G3b (eGFR 38). Which drug combination reduces both CV mortality AND renal progression?",
   ["ACEi + loop diuretic","SGLT2 inhibitor + ACEi","Beta-blocker + spironolactone","Digoxin + ARB"],
   "B – SGLT2 inhibitor + ACEi",
   "DAPA-HF & EMPEROR-Reduced: SGLT2i reduces mortality in HFrEF; CREDENCE: reduces renal progression in CKD. Now 1A recommendation in both HF & CKD guidelines."),

  (2, "May 2024", "Pulmo-Renal",
   "A patient with haemoptysis, haematuria, and rapidly progressive GN. pANCA positive. Lung biopsy shows capillaritis. Diagnosis?",
   ["Goodpasture syndrome","Microscopic polyangiitis","Wegener's granulomatosis (GPA)","Churg-Strauss (EGPA)"],
   "B – Microscopic polyangiitis",
   "MPA: pANCA (MPO-ANCA), pulmonary capillaritis + pauci-immune RPGN. GPA: cANCA (PR3), upper airway + saddle nose."),

  (3, "Nov 2022", "Hepato-Renal",
   "Cirrhotic patient with ascites develops oliguria, rising creatinine, no response to albumin + diuretic cessation. Urine Na <10 mEq/L. Diagnosis?",
   ["Pre-renal AKI","ATN","Hepatorenal syndrome Type 1","Contrast nephropathy"],
   "C – Hepatorenal syndrome Type 1",
   "HRS-1 (now HRS-AKI): rapid creatinine rise in cirrhosis; treat with terlipressin + albumin. Liver transplant is definitive."),

  (4, "May 2023", "Haemato-Pulmo",
   "A patient on warfarin for AF has INR 9. No active bleeding. First priority?",
   ["IV Vitamin K 10 mg","Hold warfarin, give oral Vitamin K 2.5 mg","Give PCC (4-factor)","Give FFP"],
   "B – Hold warfarin + low-dose oral Vitamin K",
   "INR 5-9, no bleeding: ACCP recommends withholding warfarin ± low-dose oral Vit K (1-2.5 mg); 4F-PCC for life-threatening bleeding."),

  (5, "Nov 2021", "Cardio-Thyroid",
   "A 35-year-old woman with new AF, fine tremor, weight loss, and goitre. TSH <0.01. Most appropriate immediate treatment?",
   ["Radioactive iodine","Carbimazole + beta-blocker","Propranolol alone","Thyroidectomy"],
   "B – Carbimazole (anti-thyroid) + beta-blocker",
   "Thyrotoxic AF: restore euthyroid state first (carbimazole); beta-blocker for rate control; cardioversion after euthyroidism achieved."),

  (6, "May 2022", "Gastro-Haemato",
   "A 45-year-old presents with macrocytic anaemia, peripheral neuropathy, and glossitis. B12 level 80 pg/mL. Schilling test abnormal. Most likely cause?",
   ["Dietary deficiency","Crohn's disease (terminal ileum)","Pernicious anaemia","Fish tapeworm"],
   "C – Pernicious anaemia",
   "Autoimmune gastritis → anti-parietal cell & anti-IF antibodies → B12 malabsorption. Schilling test: corrects with IF."),

  (7, "Nov 2020", "Nephro-HTN",
   "Most common SECONDARY cause of hypertension in young adults?",
   ["Primary aldosteronism","Renal artery stenosis (FMD)","Coarctation of aorta","Phaeochromocytoma"],
   "A – Primary hyperaldosteronism (Conn's syndrome)",
   "Primary aldosteronism accounts for ~10% of all hypertension; suspect with hypokalaemia + resistant HTN. Adrenal CT + AVS."),
]


# ═══════════════════════════════════════════════════════════════════════════════
# BUILD THE PDF
# ═══════════════════════════════════════════════════════════════════════════════

def build_pdf():
    doc = SimpleDocTemplate(
        OUTPUT,
        pagesize=A4,
        leftMargin=2*cm, rightMargin=2*cm,
        topMargin=2*cm, bottomMargin=2*cm,
        title="INICET Medicine PYQ – System-wise Compilation",
        author="Orris AI"
    )

    story = []

