HIV Disease A patient with known HIV is admitted for treatment of Pneumocystis jirovecii pneumonia (PJP) caused by HIV. A. B59, Z21 B. Z21, B59 C. B20, B59 D. B59, B20 Answ C 2. HIV Positive Without Symptoms A patient tests HIV positive during routine screening. The physician documents asymptomatic HIV infection. No HIV-related illness is present. A. B20 B. Z21 C. Z11.4 D. R75 Answer B 3. HIV with Tuberculosis A patient with HIV disease is admitted for active pulmonary tuberculosis. A. A15.0, B20 B. B20, A15.0 C. Z21, A15.0 D. B90.9, B20 Answer: B 4. HIV Pregnancy A pregnant woman in the third trimester has HIV disease and receives care for HIV management. A. B20, O98.713 B. O98.713, B20 C. Z21, O98.713 D. O99.89, B20 Answer: B 5. HIV with Kaposi Sarcoma A patient has HIV disease with Kaposi sarcoma. A. B20, C46.9 B. C46.9, B20 C. Z21, C46.9 D. R75, C46.9 Answer: A 6. HIV Exposure A healthcare worker experiences a needlestick from an HIV-positive patient. The worker is not infected. A. Z20.6 B. Z21 C. B20 D. R75 Answer: A 7. Inconclusive HIV Test The physician documents inconclusive HIV laboratory findings. A. B20 B. Z21 C. R75 D. Z20.6 Answer: C 8. HIV Disease with Oral Candidiasis A patient with HIV disease has oral candidiasis. A. B37.0, B20 B. B20, B37.0 C. Z21, B37.0 D. R75, B37.0 An B 9. HIV Disease History A patient previously diagnosed with HIV disease is admitted for bacterial pneumonia unrelated to HIV. A. Z21 B. B20, J15.9 C. J15.9 only Ans B 10. New HIV Diagnosis with Symptoms A newly diagnosed patient has HIV infection with cryptococcal meningitis. A. B45.1, Z21 B. B20, B45.1 C. R75, B45.1 D. Z20.6, B45.1 Ans B

Here's a breakdown of all 10 HIV ICD-10-CM coding questions with explanations:

ICD-10-CM HIV Coding - Key Codes

CodeMeaning
B20HIV disease (symptomatic / AIDS)
Z21Asymptomatic HIV infection status
R75Inconclusive laboratory evidence of HIV
Z20.6Contact with / exposure to HIV
Z11.4Screening for HIV

Question-by-Question Explanations


1. HIV Disease + PJP - Answer: C (B20, B59)

B20 is sequenced first because the patient has HIV disease (symptomatic - PJP is an AIDS-defining illness). PJP (B59) is coded as an additional/manifestation code. The rule: when HIV disease is present alongside any associated condition, B20 leads.

2. Asymptomatic HIV - Answer: B (Z21)

The physician explicitly documents asymptomatic HIV infection with no HIV-related illness. Z21 is used only when the patient is HIV-positive but has no symptoms and no HIV-related conditions. B20 is reserved for symptomatic/AIDS-stage disease.

3. HIV Disease + Tuberculosis - Answer: B (B20, A15.0)

B20 is sequenced first per ICD-10-CM guidelines: when a patient has HIV disease and is admitted for an HIV-related condition (TB is an AIDS-defining condition), B20 is the principal diagnosis. A15.0 (pulmonary TB) follows.

4. HIV in Pregnancy - Answer: B (O98.713, B20)

In pregnancy, obstetric codes take precedence. O98.713 (HIV complicating pregnancy, third trimester) is principal. B20 follows as an additional code. The OB code always leads when the patient is pregnant - this is a core ICD-10-CM sequencing rule.

5. HIV + Kaposi Sarcoma - Answer: A (B20, C46.9)

B20 leads because the patient has HIV disease (Kaposi sarcoma is an AIDS-defining malignancy, confirming B20 status). C46.9 (Kaposi sarcoma, unspecified) is additional. Same sequencing principle as Q1 and Q3.

6. HIV Exposure (Needlestick) - Answer: A (Z20.6)

The worker was exposed but not infected. Z20.6 = contact with and (suspected) exposure to HIV. This is distinct from Z21 (confirmed positive but asymptomatic) and B20 (confirmed disease). No infection = no B20 or Z21.

7. Inconclusive HIV Test - Answer: C (R75)

R75 = inconclusive laboratory evidence of HIV. Used when test results are indeterminate and diagnosis is neither confirmed nor ruled out. Do not assign B20 or Z21 without confirmed diagnosis.

8. HIV Disease + Oral Candidiasis - Answer: B (B20, B37.0)

B20 leads (HIV disease present), B37.0 (oral candidiasis) follows. Oral candidiasis is an AIDS-defining condition, confirming B20 is appropriate. Same rule applies: B20 first, manifestation/associated condition second.

9. History of HIV Disease + Unrelated Pneumonia - Answer: B (B20, J15.9)

Critical rule: Once a patient has been diagnosed with HIV disease (B20), you never downgrade to Z21, even if the current admission is for an unrelated condition. HIV disease is a permanent code - B20 is always assigned. J15.9 (bacterial pneumonia) is additional.

10. New HIV Diagnosis + Cryptococcal Meningitis - Answer: B (B20, B45.1)

Cryptococcal meningitis (B45.1) confirms symptomatic HIV disease, so B20 is correct (not Z21 or R75). B20 leads; B45.1 follows as the associated condition. A new diagnosis presenting with an AIDS-defining illness = B20 from the start.

Core Sequencing Rules Summary

  1. B20 always leads when HIV disease is present with associated conditions
  2. Obstetric codes lead in pregnancy (O98.7xx first, then B20)
  3. Z21 = asymptomatic only - no symptoms, no HIV-related illness
  4. Once B20, always B20 - never revert to Z21 after HIV disease is established
  5. R75 = inconclusive lab only (not a confirmed diagnosis)
  6. Z20.6 = exposure without infection
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