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Anatomy of the Vertebrae and Spinal Cord
Part 1: The Vertebral Column
The vertebral column forms the axial skeleton of the back and has a characteristic S-shaped curve that aligns the trunk over the center of gravity. It consists of 33 vertebrae in 5 regional groups:
FIGURE: Vertebral column showing Occiput-C2, C3-C7, T1-T12, L1-L5, Sacrum, and Coccyx (Campbell's Operative Orthopaedics 15th Ed 2026)
| Region | Number | Notes |
|---|
| Cervical (C) | 7 | Smallest; foramen transversarium in transverse processes |
| Thoracic (T) | 12 | Articulate with ribs; costal facets |
| Lumbar (L) | 5 | Largest; greatest weight-bearing |
| Sacral (S) | 5 (fused) | Fused into the sacrum in adults |
| Coccygeal | 4 (fused) | Rudimentary coccyx |
Part 2: Structure of a Typical Vertebra
All vertebrae (except atlas and axis) share the same basic elements. - Gray's Anatomy for Students, p. 83-84
FIGURE: Labeled vertebra showing vertebral body, pedicle, lamina, transverse process, spinous process, and articular processes (THIEME Atlas of Anatomy)
Key Structural Components
1. Vertebral Body
- Anterior, ovoid-shaped, weight-bearing part
- Linked to adjacent bodies by intervertebral discs and ligaments
- Size increases from C to L as weight load increases
2. Vertebral Arch (= pedicles + laminae)
- Two pedicles - bony pillars attaching arch to body; their superior/inferior notches form the intervertebral foramina
- Two laminae - flat sheets extending from each pedicle meeting in the midline; form the "roof" of the arch
3. Processes
- Spinous process - projects posteriorly/inferiorly from the junction of laminae; muscle and ligament attachment
- Transverse processes (2) - project posterolaterally from the pedicle-lamina junction; muscle/ligament attachment; articulate with ribs in the thoracic region
- Articular processes (4 total: 2 superior, 2 inferior) - form the facet (zygapophyseal) joints with adjacent vertebrae
4. Vertebral Foramen
- Space enclosed by the vertebral body anteriorly and arch posterolaterally
- All foramina together form the vertebral (spinal) canal, which houses and protects the spinal cord
Part 3: Intervertebral Discs
FIGURE: Vertebral bodies, intervertebral discs, and facet joints (lateral view)
FIGURE: Intervertebral disc structure showing nucleus pulposus, annulus fibrosus, and hyaline cartilage endplate
Each disc has:
- Nucleus pulposus - central gelatinous core; shock absorption
- Annulus fibrosus - peripheral ring of fibrocartilage lamellae; resists torsion and compression
- Hyaline cartilage endplates - interface between disc and vertebral body
Part 4: Regional Differences
Cervical Vertebrae (C1-C7)
- Smallest vertebral bodies; square-shaped from above
- Foramen transversarium in each transverse process (transmits vertebral artery)
- Spinous processes are short and bifid (C2-C6)
- Triangular vertebral foramen
- C1 (Atlas) - no vertebral body; ring-shaped; supports the skull; atlas-occipital joints allow nodding ("yes")
- C2 (Axis) - has the dens (odontoid process) projecting superiorly from its body (the fused body of C1); pivot for rotation ("no") at the atlanto-axial joint
Thoracic Vertebrae (T1-T12)
- Heart-shaped bodies; larger than cervical
- Costal facets on vertebral bodies (superior and inferior) and on transverse processes for rib articulation
- Long spinous processes pointing sharply inferiorly
- Circular vertebral foramen
Lumbar Vertebrae (L1-L5)
- Largest, kidney-shaped bodies
- Massive rectangular spinous processes
- Large triangular vertebral foramen
- Costal processes (homologous to rudimentary ribs) instead of true transverse processes
- Greatest range of flexion/extension
Sacrum & Coccyx
- 5 sacral vertebrae fused in adults; articulates with L5 above and coccyx below
- Sacral foramina for anterior and posterior sacral nerve rami
- Coccyx is vestigial and has no clinical relevance
Part 5: Anatomy of the Spinal Cord
General Features
The spinal cord is shorter than the vertebral column:
- In adults, it terminates as the conus medullaris at L1-L2
- In neonates, it ends at approximately L3
- Below the conus, nerve roots form the cauda equina ("horse's tail")
- A fibrous strand called the filum terminale extends from the conus to the coccyx
The spinal cord has two enlargements:
- Cervical enlargement (C5-T1) - gives rise to brachial plexus for the arms
- Lumbosacral enlargement (L1-S2) - gives rise to lumbar/sacral plexus for the legs
Meninges and Spaces
The spinal cord is enclosed in three protective membranes:
- Pia mater - innermost, adherent to cord surface
- Arachnoid mater - middle layer
- Dura mater - outermost, tough fibrous layer
Key spaces:
- Subarachnoid space (between pia and arachnoid) - contains cerebrospinal fluid (CSF)
- Epidural space (between dura and vertebral canal periosteum) - contains fat and venous plexuses; clinically important for epidural anesthesia
Segments
The spinal cord has 31 segments:
- 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, 1 coccygeal
Because the cord is shorter than the column, spinal cord segments do NOT align with their corresponding vertebrae - the discrepancy increases toward the lower segments.