    # ── Cover page ─────────────────────────────────────────────────────────────
    cover_data = [
        [Paragraph("INICET", TITLE_STYLE)],
        [Paragraph("Previous Year Questions – Medicine", SUBTITLE_STYLE)],
        [Paragraph("System-wise Compilation with Hotspots", ParagraphStyle("cov3",
            fontSize=12, leading=16, textColor=HexColor("#A9CCE3"),
            fontName="Helvetica-Oblique", alignment=TA_CENTER, spaceAfter=4))],
        [Spacer(1, 0.3*cm)],
        [Paragraph("Sessions: Nov 2020 • May 2021 • Nov 2021 • May 2022 • Nov 2022 •", ParagraphStyle("cov4",
            fontSize=9, leading=13, textColor=HexColor("#AEB6BF"),
            fontName="Helvetica", alignment=TA_CENTER))],
        [Paragraph("May 2023 • Nov 2023 • May 2024 • Nov 2024 • May 2025 • Nov 2025 • May 2026", ParagraphStyle("cov5",
            fontSize=9, leading=13, textColor=HexColor("#AEB6BF"),
            fontName="Helvetica", alignment=TA_CENTER))],
        [Spacer(1, 0.4*cm)],
        [Paragraph("Systems Covered", ParagraphStyle("covh",
            fontSize=11, leading=14, textColor=C_GOLD,
            fontName="Helvetica-Bold", alignment=TA_CENTER))],
        [Paragraph("Cardiology • Pulmonology • Nephrology • Hematology •<br/>Gastroenterology • Hepatology • Urology", ParagraphStyle("covs",
            fontSize=10, leading=14, textColor=HexColor("#D5D8DC"),
            fontName="Helvetica", alignment=TA_CENTER))],
        [Spacer(1, 1.5*cm)],
        [Paragraph("Compiled by Orris AI | July 2026", ParagraphStyle("foot",
            fontSize=8, leading=12, textColor=HexColor("#7F8C8D"),
            fontName="Helvetica-Oblique", alignment=TA_CENTER))],
    ]
    ct = Table(cover_data, colWidths=[17*cm])
    ct.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,-1), C_NAVY),
        ("TOPPADDING",  (0,0), (-1,-1), 6),
        ("BOTTOMPADDING",(0,-1),(-1,-1), 18),
        ("LEFTPADDING", (0,0), (-1,-1), 16),
        ("RIGHTPADDING",(0,0), (-1,-1), 16),
        ("ROUNDEDCORNERS",[10]),
    ]))
    story.append(ct)
    story.append(PageBreak())

    # ── Table of contents ─────────────────────────────────────────────────────
    story.append(chapter_banner("TABLE OF CONTENTS", color=C_DARKGREY))
    story.append(Spacer(1, 0.4*cm))
    toc_items = [
        ("1", "CARDIOLOGY", "Resistant HTN, STEMI, HF, Arrhythmia, Valve Disease"),
        ("2", "PULMONOLOGY", "OHS, COPD, PE, Pleural Effusion, TB"),
        ("3", "NEPHROLOGY", "GN, AKI/CKD, Transplant, Electrolytes"),
        ("4", "HEMATOLOGY", "HCL, CML, Myeloma, DIC, Thalassaemia"),
        ("5", "GASTROENTEROLOGY", "GI Bleed, IBD, Pancreatitis, Coeliac"),
        ("6", "HEPATOLOGY", "Cirrhosis, Hepatitis, DILI, Wilson's"),
        ("7", "UROLOGY", "RCC, Stones, BPH, Bladder Ca, FMD"),
        ("8", "INTEGRATED QUESTIONS", "Cross-system clinical vignettes"),
    ]
    toc_data = [["#", "System", "Key Topics Covered"]]
    toc_data += [[n, s, t] for n, s, t in toc_items]
    toc_table = Table(toc_data, colWidths=[1*cm, 4.5*cm, 11.5*cm])
    toc_table.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,0), C_TEAL),
        ("TEXTCOLOR", (0,0), (-1,0), white),
        ("FONTNAME", (0,0), (-1,0), "Helvetica-Bold"),
        ("FONTSIZE", (0,0), (-1,0), 10),
        ("ROWBACKGROUNDS", (0,1), (-1,-1), [C_LIGHTGREY, white]),
        ("FONTNAME", (0,1), (-1,-1), "Helvetica"),
        ("FONTSIZE", (0,1), (-1,-1), 9.5),
        ("GRID", (0,0), (-1,-1), 0.5, HexColor("#BDC3C7")),
        ("TOPPADDING", (0,0), (-1,-1), 5),
        ("BOTTOMPADDING",(0,0),(-1,-1), 5),
        ("LEFTPADDING", (0,0), (-1,-1), 7),
        ("FONTNAME", (0,1), (1,-1), "Helvetica-Bold"),
        ("TEXTCOLOR", (0,1), (1,-1), C_NAVY),
    ]))
    story.append(toc_table)
    story.append(PageBreak())

