Here is the complete breakdown of most important Communicable Diseases for BHMS PSM university exam, ranked by frequency of appearance across papers:
Communicable Diseases - BHMS PSM Exam (Most Important)
🥇 TIER 1 - Most Repeated (Almost Every Year)
1. TUBERCULOSIS (TB)
Most asked topic - comes as long essay or short note
| Point | Detail |
|---|
| Agent | Mycobacterium tuberculosis |
| Source | Sputum-positive patient (droplet nuclei) |
| Transmission | Airborne - droplet nuclei (most common) |
| Pathology | Primary complex in lung, Ghon focus |
| Tuberculin test | Mantoux test - >10mm = positive |
| Diagnosis | Sputum AFB, CBNAAT/Gene Xpert, X-ray |
| Treatment | DOTS - Cat I: 2HRZE + 4HR |
| Prevention | BCG vaccine at birth, RNTCP/NSP |
| Programme | National Tuberculosis Elimination Programme (NTEP) - target elimination by 2025 |
Probable questions: Epidemiology of TB / Tuberculin test / BCG vaccine / DOTS / RNTCP
2. MALARIA
Highest yield vector-borne disease
| Point | Detail |
|---|
| Agent | P. vivax (benign tertian), P. falciparum (malignant tertian - most dangerous) |
| Vector | Female Anopheles mosquito (bites at night) |
| Transmission | Bite of infected female Anopheles |
| Clinical | Fever with chills & rigors, splenomegaly |
| Diagnosis | Peripheral blood smear (gold standard), RDT, PCR |
| Treatment | Chloroquine (P. vivax), ACT - Artemisinin (P. falciparum) |
| Prevention | ITN (Insecticide Treated Nets), IRS (Indoor Residual Spraying), larvicides |
| Programme | National Vector Borne Disease Control Programme (NVBDCP) |
Probable questions: Epidemiology of malaria & its control / Vector control methods / NVBDCP
3. POLIO
Eradication success story - always asked
| Point | Detail |
|---|
| Agent | Poliovirus (enterovirus) - Type 1, 2, 3 |
| Transmission | Feco-oral route (most common), respiratory |
| Reservoir | Humans only |
| Clinical | 90% silent; <1% flaccid paralysis |
| Diagnosis | Stool culture (gold standard), serology |
| Vaccine | OPV (oral - Sabin) + IPV (injectable - Salk) |
| India status | Polio-free since January 2011, certified 2014 |
| Programme | Pulse Polio Immunization - "Do Boond Zindagi Ki" |
Probable questions: Epidemiology of polio & prevention / Pulse Polio Programme
4. DIPHTHERIA
Repeatedly asked as long essay in BHMS (Rajiv Gandhi University papers)
| Point | Detail |
|---|
| Agent | Corynebacterium diphtheriae (Klebs-Loeffler bacillus) |
| Transmission | Droplet infection, direct contact |
| Pathology | Pseudomembrane in throat, exotoxin causes cardiac & neural damage |
| Diagnosis | Schick test (for susceptibility), culture, Albert stain |
| Treatment | Diphtheria Antitoxin (DAT) + Penicillin/Erythromycin |
| Prevention | DPT vaccine (3 doses), DT booster |
| Schick test | +ve = susceptible; -ve = immune |
Probable questions: Detail Diphtheria / Schick test / DPT vaccine
🥈 TIER 2 - Frequently Asked (Short Notes / Short Essays)
5. TYPHOID (Enteric Fever)
| Key Points | Detail |
|---|
| Agent | Salmonella typhi |
| Route | Feco-oral (5 F's - Flies, Fingers, Food, Fluid, Fomites) |
| Clinical | Step-ladder fever, rose spots, relative bradycardia |
| Widal test | O antigen (current infection), H antigen (past/vaccine) |
| Carrier | Chronic carrier (most important source - Mary Mallon "Typhoid Mary") |
| Vaccine | TAB vaccine, Vi capsular polysaccharide vaccine |
| Treatment | Ciprofloxacin, Ceftriaxone |
6. CHOLERA
