Ibrufen pediatric dosage

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Here is a summary of ibuprofen (Ibrufen) pediatric dosing from authoritative medical textbooks:

Ibuprofen — Pediatric Dosage

Standard Dosing

ParameterDetails
Dose10 mg/kg per dose, orally
FrequencyEvery 6–8 hours
Maximum daily dose40 mg/kg/day, never exceeding 3,200 mg/day
Minimum age≥ 6 months — contraindicated in infants < 6 months
Ibuprofen is the NSAID of choice in pediatric patients due to its favorable side-effect profile compared to other NSAIDs.

Indications in Children

  • Fever (antipyretic)
  • Pain (analgesic) — mild to moderate
  • Inflammatory conditions (e.g., juvenile idiopathic arthritis — higher doses under specialist guidance)
  • Postoperative pain (in combination with other analgesics)

Key Safety Points

  • Avoid in infants < 6 months — pharmacokinetic differences and ongoing renal development make it unsafe in this age group.
  • Renal caution: NSAIDs (including ibuprofen) can impair renal function; use with caution in dehydrated children.
  • GI effects: COX-1 inhibition can cause GI irritation; administer with food.
  • Do not use aspirin as an alternative in children — risk of Reye syndrome.
  • Alternating with acetaminophen (paracetamol) may offer slightly better fever/pain control but increases complexity and risk of dosing errors.

Quick Reference by Weight (10 mg/kg, q6–8h)

WeightApproximate Dose
8 kg (approx. 6–9 months)80 mg
12 kg (approx. 1–2 years)120 mg
16 kg (approx. 3–4 years)160 mg
20 kg (approx. 5–6 years)200 mg
25 kg (approx. 7–8 years)250 mg
30 kg (approx. 9–10 years)300 mg
(Oral suspension typically available as 100 mg/5 mL)

Sources: ROSEN's Emergency Medicine (Table 171.2), Campbell Walsh Wein Urology (Table 26.3), Cummings Otolaryngology
Clinical note: Always dose by weight (mg/kg), not age. Use weight-based dosing charts and confirm the formulation concentration before dispensing to caregivers.
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