For most adults, common options are:

Do not drive, drink alcohol, or combine with sedatives after taking these unless a clinician says it is safe. Dry mouth, blurred vision, constipation, and urinary difficulty can occur, especially with scopolamine.

Avoid scopolamine or get pharmacist/clinician advice first if the person has glaucoma, difficulty urinating or enlarged prostate, is pregnant, takes other sedating or anticholinergic drugs, or is treating a child. The CDC notes that non-drowsy allergy medicines such as loratadine, cetirizine, and fexofenadine generally do not work for motion sickness. CDC travel guidance recommends taking medication before the motion exposure, rather than waiting until symptoms begin.

If vomiting is severe, there is a bad headache, chest pain, weakness, fainting, or symptoms persist off the ride/trip, seek medical care.