Syp ondan peds dose
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Reading File
Reading File
Syrup Ondansetron — Pediatric Dose
Standard Dose
0.15 mg/kg PO — single oral dose (syrup or ODT)
Weight-Based Simplified Dosing (easier to use in practice)
| Weight | Dose |
|---|---|
| 8–15 kg | 2 mg |
| 15–30 kg | 4 mg |
| >30 kg | 8 mg |
Key Points
- Indication: Vomiting in acute gastroenteritis, as adjunct to oral rehydration therapy (ORT)
- Timing: Start ORT 15–30 minutes after giving ondansetron
- Age: Most studies include children ≥6 months; some IV studies go down to 1 month
- Single dose is sufficient — multiple doses add side effects without extra benefit
- Route: PO preferred (syrup or ODT); IV use not routinely supported for this indication
- Side effects: Mild, self-limited diarrhea; QT prolongation (~10–17 msec) — clinically insignificant in healthy children
- Avoid dopamine antagonists (promethazine, metoclopramide) in children due to extrapyramidal reactions and respiratory depression risk
— Roberts and Hedges' Clinical Procedures in Emergency Medicine; Tintinalli's Emergency Medicine
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