| Key Points | Detail |
|---|
| Agent | Vibrio cholerae O1 (El Tor biotype) |
| Transmission | Contaminated water & food (feco-oral) |
| Clinical | "Rice water" stools, severe dehydration, painless |
| Treatment | ORS (mainstay) + Tetracycline/Doxycycline |
| Prevention | Safe water, proper sanitation, OCV (Oral Cholera Vaccine) |
| Notification | Notifiable disease under IHR |
7. RABIES
| Key Points | Detail |
|---|
| Agent | Rhabdovirus (Lyssavirus) |
| Source | Dog bite (90% in India); also cat, bat, monkey |
| Pathology | Negri bodies in hippocampus (pathognomonic) |
| Incubation | 2-8 weeks (range 10 days to 1 year) |
| PEP | Wound wash → ARV (3/5 doses) → RIG if required |
| Pre-exposure | 3 doses of HDCV |
| 100% fatal once symptoms appear | |
8. HEPATITIS B (Serum Hepatitis)
| Key Points | Detail |
|---|
| Agent | HBV - DNA virus, Hepadnaviridae |
| Transmission | Blood & blood products, sexual, vertical (mother to child) |
| HBsAg | Surface antigen - marker of infection |
| HBeAg | Marker of infectivity (high viral load) |
| Anti-HBs | Protective antibody |
| Vaccine | 3 doses (0, 1, 6 months); given at birth under UIP |
| Chronic | >6 months = chronic HBV; risk of cirrhosis & HCC |
9. PLAGUE
| Key Points | Detail |
|---|
| Agent | Yersinia pestis |
| Vector | Blocked flea - Xenopsylla cheopis (rat flea) |
| Reservoir | Rats (Rattus rattus) |
| Types | Bubonic (most common), Pneumonic (most dangerous), Septicaemic |
| Blocked flea | Y. pestis blocks proventriculus → flea bites repeatedly → transmission |
| Treatment | Streptomycin (drug of choice), Doxycycline |
| Notifiable | International quarantinable disease |
10. MEASLES
| Key Points | Detail |
|---|
| Agent | Paramyxovirus |
| Transmission | Most infectious - droplet spread |
| Koplik's spots | Pathognomonic - on buccal mucosa before rash |
| Vaccine | MR/MMR vaccine at 9 months and 15-18 months (under UIP) |
| Complications | Pneumonia (most common cause of death), encephalitis, SSPE |
| Control | Herd immunity needed = >95% vaccination coverage |
🥉 TIER 3 - Short Notes (2 marks)
| Disease | 1 Key Point |
|---|
| Chickenpox | Varicella-zoster; highly infectious; vesicular rash in crops |
| Leprosy | M. leprae; neural & skin involvement; MDT (Multi Drug Therapy); eliminated 2005 |
| Filariasis | Wuchereria bancrofti; Culex mosquito; lymphedema; DEC drug |
| Dengue | Flavivirus; Aedes aegypti (day biting); thrombocytopenia; no vaccine approved in India |
| Japanese Encephalitis | Flavivirus; Culex mosquito; JE vaccine under UIP |
| Tetanus | Clostridium tetani; exotoxin (tetanospasmin); TT vaccine; risus sardonicus |
| Whooping Cough (Pertussis) | Bordetella pertussis; "whoop" cough; DPT vaccine |
| AIDS/HIV | HIV (Retrovirus); CD4 <200 = AIDS; NACO programme; ART treatment |
📌 Priority Order for Exam Preparation
MUST PREPARE (Long Essays):
1. Tuberculosis (TB) + NTEP
2. Malaria + NVBDCP
3. Diphtheria
4. Polio + Pulse Polio
SHORT NOTES (5 marks):
5. Typhoid / Widal test / Typhoid Mary
6. Cholera / ORS
7. Rabies / PEP
8. Hepatitis B / HBsAg
9. Plague / Blocked flea
10. Measles / Koplik spots
2-MARK DEFINITIONS:
11. Leprosy / MDT
12. Dengue / Aedes
13. HIV/AIDS
14. Tetanus / TT vaccine
Exam strategy: For any communicable disease, always cover - Agent → Transmission → Diagnosis → Treatment → Prevention/Vaccine → National Programme. This 6-point framework works for any 5-mark or 15-mark answer.