Presentation on morphine with full details and all the doses
Morphine Pharmacology
Presentation · PPTX
| Slide | Topic |
|---|---|
| 1 | Title slide |
| 2 | Table of contents |
| 3 | History & classification |
| 4 | Chemistry & structure-activity relationships |
| 5 | Mechanism of action (μ-receptor, GPCR pathways, sites of action) |
| 6 | Pharmacokinetics – ADME (with M3G/M6G detail) |
| 7 | Key PK parameters table |
| 8 | CNS pharmacodynamics |
| 9 | Systemic effects (CV, respiratory, GI, GU, endocrine) |
| 10 | Clinical uses / indications |
| 11 | Oral dosing – IR and ER tables (adults, elderly, pediatric) |
| 12 | Parenteral dosing – IV, IM, SC tables (all age groups) |
| 13 | Neuraxial dosing – epidural & intrathecal (preservative-free) |
| 14 | PCA settings + continuous infusion doses |
| 15 | Equianalgesic dose table (morphine vs. fentanyl, hydromorphone, oxycodone, etc.) |
| 16 | Special populations (elderly, renal, hepatic, pediatric, pregnancy, obesity) |
| 17 | Adverse effects table with management |
| 18 | Contraindications, precautions, FDA Black Box Warning |
| 19 | Drug interactions table |
| 20 | Overdose triad + Naloxone dosing (IV/IM/IN) |
| 21 | Tolerance, dependence & withdrawal |
| 22 | Opioid use disorder & safe prescribing |
| 23 | Quick reference summary card |
| 24 | References |
Create a dosing cheat sheet PDF for quick clinical reference
Morphine Dosing CheatSheet
PDF Document · PDF
| Column | Sections |
|---|---|
| Left (navy/amber) | Pharmacokinetics snapshot · Mechanism of action · Key adverse effects |
| Middle (multi-color) | Oral IR dosing · Oral ER dosing · IV dosing · IM/SC dosing · PCA settings |
| Right (red/green) | Neuraxial (epidural/intrathecal) · Equianalgesic table · Special populations · Overdose triad + Naloxone reversal doses |