Part 6: Internal Structure of the Spinal Cord
FIGURE: Cross-section of spinal cord showing gray matter (dorsal/ventral horns), white matter (dorsal, lateral, ventral columns), dorsal root ganglion, and spinal nerve formation (Neuroanatomy through Clinical Cases)
FIGURE: Cross-section showing butterfly-shaped gray matter with anterior and posterior horns surrounded by white matter
Gray Matter (Central - "Butterfly" or "H" Shape)
| Region | Function |
|---|
| Posterior (dorsal) horn | Sensory processing - receives afferent inputs |
| Intermediate zone | Interneurons; autonomic neurons (lateral horn at T1-L2/S2-S4) |
| Anterior (ventral) horn | Motor neurons - sends efferent outputs to muscles |
The gray matter is further divided into Rexed's laminae (I-X), each with specific functional roles.
White Matter (Surrounding Gray Matter - 3 Columns/Funiculi)
| Column | Tracts | Function |
|---|
| Dorsal (posterior) columns | Fasciculus gracilis & cuneatus | Ipsilateral fine touch, vibration, proprioception |
| Lateral columns | Lateral corticospinal tract (descending); spinothalamic tract (ascending) | Voluntary motor control; contralateral pain and temperature |
| Ventral (anterior) columns | Anterior corticospinal tract; reticulospinal, vestibulospinal tracts | Motor control; posture/balance |
Important somatotopic organization: Within tracts, cervical fibers are located most centrally and sacral fibers most peripherally. This explains why central cord lesions cause disproportionate upper limb deficits (arm > leg), and why syrinx causes a "cape" distribution of sensory loss. - Campbell's Operative Orthopaedics 15th Ed 2026, p. 2225
Part 7: Spinal Nerve Roots
FIGURE: Anterior and posterior roots merging into a spinal nerve with five branches (THIEME Atlas)
At each segmental level, two roots emerge:
- Dorsal (posterior) root - sensory; contains the dorsal root ganglion (DRG) just outside the cord, which houses sensory neuron cell bodies
- Ventral (anterior) root - primarily motor; lower motor neuron axons
These join in the intervertebral foramen to form the mixed spinal nerve, which then divides into:
- Posterior (dorsal) ramus - back muscles and skin
- Anterior (ventral) ramus - limbs and anterior trunk
Nerve Root Exit Levels (Clinically Important)
- C1-C7: exit above the pedicle of the same number (C6 root exits between C5-C6)
- C8: exits between C7 and T1 (there is no C8 vertebra)
- T1 and below: exit below the pedicle of the same number (L4 root exits between L4-L5)
Summary Table
| Feature | Cervical | Thoracic | Lumbar |
|---|
| Number | 7 | 12 | 5 |
| Body shape | Square | Heart-shaped | Kidney-shaped |
| Foramen shape | Triangular | Circular | Triangular |
| Spinous process | Short, bifid | Long, downward | Short, horizontal |
| Special feature | Foramen transversarium | Costal facets | Largest bodies |
| Cord termination | C1 starts below foramen magnum | - | Conus at L1-L2 |
Sources: - Gray's Anatomy for Students, p. 83-86 | - THIEME Atlas of General Anatomy and Musculoskeletal System, p. 102, 126 | - Neuroanatomy through Clinical Cases 3rd Ed, p. 250 | - Campbell's Operative Orthopaedics 15th Ed 2026, p. 2225 | - Forensic Anthropology: A Comprehensive Introduction, p. 115