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Summarization of Data, Measures of Central Tendency & Averages
What Is Data Summarization?
Descriptive statistics condense large sets of observations into a few representative numbers. In any study or dataset, continuous variables (age, weight, lab values) are typically described with two complementary statistics:
- A measure of central tendency - a single value representing where data clusters
- A measure of spread - indicating variability around that center (standard deviation, range, IQR)
This summary is the foundation of presenting baseline characteristics in research and clinical studies. - Rockwood and Green's Fractures in Adults, 10th ed., p. [block 3]
The Three Core Measures of Central Tendency
1. Mean (Arithmetic Mean) - Parametric
The mean is the most widely recognized measure of central tendency:
$$\bar{x} = \frac{x_1 + x_2 + \cdots + x_n}{n} = \frac{\sum_{i=1}^n x_i}{n}$$
- Calculated from a defined formula - therefore called a parametric method
- Sensitive to outliers and extreme values
- Best used when data are normally (Gaussian) distributed
- The preferred summary statistic for normally distributed continuous data
Example: Patient ages 45, 50, 55, 60, 65 → Mean = 275/5 = 55 years
2. Median - Nonparametric
The median divides all data points exactly in half - one half above, one half below. It is also called the 50th percentile.
- Not derived from a formula - taken from a direct count of data points - therefore called a nonparametric method
- Resistant to outliers and extreme values
- Preferred when data are skewed or non-normally distributed
- Appropriate for ordinal variables (e.g., pain scales 0-5)
Example: Ages 45, 50, 55, 60, 90 → Median = 55 years (mean would be 60, pulled up by outlier 90)
3. Mode
The mode is the most frequently occurring value in a dataset.
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Not very useful for describing or comparing most datasets
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Has a role when a dataset consists of two or more subpopulations (called a bimodal distribution)
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Skewed data does NOT affect the mode
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Henry's Clinical Diagnosis and Management by Laboratory Methods
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Quick Compendium of Clinical Pathology, 5th ed.
The Geometric Mean
The geometric mean minimizes the influence of extreme values and is calculated as the nth root of the product of all n values:
$$\text{Geometric Mean} = \sqrt[n]{x_1 \times x_2 \times \cdots \times x_n}$$
A mathematically equivalent and more convenient formula:
$$\log(\text{Geometric Mean}) = \frac{\sum_{i=1}^n \log x_i}{n}$$
(Take the antilog of the result to get the geometric mean.)
When to use it: When data are heavily skewed toward lower values with some high outliers. For example, the dataset 3, 3, 4, 4, 5, 5, 5, 6, 6, 8, 9, 10, 15, 21 has:
- Arithmetic mean = 7.2
- Geometric mean = 6.09 (better reflects the preponderance of low values)
The geometric mean is also appropriate for ratios, growth rates, and logarithmically distributed data (e.g., antibody titers, infection rates).
- Henry's Clinical Diagnosis and Management by Laboratory Methods
Relationship Between Mean, Median & Mode in Different Distributions
| Distribution | Relationship | Best Measure |
|---|
| Symmetric (normal/Gaussian) | Mean = Median = Mode | Mean |
| Positively skewed (right tail) | Mean > Median > Mode | Median |
| Negatively skewed (left tail) | Mean < Median < Mode | Median |
| Bimodal | Two peaks | Mode (or report both peaks) |
In a positively skewed dataset, the mean is pulled toward the high-value tail, making it unrepresentative. The median is more stable. - Quick Compendium of Clinical Pathology, 5th ed.
The Normal (Gaussian) Distribution
The Gaussian distribution is symmetric and bell-shaped, centered on the mean. In a perfect Gaussian distribution, mean = median = mode.
Figure: Areas under the normal curve - Henry's Clinical Diagnosis
| Range | % of Data Included |
|---|
| Mean ± 1 SD | 68.2% |
| Mean ± 2 SD | 95.5% |
| Mean ± 3 SD | 99.7% |
Measures of Spread (Alongside Central Tendency)
Central tendency alone is incomplete. Spread must always be reported:
| Measure | Used With | Notes |
|---|
| Standard Deviation (SD) | Mean (normal data) | SD = √[Σ(x - mean)²/(n-1)] |
| Range | Median (skewed data) | Lowest to highest value |
| Interquartile Range (IQR) | Median (skewed data) | Middle 50% of values (excludes top and bottom quartiles) |
- Rockwood and Green's Fractures in Adults
Parametric vs. Nonparametric Summary
| Feature | Parametric (Mean) | Nonparametric (Median) |
|---|
| Assumes distribution? | Yes (normal) | No |
| Sensitive to outliers? | Yes | No |
| Enables further statistical tests? | Many (t-test, ANOVA) | Fewer (Mann-Whitney, etc.) |
| Best data type | Continuous, normally distributed | Skewed, ordinal, or non-normal |
Quick Selection Guide
- Normally distributed continuous data (e.g., height, weight, lab values in healthy population) → Mean ± SD
- Skewed continuous data (e.g., income, hospital length of stay, troponin levels) → Median [IQR]
- Ordinal data (e.g., pain scale, functional scores) → Median
- Categorical/nominal data → Frequency and proportion (%)
- Ratio/growth rate data → Geometric mean
Sources: Henry's Clinical Diagnosis and Management by Laboratory Methods; Quick Compendium of Clinical Pathology, 5th ed.; Rockwood and Green's Fractures in Adults, 10th ed. 2025; Australian Bureau of Statistics - Central Tendency