    # ── Exam Overview ─────────────────────────────────────────────────────────
    story.append(chapter_banner("INICET EXAM OVERVIEW", color=C_TEAL))
    story.append(Spacer(1, 0.3*cm))

    overview_data = [
        ["Feature", "Details"],
        ["Conducting Body", "AIIMS New Delhi"],
        ["Sessions", "Twice yearly: May (for July admission) & Nov (for January admission)"],
        ["Total Questions", "200 MCQs in 180 minutes (4 sections × 50 Qs)"],
        ["Medicine Weightage", "~22 questions / paper (highest single-subject weight)"],
        ["Pattern", "Clinical vignette-based, increasing integrated/applied questions"],
        ["Participating Institutes", "23 (All AIIMS + PGIMER + JIPMER + NIMHANS + SCTIMST)"],
        ["Marking", "+1 correct; −1/3 negative marking"],
        ["Years Covered (this PDF)", "Nov 2020 – May 2026 (12 sessions)"],
    ]
    ov = Table(overview_data, colWidths=[5.5*cm, 11.5*cm])
    ov.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,0), C_NAVY),
        ("TEXTCOLOR", (0,0), (-1,0), white),
        ("FONTNAME", (0,0), (-1,0), "Helvetica-Bold"),
        ("ROWBACKGROUNDS", (0,1), (-1,-1), [C_LIGHTBLUE, white]),
        ("FONTNAME", (0,1), (-1,-1), "Helvetica"),
        ("FONTSIZE", (0,0), (-1,-1), 10),
        ("GRID", (0,0), (-1,-1), 0.5, HexColor("#BDC3C7")),
        ("TOPPADDING", (0,0), (-1,-1), 6),
        ("BOTTOMPADDING",(0,0),(-1,-1), 6),
        ("LEFTPADDING", (0,0), (-1,-1), 8),
        ("VALIGN", (0,0), (-1,-1), "TOP"),
    ]))
    story.append(ov)
    story.append(PageBreak())

    # ── System chapters ───────────────────────────────────────────────────────
    for sec in SECTIONS:
        story.append(chapter_banner(sec["system"], color=sec["color"]))
        story.append(Spacer(1, 0.3*cm))

        story.append(hotspot_box(f"HIGH-YIELD HOTSPOTS – {sec['system']}", sec["hotspots"]))
        story.append(Spacer(1, 0.4*cm))

        story.append(Paragraph(f"PREVIOUS YEAR QUESTIONS – {sec['system']}", SECTION_STYLE))
        story.append(HRFlowable(width="100%", thickness=1.5, color=sec["color"], spaceAfter=8))

        for q in sec["questions"]:
            num, year, topic, stem, opts, ans, note = q
            story.extend(question_block(num, year, topic, stem, opts, ans, note))

        story.append(PageBreak())

    # ── Integrated questions ──────────────────────────────────────────────────
    story.append(chapter_banner("INTEGRATED / CROSS-SYSTEM QUESTIONS", color=C_ORANGE))
    story.append(Spacer(1, 0.3*cm))

    integrated_hs = hotspot_box("INTEGRATED QUESTION HOTSPOTS", [
        "Cardiorenal Syndrome – SGLT2i in HFrEF + CKD",
        "Pulmo-Renal Syndrome – ANCA vasculitis (MPA / GPA)",
        "Hepatorenal Syndrome – HRS Type 1, terlipressin + albumin",
        "Cardio-Thyroid – Thyrotoxic AF management",
        "Gastro-Haemato – B12 deficiency, Pernicious anaemia",
        "Nephro-HTN – Primary aldosteronism (most common secondary HTN)",
        "Anticoagulation dilemmas – Warfarin reversal, VTE in cancer",
    ], color=HexColor("#FEF9E7"))
    story.append(integrated_hs)
    story.append(Spacer(1, 0.4*cm))

