Solve it all question and answer s
| Q | Topic | Key Points |
|---|---|---|
| Q.1 | Respiratory unit, gas diffusion, IRDS | Acinus structure; Fick's Law factors; surfactant deficiency in prematurity |
| Q.2 | Spirogram | All 4 volumes + 4 capacities with values; RV measurement by He dilution; 4 importances of RV |
| Q.3 | Non-respiratory functions of lung; lung collapse prevention | 8 non-gaseous functions; 5 factors preventing atelectasis (surfactant, negative pressure, interdependence, collateral ventilation, RV) |
| Q.4 | CO₂ transport, HCO₃⁻ form, chloride shift | 3 forms (7% dissolved, 23% carbamino, 70% HCO₃⁻); carbonic anhydrase pathway; Band 3 protein exchange |
| Q.5 | ENS, BER | Myenteric + submucosal plexuses; ICC pacemaker cells; frequency per segment |
| Q.6 | Exercise, O₂-Hb curve | Rightward shift (Bohr effect); ↑CO₂, ↑H⁺, ↑temp, ↑2,3-DPG; physiological advantage = more O₂ to muscles |
| SEQ Q.7 | GI movements + peristalsis | Segmentation vs peristalsis; MMC; law of intestine mechanism in detail |
| Q | Topic | Key Points |
|---|---|---|
| Q.1 | Nephron diagram, JGA | Three JGA components: JG cells (renin), macula densa (NaCl sensor), lacis cells |
| Q.2 | GFR definition, calculation, decreasing factors | 125 mL/min; U×V/P formula; 4 factors (↓PGC, ↑PBS, ↑πGC, ↓Kf) |
| Q.3 | Complete reabsorption; Na⁺ reabsorption | Glucose, amino acids, HCO₃⁻, proteins; segment-by-segment Na⁺ mechanisms (NHE3, NKCC2, NCC, ENaC) |
| Q.4 | Concentrated urine prerequisites; countercurrent | Hyperosmotic medulla + ADH + intact loop + urea recycling; multiplier (loop) + exchanger (vasa recta) |
| Q.5 | Renal clearance; facultative reabsorption | C = UV/P; ADH → AQP2 insertion → facultative water retention in DCT/CD |
| Q.6 | Tabes dorsalis + neurogenic bladder | Sensory/flaccid neurogenic bladder; sacral afferent damage; overflow incontinence mechanism |
| SEQ Q.7 | Renal function tests | Glomerular (GFR, creatinine, cystatin C), tubular (osmolality, acidification, FENa), urinalysis, imaging, CKD staging |
| SEQ OR | Kidney and homeostasis | 9 homeostatic roles: water, electrolytes, acid-base, BP, EPO, vitamin D, gluconeogenesis, waste excretion, ECF |