Prescription terminologies

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Prescription Terminologies

A prescription has a standard structure and uses a set of traditional (mostly Latin-derived) abbreviations. Here's a breakdown, based on Katzung's Basic and Clinical Pharmacology chapter on Rational Prescribing & Prescription Writing plus standard pharmacology reference.

1. Parts of a Prescription

PartDescription
SuperscriptionDate, patient's name, age, address, weight (for pediatric/weight-based dosing)
Rx symbol"Recipe" - Latin for "take thou" - the traditional heading of a prescription
InscriptionName and strength/dose of the drug prescribed
SubscriptionDispensing instructions to the pharmacist (e.g., quantity to dispense, form)
Signatura (Sig)Instructions to the patient on how to take the medication - what actually appears on the medicine label
Prescriber's signature/DEA numberLegal validation, required for controlled substances

2. Common Latin Abbreviations Used in the "Sig" (Directions)

Frequency/Timing
  • qd - every day (largely discouraged now due to error potential; write "daily")
  • bid - twice a day (bis in die)
  • tid - three times a day (ter in die)
  • qid - four times a day (quater in die)
  • q4h, q6h, q8h - every 4/6/8 hours
  • qhs - every night at bedtime (quaque hora somni)
  • qam / qpm - every morning / every evening
  • prn - as needed (pro re nata)
  • stat - immediately (statim)
  • ac - before meals (ante cibum)
  • pc - after meals (post cibum)
Route of Administration
  • po - by mouth (per os)
  • pr - per rectum
  • pv - per vagina
  • IM - intramuscular
  • IV - intravenous
  • SC/SQ - subcutaneous
  • SL - sublingual
  • top - topically
  • inh - by inhalation
  • gtt - drops (guttae)
Quantity/Dose
  • tab - tablet
  • cap - capsule
  • ml/cc - milliliter/cubic centimeter
  • gm/mg/mcg - gram/milligram/microgram
  • ss - one-half (semis)
  • ut dict / UD - as directed (ut dictum)
Dispensing Instructions
  • disp - dispense
  • # - number (quantity to dispense)
  • NR - no refill
  • Rep / refill x__ - number of refills
  • NS - normal saline
  • D5W - dextrose 5% in water

3. Important Safety Note (from Katzung, highlighted as a common source of prescribing error)

Certain abbreviations are now flagged as error-prone by patient safety organizations (e.g., ISMP, Joint Commission) and should be avoided in favor of writing the term out in full:
  • qd (once daily) - easily misread as qid (four times daily) → write "daily"
  • U (units) - misread as "0" (zero), causing 10-fold overdose → write "units"
  • μg (microgram) - misread as "mg" → write "mcg"
  • Trailing zeros (e.g., 1.0 mg) - misread as 10 mg → write "1 mg"
  • No leading zero (e.g., .5 mg) - misread as 5 mg → write "0.5 mg"
Katzung's chapter explicitly notes: "Poor prescription writing is traditionally exemplified by illegible handwriting. However, other types of poor writing are common and often more dangerous. One of the most important is the misplaced or omitted decimal point..." - Katzung's Basic and Clinical Pharmacology, 16th Ed., Ch. 66.

4. Other Key Terms

  • Generic name vs. Brand (trade) name - the drug's official nonproprietary name vs. its manufacturer's marketed name
  • DAW - dispense as written (no generic substitution)
  • NDC - National Drug Code, unique product identifier
  • e-prescribing (e-Rx) - electronic transmission of prescriptions, now standard/mandated in many jurisdictions and reduces handwriting-related errors
If you want, I can go deeper into a specific area, such as controlled-substance prescription requirements (DEA schedules, triplicate forms) or pediatric weight-based prescription writing.
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