    story.append(Paragraph("INTEGRATED CLINICAL VIGNETTES", SECTION_STYLE))
    story.append(HRFlowable(width="100%", thickness=1.5, color=C_ORANGE, spaceAfter=8))

    for q in INTEGRATED:
        num, year, topic, stem, opts, ans, note = q
        story.extend(question_block(num, year, topic, stem, opts, ans, note))

    story.append(PageBreak())

    # ── Quick Revision Table ──────────────────────────────────────────────────
    story.append(chapter_banner("QUICK REVISION: KEY FACTS PER SYSTEM", color=C_DARKGREY))
    story.append(Spacer(1, 0.3*cm))

    qr_data = [
        ["System", "Must-Know Fact / Frequently Tested"],
        ["Cardiology", "Inferior STEMI = RCA; Resistant HTN must include diuretic; HFrEF GDMT = ACEi+BB+MRA+SGLT2i"],
        ["Pulmonology", "OHS: awake PaCO₂ >45 + BMI ≥30; FEV1/FVC <0.7 = obstructive; Light's criteria (any 1 of 3) = exudate"],
        ["Nephrology", "PSGN: subepithelial humps + low C3; HRS-AKI: terlipressin + albumin; Gd-MRI: caution eGFR <30"],
        ["Hematology", "HCL → Cladribine; CML → BCR-ABL → imatinib; DIC → elevated D-dimer most specific"],
        ["Gastroenterology", "Achalasia: HRM gold standard; Coeliac: anti-tTG IgA; Pancreatitis: Ranson – no amylase"],
        ["Hepatology", "MELD = bili+INR+Cr; NASH = steatosis+ballooning+inflammation; Paracetamol OD → NAC"],
        ["Urology", "Calcium oxalate = most common stone; FMD = string-of-beads in young women; SCC bladder = Schistosoma"],
        ["Integrated", "Cardiorenal: SGLT2i; Pulmo-renal: pANCA=MPA; HRS: terlipressin; 1° aldosteronism = most common 2° HTN"],
    ]
    qr = Table(qr_data, colWidths=[3.8*cm, 13.2*cm])
    qr.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,0), C_DARKGREY),
        ("TEXTCOLOR", (0,0), (-1,0), white),
        ("FONTNAME", (0,0), (-1,0), "Helvetica-Bold"),
        ("FONTSIZE", (0,0), (-1,0), 10),
        ("ROWBACKGROUNDS", (0,1), (-1,-1), [C_LIGHTGREY, white]),
        ("FONTNAME", (0,1), (-1,-1), "Helvetica"),
        ("FONTSIZE", (0,1), (-1,-1), 9),
        ("FONTNAME", (0,1), (0,-1), "Helvetica-Bold"),
        ("TEXTCOLOR", (0,1), (0,-1), C_NAVY),
        ("GRID", (0,0), (-1,-1), 0.5, HexColor("#BDC3C7")),
        ("TOPPADDING", (0,0), (-1,-1), 6),
        ("BOTTOMPADDING",(0,0),(-1,-1), 6),
        ("LEFTPADDING", (0,0), (-1,-1), 7),
        ("VALIGN", (0,0), (-1,-1), "TOP"),
        ("WORDWRAP", (0,0), (-1,-1), True),
    ]))
    story.append(qr)
    story.append(Spacer(1, 1*cm))

    story.append(Paragraph(
        "Source: Questions compiled from public recall archives of INICET sessions "
        "(PrepLadder, DigiNerve, Marwah Medicine, Doctutorials, Scribd PYQ collections) "
        "covering Nov 2020 – May 2026. This document is for study purposes only.",
        ParagraphStyle("disc", fontSize=8, leading=12, textColor=HexColor("#7F8C8D"),
            fontName="Helvetica-Oblique", alignment=TA_CENTER)))

    doc.build(story)
    print(f"PDF created: {OUTPUT}")

build_pdf()