Difference between bundle branch block and Mobitz Type 2 block

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"bundle branch block" AND "atrioventricular block"

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Merck Manual bundle branch block Mobitz type II atrioventricular block ECG

Both involve the ventricular conduction system, but they interrupt conduction at different levels and produce different ECG findings.
FeatureBundle branch block (BBB)Mobitz type II AV block
Where conduction failsIn the right or left bundle branch, after the His bundleUsually in the His-Purkinje system, below the AV node
What happens to atrial-to-ventricular conductionEvery P wave is usually conducted to a QRSSome P waves are suddenly not conducted, so a QRS is dropped
PR intervalUsually normal or unchangedConstant in conducted beats, then an unexpected nonconducted P wave
QRS widthTypically wide, at least 120 ms in complete BBBOften wide because the underlying disease is in the His-Purkinje system, but it can be narrow if the block is intra-Hisian
Key ECG patternWide, altered QRS morphology: RBBB or LBBB patternRegular P waves with intermittent missing QRS complexes, without preceding PR prolongation
Clinical implicationMay be incidental or reflect structural/ischemic heart disease, depending on type and contextPathologic and higher risk: can abruptly progress to complete heart block, often requiring a permanent pacemaker

The simplest distinction

  • BBB: the electrical impulse still reaches the ventricles, but travels slowly through an alternative route. Thus, there is a wide QRS.
  • Mobitz II: some electrical impulses from the atria do not reach the ventricles at all. Thus, there are dropped QRS complexes.

Example

Right bundle branch block: P → wide QRS, P → wide QRS, P → wide QRS
Every P wave produces a QRS, but each QRS is broad.
Mobitz II: P → QRS, P → QRS, P → no QRS, P → QRS
PR intervals before conducted QRS complexes stay the same, then one P wave is not followed by a QRS.
They can coexist. For example, Mobitz II with a pre-existing bundle branch block suggests more extensive His-Purkinje disease and is concerning. Merck's AV-block reference notes that Mobitz II commonly progresses to complete heart block. Harrison's describes bundle branch block as a conduction delay/block in a bundle branch, producing characteristic ventricular conduction patterns. Harrison’s Principles of Internal Medicine, 22e, section “Bundle Branch Blocks and Related Patterns.”
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