You are a medical biochemistry expert. Search the medical textbook library database and compile detailed notes on the following topics. Use query_library_db to search, then read_file to get content. TOPICS TO RESEARCH: 1. Calcium homeostasis (regulation by PTH, calcitonin, Vitamin D; hypercalcemia/hypocalcemia) 2. Urea cycle (diagram/steps, enzymes, disorders) 3. Iron absorption and mucosal block theory 4. Lesch-Nyhan syndrome and orotic aciduria For each topic: - Use headings_fts and paragraphs_fts to find relevant sections - Read the actual file content using read_file - Extract: key mechanisms, enzymes, clinical features, diagrams described SQL examples: SELECT title, book_title, '/textbooks/' || block_file_path AS file_path, line_number, para_line_ranges FROM headings_fts WHERE headings_fts MATCH 'calcium homeostasis' ORDER BY rank LIMIT 5 SELECT book_title, section_heading, '/textbooks/' || block_file_path AS file_path, line_start, line_end, snippet(paragraphs_fts, 0, '>>>', '<<<', '...', 40) as snippet FROM paragraphs_fts WHERE paragraphs_fts MATCH 'mucosal block iron absorption' ORDER BY rank LIMIT 5 Return ALL findings as detailed, structured notes ready for exam preparation. Include mechanisms, key points, clinical correlations. Format with clear headings for each topic.

You are a medical biochemistry expert. Search the medical textbook library database and compile detailed notes on the following topics. Use query_library_db to search, then read_file to get content. TOPICS TO RESEARCH: 1. Products obtained from glycine (bile salts, creatine, heme, purines, glutathione, hippuric acid, conjugation reactions) 2. Purine catabolism (pathway to uric acid, enzymes, gout, xanthine oxidase) 3. Transamination and deamination reactions (aminotransferases, pyridoxal phosphate, oxidative deamination, glutamate dehydrogenase) 4. Van den Bergh reaction (direct vs indirect bilirubin, clinical significance, types of jaundice) 5. Kwashiorkor and Marasmus (differences, pathophysiology, clinical features, lab findings) 6. Phenylketonuria (PKU) - enzyme defect, metabolites, clinical features, treatment 7. Rickets (Vitamin D deficiency, types, clinical features, biochemical changes, X-ray findings) 8. Scurvy (Vitamin C deficiency, collagen synthesis role, clinical features, treatment) 9. Trousseau's sign (hypocalcemia sign, mechanism) 10. ESSAY topics: Vitamin D (synthesis, activation, functions, deficiency), Vitamin C (functions, deficiency, sources), Vitamin B12 (absorption, functions, deficiency, pernicious anemia), Calcium metabolism (regulation, functions, disorders) For each topic use: SELECT title, book_title, '/textbooks/' || block_file_path AS file_path, line_number, para_line_ranges FROM headings_fts WHERE headings_fts MATCH '[topic]' ORDER BY rank LIMIT 5 Then read_file to get actual content. Return ALL findings as detailed, structured notes ready for exam preparation with clear headings. Include mechanisms, clinical features, key enzymes, and distinguishing points.