Q: Write a short note with important points for My MD Anaesthesiology exam reference from Anesthesia books Q: Write a notes on diastolic dysfunction and its importance in Anaesthesiology A: These notes cover everything you need for your MD Anaesthesiology exam on diastolic dysfunction. Here's a quick orientation to the structure: What's covered: 1. Physiology - the four phases of diastole with the physiological basis for dysfunction 2. Causes - the four basic mechanisms with clinically relevant associations 3. Pathophysiology - active vs. passive components, the P-V relationship, and the HFpEF concept a common exam question 4. Echo grading - all four grades including the classic pseudonormal trap with E/A, DT, IVRT, e', and E/e' ratios in a table 5. Anaesthetic significance - seven reasons why this matters perioperatively 6. Perioperative management - pre/intra/postoperative goals in a table format 7. Drug effects - each agent's impact on diastolic function 8. Special contexts - cardiac surgery, elderly, sepsis, obstetrics 9. Quick recall box - for last-minute revision before the exam High-yield exam points to memorise: - E/e' 15 = elevated LVEDP regardless of E/A appearance - Pseudonormal pattern Grade II has normal E/A but low e' - tissue Doppler is the key to unmask it - Atrial contraction contributes 20-40% of CO in dysfunction - loss of sinus rhythm is catastrophic - Vasopressors fluid boluses when managing hypotension in these patients - Normal EF does not exclude haemodynamically significant diastolic heart failure