retinopathy of prematurity screening criteria 2025 guidelines birth weight gestational age
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ROP screening criteria
Screen with a dilated retinal examination if:
Gestational age ≤30 weeks, or
Birth weight <1500 g, or
Gestational age >30 weeks with an unstable clinical course, especially if requiring cardiorespiratory support. Harriet Lane Handbook, p. 665
First examination
≤27 weeks gestation: at 31 weeks postmenstrual age (PMA)
≥28 weeks gestation: at 4 weeks chronological age
<25 weeks gestation: consider an earlier examination at 6 weeks chronological age, particularly with significant comorbidity, to identify aggressive posterior ROP early. Harriet Lane Handbook, p. 665
Criteria can vary slightly by national neonatal screening program, so follow the local NICU or ophthalmology protocol.
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